Diet, Weight Management, Physical activity and Ovarian & Breast Cancer Risk in Women With BRCA1/2 Pathogenic Germline Gene Variants: Systematic Review

Authors

Adriana M Coletta
Susan K Peterson
Leticia A Gatus
Kate J Krause
Susan M Schembre
Susan C Gilchrist
Banu Arun
Y Nancy You
Miguel A Rodriguez-Bigas
Larkin L Strong
Karen H Lu
Karen Basen-Engquist

Language

English

Publication Date

1-1-2020

Journal

Hereditary Cancer in Clinical Practice

DOI

10.1186/s13053-020-0137-1

PMID

32165993

PMCID

PMC7060535

PubMedCentral® Posted Date

March 2020

PubMedCentral® Full Text Version

Post-print

Abstract

INTRODUCTION: Women with pathogenic germline gene variants in

METHODS: We searched Medline, EMBASE, CENTRAL, PubMed, and clinicaltrials.gov up to October 3, 2019. We identified 2775 records and included 21.

RESULTS: There is limited evidence related to these factors and ovarian cancer risk. For breast cancer risk, evidence suggests higher diet quality, adulthood weight-loss of ≥10 pounds, and activity during adolescence and young-adulthood may be linked with decreased risk. Higher meat intake and higher daily energy intake may be linked with increased risk.

CONCLUSIONS: There is not enough evidence to suggest tailored recommendations for dietary habits or weight management among women with

Keywords

BRCA, Breast Cancer, Ovarian Cancer, Diet, Physical activity, Weight

Recommended Citation

Coletta, Adriana M; Peterson, Susan K; Gatus, Leticia A; et al., "Diet, Weight Management, Physical activity and Ovarian & Breast Cancer Risk in Women With BRCA1/2 Pathogenic Germline Gene Variants: Systematic Review" (2020). Faculty, Staff and Student Publications. 271.
https://digitalcommons.library.tmc.edu/uthsph_docs/271