Student and Faculty Publications
Publication Date
11-20-2023
Journal
International Journal of Molecular Sciences
Abstract
The insulin resistance caused by impaired glucose metabolism induces ovarian dysfunction due to the central importance of glucose as a source of energy. However, the research on glucose metabolism in the ovaries is still lacking. The objectives of this study were to analyze the effect of PD-MSCs on glucose metabolism through IGFBP2-AMPK signaling and to investigate the correlation between glucose metabolism and ovarian function. Thioacetamide (TAA) was used to construct a rat injury model. PD-MSCs were transplanted into the tail vein (2 × 10
Keywords
Rats, Animals, Thioacetamide, AMP-Activated Protein Kinases, Mesenchymal Stem Cells, Signal Transduction, Glucose, Mesenchymal Stem Cell Transplantation