Language
English
Publication Date
1-8-2023
Journal
International Journal of Environmental Research and Public Health
DOI
10.3390/ijerph20021104
PMID
36673858
PMCID
PMC9858656
PubMedCentral® Posted Date
1-8-2023
PubMedCentral® Full Text Version
Post-print
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic, required the donning of personal protective equipment during clinical contact, and continues to be a significant worldwide public health concern. Pediatric cardiac arrest is a rare but critical condition with a high mortality rate, the outcomes of which may be negatively affected by donning personal protective equipment. The aim of this study is to perform a systematic review and meta-analysis of the impact of the COVID-19 pandemic on pediatric cardiac arrest outcomes. We conducted a systematic review with meta-analysis in the following databases: PubMed, EMBASE, Scopus, Web of Science, and Cochrane Library from their inception to 1 October 2022. We included studies published in English on pediatric patients with cardiac arrest, dichotomized by the pre- and during-COVID-19 periods and then stratified by COVID-19 positive or negative status, to evaluate clinical outcomes associated with cardiac arrest. Six studies were included in the meta-analysis. In witnessed out-of-hospital cardiac arrest patients, there were no differences between the pandemic and pre-pandemic periods for witnessed cardiac arrest (28.5% vs. 28.7%; odds ratio (OR) = 0.99; 95% confidence interval (CI): 0.87 to 1.14; p = 0.93), administration of bystander cardiopulmonary resuscitation (61.5 vs. 63.6%; OR = 1.11; 95%CI: 0.98 to 1.26; p = 0.11), bystander automated external defibrillator use (both 2.8%; OR = 1.00; 95%CI: 0.69 to 1.45; p = 0.99), return of spontaneous circulation(8.4 vs. 8.9%; OR = 0.93; 95%CI: 0.47 to 1.88; p = 0.85), survival to hospital admission (9.0 vs. 10.2%, OR = 0.81; 95%CI: 0.45 to 1.44; p = 0.47), or survival to hospital discharge (13.4 vs. 12.4%; OR = 0.62; 95%CI: 0.22 to 1.72; p = 0.35). COVID-19 did not change pediatric cardiac arrest bystander interventions or outcomes.
Keywords
Humans, Child, Pandemics, COVID-19, SARS-CoV-2, Cardiopulmonary Resuscitation, Out-of-Hospital Cardiac Arrest, Emergency Medical Services
Published Open-Access
yes
Recommended Citation
Navolokina, Alla; Smereka, Jacek; Böttiger, Bernd W; et al., "The Impact of COVID-19 on Pediatric Cardiac Arrest Outcomes: A Systematic Review and Meta-Analysis" (2023). Faculty and Staff Publications. 3072.
https://digitalcommons.library.tmc.edu/baylor_docs/3072
Included in
Cardiology Commons, Cardiovascular Diseases Commons, Clinical Epidemiology Commons, Community Health and Preventive Medicine Commons, Congenital, Hereditary, and Neonatal Diseases and Abnormalities Commons, COVID-19 Commons, Critical Care Commons, Environmental Public Health Commons, Medical Sciences Commons, Pediatrics Commons