Baylor College of Medicine is a health sciences university that creates knowledge and applies science and discoveries to further education, healthcare and community service locally and globally. Learn more about our mission, vision and values.

Manuscripts submitted for publication (preprints), peer-reviewed pre-publication articles (postprints), and published articles from the faculty of Baylor College of Medicine are posted here with additional links to supplemental data.

Ranked 20th in the nation, and first in Texas since 2006 for obtaining National Institutes of Health (NIH) funding, Baylor College of Medicine received $687 million in total funding from 2,792 sponsored project awards in fiscal year 2023. Baylor operates more than 90 research and patient-care centers and units. BCM also operates more than 27 Advanced Technology Core Laboratories that provide services for studies in areas like metabolomics, proteomics, pathology, and genomics.

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Submissions from 2025

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A Hierarchy of Pdz Domain Scaffolding Proteins Clusters the Kv1 K+ Channel Protein Complex at the Axon Initial Segment, Wei Zhang, Victoria L Palfini, Yu Wu, et al.

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Core Domain Set for Chronic and/or Recurrent Manifestations of Calcium Pyrophosphate Deposition Disease: Omeract Delphi Survey To Establish Consensus, Yiling Zhang, Sara K Tedeschi, Abhishek Abhishek, et al.

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Core Domain Set for Studies of Acute Calcium Pyrophosphate Crystal Arthritis: Omeract Delphi Survey To Establish Consensus, Yiling Zhang, Sara K Tedeschi, Abhishek Abhishek, et al.

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Pan-Cancer, Multi-Omic Correlates of Survival Transcending Tumor Lineage Across 11,019 Patients Reveal Targets and Pathways, Yiqun Zhang, Fengju Chen, and Chad J Creighton

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Stereoelectroencephalography Reveals Neural Signatures of Multisensory Integration in the Human Superior Temporal Sulcus during Audiovisual Speech Perception, Yue Zhang, John F Magnotti, Xiang Zhang, et al.

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Lung NR3C1+ and CXCR6high T Cells Distinguish Immunopathogenesis of Human Emphysema, Yun Zhang, Maor Sauler, David B Corry, et al.

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A Natural Small Molecule Isoginkgetin Alleviates Hypercholesterolemia and Atherosclerosis by Targeting ACLY, Zhidan Zhang, Meijie Chen, Yitong Xu, et al.

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Racial Disparities in Clonal Hematopoiesis and Their Impact on Hematologic Malignancies, Zijian Zhang and Chao Cheng

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Associations of Long-Term Exposure to Temperature With Coronary Artery Calcification Risk Among Middle-Aged Adults: The Coronary Artery Risk Development in Young Adults (Cardia) Study, Dandan Zhao, Jie Yao, Yuanfei Li, et al.

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Clinical Validation of RNA Sequencing for Mendelian Disorder Diagnostics, Sen Zhao, Kristina Macakova, Jefferson C Sinson, et al.

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The Utility of Ultra-Deep RNA Sequencing in Mendelian Disorder Diagnostics, Sen Zhao, Jefferson C Sinson, Shenglan Li, et al.

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The Adiponectin-PPARγ Axis in Hepatic Stellate Cells Regulates Liver Fibrosis, Shangang Zhao, Qingzhang Zhu, Wang-Hsin Lee, et al.

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Alzheimer’s Disease Protective Allele of Clusterin Modulates Neuronal Excitability Through Lipid-Droplet-Mediated Neuron-Glia Communication, Xiaojie Zhao, Yan Li, Siwei Zhang, et al.

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NF1-Depleted Er+ Breast Cancers Are Differentially Sensitive to CDK4/6 Inhibitors, Ze-Yi Zheng, Anran Chen, Eric J Jaehnig, et al.

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Clair3-RNA: A Deep Learning-Based Small Variant Caller for Long-Read RNA Sequencing Data, Zhenxian Zheng, Xian Yu, Lei Chen, et al.

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Targeting Adenosine 2A Receptor Signaling Suppresses Vascular Calcification by Restraining Smooth Muscle Osteogenic Differentiation, Yaqi Zhou, Dingwei Zhao, Qian Ma, et al.

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Endothelial Adenosine Receptor 2A Loss Alleviates Diabetic Vascular Calcification by Blocking CREB1-SNAI1-Driven EndMT, Yaqi Zhou, Dingwei Zhao, Qian Ma, et al.

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Focal Adhesion Kinase Drives Rho/ROCK and mTOR Signaling to Protect and Augment Aortic Dissections, Zhen Zhou, Pujun Guan, Ripon Sarkar, et al.

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Glucagon-Like Peptide-1 Receptor Agonists in Neurodegenerative Diseases: Promises and Challenges, Zhi Dong Zhou, Lingxiao Yi, Karolina Popławska-Domaszewicz, et al.

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Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation, Duolong Zhu, Jeffrey Galley, Jason Pizzini, et al.

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Control of Clostridioides difficile Virulence and Physiology by the Flagellin Homeostasis Checkpoint FliC-FliW-CsrA in the Absence of Motility, Duolong Zhu, Katherine J Wozniak, Firas Midani, et al.

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Integrative Spatial Omics Reveals Distinct Tumor-Promoting Multicellular Niches and Immunosuppressive Mechanisms in Black American and White American Patients With TNBC, Qian Zhu, Akhila Balasubramanian, Jaya Ruth Asirvatham, et al.

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Oxidative Stress Promotes Lipid-Laden Macrophage Formation via CYP1B1, Yin Zhu, Saugata Dutta, Yohan Han, et al.

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CYP1B1 Mediates Cigarette Smoke-Induced Lipid Accumulation in Alveolar Type 2 Cells, Yin Zhu, Siddhika Gamare, Francesca Polverino, et al.

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Application of a Digital Quality Measure for Cancer Diagnosis in Epic Cosmos, Andrew J Zimolzak, Sundas P Khan, Hardeep Singh, et al.