Accuracy and Safety of Scout Dose Resin Yttrium-90 Microspheres for Radioembolization Therapy Treatment Planning: A Prospective Single-Arm Clinical Trial

Authors

Nima Kokabi
Linzi A Webster
Mohammad Elsayed
Jeffrey M Switchenko
Bernard Chen
David Brandon
James Galt
Ila Sethi
Mircea Cristescu
S Cheenu Kappadath
David M Schuster

Publication Date

12-1-2022

Journal

Journal of Vascular and Interventional Radiology

Abstract

PURPOSE: To compare the accuracy and safety of 0.56 GBq resin yttrium-90 (

MATERIALS AND METHODS: This prospective single-arm clinical trial (Clinicaltrials.gov: NCT04172714) recruited patients with HCC. Patients underwent same-day mapping with MAA and scout

RESULTS: Thirty patients were treated using 19 segmental and 14 nonsegmental (ie, 2 contiguous segments or nonsegmental) therapies. MAA had weak LSF, moderate TNR, and moderate TD linear correlation with Rx

CONCLUSIONS: Compared with MAA, scout

Keywords

Humans, Carcinoma, Hepatocellular, Microspheres, Technetium Tc 99m Aggregated Albumin, Tissue Distribution, Prospective Studies, Liver Neoplasms, Embolization, Therapeutic, Yttrium Radioisotopes, Tomography, Emission-Computed, Single-Photon, Retrospective Studies

DOI

10.1016/j.jvir.2022.08.027

PMID

36075560

PMCID

PMC9834905

PubMedCentral® Posted Date

January 2023

PubMedCentral® Full Text Version

Author MSS

Published Open-Access

yes