Faculty, Staff and Student Publications
Publication Date
12-10-2024
Journal
Journal of Clinical Investigation
DOI
10.1172/JCI189625
PMID
39656547
PMCID
PMC11735086
PubMedCentral® Posted Date
12-10-2024
PubMedCentral® Full Text Version
Post-print
Abstract
Victor Ambros at the University of Massachusetts Medical School and Gary Ruvkun at Harvard University were awarded the 2024 Nobel Prize in Medicine and Physiology for the discovery of microRNAs. This “groundbreaking discovery revealed a completely new principle of gene regulation that turned out to be essential for multicellular organisms, including humans” (1). This is a well-deserved and highly anticipated recognition for a seminal discovery published 31 years ago in back-to-back Cell publications (2, 3). This landmark finding changed the way we understand gene expression regulation among most multicellular organisms (4) and had a huge impact in deciphering the mechanisms of many diseases.
Published Open-Access
yes
Recommended Citation
Rares Drula and George A Calin, "MicroRNAs: Where Brilliance, Perseverance, and Ambition Converged" (2024). Faculty, Staff and Student Publications. 4279.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/4279
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