GPR56: GPCR as a Guardian Against Ferroptosis

Authors

Yuelong Yan
Li Zhuang
Boyi Gan

Language

English

Publication Date

11-5-2024

Journal

Cell Metabolism

DOI

10.1016/j.cmet.2024.08.011

PMID

39504935

Abstract

Transmembrane receptor proteins are proficient in sensing external signals and initiating downstream pathways to control cell survival. Lin et al. demonstrated that GPR56, a G-protein-coupled receptor, can be activated by its agonist to suppress ferroptosis-a form of cell death-and effectively mitigate ferroptosis-associated liver damage.

Keywords

Ferroptosis, Receptors, G-Protein-Coupled, Humans, Animals

Published Open-Access

yes

Recommended Citation

Yuelong Yan, Li Zhuang, and Boyi Gan, "GPR56: GPCR as a Guardian Against Ferroptosis" (2024). Faculty, Staff and Student Publications. 5683.
https://digitalcommons.library.tmc.edu/uthgsbs_docs/5683