Baylor College of Medicine is a health sciences university that creates knowledge and applies science and discoveries to further education, healthcare and community service locally and globally. Learn more about our mission, vision and values.

Manuscripts submitted for publication (preprints), peer-reviewed pre-publication articles (postprints), and published articles from the faculty of Baylor College of Medicine are posted here with additional links to supplemental data.

Ranked 20th in the nation, and first in Texas since 2006 for obtaining National Institutes of Health (NIH) funding, Baylor College of Medicine received $687 million in total funding from 2,792 sponsored project awards in fiscal year 2023. Baylor operates more than 90 research and patient-care centers and units. BCM also operates more than 27 Advanced Technology Core Laboratories that provide services for studies in areas like metabolomics, proteomics, pathology, and genomics.

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Submissions from 2022

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Patients with Lung Cancer of Different Racial Backgrounds Harbor Distinct Immune Cell Profiles, Yitian Xu, Licheng Zhang, Jose Thaiparambil, et al.

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Role of Drosophila in Human Disease Research 2.0, Masamitsu Yamaguchi and Shinya Yamamoto

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Functional Studies of Genetic Variants Associated with Human Diseases in Notch Signaling-Related Genes Using Drosophila, Sheng-An Yang, Jose L Salazar, David Li-Kroeger, et al.

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Design, Usability, and Acceptability of a Needs-Based, Automated Dashboard to Provide Individualized Patient-Care Data to Pediatric Residents, Julia K W Yarahuan, Huay-Ying Lo, Lanessa Bass, et al.

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In Alzheimer-Prone Brain Regions, Metabolism and Risk-Gene Expression Are Strongly Correlated, Fengdan Ye, Quentin Funk, Elijah Rockers, et al.

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An Estrogen-Sensitive Hypothalamus-Midbrain Neural Circuit Controls Thermogenesis and Physical Activity, Hui Ye, Bing Feng, Chunmei Wang, et al.

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Single Cell RNA Sequencing of the Adult Drosophila Eye Reveals Distinct Clusters and Novel Marker Genes for All Major Cell Types, Kelvin Yeung, Komal Kumar Bollepogu Raja, Yoon-Kyung Shim, et al.

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Emergency Department Antimicrobial Use in a Low-Resource Setting: Results From a Retrospective Observational Study at a Referral Hospital in Liberia, Sojung Yi, Anu Ramachandran, Lane Epps, et al.

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Association of PD-L1 Expression and Other Variables With Benefit From Immune Checkpoint Inhibition in Advanced Gastroesophageal Cancer: Systematic Review and Meta-analysis of 17 Phase 3 Randomized Clinical Trials, Harry H Yoon, Zhaohui Jin, Oudom Kour, et al.

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Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer, Adelaide Young, Wen Bu, Weiyu Jiang, et al.

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RSPO2 and RANKL Signal Through LGR4 To Regulate Osteoclastic Premetastatic Niche Formation and Bone Metastasis, Zhiying Yue, Xin Niu, Zengjin Yuan, et al.

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Retinoic Acid Receptor Activation Reduces Metastatic Prostate Cancer Bone Lesions by Blocking the Endothelial-to-Osteoblast Transition, Guoyu Yu, Paul G Corn, Pengfei Shen, et al.

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Skp2 Stabilizes Mcl-1 and Confers Radioresistance in Colorectal Cancer, Xinfang Yu, Li Zhou, Wenbin Liu, et al.

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Spatial Definition of the Human Progesterone Receptor-B Transcriptional Complex, Xinzhe Yu, Ping Yi, Anil K Panigrahi, et al.

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ERK Inhibitor Ulixertinib Inhibits High-Risk Neuroblastoma Growth In Vitro and In Vivo, Yang Yu, Yanling Zhao, Jongmin Choi, et al.

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New, Potent, Small Molecule Agonists of Tyrosine Kinase Receptors Attenuate Dry Eye Disease, Zhiyuan Yu, Shaon Joy, Tianxiong Mi, et al.

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Cathepsin S Is a Novel Target for Age-Related Dry Eye, Zhiyuan Yu, Jinmiao Li, Gowthaman Govindarajan, et al.

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Assessment for Deeper Understanding using Concept Maps: Lessons Learned from Flipped Teaching of Pharmacology, Munder Zagaar and Weichao Chen

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cGAS-Sting Activation Contributes to Podocyte Injury in Diabetic Kidney Disease, Nan Zang, Chen Cui, Xinghong Guo, et al.

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Parental Mosaicism for Apparent De Novo Genetic Variants: Scope, Detection, and Counseling Challenges, Roni Zemet, Ignatia B Van den Veyver, and Paweł Stankiewicz

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PPM1D in Solid and Hematologic Malignancies: Friend and Foe?, Linda Zhang, Joanne I Hsu, and Margaret A Goodell

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PPM1D in Solid and Hematologic Malignancies: Friend and Foe?, Linda Zhang, Joanne I Hsu, and Margaret A Goodell

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A Large-Scale Genome-Wide Gene-Gene Interaction Study of Lung Cancer Susceptibility in Europeans With a Trans-Ethnic Validation in Asians, Ruyang Zhang, Sipeng Shen, Yongyue Wei, et al.

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Spectral Clustering of Single-Cell Multi-Omics Data on Multilayer Graphs, Shuyi Zhang, Jacob R Leistico, Raymond J Cho, et al.

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Gene Therapy Knockdown of Hippo Signaling Resolves Arrhythmic Events in Pigs After Myocardial Infarction, Sui Zhang, Shijie Liu, John P Leach, et al.