Open-access, full-text copies of The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.

Older GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.

Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.

Follow


Theses/Dissertations from 2014

PDF

TARGETING THE MDM2-P53 AXIS FOR THE TREATMENT OF DEDIFFERENTIATED LIPOSARCOMA, Katelynn Bill

PDF

Targeting the Redox System to Overcome Mechanisms of Drug Resistance in Chronic Lymphocytic Leukemia, Marcia A. Ogasawara

PDF

TETHERED IL-15 TO AUGMENT THE THERAPEUTIC POTENTIAL OF T CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTOR: MAINTAINING MEMORY POTENTIAL, PERSISTENCE, AND ANTITUMOR ACTIVITY, Lenka Hurton

PDF

THE APICAL POLARITY COMPLEX PROTEIN, PALS1, REGULATES CELL FATE IN THE DEVELOPMENT OF CEREBELLUM AND NEOCORTEX, JUN YOUNG PARK

PDF

THE ASSOCIATION BETWEEN THE IL-1 PATHWAY, Isaac C. Wun

PDF

THE EPIGENETICS OF SMALL CELL PROSTATE CANCER, Brittany N. Kleb

PDF

The KRas/MAPK Pathway and Ligand Independent Activation of ERα: Implications for the Treatment of Endometrial Cancer, Kari Ring

PDF

THE NOVEL UPSTREAM REGULATOR OF FBXW7, JI-HYUN SHIN

PDF

THE ONCOGENIC MAP KINASE SIGNALING PATHWAY MODULATES MHC-I SURFACE EXPRESSION IN MELANOMA, Sherille Denae Bradley

PDF

The regulation of microRNA biogenesis by ribosome-interacting proteins, Brian Pickering

PDF

THE ROLE OF DUAL SPECIFICITY PHOSPHATASE -11 IN INNATE AND ADAPTIVE IMMUNE RESPONSES, Kalyan Chakravarthy Nallaparaju

PDF

THE ROLE OF GLUTAMINE AND MEVALONATE PATHWAY IN AFFECTING THE STEMNESS AND VIABILITY OF GLIOBLASTOMA STEM CELLS, Naima Hammoudi

PDF

The Role of MIR-34a in Inhibition of Prostate Tumor Growth in the bone and Induction of Autophagy, Sanchaika Gaur

PDF

THE ROLE OF THE C5A RECEPTOR IN HOST DEFENSE AGAINST LISTERIA MONOCYTOGENES, Daniel Calame

PDF

THE ROLE OF TRAF6 PHOSPHORYLATION IN Src/TRAF6-MEDIATED IKK, JNK, Akt ACTIVATION AND TUMORIGENESIS, Yun Seong Jeong

PDF

TYROSINE 370 PHOSPHORYLATION OF ATM POSITIVELY REGULATES DNA DAMAGE RESPONSE, Hong-Jen Lee

PDF

USE OF POSITRON EMISSION TOMOGRAPHY FOR PROTON THERAPY VERIFICATION, Jongmin Cho

PDF

Utilizing Haplotypes for Sensitive SNP Array-based Discovery of Somatic Chromosomal Mutations, Selina M. Vattathil

PDF

Volumetric scintillation dosimetry for scanned proton beams, Daniel G. Robertson

Theses/Dissertations from 2013

PDF

Acceleration of the PanIN Development in Mice Expressing Oncogenic K-Ras Due to a High Fat Diet, Bincy Philip

PDF

A Genomic Approach to Identify The Notch Pathway as a Putative Tumor Suppressor in Endometrial Cancer, Rajshi Gandhi

PDF

Altered ovarian cancer metabolism increases neuronal n-acetylaspartate to promote tumor growth, Behrouz Zand

PDF

AN ASSESSMENT OF KNOWLEDGE AND ATTITUDES OF GENETIC COUNSELING SERVICES IN U.S. HTCs, Brad Rolf; Deborah Brown; Miguel Escobar; Syed Hashmi M.D., Ph.D; Aroub Ayham Khleif; Sarah Noblin; and Marianna Raia

PDF

AN EVALUATION OF THE CONSISTENCY OF IMRT PATIENT-SPECIFIC QA TECHNIQUES, Elizabeth M. McKenzie

PDF

A NOVEL CARDIAC FUNCTION OF SUMO2/3 AND SENP5 DEPENDENT PATHWAY AND ITS PHYSIOLOGICAL IMPACT ON CONGESTIVE CARDIOMYOPATHY, Eun Young Kim

PDF

A Novel Mechanism of Skin Tumor Promotion Involving Interferon-gamma (IFNγ)/Signal Transducer and Activator of Transcription-1 (Stat1) Signaling in Epidermis, Ronald Bozeman

PDF

ATTITUDES AND PRACTICES OF GENETIC COUNSELORS IN PROVIDING PREDICTIVE TESTING TO MINORS AT RISK FOR LI-FRAUMENI SYNDROME, Allison Copeland

PDF

ATTITUDES TOWARD AND UTILIZATION OF NON-INVASIVE PRENATAL TESTING FOR CHROMOSOME ANEUPLOIDY AMONG OB/GYNS, Jessica Davis

PDF

BASIS FOR TARGETING MET ACTIVATION MEDIATED RESISTANCE TO PI3K INHIBITION IN BREAST CANCER, Ana M. Gonzalez-Angulo

PDF

BAYESIAN STATISTICAL METHODS IN GENE-ENVIRONMENT AND GENE-GENE INTERACTION STUDIES, Changlu Liu

PDF

Behavioral responses to methylphenidate: correlations with neuronal activity in the caudate nucleus, Catherine M. Claussen

PDF

CHARACTERIZATION OF DIFFERENTIATION AND PROGNOSTIC BIOMARKERS ON CD8+ TUMOR-INFILTRATING LYMPHOCYTES IN METASTATIC MELANOMA, Richard C. Wu

PDF

Characterization of Jak, STAT, and Src interactions in Head and Neck Squamous Cell Carcinoma, Reshma Jaseja and Reshma Jaseja

PDF

CHARACTERIZATION OF OSLDS FOR USE IN SMALL FIELD PHOTON BEAM DOSIMETRY, Christopher Pham

PDF

CHARACTERIZATION OF TCL1-Tg:P53-/- MICE THAT RESEMBLE HUMAN CHRONIC LYMPHOCYTIC LEUKEMIA WITH 17P-DELETION, Jinyun Liu

PDF

Characterization of the RNA binding and RNA degrading subunits of the eukaryotic exosome, Borislava Tsanova

PDF

CHARACTERIZATION OF THE ROLE OF CARMA3 IN ENDOPLASMIC RETICULUM STRESS-INDUCED NF-κB ACTIVATION, Zhicheng Zhou Mr

PDF

CHARACTERIZATION OF THE ROLE(S) OF ENV PROTEIN OF HUMAN ENDOGENOUS RETROVIRUS-K IN MULTIPLE HUMAN CANCERS, Ming Li

PDF

CHARACTERIZING THE EFFECT OF DASATINIB ON ANTI-TUMOR IMMUNE RESPONSE AND EXPLORING THE POTENTIAL OF COMBINING TARGETED THERAPY AND IMMUNOTHERAPY IN A C-KIT MUTANT MASTOCYTOMA MODEL, Yan Yang

PDF

C-JUN N-TERMINAL KINASES REGULATE ADENOVIRUS-MEDIATED AUTOPHAGY AND ANTIGEN PRESENTATION, Sarah R. Klein

PDF

Comparison of Tumor Shrinkage and Cumulative Dose Distribution for Lung Cancers, Yi Pei Chen

PDF

CONFORMATIONAL DYNAMICS OF K-RAS AND H-RAS PROTEINS: IS THERE FUNCTIONAL SPECIFICITY AT THE CATALYTIC DOMAIN?, NANDINI RAMBAHAL

PDF

Correction of Cystic Fibrosis-specific Induced Pluripotent Stem Cells, Jacquelin Hanh Bui

PDF

c-REL is a Transcriptional Target of Mesoderm Inducer in Xenopus Like 1 (MIXL1), Aaron C. Raymond

PDF

CXCR2 EXPRESSION IN TUMOR CELLS IS A POOR PROGNOSTIC FACTOR AND PROMOTES INVASION AND METASTASIS IN LUNG ADENOCARCINOMA, Erminia Massarelli

PDF

Delayed Thrombus Resolution and Fibroproliferative Vascular Wound Healing From Deficiency of Type III Collagen: a Paradoxical Mechanism for Tissue Fragility, Amy J. Reid

PDF

Design, Synthesis and Development of Transporter Targeting Agents for Image-guided Therapy and Drug Delivery, Ning Tsao

PDF

DEVELOPMENTAL AND MOLECULAR FUNCTIONS OF PLAKOPHILIN-3, William A. Munoz

PDF

Development and Characterization of an in vitro Four-species Anaerobic Dental Biofilm Model, Fernando Andrade

PDF

Development and implementation of a dynamic heterogeneous proton equivalent anthropomorphic thorax phantom for the assessment of scanned proton beam therapy, James L. Neihart

PDF

Development of HIF-1α/HIF-1β heterodimerization inhibitors using a novel bioluminescence reporter assay system for in vitro high throughput screening and in vivo imaging, Yun-Chen Chiang

PDF

DEVELOPMENT OF NOVEL METHODS TO MINIMIZE THE IMPACT OF SEQUENCING ERRORS IN THE NEXT-GENERATION SEQUENCING DATA ANALYSIS, Xiaofeng Zheng

PDF

Evaluating the Utility of Clinical Criteria for the Identification of Lynch Syndrome among Endometrial Cancer Patients, Amanda S. Bruegl

PDF

Evaluation of PRESAGE® dosimeters for brachytherapy sources and the 3D dosimetry and characterization of the new AgX100 125I seed model, Olivia Huang

PDF

EZH2 T416 Phosphorylation Enhances Breast Cancer Tumorigenesis, Adam M. LaBaff and Adam M. LaBaff

PDF

Galectin-3 Enhances the Malignant Melanoma Phenotype by Regulating Autotaxin, Russell R. Braeuer

PDF

GENOME-WIDE PROFILING UNVEILS CRITICIAL FUNCTIONS OF p53 IN HUMAN EMBRYONIC STEM CELLS, Kadir C. Akdemir

PDF

Improving Cervical Cancer Nodal Boost Radiation Therapy by Quantifying Uncertainties and Exploring Advanced Radiation Therapy Modalities, Zhiqian Yu

PDF

Induction of synthetic lethality in mutant KRAS cells for non-small cell lung cancers chemoprevention and therapy, Shaoyi Huang

PDF

Inflammatory Breast Cancer: The Immune Perspective, Evan N. Cohen

PDF

INTEGRATIVE BIOMARKER IDENTIFICATION AND CLASSIFICATION USING HIGH THROUGHPUT ASSAYS, Pan Tong

PDF

INTERACTION BETWEEN BRK AND HER2 IN BREAST CANCER, Midan Ai

PDF

INTERACTION OF BACILLUS ANTHRACIS EXOSPORIUM PROTEIN BCLA WITH COMPLEMENT FACTOR H AND SPORE PERSISTENCE IN THE LUNG, Sarah A. Jenkins

PDF

INTRODUCING A NOVEL METHOD FOR GENETIC ANALYSIS OF AUTISM SPECTRUM DISORDER, sepideh nouri

PDF

INVESTIGATING APOPTOSIS PATHWAY IN CHRONIC LYMPHOCYTIC LEUKEMIA: STROMAL INFLUENCE AND THERAPEUTIC ACTIVATION, Viralkumar M. Patel

PDF

INVESTIGATING THE ROLES OF THE p63 ISOFORMS IN THE MICRORNA BIOGENESIS PATHWAY, Deepavali Chakravarti

PDF

Investigation of Respiratory Motion Management Techniques for Proton and Photon Radiotherapy of Lung Cancer, Jason E. Matney

PDF

Knowledge and Expectations of Support People in Prenatal Genetic Counseling Sessions, Michelle A. McDougle

PDF

Ligand-Directed AAVP to Deliver a Therapeutic Transgene to Neuroendocrine Tumors of the Pancreas, Tracey L. Smith

PDF

Mechanisms Underlying the Heterogeneous Sensitivities of Cancer Cells to Proteasome Inhibitors, Matthew C. White

PDF

Mismatch Repair Deficient Tumors Lacking Known Sporadic Causes: Are They All Due to Lynch Syndrome?, Katherine M. Dempsey

PDF

MOLECULAR AND GENOMIC BASED INSIGHTS INTO THE EVOLUTION OF ENTEROCOCCUS FAECIUM FROM COMMENSAL TO HOSPITAL-ADAPTED PATHOGEN, Jessica R. Galloway-Pena

PDF

Molecular Mechanisms of Vascular Disease in Patients with Rare Variants in MYH11, Callie Kwartler

PDF

MTORC1 SIGNALING IN MEMORY FORMATION AND DYSFUNCTION, Natalia S. Rozas de O'Laughlin

PDF

Network Dynamics of Visual Naming, Christopher R. Conner

PDF

NEURAL CORRELATES OF AUDIOVISUAL SPEECH PERCEPTION IN APHASIA AND HEALTHY AGING, Sarah H. Baum

PDF

Novel Functions of Cetuximab in EGFR-targeted Therapy: Radiosensitization, Glycolysis Inhibition, and Cellular Redox Status Regulation, Haiquan Lu

PDF

Novel Imaging-Based Techniques Reveal a Role for PD-1/PD-L1 in Tumor Immune Surveillance in the Lung, Todd Bartkowiak

PDF

NOVEL INDUCERS OF GLIOTOXIN PRODUCTION IN ASPERGILLUS FUMIGATUS, Taylor J. Schoberle

PDF

NOVEL THERAPEUTIC TARGETS IDENTIFIED BY HIGH-THROUGHPUT TECHNOLOGIES FOR TRIPLE-NEGATIVE BREAST CANCER, Christine Shiang

PDF

OXIDATIVE STRESS BASED STRATEGIES FOR ENHANCING THE EFFICACY OF HISTONE DEACETYLASE INHIBITORS (HDACi), Nilsa Rivera-Del Valle

PDF

PIM KINASE INHIBITION: SINGLE AGENT AND COMBINATION APPROACHES IN B-CELL LYMPHOMA, Qingshan Yang

PDF

PRKCa: Identification of a Novel Downstream Target of WT1, Devin Jones

PDF

Radiogenic Second Cancer Risk Differences in Female Hodgkin Lymphoma Patients Treated with Proton versus Photon Radiotherapies, Kenneth L. Homann

PDF

Radiomics of NSCLC: Quantitative CT Image Feature Characterization and Tumor Shrinkage Prediction, Luke Hunter

PDF

Renal Cryoablation: Investigation of Periprocedural Visualization Tools and Treatment Response Quantification, Katherine L. Dextraze

PDF

RNA-SEQUENCING APPLICATIONS: GENE EXPRESSION QUANTIFICATION AND METHYLATOR PHENOTYPE IDENTIFICATION, Guoshuai Cai

PDF

ROLE OF MIR-19A RELEASED BY INFLAMMATORY BREAST CANCER CELLS IN THE REGULATION OF DENDRITIC CELL FUNCTIONS: IN VITRO MODEL OF CROSSTALK IN THE TUMOR MICROENVIRONMENT OF INFLAMMATORY BREAST CANCER, Simone Anfossi

PDF

Role of Neurogranin in the regulation of calcium binding to Calmodulin, Anuja Chandrasekar

PDF

Scanned Ion Beam Therapy for Thoracic Tumors, John Gordon Eley

PDF

STIMULATION THROUGH TLR4 INCREASES FVIII INHIBITOR FORMATION IN A MOUSE MODEL OF HEMOPHILIA A, Claire K. Holley

PDF

Structure-function analysis of human Integrator subunit-4, Anupama Sataluri

PDF

STUDYING AGGREGATE FORMATION BY AMYOTROPHIC LATERAL SCLEROSIS-ASSOCIATED MUTANT SOD1 PROTEIN IN DROSOPHILA MODEL, Michael McCarthy

PDF

Targeted Deletion Of Functionally Validated Enhancers Defines Their Role in Mouse Limb Development, Mark J. Nolte

PDF

Targeting Histone deacetylases (HDAC) for the treatment of soft tissue sarcoma, Gonzalo Lopez

PDF

T-CELL TREATMENTS FOR SOLID AND HEMATOLOGICAL TUMORS, Drew C. Deniger

PDF

THE IMPACT OF FAMILY HISTORY ON MEDULLARY THYROID CANCER IN MEN2A PATIENTS, Nicole D. Mohrbacher

PDF

The Influence of Immunization Route on the Adjuvant Effect of alpha-Galactosylceramide, Ameerah M. Wishahy

PDF

THE MOLECULAR INTERACTION BETWEEN TYPE II DIABETES AND ALZHEIMER’S DISEASE THROUGH CROSS-SEEDING OF PROTEIN MISFOLDING, George A. Edwards III

PDF

THE NATURAL AND ORTHOGONAL INTERACTION (NOIA) MODELS FOR QUANTITATIVE TRAITS (QTs) AND COMPLEX DISEASES, Feifei Xiao