Open-access, full-text copies of The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.
Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.
Older GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.
Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.
Theses/Dissertations from 2014
TARGETING THE MDM2-P53 AXIS FOR THE TREATMENT OF DEDIFFERENTIATED LIPOSARCOMA, Katelynn Bill
Targeting the Redox System to Overcome Mechanisms of Drug Resistance in Chronic Lymphocytic Leukemia, Marcia A. Ogasawara
THE APICAL POLARITY COMPLEX PROTEIN, PALS1, REGULATES CELL FATE IN THE DEVELOPMENT OF CEREBELLUM AND NEOCORTEX, JUN YOUNG PARK
THE ASSOCIATION BETWEEN THE IL-1 PATHWAY, Isaac C. Wun
THE EPIGENETICS OF SMALL CELL PROSTATE CANCER, Brittany N. Kleb
THE NOVEL UPSTREAM REGULATOR OF FBXW7, JI-HYUN SHIN
THE ONCOGENIC MAP KINASE SIGNALING PATHWAY MODULATES MHC-I SURFACE EXPRESSION IN MELANOMA, Sherille Denae Bradley
The regulation of microRNA biogenesis by ribosome-interacting proteins, Brian Pickering
THE ROLE OF DUAL SPECIFICITY PHOSPHATASE -11 IN INNATE AND ADAPTIVE IMMUNE RESPONSES, Kalyan Chakravarthy Nallaparaju
THE ROLE OF GLUTAMINE AND MEVALONATE PATHWAY IN AFFECTING THE STEMNESS AND VIABILITY OF GLIOBLASTOMA STEM CELLS, Naima Hammoudi
The Role of MIR-34a in Inhibition of Prostate Tumor Growth in the bone and Induction of Autophagy, Sanchaika Gaur
THE ROLE OF THE C5A RECEPTOR IN HOST DEFENSE AGAINST LISTERIA MONOCYTOGENES, Daniel Calame
THE ROLE OF TRAF6 PHOSPHORYLATION IN Src/TRAF6-MEDIATED IKK, JNK, Akt ACTIVATION AND TUMORIGENESIS, Yun Seong Jeong
TYROSINE 370 PHOSPHORYLATION OF ATM POSITIVELY REGULATES DNA DAMAGE RESPONSE, Hong-Jen Lee
USE OF POSITRON EMISSION TOMOGRAPHY FOR PROTON THERAPY VERIFICATION, Jongmin Cho
Utilizing Haplotypes for Sensitive SNP Array-based Discovery of Somatic Chromosomal Mutations, Selina M. Vattathil
Volumetric scintillation dosimetry for scanned proton beams, Daniel G. Robertson
Theses/Dissertations from 2013
Acceleration of the PanIN Development in Mice Expressing Oncogenic K-Ras Due to a High Fat Diet, Bincy Philip
A Genomic Approach to Identify The Notch Pathway as a Putative Tumor Suppressor in Endometrial Cancer, Rajshi Gandhi
Altered ovarian cancer metabolism increases neuronal n-acetylaspartate to promote tumor growth, Behrouz Zand
AN ASSESSMENT OF KNOWLEDGE AND ATTITUDES OF GENETIC COUNSELING SERVICES IN U.S. HTCs, Brad Rolf; Deborah Brown; Miguel Escobar; Syed Hashmi M.D., Ph.D; Aroub Ayham Khleif; Sarah Noblin; and Marianna Raia
AN EVALUATION OF THE CONSISTENCY OF IMRT PATIENT-SPECIFIC QA TECHNIQUES, Elizabeth M. McKenzie
A NOVEL CARDIAC FUNCTION OF SUMO2/3 AND SENP5 DEPENDENT PATHWAY AND ITS PHYSIOLOGICAL IMPACT ON CONGESTIVE CARDIOMYOPATHY, Eun Young Kim
ATTITUDES AND PRACTICES OF GENETIC COUNSELORS IN PROVIDING PREDICTIVE TESTING TO MINORS AT RISK FOR LI-FRAUMENI SYNDROME, Allison Copeland
ATTITUDES TOWARD AND UTILIZATION OF NON-INVASIVE PRENATAL TESTING FOR CHROMOSOME ANEUPLOIDY AMONG OB/GYNS, Jessica Davis
BASIS FOR TARGETING MET ACTIVATION MEDIATED RESISTANCE TO PI3K INHIBITION IN BREAST CANCER, Ana M. Gonzalez-Angulo
BAYESIAN STATISTICAL METHODS IN GENE-ENVIRONMENT AND GENE-GENE INTERACTION STUDIES, Changlu Liu
Behavioral responses to methylphenidate: correlations with neuronal activity in the caudate nucleus, Catherine M. Claussen
CHARACTERIZATION OF DIFFERENTIATION AND PROGNOSTIC BIOMARKERS ON CD8+ TUMOR-INFILTRATING LYMPHOCYTES IN METASTATIC MELANOMA, Richard C. Wu
Characterization of Jak, STAT, and Src interactions in Head and Neck Squamous Cell Carcinoma, Reshma Jaseja and Reshma Jaseja
CHARACTERIZATION OF OSLDS FOR USE IN SMALL FIELD PHOTON BEAM DOSIMETRY, Christopher Pham
CHARACTERIZATION OF TCL1-Tg:P53-/- MICE THAT RESEMBLE HUMAN CHRONIC LYMPHOCYTIC LEUKEMIA WITH 17P-DELETION, Jinyun Liu
Characterization of the RNA binding and RNA degrading subunits of the eukaryotic exosome, Borislava Tsanova
CHARACTERIZATION OF THE ROLE OF CARMA3 IN ENDOPLASMIC RETICULUM STRESS-INDUCED NF-κB ACTIVATION, Zhicheng Zhou Mr
C-JUN N-TERMINAL KINASES REGULATE ADENOVIRUS-MEDIATED AUTOPHAGY AND ANTIGEN PRESENTATION, Sarah R. Klein
Comparison of Tumor Shrinkage and Cumulative Dose Distribution for Lung Cancers, Yi Pei Chen
CONFORMATIONAL DYNAMICS OF K-RAS AND H-RAS PROTEINS: IS THERE FUNCTIONAL SPECIFICITY AT THE CATALYTIC DOMAIN?, NANDINI RAMBAHAL
Correction of Cystic Fibrosis-specific Induced Pluripotent Stem Cells, Jacquelin Hanh Bui
c-REL is a Transcriptional Target of Mesoderm Inducer in Xenopus Like 1 (MIXL1), Aaron C. Raymond
CXCR2 EXPRESSION IN TUMOR CELLS IS A POOR PROGNOSTIC FACTOR AND PROMOTES INVASION AND METASTASIS IN LUNG ADENOCARCINOMA, Erminia Massarelli
DEVELOPMENTAL AND MOLECULAR FUNCTIONS OF PLAKOPHILIN-3, William A. Munoz
Development and Characterization of an in vitro Four-species Anaerobic Dental Biofilm Model, Fernando Andrade
Development and implementation of a dynamic heterogeneous proton equivalent anthropomorphic thorax phantom for the assessment of scanned proton beam therapy, James L. Neihart
DEVELOPMENT OF NOVEL METHODS TO MINIMIZE THE IMPACT OF SEQUENCING ERRORS IN THE NEXT-GENERATION SEQUENCING DATA ANALYSIS, Xiaofeng Zheng
Evaluating the Utility of Clinical Criteria for the Identification of Lynch Syndrome among Endometrial Cancer Patients, Amanda S. Bruegl
EZH2 T416 Phosphorylation Enhances Breast Cancer Tumorigenesis, Adam M. LaBaff and Adam M. LaBaff
Galectin-3 Enhances the Malignant Melanoma Phenotype by Regulating Autotaxin, Russell R. Braeuer
GENOME-WIDE PROFILING UNVEILS CRITICIAL FUNCTIONS OF p53 IN HUMAN EMBRYONIC STEM CELLS, Kadir C. Akdemir
Induction of synthetic lethality in mutant KRAS cells for non-small cell lung cancers chemoprevention and therapy, Shaoyi Huang
Inflammatory Breast Cancer: The Immune Perspective, Evan N. Cohen
INTEGRATIVE BIOMARKER IDENTIFICATION AND CLASSIFICATION USING HIGH THROUGHPUT ASSAYS, Pan Tong
INTERACTION BETWEEN BRK AND HER2 IN BREAST CANCER, Midan Ai
INTERACTION OF BACILLUS ANTHRACIS EXOSPORIUM PROTEIN BCLA WITH COMPLEMENT FACTOR H AND SPORE PERSISTENCE IN THE LUNG, Sarah A. Jenkins
INTRODUCING A NOVEL METHOD FOR GENETIC ANALYSIS OF AUTISM SPECTRUM DISORDER, sepideh nouri
INVESTIGATING APOPTOSIS PATHWAY IN CHRONIC LYMPHOCYTIC LEUKEMIA: STROMAL INFLUENCE AND THERAPEUTIC ACTIVATION, Viralkumar M. Patel
INVESTIGATING THE ROLES OF THE p63 ISOFORMS IN THE MICRORNA BIOGENESIS PATHWAY, Deepavali Chakravarti
Investigation of Respiratory Motion Management Techniques for Proton and Photon Radiotherapy of Lung Cancer, Jason E. Matney
Knowledge and Expectations of Support People in Prenatal Genetic Counseling Sessions, Michelle A. McDougle
Ligand-Directed AAVP to Deliver a Therapeutic Transgene to Neuroendocrine Tumors of the Pancreas, Tracey L. Smith
Mechanisms Underlying the Heterogeneous Sensitivities of Cancer Cells to Proteasome Inhibitors, Matthew C. White
Mismatch Repair Deficient Tumors Lacking Known Sporadic Causes: Are They All Due to Lynch Syndrome?, Katherine M. Dempsey
MOLECULAR AND GENOMIC BASED INSIGHTS INTO THE EVOLUTION OF ENTEROCOCCUS FAECIUM FROM COMMENSAL TO HOSPITAL-ADAPTED PATHOGEN, Jessica R. Galloway-Pena
Molecular Mechanisms of Vascular Disease in Patients with Rare Variants in MYH11, Callie Kwartler
MTORC1 SIGNALING IN MEMORY FORMATION AND DYSFUNCTION, Natalia S. Rozas de O'Laughlin
Network Dynamics of Visual Naming, Christopher R. Conner
NEURAL CORRELATES OF AUDIOVISUAL SPEECH PERCEPTION IN APHASIA AND HEALTHY AGING, Sarah H. Baum
Novel Imaging-Based Techniques Reveal a Role for PD-1/PD-L1 in Tumor Immune Surveillance in the Lung, Todd Bartkowiak
NOVEL INDUCERS OF GLIOTOXIN PRODUCTION IN ASPERGILLUS FUMIGATUS, Taylor J. Schoberle
NOVEL THERAPEUTIC TARGETS IDENTIFIED BY HIGH-THROUGHPUT TECHNOLOGIES FOR TRIPLE-NEGATIVE BREAST CANCER, Christine Shiang
OXIDATIVE STRESS BASED STRATEGIES FOR ENHANCING THE EFFICACY OF HISTONE DEACETYLASE INHIBITORS (HDACi), Nilsa Rivera-Del Valle
PIM KINASE INHIBITION: SINGLE AGENT AND COMBINATION APPROACHES IN B-CELL LYMPHOMA, Qingshan Yang
PRKCa: Identification of a Novel Downstream Target of WT1, Devin Jones
Radiogenic Second Cancer Risk Differences in Female Hodgkin Lymphoma Patients Treated with Proton versus Photon Radiotherapies, Kenneth L. Homann
Radiomics of NSCLC: Quantitative CT Image Feature Characterization and Tumor Shrinkage Prediction, Luke Hunter
Renal Cryoablation: Investigation of Periprocedural Visualization Tools and Treatment Response Quantification, Katherine L. Dextraze
RNA-SEQUENCING APPLICATIONS: GENE EXPRESSION QUANTIFICATION AND METHYLATOR PHENOTYPE IDENTIFICATION, Guoshuai Cai
Role of Neurogranin in the regulation of calcium binding to Calmodulin, Anuja Chandrasekar
Scanned Ion Beam Therapy for Thoracic Tumors, John Gordon Eley
STIMULATION THROUGH TLR4 INCREASES FVIII INHIBITOR FORMATION IN A MOUSE MODEL OF HEMOPHILIA A, Claire K. Holley
Structure-function analysis of human Integrator subunit-4, Anupama Sataluri
STUDYING AGGREGATE FORMATION BY AMYOTROPHIC LATERAL SCLEROSIS-ASSOCIATED MUTANT SOD1 PROTEIN IN DROSOPHILA MODEL, Michael McCarthy
Targeted Deletion Of Functionally Validated Enhancers Defines Their Role in Mouse Limb Development, Mark J. Nolte
Targeting Histone deacetylases (HDAC) for the treatment of soft tissue sarcoma, Gonzalo Lopez
T-CELL TREATMENTS FOR SOLID AND HEMATOLOGICAL TUMORS, Drew C. Deniger
THE IMPACT OF FAMILY HISTORY ON MEDULLARY THYROID CANCER IN MEN2A PATIENTS, Nicole D. Mohrbacher
The Influence of Immunization Route on the Adjuvant Effect of alpha-Galactosylceramide, Ameerah M. Wishahy
THE MOLECULAR INTERACTION BETWEEN TYPE II DIABETES AND ALZHEIMER’S DISEASE THROUGH CROSS-SEEDING OF PROTEIN MISFOLDING, George A. Edwards III
THE NATURAL AND ORTHOGONAL INTERACTION (NOIA) MODELS FOR QUANTITATIVE TRAITS (QTs) AND COMPLEX DISEASES, Feifei Xiao