Open-access, full-text copies of The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.

Older GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.

Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.

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Theses/Dissertations from 2011

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ROLE OF VITAMIN-D3 AND RETINOIC ACID IN A HUMAN THP-1 MACROPHAGE MODEL OF MYCOBACTERIUM TUBERCULOSIS INFECTION, Jaymie L. Estrella

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ROLES FOR BRAF KINASE ACTIVATING MUTATIONS IN MELANOMA: MICROENVIRONMENTAL IMMUNOSUPPRESSION, Jahan Khalili

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Significance of Increased Tissue Transglutaminase in Hormone Refractory Prostate Cancer, Amy L. Han

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STAT3 CONTROLS THE NEUTROPHIL MIGRATORY RESPONSE TO CXCR2 AND ITS LIGAND MIP-2 (CXCL2), Hoainam Nguyen-Jackson

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Stromal derived growth factor alpha (SDF-1α) induces the differentiation of bone marrow progenitor cells (BMCs) into pericytes by regulating platelet derived growth factor B (PDGF-B) transcription, Randala Hamdan

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STUDY OF REST AS A NEGATIVE REGULATOR OF P16INK4A, Monica B. Gireud

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SUMO-SPECIFIC PROTEASE 1 CONTROLS LYMPHOID DEVELOPMENT THROUGH REGULATION OF SUMOYLATION/ACETYLATION SWITCH IN STAT5, Thang Van Nguyen

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Targeted Multistage Delivery of Nanoparticles to the Bone Marrow, Aman Mann

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THE ASSOCIATION BETWEEN CANCER-RELATED-FATIGUE, RESPONSE TO FATIGUE TREATMENT, AND CYTOKINES AND THEIR RECEPTORS, IN PATIENTS WITH ADVANCED CANCER, Sriram Yennu

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THE CYTOPLASMIC TAIL OF MHC CLASS I MOLECULES PLAYS A CRITICAL ROLE IN DENDRITIC CELL-INDUCED T CELL IMMUNITY, Tania G. Rodriguez-Cruz

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The Development and Implementation of an Anthropomorphic Head Phantom for the Assessment of Proton Therapy Treatment Procedures, Paige A. Summers

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The Dissociation of Location and Object Working Memory using fMRI and MEG, Antony Passaro

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The effect of shoulder variation on IMRT and SmartArc for Head and Neck Cancer, Emily H. Neubauer

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THE EFFECTS OF CURCUMIN ON BODY COMPOSITION OF PATIENTS WITH ADVANCED PANCREATIC CANCER, Henrique A. Parsons MD

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THE EXPRESSION PROFILE OF A GWAS DETECTED GENE (NINJ2) IN THE BRAIN OF A MOUSE MODEL OF ISCHEMIC STROKE, Antonio Joel Tito Jr. and Antonio Joel Tito Jr.

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THE MECHANISM OF TUMORIGENESIS IN THE IMMORTALIZED HUMAN PANCREATIC CELL LINES: CELL CULTURE MODELS OF HUMAN PANCREATIC CANCER, Zhe Chang

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The Neural Substrates of Multisensory Speech Perception, Audrey R. Nath

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THE ROLE AND MECHANISM OF THE HOMEOBOX GENE DLX4 IN TRANSFORMING GROWTH FACTOR-B RESISTANCE IN CANCER, Bon Q. Trinh

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The Role of Acidic Fibroblast Growth Factor and Fibroblast Growth Factor Receptor 4 in High Grade Serous Carcinoma, Tarrik Zaid

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The Role of Cancer-Associated Fibroblasts in Lung Tumorigenesis, Jonathon D. Roybal

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The Role of Cell Sterilization in Population Based Studies of Radiogenic Second Cancers Following Radiation Therapy, Annelise Giebeler

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The Role of Cortisol in the Cycle of Violence, Joshua Leigh Gowin

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THE ROLE OF CYCLIN E IN PKC IOTA-DRIVEN EARLY OVARIAN TUMORIGENESIS, Angela Nanos-Webb

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THE ROLE OF E2F1 IN THE RESPONSE TO DNA DOUBLE STRAND BREAKS, Jie Chen

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The Role of IL-6 in Adenosine-Mediated Pulmonary Fibrosis, Mesias Pedroza

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THE ROLE OF RECEPTOR TYROSINE KINASE AXL IN PANCREATIC DUCTAL ADENOCARCINOMA AND ITS REGULATION BY HEMATOPOIETIC PROGENITOR KINASE 1, Xianzhou Song

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THE ROLE OF TAK1 IN PANCREATIC CANCER DEVELOPMENT, qianghua xia

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The Role of the Androgen Receptor Cofactor p44/WDR77 in Astrocyte Activation, Bryce H. Vincent

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TP53 as a Biomarker in Head and Neck Squamous Cell Carcinoma, Thomas J. Ow MD

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UNDERSTANDING NANOG'S ROLE IN CANCER BIOLOGY, Mark D. Badeaux

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Upregulation of Reactive Oxygen Species During the Retrovirus Life Cycle and Their Roles in a Mutant of Moloney Murine Leukemia Virus, ts1-Mediated Neurodegeneration, SOO JIN KIM

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Uptake And Metabolism Of 5’-AMP In The Erythrocyte Play Key Roles In The 5’-AMP Induced Model Of Deep Hypometabolism, Isadora Daniels

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ΔNp63 REGULATES A COMPLEX NETWORK OF TARGET GENES IN LIMB AND EPIDERMAL DEVELOPMENT, Min Soon Cho

Theses/Dissertations from 2010

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14-3-3SIGMA NEGATIVELY REGULATES THE STABILITY AND SUBCELLULAR LOCALIZATION OF COP1, Chun-Hui Su

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A BAYESIAN APPROACH TO DOSE-RESPONSE ASSESSMENT AND DRUG-DRUG INTERACTION ANALYSIS: APPLICATION TO IN VITRO STUDIES, Violeta G. Hennessey

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A METAGENOMIC STUDY OF THE TICK MIDGUT, Daniel T. Yuan

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AMPA RECEPTOR ALLOSTERISM: MEASUREMENT OF THE CONFORMATIONAL CHANGES IN THE LIGAND BINDING DOMAIN OF A FUNCTIONAL RECEPTOR, Jennifer Gonzalez-McGehee

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Analysis of Variation in Clubfoot Candidate Genes, Audrey R. Ester

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ANALYSIS OF β8 INTEGRIN IN NEUROGENESIS AND NEUROVASCULAR HOMEOSTASIS, Aaron K. Mobley

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Analyzing the Role of αvβ8 Integrin in Glioma-Induced Angiogenesis, Jeremy H. Tchaicha

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An assessment of obesity and hyperphagia in individuals with Smith-Magenis syndrome, Carrie A. Crain

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A NEW TUMOR SUPPRESSOR GENE CANDIDATE REGULATED BY THE NON-CODING RNA PCA3 IN HUMAN PROSTATE CANCER, Alessandro K. Lee

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AN IMPLANTABLE MOSFET DOSIMETER MODIFIED TO ACT AS A FIDUCIAL MARKER, Joseph S. Dick

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An Innovative Phase I Trial Design Allowing for the Identification of Multiple Potential Maximum Tolerated Doses with Combination Therapy of Targeted Agents, Sarina A. Piha-Paul

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Application of Signal Advance Technology to Electrophysiology, Chris M. Hymel

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A RANDOMIZED TRIAL OF BILEVEL POSITIVE AIRWAY PRESSURE DEVICE AND HIGH FLOW OXYGEN FOR PERSISTENT DYSPNEA IN, David Hui

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ARTEMIS INTERACTS WITH THE CUL4A UBIQUITIN E3 LIGASE COMPLEX AND REGULATES THE CELL CYCLE PROGRESSION, Yiyi Yan

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Attitudes of Parents at risk of inheriting Li-Fraumeni Syndrome towards predictive genetic testing in their minor-aged children., Leslie A. Newman

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BENCHMARKING AND IMPLEMENTATION OF A NEW INDEPENDENT MONTE CARLO DOSE CALCULATION QUALITY ASSURANCE AUDIT TOOL FOR CLINICAL TRIALS, Scott E. Davidson

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CELLULAR AND DEVELOPMENTAL FUNCTIONS OF THE XENOPUS ARVCF-CATENIN:KAZRIN COMPLEX, Kyucheol Cho

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Characterization and optimization of antigen-specific T cell responses during ex vivo expansion of melanoma tumor-infiltrating lymphocytes, yufeng li

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CHARACTERIZATION OF ALPHA-GALACTOSYLCERAMIDE AS A MUCOSAL ADJUVANT, Amy N. Courtney

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Characterization of Optically Stimulated Luminescent Detectors in Photon & Proton Beams for Use in Anthropomorphic Phantoms, James R. Kerns

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Characterization of the Agrobacterium tumefaciens VirB2 pilin of the VirB/D4 Type IV Secretion System, Jennifer Kerr

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CHARACTERIZING AND TREATING THE NEUROPATHOLOGY OF TUBEROUS SCLEROSIS COMPLEX IN THE MOUSE, Sharon W. Way

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CHARACTERIZING A NOVEL GENETIC LOCUS ASSOCIATED WITH FAMILIAL CO-OCCURRENCE OF THORACIC AORTIC ANEURYSMS AND INTRACRANIAL ANEURYSMS, Alexander H. Li

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CIP4 and Src in Promoting the Migration and Invasion of Breast Cancers, Christina S. Pichot

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Commissioning an Anthropomorphic Spine and Lung Phantom for Remote Dose Verification of Institutions Participating in RTOG 0631, Douglas F. Caruthers

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DAMAGE-INDUCED INFLAMMATION AND NOCICEPTIVE HYPERSENSITIVITY IN DROSOPHILA LARVAE, Daniel T. Babcock

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Defining the role of IL-15 trans-presentation by distinct cell-types during the development and homeostasis of Natural Killer and invariant Natural Killer T cells, Eliseo F. Castillo

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Delta like ligand 4 is a critical regulator of bone marrow cell differentiation into pericytes/vascular smooth muscle cells and is essential for the vasculogenesis that supports the growth of Ewing’s sarcoma, Keri L. Stewart

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Developmental Changes in the Structure and Composition of the Postsynaptic Density, Matthew T. Swulius

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DIRECT INPUTS TO OFF Α AND G9 GANGLION CELLS FROM AII AMACRINE CELLS IN RABBIT RETINA, Wei-Li Liu

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DOUBLE-STRAND BREAK REPAIR PATHWAYS IN DNA STRUCTURE-INDUCED GENETIC INSTABILITY, Diem T. Kha

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Dynamic Chemical Shift Imaging for Image-Guided Thermal Therapy, Brian A. Taylor

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Dynamic Remodeling of the Stressed Heart: Role of Protein Degradation Pathways, Deborah Vela

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E2F1 AND TUMOR SUPPRESSION: THE ROLE OF p21, miRNAS, AND THE DNA DAMAGE RESPONSE, Regina L. Weaks

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Effect of Acute Administration of Angiopoietin-1 in Experimental Traumatic Spinal Cord Injury: Magnetic Resonance Imaging and Neurobehavioral Studies, Chirag B. Patel

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Effects of Combined Bevacizumab and Paclitaxel on Tumor Interstitial Fluid Pressure in a Preclinical Breast Cancer Model, Ricardo Hugo Alvarez

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EFFICACY AND MECHANISM OF â-DEFENSIN2 FUSED ANTIGEN PROTEIN VACCINES, Hyun J. Park

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ELUCIDATING FUNCTIONAL ROLES FOR MYOGENIN IN ADULT SKELETAL MUSCLE METABOLISM, EXERCISE CAPACITY, AND REGENERATION, Jesse Flynn

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ELUCIDATING THE ROLE OF CD44 EXPRESSION ON MESENCHYMAL STEM CELLS WITHIN THE TUMOR MICROENVIRONMENT, Erika L. Spaeth

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AGROBACTERIUM VIRB10 CONTRIBUTIONS TO TYPE IV SUBSTRATE SECRETION, T-PILUS BIOGENESIS, AND OUTER MEMBRANE PORE FORMATION, Isaac Garza

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EVALUATION OF THE QUANTITATIVE ACCURACY OF A COMMERCIALLY-AVAILABLE POSITRON EMISSION MAMMOGRAPHY SCANNER, Adam Springer

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Eye Movement Measures of Cognitive Control in Children with Tourette Syndrome, Cameron B. Jeter

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Factors Associated with Early Versus Late Development of Breast and Ovarian Cancer in BRCA1 and BRCA2 Positive Women, Justine M. Cooper

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First Trimester Screening and its Impact on Uptake of Diagnostic Testing, Deanna Darnes

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GENETIC ANALYSIS OF THE FUNCTION OF THE DROSOPHILA DOUBLESEX-RELATED FACTOR dmrt93B, Diana O'Day

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GSK3 Mediates Signaling Upstream of Akt, Debra L. Smith

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Host-pathogen interactions of secreted and surface Staphylococcus aureus factors, Vanessa Vazquez

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Identification of the Causative Bacteria in Musculoskeletal Infections Using 16s rDNA - Denaturing Gradient Gel Electrophoresis Analysis, Karen Gomez

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IL-2 REGULATION OF IL-24 EXPRESSION LEADS TO GROWTH SUPPRESSION OF MELANOMA CELLS, Emily Jen

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Immune recognition of self nucleic acids driven by endogenous antimicrobial peptides: role in autoimmunity, Dipyaman Ganguly

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Implementation of an Anthropomorphic Phantom for the Evaluation of Proton Therapy Treatment Procedures, Ryan L. Grant

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IMPROVING QUANTITATIVE TREATMENT RESPONSE MONITORING WITH DEFORMABLE IMAGE REGISTRATION, Blake A. Cannon

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Influence of Anchoring on Miscarriage Risk Perception Associated with Amniocentesis, Regina A. Nuccio

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Inhibition of Deubiquitinase Activity and Ubiquitination of Jak2 Blocks Cytokine Signaling and Induces Tumor Cell Apoptosis, Vaibhav Kapuria

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LOSS OF GPRC5A ENHANCES SURVIVAL IN NORMAL AND MALIGNANT LUNG EPITHELIAL CELLS BY ELICITING PERSISTENT STAT3 ACTIVATION INDUCED BY AUTOCRINE LIF, Yulong Chen

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MCAM/MUC18 REGULATES MELANOMA PROGRESSION BY MODULATING THE EXPRESSION OF ID-1, Maya Zigler

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Measurement of the vascular input function in mice for DCE-MRI, Dustin K. Ragan

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MECHANISM-BASED STRATEGIES TO ENHANCE THE ACTIONS OF A, fabiola c. gomez

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MODELING SPORADIC TUMOR FORMATION DRIVEN BY TELOMERE DYSFUNCTION IN THE GASTROINTESTINAL TRACT, Suzanne S. Chan

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Molecular basis of Corynebacterium diphtheriae virulence and infection in the Caenorhabditis elegans model host, Melissa M. Broadway

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Myogenin modulates exercise endurance by altering skeletal muscle metabolism, james eric meadows

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NETWORK TOPOLOGY IN HUMAN PROTEIN INTERACTION DATA PREDICTS FUNCTIONAL ASSOCIATION, HUA LI

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NEW TARGET GENES FOR TUMOR SUPPRESSORS p53 AND p73 IN REGENERATING LIVER, Svitlana M. Kurinna

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NEW TOOLS FOR MONITORING GAMMA CAMERA UNIFORMITY, Brad K. Lofton

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NHERF1 – New Modifier of Colorectal Cancer Progression, Yuho Hayashi

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Osteopontin and cadherin 11 are novel mediators and drug targets for chronic lung diseases, Daniel J. Schneider

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PLASMACYTOID DENDRITIC CELLS SENSE SKIN INJURY AND PROMOTE WOUND HEALING THROUGH TYPE I INTERFERONS, Josh D. Gregorio