Open-access, full-text copies of The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.
Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.
Older GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.
Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.
Theses/Dissertations from 2015
GENETICS OF OBESITY IN STARR COUNTY, TEXAS MEXICAN AMERICANS, Heather M. Highland
Histone H3 K4 methylation regulates the Spindle Assembly Checkpoint through direct binding of multiple checkpoint components and Cdc20, Andria C. Schibler
IDENTIFICATION OF FAMILIAL WILMS TUMOR PREDISPOSITION GENES USING WHOLE GENOME SEQUENCING, Timothy B. Palculict
IDENTIFYING PROTEIN KINASE TBK1 AS A NOVEL INHIBITOR OF INTESTINAL TUMORIGENESIS, Amber L. Mathews
IGFBP2 POTENTIATES EGFR-STAT3 SIGNALING IN GLIOMA, Yingxuan Chua
IMPACT OF DIFFERENTIATION STATUS OF KIDNEY PROGENITORS IN WILMS TUMOR DEVELOPMENT, Le Huang
Improving Attenuation Correction in Hybrid Positron Emission Tomography, Hua Asher Ai
Induction of caspase-dependent death by proteasome targeted therapy in glioblastoma, Christa A. Manton
INFLUX AND EFFLUX OF ADENINE NUCLEOTIDES FROM ERYTHROCYTES REGULATE OXYGEN TRANSPORT AND SYSTEMIC METABOLISM, William G. O'Brien III
Investigating the Interaction of AURKA and UBE2C in Colorectal Cancer Cells, Apurva M. Hegde
Investigating the roles of p63 and p73 isoforms to therapeutically treat p53-altered cancers, Avinashnarayan Venkatanarayan
INVESTIGATION OF GENETIC ALTERATIONS IN EMT SUPPRESSOR, DEAR1, THROUGH PAN-CANCER ANALYSIS AND ULTRA-DEEP TARGETED SEQUENCING IN DUCTAL CARCINOMA IN SITU, Jacquelyn Reuther
INVESTIGATION OF THE ROLE OF THE SCAFFOLD PROTEIN SHC IN ERK SIGNALING, kin man suen
IN VIVO FUNCTIONAL SIGNIFICANCE OF CCAT2 LONG NON-CODING RNA IN MYELODYSPLASTIC SYNDROME, MAITRI Y. SHAH
IN VIVO SIGNIFICANCE OF THE MDM4 AND P73 INTERACTION DURING DEVELOPMENT AND TUMORIGENESIS, Mehrnoosh Tashakori
Isoform Selective Regulation of Adenylyl Cyclase by Small Molecule Inhibitors and Gbetagamma Protein, Cameron S. Brand
KNOWLEDGE AND SELF-ESTEEM IN INDIVIDUALS WITH NEUROFIBROMATOSIS TYPE 1 (NF1), Kayla Vaughn
MEASURING SINGLE CELL RESPONSES TO LAPATINIB IN A HETEROGENEOUS POPULATION, Preety Priya
MERLIN MEDIATED REGULATION OF HAIR FOLLICLE MORPHOGENESIS, Megan K. Fentress
Metabolic profiling of prions in the gastro-intestinal tract, Uffaf Khan
Methylation of EGFR by Arginine Methyltransferase PRMT1 Enhances EGFR Signaling and Cetuximab resistance, Hsin-Wei Liao
MICRORNA-200 REGULATES ECM-DEPENDENT β1-INTEGRIN/FAK SIGNALING AND CANCER CELL INVASION, Christin Ungewiss
Mobilization of Adipose Stromal Cells in Obesity and Cancer by SPARC and its Proteolytic Isoforms, Chieh Tseng
MOLECULAR REGULATION OF VASCULAR CALCIFICATION IN MURINE MODELS OF ATHEROSCLEROSIS, Shanshan Gao
MULTILEVEL DEREGULATION OF SURVIVAL MECHANISMS IN NPM-ALK+ T-CELL LYMPHOMA, Deeksha Vishwamitra
NEW INSIGHTS ON THE ROLE OF JMJD2A IN CANCER PROGRESSION, Yuan Gao
NFAT1 CONTRIBUTES TO MELANOMA TUMOR GROWTH AND METASTASIS BY REGULATING IL-8 AND MMP-3, Einav Shoshan
Normal Glycolytic Enzyme Activity is Critical for Hypoxia Inducible Factor-1a Activity and Provides Novel Targets for Inhibiting Tumor Growth, Geoffrey Grandjean PhD
Obstetrician and Gynecologist Utilization of the NIPT Expanded Testing Option, Sarah Mayes BA
Oxidative protein folding pathways in Gram-positive Actinobacteria, Melissa E. Robinson
PLASMACYTOID DENDRITIC CELL-MEDIATED HUMORAL AUTOIMMUNITY, Stephanie M. Dorta-Estremera Ph.D.
POST-TRANSLATIONAL REGULATION OF ZEB1 CONTRIBUTES TO TGFβ-MEDIATED EMT, Roxsan Manshouri
Prediction of Laser Ablation in Brain: Sensitivity, Calibration, and Validation, Samuel J. Fahrenholtz
PREVENTING THYMUS INVOLUTION IN K5.CYCLIN D1 TRANSGENIC MICE SUSTAINS THE NAÏVE T CELL COMPARTMENT WITH AGE, Michelle L. Bolner
Prophylactic Cranial Irradiation Reduces the Incidence of Brain Metastasis in a Mouse Model of Metastatic Breast Cancer, Daniel L. Smith
QUALITY ASSURANCE OF ADVANCED TREATMENT MODALITIES USING PRESAGE® DOSIMETERS, Ryan G. Lafratta
Quantification of IMRT severity scores for improvement of FMEA results, Jacqueline T. Faught
REDIRECTING T CELLS WITH CHIMERIC ANTIGEN RECEPTORS TO TARGET CD123+ LEUKEMIA, Radhika Thokala
REDUCTION OF DOSE CALCULATION ERRORS FOR PATIENTS WITH METAL IMPLANTS RECEIVING PHOTON RADIATION THERAPY, Jessie Huang-Vredevoogd
Regulation of Cell Adhesion by the FERM Proteins, PTPN14 and Merlin, Patty Dimarco Hewitt
REGULATION OF THE OXIDATIVE STRESS RESPONSE BY ARID1A, Suet Yan Kwan
REST REGULATORY CIRCUIT CONTROLS DISTINCT ONCOGENIC PROPERTIES OF GLIOBLASTOMA STEM CELLS THROUGH SPECIFIC MICRORNAs, Anantha L Marisetty
ROLE OF STAT3 IN HUMAN NK CELL FUNCTIONS, Prasad V. Phatarpekar
SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS: IN SUPPORT OF TRANSLATIONAL THERAPY, David Rushworth
SERUM OMENTIN AS A POTENTIAL BIOMARKER FOR COMPLEX ATYPICAL HYPERPLASIA AND ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA, Laura L. Holman MD
Spiritual Exploration in the Prenatal Genetic Counseling Session, Katelynn G. Sagaser
SRC HOMOLOGY 2 DOMAIN-CONTAINING 5’-INOSITOL PHOSPHATASE-2 (SHIP2) IS AN EFFECTOR OF LYMPHATIC DYSFUNCTION, Germaine D. Agollah
Structure and Composition of Postsynaptic Densities, Madeline Farley
SUNITINIB-INDUCED CARDIOTOXICITY EXPOSES MICROVASCULAR AND METABOLIC DERANGEMENTS IN THE FAILING HEART, Meredith R. Rodriguez
SYNTHETIC LETHALITY OF CDK INHIBITION AND DOXORUBICIN IN TRIPLE-NEGATIVE BREAST CANCER REQUIRES P53 INACTIVATION, Natalie A. Jabbour-Leung
TARGETED INHIBITION OF PI3K, MTOR, AND IGF1R FOR THE TREATMENT OF UNDIFFERENTIATED PLEOMORPHIC SARCOMA, Caitlin Denise May
Targeting An Ancient Retrovirus During Melanoma Using Adoptive T Cells Therapy, janani Krishnamurthy
Targeting oncogenic miRNAs with Small Molecules for Breast Cancer Therapy, Paloma del C. Monroig
Texas Physicians' Awareness and Utilization of Genetic Services, Callie L. Jenevein
THE EFFECT OF ACTIVATION INDUCED CYTIDINE DEAMINASE PHOSPHORYLATION AND HERPES VIRUS URACIL DNA GLYCOSYLASE ON ANTIBODY DIVERSIFICATION, Marc Macaluso
THE EFFECT OF ROOM ENVIRONMENT ON PATIENT EXPERIENCE IN A PRENATAL GENETIC COUNSELING SESSION, Elizabeth C. Baack
THERMAL ABLATION ALTERS THE TUMOR MICROENVIRONMENT ACTIVATING A ROBUST IMMUNE RESPONSE., Matthew T. Campbell M.D.
THE ROLE OF AUTOPHAGY IN THE SENSITIVITY OF OSTEOSARCOMA CELLS TO GEMCITABINE TREATMENT, Janice M. Santiago-O'Farrill
The role of DNA methylation and hydroxymethylation in smooth muscle cell phenotypic change during atherogenesis, jason Williams
The Structural Mechanism of Allosteric Modulation of the NMDA Receptor: A Balance of Tensions, Rita E. Sirrieh
THE TUMOR SUPPRESSOR NOTCH INHIBITS HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) TUMOR GROWTH AND PROGRESSION BY MODULATING PROTO-ONCOGENES AXL AND CTNNAL1 (α-CATULIN), Shhyam Moorthy and Shhyam Moorthy
TRIM28 INTERACTS WITH EZH2 TO REGULATE ITS ACTIVITY, Jing Li and Jing Li
TWO-COLOR FLUORESCENT ANALYSIS OF CONNEXIN 36 TURNOVER AND TRAFFICKING – RELATIONSHIP TO FUNCTIONAL PLASTICITY, Yanran Wang
UNDERSTANDING THE ROLE OF SUMOYLATION IN REGULATING LKB1 FUNCTION, Joan W. Ritho
YAP1 expression predicts sensitivity to dual AKT/P70S6K inhibition in ovarian and uterine malignancies, Rebecca A. Previs
Theses/Dissertations from 2014
ACTIVATING THE 4-1BB PATHWAY FOR THE EXPANSION OF TUMOR-INFILTRATING LYMPHOCYTES FOR ADOPTIVE T-CELL THERAPY FOR METASTATIC MELANOMA PATIENTS, Jessica Ann Chacon
ACTIVATING THE 4-1BB PATHWAY FOR THE EXPANSION OF TUMOR-INFILTRATING LYMPHOCYTES FOR ADOPTIVE T-CELL THERAPY FOR METASTATIC MELANOMA PATIENTS, Jessica Ann Chacon
Anchoring and Uptake of Non-Invasive Prenatal Testing in the First and Second Trimester, Amanda S. Hanson
ANGIOMOTIN IS A NOVEL CADHERIN-11 INTERACTING PROTEIN THAT MEDIATES MIGRATION IN PROSTATE CANCER CELLS, Angelica Ortiz
A NOVEL TABLET BASED SYSTEM TO MEASURE THE EFFECT OF SUBCONCUSSIVE BLOWS ON SENSORIMOTOR AND COGNITIVE FUNCTIONING, Stuart D. Red
Anti-GD2 Etoposide-Loaded Immunoliposomes for the Treatment of GD2 Positive Tumors, Brandon S. Brown
ANTI-INSULIN RESISTANCE TREATMENTS SUPPRESS HER2+ BREAST CANCER GROWTH VIA ALTERING METABOLISM, PING-CHIEH CHOU
Availability Of Dental Anomaly Phenotype In Individuals With Familial Adenomatous Polyposis, Andrea M. Lewis
Bioactivity and Cell-Mediated Targeting of Multistage Nanoporous Silicon Particles, Jonathan O. Martinez
BRIT1/MCPH1 MEDIATES THE DNA DAMAGE RESPONSE BY INDUCING P53 STABILITY AND PROMOTING ATR SIGNALING, Edward Wang
Cancer Diagnosis During Pregnancy: Evaluating the Challenges Faced by Oncologists, Shannon Kaye Mulligan
Cancers Associated with BRCA1 and BRCA2 Mutations Other Than Breast and Ovarian, Jacqueline Mersch
CAR-MODIFIED T CELLS CAPABLE OF DISTINGUISHING NORMAL CELLS FROM MALIGNANT CELLS, Hillary G. Caruso
CD56-SPECIFIC T CELLS: USING GENETICALLY ENGINEERED T CELLS TO REDIRECT SPECIFICITY TO A T CELL EXPRESSED ANTIGEN, Denise L. Crossland
Change Detection in Rhesus Monkeys and Humans, Deepna T. Devkar and Deepna T. Devkar
CHARACTERIZATION OF FTSA-FTSN INTERACTION DURING ESCHERICHIA COLI CELL DIVISION, kimberly.busiek@gmail.com K. Busiek
Characterization of the New Xoft Axxent Electronic Brachytherapy Source Using PRESAGE(TM), Jennifer Sierra Irwin
CHARACTERIZATION OF THE VASCULAR PATHOLOGY IN THE ACTA2 R258C MOUSE MODEL AND CEREBROVASCULAR CHARACTERIZATION OF THE ACTA2 NULL MOUSE, Carlos A. Villamizar
COMBINATION THERAPY WITH AEROSOL IL-2 AND NK CELLS FOR THE TREATMENT OF OSTEOSARCOMA LUNG METASTASIS, Sergei R. Guma
CONTRIBUTION OF INTERLEUKIN 6 TRANS SIGNALING IN PULMONARY FIBROSIS, Thuy T. Le
DEVELOPMENT OF A MOLECULAR GRAM-STAIN ASSAY FOR THE DIAGNOSIS OF BLOOD STREAM INFECTIONS ASSOCIATED WITH SEPSIS, Douglas Bryan Litwin
DEVELOPMENT OF A MULTI-PURPOSE AUTOMATED SYNTHESIS MODULE FOR PRODUCTION OF NOVEL PET RADIOPHARMACEUTICALS, I Hong Shih
Development of a New Independent Monte Carlo Dose Calculation Quality Assurance Audit Tool for Clinical Trials, Austin M. Faught
DEVELOPMENT OF CHIMERIC TYPE IV SECRETION SYSTEMS FOR TRANSFER OF HETEROLOGOUS SUBSTRATES ACROSS THE GRAM-NEGATIVE CELL ENVELOPE, Trista M. Berry
DIABETES AND OBESITY INDUCE TRANSCRIPTOMIC AND METABOLOMIC CHANGES ENHANCING PANCREATIC CANCER AGGRESSIVENESS, Guermarie Velázquez Torres
Differential regulation of IRESs in the Aurora A mRNA by bFGF through the mTOR complex TORC2 modulates Aurora A kinase expression, Roy L. Voice III