Baylor College of Medicine is a health sciences university that creates knowledge and applies science and discoveries to further education, healthcare and community service locally and globally. Learn more about our mission, vision and values.

Manuscripts submitted for publication (preprints), peer-reviewed pre-publication articles (postprints), and published articles from the faculty of Baylor College of Medicine are posted here with additional links to supplemental data.

Ranked 20th in the nation, and first in Texas since 2006 for obtaining National Institutes of Health (NIH) funding, Baylor College of Medicine received $687 million in total funding from 2,792 sponsored project awards in fiscal year 2023. Baylor operates more than 90 research and patient-care centers and units. BCM also operates more than 27 Advanced Technology Core Laboratories that provide services for studies in areas like metabolomics, proteomics, pathology, and genomics.

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Submissions from 2022

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Association of PD-L1 Expression and Other Variables With Benefit From Immune Checkpoint Inhibition in Advanced Gastroesophageal Cancer: Systematic Review and Meta-analysis of 17 Phase 3 Randomized Clinical Trials, Harry H Yoon, Zhaohui Jin, Oudom Kour, et al.

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Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer, Adelaide Young, Wen Bu, Weiyu Jiang, et al.

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RSPO2 and RANKL Signal Through LGR4 To Regulate Osteoclastic Premetastatic Niche Formation and Bone Metastasis, Zhiying Yue, Xin Niu, Zengjin Yuan, et al.

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Retinoic Acid Receptor Activation Reduces Metastatic Prostate Cancer Bone Lesions by Blocking the Endothelial-to-Osteoblast Transition, Guoyu Yu, Paul G Corn, Pengfei Shen, et al.

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Skp2 Stabilizes Mcl-1 and Confers Radioresistance in Colorectal Cancer, Xinfang Yu, Li Zhou, Wenbin Liu, et al.

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Spatial Definition of the Human Progesterone Receptor-B Transcriptional Complex, Xinzhe Yu, Ping Yi, Anil K Panigrahi, et al.

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ERK Inhibitor Ulixertinib Inhibits High-Risk Neuroblastoma Growth In Vitro and In Vivo, Yang Yu, Yanling Zhao, Jongmin Choi, et al.

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New, Potent, Small Molecule Agonists of Tyrosine Kinase Receptors Attenuate Dry Eye Disease, Zhiyuan Yu, Shaon Joy, Tianxiong Mi, et al.

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Cathepsin S Is a Novel Target for Age-Related Dry Eye, Zhiyuan Yu, Jinmiao Li, Gowthaman Govindarajan, et al.

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Assessment for Deeper Understanding using Concept Maps: Lessons Learned from Flipped Teaching of Pharmacology, Munder Zagaar and Weichao Chen

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cGAS-Sting Activation Contributes to Podocyte Injury in Diabetic Kidney Disease, Nan Zang, Chen Cui, Xinghong Guo, et al.

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Parental Mosaicism for Apparent De Novo Genetic Variants: Scope, Detection, and Counseling Challenges, Roni Zemet, Ignatia B Van den Veyver, and Paweł Stankiewicz

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PPM1D in Solid and Hematologic Malignancies: Friend and Foe?, Linda Zhang, Joanne I Hsu, and Margaret A Goodell

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PPM1D in Solid and Hematologic Malignancies: Friend and Foe?, Linda Zhang, Joanne I Hsu, and Margaret A Goodell

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A Large-Scale Genome-Wide Gene-Gene Interaction Study of Lung Cancer Susceptibility in Europeans With a Trans-Ethnic Validation in Asians, Ruyang Zhang, Sipeng Shen, Yongyue Wei, et al.

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Spectral Clustering of Single-Cell Multi-Omics Data on Multilayer Graphs, Shuyi Zhang, Jacob R Leistico, Raymond J Cho, et al.

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Gene Therapy Knockdown of Hippo Signaling Resolves Arrhythmic Events in Pigs After Myocardial Infarction, Sui Zhang, Shijie Liu, John P Leach, et al.

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Imbalanced IL-37/TNF-α/CTSS Signaling Disrupts Corneal Epithelial Barrier in a Dry Eye Model In Vitro, Yun Zhang, Jin-Miao Li, Rong Lu, et al.

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In Silico Analysis of DND1 and Its Co-Expressed Genes in Human Cancers, Yun Zhang, Yafang Li, Dhruv Chachad, et al.

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Combination of AIBP, apoA-I, and Aflibercept Overcomes Anti-VEGF Resistance in Neovascular AMD by Inhibiting Arteriolar Choroidal Neovascularization, Zhao Zhang, Megan M Shen, and Yingbin Fu

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Activity Disruption Causes Degeneration of Entorhinal Neurons in a Mouse Model of Alzheimer’s Circuit Dysfunction, Rong Zhao, Stacy D Grunke, Caleb A Wood, et al.

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Yap and Taz Promote Osteogenesis and Prevent Chondrogenesis In Neural Crest Cells In Vitro and In Vivo, Xiaolei Zhao, Li Tang, Tram P Le, et al.

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Elevated NRAS Expression During DCIS Is a Potential Driver for Progression to Basal-Like Properties and Local Invasiveness, Ze-Yi Zheng, Hanan Elsarraj, Jonathan T Lei, et al.

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Lipid-Lowering Therapy Use and Intensification Among United States Veterans Following Myocardial Infarction or Coronary Revascularization Between 2015 and 2019, Alexander R Zheutlin, Catherine G Derington, Jennifer S Herrick, et al.

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Disruption of MeCP2-TCF20 Complex Underlies Distinct Neurodevelopmental Disorders, Jian Zhou, Hamdan Hamdan, Hari Krishna Yalamanchili, et al.