The ​Children’s Nutrition Research Center (CNRC) is a unique cooperative venture between Baylor College of Medicine, Texas Children's Hospital and the U.S. Department of Agriculture/Agricultural Research Service (USDA/ARS). The center has 50 faculty members conducting nutrition-related research and a total staff of more than 200.

Texas Children's is creating a healthier future for children and women across our global community through our leadership in patient care, education and research. We’re proud of the daily efforts that build into cumulative medical results and discoveries accomplished by each of our institutions.

The Children’s Nutrition Research Center is the first federal nutrition research center to investigate the nutritional needs of children from conception through adolescence, and that of pregnant women and nursing mothers. It is 1 of 6 U.S. Department of Agriculture human nutrition research centers conducting scientific investigations designed to provide Americans with a clear understanding of the role of nutrition in maintaining a healthy, active life.

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Submissions from 2025

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A Brief Guide to Statistical Analysis of Grouped Data in Preclinical Research, Colby J Vorland, Lilian Golzarri-Arroyo, and David B Allison

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Distinct Adipose Progenitor Cells Emerging With Age Drive Active Adipogenesis, Guan Wang, Gaoyan Li, Anying Song, et al.

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Genetic Architecture and Analysis Practices of Circulating Metabolites in the Nhlbi Trans-Omics for Precision Medicine Program, Nannan Wang, Franklin P Ockerman, Laura Y Zhou, et al.

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Dual Inhibitor of MDM2 and NFAT1 for Experimental Therapy of Breast Cancer: In Vitro and In Vivo Anticancer Activities and Newly Discovered Effects on Cancer Metabolic Pathways, Wei Wang, Marlene Aguilar, Sayantap Datta, et al.

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Whole-Genome Sequencing Reveals Individual and Cohort Level Insights Into Chromosome 9p Syndromes, Yingxi Wang, Eleanor I Sams, Rachel Slaugh, et al.

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Inhibition of Srebp-1c Rescues Hepatic CYP7B1 Expression and Bile Acid Synthesis in Malnourished Mice, Xiaoyang Wan, Krishnakant G Soni, Jong Min Choi, et al.

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Refinement of a Published Gene-Physical Activity Interaction Impacting HDL-Cholesterol: Role of Sex and Lipoprotein Subfractions, Kenneth E Westerman, Tuomas O Kilpeläinen, Magdalena Sevilla-Gonzalez, et al.

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Changes in the Fxr-Cistrome and Alterations in Bile Acid Physiology in Wilson Disease, Clavia Ruth Wooton-Kee, Hari K Yalamanchili, Islam Mohamed, et al.

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A Reflection-Spectroscopy Measured Skin Carotenoid Score Strongly Correlates With Plasma Concentrations of All Major Dietary Carotenoid Species Except for Lycopene, Qiang Wu, Cheryl Webb Cherry, Stephanie Jilcott Pitts, et al.

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Risk Score Roulette: A Cautionary Tale of Polygenic Risk Score Reliability, Diane Xue, Elizabeth E Blue, Alexis C Wood, et al.

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A Novel Self-Inhaled Nicotine Exposure System in Murine Models Reveals Age-Dependent Metabolic Effects of Nicotine, Xu Xu, Hailan Liu, Meng Yu, et al.

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Co-Targeting Bcl-xL with Mcl-1 Induces Lethal Mitochondrial Dysfunction in Diffuse Mesothelioma, Yuan Xu, Cristian G Medina, Deborah R Surman, et al.

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Bypassing Cisplatin Resistance in Nrf2 Hyperactivated Head and Neck Cancer Through Effective PI3Kinase Targeting, Pedram Yadollahi, Kelli A McCord, Yang Li, et al.

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Predicting Five-Year Comorbid Bipolar Disorder After Attention-Deficit/Hyperactivity Disorder Diagnosis: A Population-Based Machine Learning Approach, Yen-Shan Yang, Chih-Wei Hsu, Liang-Jen Wang, et al.

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Author Correction: Orthogonal and Multiplexable Genetic Perturbations With an Engineered Prime Editor and a Diverse RNA Array, Qichen Yuan, Hongzhi Zeng, Tyler C Daniel, et al.

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Mapping Epidermal and Dermal Cellular Senescence in Human Skin Aging, Grace T Yu, Clarisse Ganier, David B Allison, et al.

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Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress, Jianpeng Yu, Chen Jin, Cheng Su, et al.

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Suppression of Hypothalamic Oestrogenic Signal Sustains Hyperprolactinemia and Metabolic Adaptation in Lactating Mice, Meng Yu, Bing Feng, Jonathan C Bean, et al.

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Altered Thermal Preference by Preoptic Estrogen Receptor Alpha Neurons in Postpartum Females, Nan Zhang, Meng Yu, Qianru Zhao, et al.

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The Adiponectin-PPARγ Axis in Hepatic Stellate Cells Regulates Liver Fibrosis, Shangang Zhao, Qingzhang Zhu, Wang-Hsin Lee, et al.

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Genetics-Nutrition Interactions Control Diurnal Enhancer-Promoter Dynamics and Liver Lipid Metabolism, Dishu Zhou, Ying Chen, Panpan Liu, et al.

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Adipose Progenitor Cell-Derived Extracellular Vesicles Suppress Macrophage M1 Program To Alleviate Midlife Obesity, Qing Zhou, Jia Gao, Guorao Wu, et al.

Submissions from 2024

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Alzheimer's Disease Risk Gene CD2AP Is a Dose-Sensitive Determinant of Synaptic Structure and Plasticity, Taeyong Ahn, Gabrielle E Largoza, Julia Younis, et al.

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CPSF3 Inhibition Blocks Pancreatic Cancer Cell Proliferation Through Disruption of Core Histone mRNA Processing, Abdulrahman A Alahmari, Aditi H Chaubey, Venkata S Jonnakuti, et al.

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Relationship Between Food Security, Nutrition Security, and Diabetes: the Role of Supplemental Nutrition assistance Program Participation, Maha Almohamad, Jayna M Dave, Eric E Calloway, et al.