Open-access, full-text copies of The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.
Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.
Older GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.
Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.
Theses/Dissertations from 2018
A Compressed Sensing Approach to Detect Immobilized Nanoparticles Using Superparamagnetic Relaxometry, Sara Thrower
ADENYLYL CYCLASE TYPE 9: REGULATION AND CARDIAC FUNCTION, Tanya A. Baldwin and Tanya A. Baldwin
Aging Exacerbates Neutrophil Pathogenicity in Ischemic Stroke, Meaghan Roy-O'Reilly
A ROLE FOR EPAC1 AND EPAC2 IN NOCICEPTOR HYPEREXCITABILITY AND CHRONIC PAIN AFTER SPINAL CORD INJURY, Samantha Berkey
ASSEMBLY AND DISPLAY OF SURFACE PROTEINS IN ACTINOMYCES ORIS, Sara Siegel
Attitudes Toward Updated Genetic Testing Among Patients with Unexplained Mismatch Repair Deficiency, Jessica Omark
AUTO-DELINEATION OF OROPHARYNGEAL CLINICAL TARGET VOLUMES USING DEEP LEARNING TECHNIQUES, Carlos Eduardo Cardenas
Bayesian Designs for Early Phase Clinical Trials with Novel Target Agents, Heng Zhou
BAYESIAN INTEGRATIVE ANALYSIS OF OMICS DATA, Youyi Zhang
BIOLOGICAL CLOCKS, INFLAMMATION, AND MULTIORGAN DAMAGE IN SICKLE CELL DISEASE, Morayo Adebiyi
CHANGES IN THE TESTES FOLLOWING SPINAL CORD INJURY AND THE ATTENUATING EFFECTS OF LICOFELONE, Ryan Fortune
CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS, Sarah Azam
CHARACTERIZATION OF METRONIDAZOLE- AND VANCOMYCIN-RESISTANT CLINICAL ISOLATES OF CLOSTRIDIUM DIFFICILE, Chioma Odo
Characterizing the recognition motif and novel substrates of CARM1, Sitaram gayatri
Cholinergic Control of Cortical Circuit Activity, Rajan Dasgupta
Computational insights into the generation of chromosomal copy number changes, Yihua Liu
CURRENT GENETIC COUNSELING PRACTICE FOLLOWING POSITIVE NON-INVASIVE PRENATAL TESTING FOR SEX CHROMOSOME ABNORMALITIES, Lauren Fleddermann
Design, Fabrication, and Validation of 3D Printed, Patient-Specific Compensators for Postmastectomy Radiation Therapy, Daniel Craft
Development and Characterization of a Bi-specific Antibody Targeting HLA-A2/PR1, Amanda Herrmann
Development and Commissioning of an Independent Peer Review System for a Small Animal Irradiator, Mary Peters
DEVELOPMENT OF 3D-PRINTED PATIENT SPECIFIC BOLUS FOR CLINICAL USE IN TOTAL SCALP IRRADIATION, Garrett Baltz
Discovery and effects of pharmacological inhibition of the E3 ligase Skp2 by small molecule protein-protein interaction disruptors, John K. Morrow
DISSECTING THE MOLECULAR MECHANISM OF EARLY TUMOR DISSEMINATION IN NON-SMALL CELL LUNG CANCER, Xingtong Liu
ENHANCING RADIATION SENSITIVITY IN NON-SMALL CELL LUNG CANCER, Yifan Wang
EPITHELIAL TO MESENCHYMAL TRANSITION AS A PREDICTOR OF RESPONSE TO POLO-LIKE KINASE 1 INHIBITION-INDUCED APOPTOSIS IN NON-SMALL CELL LUNG CARCINOMA, Pavitra Viswanath
EQUIPMENT TO ADDRESS INFRASTRUCTURE AND HUMAN RESOURCE CHALLENGES FOR RADIOTHERAPY IN LOW-RESOURCE SETTINGS, Rachel McCarroll
EVALUATION OF PRESAGE® AS A 3D DOSE VERIFICATION TOOL IN PROTON BEAMS, Mitchell Carroll
EVOLUTION VIA GENE DUPLICATION AND ALTERNATIVE SPLICING IN THE EUKARYOTIC SKI7 AND HBS1 GENES, Alexandra Marshall
EXAMINING THE RELATIONSHIP BETWEEN GENETIC COUNSELORS’ IMPLICIT ATTITUDES TOWARD DISABILITY AND THEIR PRACTICE METHODS, Helen W. Gould
FUNCTIONAL HETEROGENEITY OF FIBROBLASTS IN DERMAL WOUND HEALING, Ehsan Ehsanipour
Functional Similarity of PRD-Containing Virulence Regulators in Bacillus anthracis, Malik Raynor
GENETIC EVOLUTION AND PROGNOSTIC DETERMINANTS OF PANCREATIC CANCER ON LONGITUDINAL LIQUID BIOPSIES, Vincent Bernard
GENOMIC AND TRANSCRIPTOMIC LANDSCAPE OF COLORECTAL PREMALIGNANCY, Kyle Chang
Genomic Evolution of Chemoresistance in Triple-Negative Breast Cancer Delineated by Single Cell Sequencing, Charissa Kim
HEME PEROXIDASE HPX-2 PROTECTS CAENORHABDITIS ELEGANS FROM PATHOGENS, Yi Liu
HYPOTHALAMIC CIRCUITS IN THE CONTROL OF FEEDING AND EMOTIONAL BEHAVIORS, Leandra Mangieri
IDENTIFICATION AND UTILITY OF DNA IN EXOSOMES, Paul Kurywchak
Identification of Intracranial Lesions with Dual-Energy Computed Tomography and Magnetic Resonance Phase Imaging, Megan C. Jacobsen
IDENTIFICATION OF TISSUE AND CIRCULATING BIOMARKERS FOR PREMALIGNANT AND MALIGNANT LESIONS, SHU-HONG LIN
IDENTIFYING MOLECULAR TARGETS AND VALIDATING NOVEL THERAPIES FOR OVARIAN CANCER, Alejandro Villar-Prados
Identifying Subunit Organization and Function of the Nuclear RNA Exosome Machinery, Jillian Losh
IL-1α BLOCKADE REDUCES IMMUNE SUPPRESSION IN THE EARLY TUMOR MICRO-ENVIRONMENT, Brenda Melendez
Improved Target Coverage of Spinal Metastases Through the Use of Flattening Filter Free Beams, Laura Bennett
Improving dbNSFP, Mingyao Lu
INSIGHTS INTO THE REACTIVATION, REGULATION AND ESSENTIALITY OF OXIDATIVE PROTEIN FOLDING PATHWAYS IN ACTINOBACTERIA, Belkys Sanchez
INTEGRATIVE BIOINFORMATICS APPROACHES TO ELUCIDATING PROSTATE CANCER CELL HETEROGENEITY, PLASTICITY, AND TREATMENT RESPONSE, Hsueh-Ping Chao
Intratumoral STING Activation Sensitizes Poorly Immunogenic Cancers to Checkpoint Blockade Immunotherapy, Casey Ager
INVESTIGATING INVASION IN DUCTAL CARCINOMA IN SITU WITH TOPOGRAPHICAL SINGLE CELL GENOME SEQUENCING, Anna Casasent and Anna Casasent
INVESTIGATING THE IMPACT OF INTRAGENIC DNA METHYLATION ON GENE EXPRESSION, AND THE CLINICAL IMPLICATIONS ON TUMOR CELLS AND ASSOCIATED STROMA, Michael McGuire
INVESTIGATING THE ROLES OF TAP63 AND TAP73 IN CUTANEOUS SQUAMOUS CELL CARCINOMA AND LUNG ADENOCARCINOMA, Andrew J. Davis
INVESTIGATING THE SINGLE CELL HETEROGENEITY AND PHYSIOLOGICAL IMPACT OF MISTRANSLATION, Christopher Evans
Investigation of Novel Virulence Mechanisms in Candida albicans, Elisa Marie Tafoya Vesely
INVOLVEMENT OF GDAP1 IN THE REGULATION OF MTORC1 ACTIVITY IN A DROSOPHILA MLIV MODEL, Kristen Clemons
ISCHEMIC STROKE DAMAGE IS REDUCED BY INHIBITION OF IL-6 SIGNALING WITH TOCILIZUMAB, Jacob Hudobenko
Mechanism of Incorporation and Repair of Uracil at Highly Transcribed Genes In Saccharomyces Cerevisiae, Norah Auma Owiti
MECHANISMS AND TARGETING OF NEURODEVELOPMENTAL REGULATOR REST IN MEDULLOBLASTOMA DISSEMINATION, Keri Callegari
MICRORNA FUNCTIONS IN UV-INDUCED CUTANEOUS SQUAMOUS CELL CARCINOMA, Tran Nguyen
miR-484 Functions as an Onco-miR in Triple Negative Breast Cancer, Nashwa Kabil
Nanoscale Organization of the Small GTPase Rac1, Kelsey Maxwell
Omics Approaches to Uncover Germline and Somatic Variation Underlying Inherited Sarcomagenesis, Justin Wong
Outcomes of Genetic Testing in a Genitourinary Genetics Clinic, Annelise Pace
Patient Attitudes Toward Genetic Testing for Inherited Predispositions to Hematologic Malignancies, Taylor Beecroft
PHOSPHORYLATION IMPAIRS DICER1 FUNCTION TO ACCELERATE AGING AND TUMORIGENESIS IN VIVO, Neeraj Aryal
POPULATION CODES AND THEIR CORRELATES IN DECISION MAKING, Neda Shahidi
Psychiatric Impact of Tuberous Sclerosis Complex and Utilization of Mental Health Treatment, Kate Mowrey
ROLE OF P300 ZZ DOMAIN IN CHROMATIN ASSOCIATION AND HISTONE ACETYLATION, Yongming Xue
SIMVASTATIN DOES NOT SENSITIZE IBC3 HER2+ INFLAMMATORY BREAST CANCER BRAIN METASTASES TO WHOLE BRAIN IRRADIATION IN AN IMMUNOCOMPROMISED MOUSE MODEL, Swaminathan Kumar
Somatostatin Receptor 2 Regulation by C-terminal Motifs and PDZ Domain Proteins, Courtney Olsen
SPHINGOSINE KINASE 1 REGULATES FASCIN EXPRESSION TO PROMOTE METASTASIS IN TRIPLE NEGATIVE BREAST CANCER, Sunil Acharya
STRUCTURE BASED DRUG DESIGN OF HIGH AFFINITY KRAS INHIBITORS, Michael McCarthy
Targeting PH domain proteins for cancer therapy, Zhi Tan
The Cross-Talk Between Neurons and Microglia Through Interleukin-4 After Ischemic Injury, Shun-Ming Ting
The Epithelial To Mesenchymal Transition In Breast Cancer Induces Alterations In Metabolism, Esmeralda Ramirez-Peña
THE PROTECTIVE EFFECTS OF MEMANTINE ON THE MORPHOLOGY AND ACTIVITY OF IRRADIATED DENDRITIC SPINES, Thanh Lam
The Regulation of DNA Methylation in Mammalian Development and Cancer, Nicolas Veland
The Role of Merlin and Apicobasal Polarity in Endometrial Development and Homeostasis, Erin Lopez
The Role of Perivascular FIbrosis in Post-Stroke Glymphatic Impairment and Cerebral Amyloid Angiopathy, Matthew D. Howe
The Role of Tumor Suppressor DEAR1 in the Acquisition of Mammary Stem/Progenitor Cell Properties, Uyen Le
TRICHURIS MURIS WHEY ACIDIC PROTEIN INDUCES TYPE 2 PROTECTIVE IMMUNITY AGAINST WHIPWORM, Neima Briggs
TRIM24 as an Oncogene in the Mammary Gland, Aundrietta Duncan
Trim24 in Normal & Malignant Hematopoiesis, Justin Shaw
TUMOR IMMUNOTHERAPY: MECHANISMS OF ACQUIRED RESISTANCE AND CHARACTERIZATION OF IMMUNE RELATED TOXICITIES, Ashvin Jaiswal
UBE4B LEVELS DETERMINE THE EFFICACY OF EGFR AND STAT5 INHIBITORS IN TREATMENT RESISTANT NEUROBLASTOMA, David James Savage
VASCULAR INJURY IN Col3a1+/- MICE MODEL OF VASCULAR EHLER-DANLOS SYNDROME, Ping ZHOU MS
Theses/Dissertations from 2017
A LICENSE TO KILL: UNDERSTANDING NATURAL KILLER CELL LICENSING TO FIGHT CANCER, Jolie Schafer
ANALYSIS OF THE BIOCHEMICAL AND CELLULAR ACTIVITIES OF SUBSTRATE BINDING BY THE MOLECULAR CHAPERONE HSP110/SSE1, Veronica M. Garcia
ANDROGEN RECEPTOR AND PROSTATE CANCER CELL HETEROGENEITY, Qu Deng
A PRECLINICAL STUDY OF RADIATION-INDUCED LUNG TOXICITY WHEN IRRADIATING IN A STRONG MAGNETIC FIELD, Ashley E. Rubinstein
A tail-based test for differential expression analysis and pathway analysis in RNA-sequencing data, Jiong Chen
Attitudes of Clinicians Towards Cardiac Surgery and Trisomy 18, Meagan Kaulfus
Attitudes Toward and Uptake of Prenatal Genetic Screening and Testing in Twin Pregnancies, Kathryn M. Reese
Barriers to Expansion of Supervision Networks at Genetic Counseling Training Programs, Jordan E. Berg
CD47+ Exosomes Facilitate Effective Targeting of Oncogenic Kras in Pancreatic Cancer, Sushrut Kamerkar
CHARACTERIZATION AND REVERSAL OF DOXORUBICIN-MEDIATED CHANGES IN SENSORY NEURONS, Brittany L. Coughlin
CHARACTERIZATION OF NOTCH1 AND PI3K-PTEN-AKT/mTOR PATHWAY INTERACTION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA, Kyriante' Henry