Open Access full-text copies of the UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Older UT GSBS dissertations (from approximately 1979-1999) are available in print format only, inThe TMC Library. They're listed in the Library Catalog under the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

Some older full-text dissertations are also available via ProQuest, but full-text access to these dissertations is restricted to The TMC Library's academic user group.

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Theses/Dissertations from 2015

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Induction of caspase-dependent death by proteasome targeted therapy in glioblastoma, Christa A. Manton

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INFLUX AND EFFLUX OF ADENINE NUCLEOTIDES FROM ERYTHROCYTES REGULATE OXYGEN TRANSPORT AND SYSTEMIC METABOLISM, William G. O'Brien III

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Investigating the Interaction of AURKA and UBE2C in Colorectal Cancer Cells, Apurva M. Hegde

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INVESTIGATING THE ROLE OF CHOLESTEROL METABOLISM AND SYNTHESIS IN METASTASIS AND RADIATION RESPONSE IN AGGRESSIVE SUBTYPES OF BREAST CANCER, Adam Wolfe

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Investigating the roles of p63 and p73 isoforms to therapeutically treat p53-altered cancers, Avinashnarayan Venkatanarayan

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INVESTIGATION OF GENETIC ALTERATIONS IN EMT SUPPRESSOR, DEAR1, THROUGH PAN-CANCER ANALYSIS AND ULTRA-DEEP TARGETED SEQUENCING IN DUCTAL CARCINOMA IN SITU, Jacquelyn Reuther

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INVESTIGATION OF QUATITATIVE IMAGE FEATURES FROM PRETREATMENT CT AND FDG-PET SCANS IN STAGE III NSCLC PATIENTS UNDERGOING DEFINTIVE RADIATION THERAPY, David Fried

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INVESTIGATION OF THE ROLE OF THE SCAFFOLD PROTEIN SHC IN ERK SIGNALING, kin man suen

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IN VIVO FUNCTIONAL SIGNIFICANCE OF CCAT2 LONG NON-CODING RNA IN MYELODYSPLASTIC SYNDROME, MAITRI Y. SHAH

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IN VIVO SIGNIFICANCE OF THE MDM4 AND P73 INTERACTION DURING DEVELOPMENT AND TUMORIGENESIS, Mehrnoosh Tashakori

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Isoform Selective Regulation of Adenylyl Cyclase by Small Molecule Inhibitors and Gbetagamma Protein, Cameron S. Brand

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KNOWLEDGE AND SELF-ESTEEM IN INDIVIDUALS WITH NEUROFIBROMATOSIS TYPE 1 (NF1), Kayla Vaughn

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MEASURING SINGLE CELL RESPONSES TO LAPATINIB IN A HETEROGENEOUS POPULATION, Preety Priya

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MERLIN MEDIATED REGULATION OF HAIR FOLLICLE MORPHOGENESIS, Megan K. Fentress

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Metabolic profiling of prions in the gastro-intestinal tract, Uffaf Khan

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Methylation of EGFR by Arginine Methyltransferase PRMT1 Enhances EGFR Signaling and Cetuximab resistance, Hsin-Wei Liao

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MICRORNA-200 REGULATES ECM-DEPENDENT β1-INTEGRIN/FAK SIGNALING AND CANCER CELL INVASION, Christin Ungewiss

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Mobilization of Adipose Stromal Cells in Obesity and Cancer by SPARC and its Proteolytic Isoforms, Chieh Tseng

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MOLECULAR REGULATION OF VASCULAR CALCIFICATION IN MURINE MODELS OF ATHEROSCLEROSIS, Shanshan Gao

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MULTILEVEL DEREGULATION OF SURVIVAL MECHANISMS IN NPM-ALK+ T-CELL LYMPHOMA, Deeksha Vishwamitra

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NEW INSIGHTS ON THE ROLE OF JMJD2A IN CANCER PROGRESSION, Yuan Gao

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NFAT1 CONTRIBUTES TO MELANOMA TUMOR GROWTH AND METASTASIS BY REGULATING IL-8 AND MMP-3, Einav Shoshan

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Normal Glycolytic Enzyme Activity is Critical for Hypoxia Inducible Factor-1a Activity and Provides Novel Targets for Inhibiting Tumor Growth, Geoffrey Grandjean PhD

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Obstetrician and Gynecologist Utilization of the NIPT Expanded Testing Option, Sarah Mayes BA

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Oxidative protein folding pathways in Gram-positive Actinobacteria, Melissa E. Robinson

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PLASMACYTOID DENDRITIC CELL-MEDIATED HUMORAL AUTOIMMUNITY, Stephanie M. Dorta-Estremera Ph.D.

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POST-TRANSLATIONAL REGULATION OF ZEB1 CONTRIBUTES TO TGFβ-MEDIATED EMT, Roxsan Manshouri

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Prediction of Laser Ablation in Brain: Sensitivity, Calibration, and Validation, Samuel J. Fahrenholtz

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PREVENTING THYMUS INVOLUTION IN K5.CYCLIN D1 TRANSGENIC MICE SUSTAINS THE NAÏVE T CELL COMPARTMENT WITH AGE, Michelle L. Bolner

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Prophylactic Cranial Irradiation Reduces the Incidence of Brain Metastasis in a Mouse Model of Metastatic Breast Cancer, Daniel L. Smith

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QUALITY ASSURANCE OF ADVANCED TREATMENT MODALITIES USING PRESAGE® DOSIMETERS, Ryan G. Lafratta

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Quantification of IMRT severity scores for improvement of FMEA results, Jacqueline T. Faught

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REDIRECTING T CELLS WITH CHIMERIC ANTIGEN RECEPTORS TO TARGET CD123+ LEUKEMIA, Radhika Thokala

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REDUCTION OF DOSE CALCULATION ERRORS FOR PATIENTS WITH METAL IMPLANTS RECEIVING PHOTON RADIATION THERAPY, Jessie Huang-Vredevoogd

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Regulation of Autoimmune Germinal Center Reaction by Tfh Cells and Application of Tfr-like Cells for the Treatment of Autoimmune B Cell Responses, Young Uk Kim

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Regulation of Cell Adhesion by the FERM Proteins, PTPN14 and Merlin, Patty Dimarco Hewitt

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REGULATION OF THE OXIDATIVE STRESS RESPONSE BY ARID1A, Suet Yan Kwan

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REST REGULATORY CIRCUIT CONTROLS DISTINCT ONCOGENIC PROPERTIES OF GLIOBLASTOMA STEM CELLS THROUGH SPECIFIC MICRORNAs, Anantha L Marisetty

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ROLE OF STAT3 IN HUMAN NK CELL FUNCTIONS, Prasad V. Phatarpekar

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SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS: IN SUPPORT OF TRANSLATIONAL THERAPY, David Rushworth

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SERUM OMENTIN AS A POTENTIAL BIOMARKER FOR COMPLEX ATYPICAL HYPERPLASIA AND ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA, Laura L. Holman MD

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SOCIAL-DEMOGRAPHICS, HEALTH BEHAVIORS, TELOMERE LENGTH IN MEXICAN-AMERICAN COHORT AND CIRCULATING DNA METHYLATION IN BLADDER CANCER, Lixia Han

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Spiritual Exploration in the Prenatal Genetic Counseling Session, Katelynn G. Sagaser

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SRC HOMOLOGY 2 DOMAIN-CONTAINING 5’-INOSITOL PHOSPHATASE-2 (SHIP2) IS AN EFFECTOR OF LYMPHATIC DYSFUNCTION, Germaine D. Agollah

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Structure and Composition of Postsynaptic Densities, Madeline Farley

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SUNITINIB-INDUCED CARDIOTOXICITY EXPOSES MICROVASCULAR AND METABOLIC DERANGEMENTS IN THE FAILING HEART, Meredith R. Rodriguez

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SYNTHETIC LETHALITY OF CDK INHIBITION AND DOXORUBICIN IN TRIPLE-NEGATIVE BREAST CANCER REQUIRES P53 INACTIVATION, Natalie A. Jabbour-Leung

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TARGETED INHIBITION OF PI3K, MTOR, AND IGF1R FOR THE TREATMENT OF UNDIFFERENTIATED PLEOMORPHIC SARCOMA, Caitlin Denise May

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Targeting An Ancient Retrovirus During Melanoma Using Adoptive T Cells Therapy, janani Krishnamurthy

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Targeting oncogenic miRNAs with Small Molecules for Breast Cancer Therapy, Paloma del C. Monroig

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Texas Physicians' Awareness and Utilization of Genetic Services, Callie L. Jenevein

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THE EFFECT OF ACTIVATION INDUCED CYTIDINE DEAMINASE PHOSPHORYLATION AND HERPES VIRUS URACIL DNA GLYCOSYLASE ON ANTIBODY DIVERSIFICATION, Marc Macaluso

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THE EFFECT OF ROOM ENVIRONMENT ON PATIENT EXPERIENCE IN A PRENATAL GENETIC COUNSELING SESSION, Elizabeth C. Baack

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THERMAL ABLATION ALTERS THE TUMOR MICROENVIRONMENT ACTIVATING A ROBUST IMMUNE RESPONSE., Matthew T. Campbell M.D.

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THE ROLE OF AUTOPHAGY IN THE SENSITIVITY OF OSTEOSARCOMA CELLS TO GEMCITABINE TREATMENT, Janice M. Santiago-O'Farrill

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The role of DNA methylation and hydroxymethylation in smooth muscle cell phenotypic change during atherogenesis, jason Williams

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The Structural Mechanism of Allosteric Modulation of the NMDA Receptor: A Balance of Tensions, Rita E. Sirrieh

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THE TUMOR SUPPRESSOR NOTCH INHIBITS HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) TUMOR GROWTH AND PROGRESSION BY MODULATING PROTO-ONCOGENES AXL AND CTNNAL1 (α-CATULIN), Shhyam Moorthy and Shhyam Moorthy

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TRIM28 INTERACTS WITH EZH2 TO REGULATE ITS ACTIVITY, Jing Li and Jing Li

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TWO-COLOR FLUORESCENT ANALYSIS OF CONNEXIN 36 TURNOVER AND TRAFFICKING – RELATIONSHIP TO FUNCTIONAL PLASTICITY, Yanran Wang

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UNDERSTANDING THE ROLE OF SUMOYLATION IN REGULATING LKB1 FUNCTION, Joan W. Ritho

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VOXEL-LEVEL ABSORBED DOSE CALCULATIONS WITH A DETERMINISTIC GRID-BASED BOLTZMANN SOLVER FOR NUCLEAR MEDICINE AND THE CLINICAL VALUE OF VOXEL-LEVEL CALCULATIONS, Justin Mikell

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YAP1 expression predicts sensitivity to dual AKT/P70S6K inhibition in ovarian and uterine malignancies, Rebecca A. Previs

Theses/Dissertations from 2014

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ACTIVATING THE 4-1BB PATHWAY FOR THE EXPANSION OF TUMOR-INFILTRATING LYMPHOCYTES FOR ADOPTIVE T-CELL THERAPY FOR METASTATIC MELANOMA PATIENTS, Jessica Ann Chacon

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ACTIVATING THE 4-1BB PATHWAY FOR THE EXPANSION OF TUMOR-INFILTRATING LYMPHOCYTES FOR ADOPTIVE T-CELL THERAPY FOR METASTATIC MELANOMA PATIENTS, Jessica Ann Chacon

Anchoring and Uptake of Non-Invasive Prenatal Testing in the First and Second Trimester, Amanda S. Hanson

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ANGIOMOTIN IS A NOVEL CADHERIN-11 INTERACTING PROTEIN THAT MEDIATES MIGRATION IN PROSTATE CANCER CELLS, Angelica Ortiz

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A NOVEL TABLET BASED SYSTEM TO MEASURE THE EFFECT OF SUBCONCUSSIVE BLOWS ON SENSORIMOTOR AND COGNITIVE FUNCTIONING, Stuart D. Red

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Anti-GD2 Etoposide-Loaded Immunoliposomes for the Treatment of GD2 Positive Tumors, Brandon S. Brown

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ANTI-INSULIN RESISTANCE TREATMENTS SUPPRESS HER2+ BREAST CANCER GROWTH VIA ALTERING METABOLISM, PING-CHIEH CHOU

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Availability Of Dental Anomaly Phenotype In Individuals With Familial Adenomatous Polyposis, Andrea M. Lewis

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Bioactivity and Cell-Mediated Targeting of Multistage Nanoporous Silicon Particles, Jonathan O. Martinez

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BRIT1/MCPH1 MEDIATES THE DNA DAMAGE RESPONSE BY INDUCING P53 STABILITY AND PROMOTING ATR SIGNALING, Edward Wang

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Cancer Diagnosis During Pregnancy: Evaluating the Challenges Faced by Oncologists, Shannon Kaye Mulligan

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Cancers Associated with BRCA1 and BRCA2 Mutations Other Than Breast and Ovarian, Jacqueline Mersch

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CAR-MODIFIED T CELLS CAPABLE OF DISTINGUISHING NORMAL CELLS FROM MALIGNANT CELLS, Hillary G. Caruso

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CD56-SPECIFIC T CELLS: USING GENETICALLY ENGINEERED T CELLS TO REDIRECT SPECIFICITY TO A T CELL EXPRESSED ANTIGEN, Denise L. Crossland

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Change Detection in Rhesus Monkeys and Humans, Deepna T. Devkar and Deepna T. Devkar

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CHARACTERIZATION OF FTSA-FTSN INTERACTION DURING ESCHERICHIA COLI CELL DIVISION, kimberly.busiek@gmail.com K. Busiek

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Characterization of the New Xoft Axxent Electronic Brachytherapy Source Using PRESAGE(TM), Jennifer Sierra Irwin

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CHARACTERIZATION OF THE VASCULAR PATHOLOGY IN THE ACTA2 R258C MOUSE MODEL AND CEREBROVASCULAR CHARACTERIZATION OF THE ACTA2 NULL MOUSE, Carlos A. Villamizar

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COMBINATION THERAPY WITH AEROSOL IL-2 AND NK CELLS FOR THE TREATMENT OF OSTEOSARCOMA LUNG METASTASIS, Sergei R. Guma

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COMPETITION BETWEEN GRB2 AND PLCγ1 FOR BINDING TO FGFR2 REGULATES PHOSPHOLIPASE AND PTEN ACTIVITY, LEADING TO CELL INVASION AND PROLIFERATION, zahra timsah

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CONTRIBUTION OF INTERLEUKIN 6 TRANS SIGNALING IN PULMONARY FIBROSIS, Thuy T. Le

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Development and Implementation of an Anthropomorphic Pediatric Spine Phantom for the Assessment of Craniospinal Irradiation Procedures in Proton Therapy, Dana Lewis

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DEVELOPMENT OF A MOLECULAR GRAM-STAIN ASSAY FOR THE DIAGNOSIS OF BLOOD STREAM INFECTIONS ASSOCIATED WITH SEPSIS, Douglas Bryan Litwin

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DEVELOPMENT OF A MULTI-PURPOSE AUTOMATED SYNTHESIS MODULE FOR PRODUCTION OF NOVEL PET RADIOPHARMACEUTICALS, I Hong Shih

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Development of a New Independent Monte Carlo Dose Calculation Quality Assurance Audit Tool for Clinical Trials, Austin M. Faught

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DEVELOPMENT OF CHIMERIC TYPE IV SECRETION SYSTEMS FOR TRANSFER OF HETEROLOGOUS SUBSTRATES ACROSS THE GRAM-NEGATIVE CELL ENVELOPE, Trista M. Berry

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DIABETES AND OBESITY INDUCE TRANSCRIPTOMIC AND METABOLOMIC CHANGES ENHANCING PANCREATIC CANCER AGGRESSIVENESS, Guermarie Velázquez Torres

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DIFFERENTIAL PAX5 LEVELS PROMOTE MCL DISPERSAL AND PROGRESSION AND PREDICT A POOR PROGNOSIS IN ADVANCED MCL PATIENTS, Albert Teo

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Differential regulation of IRESs in the Aurora A mRNA by bFGF through the mTOR complex TORC2 modulates Aurora A kinase expression, Roy L. Voice III

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DISCOVERY AND ELUCIDATION OF THE FGFR3-TACC3 RECURRENT FUSION IN GLIOBLASTOMA, Brittany C. Parker Kerrigan

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DISSECTING THE ROLES OF TRIM24 IN REGULATION OF HEPATIC LIPID METABOLISM AND INFLAMMATION, Lindsey C. Minter

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DUAL ASSEMBLY NANOPARTICLES ACHIEVE SUSTAINED SILENCING OF ZNF304: A NOVEL TRANSCRIPTION FACTOR FOR Β1 INTEGRIN, Burcu Aslan

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Effects of oxytocin on human aggression, Joseph L. Alcorn III

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EFFECTS OF RESTING STATE ON PERCEPTUAL LEARNING, Sarah Eagleman Ph.D.

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EGFR Modulates MicroRNA Maturation In Response To Hypoxia Through Phosphorylation Of Argonaute2, Jia Shen

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ENERGY STRESS CAUSES CHAPERONES TO ASSEMBLE INTO CYTOPLASMIC COMPLEXES, Kimberly J. Cope

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EPIDERMAL GROWTH FACTOR RECEPTOR INDUCES FYN EXPRESSION VIA UP-REGULATION OF P47PHOX IN GLIOBLASTOMA MULTIFORME, Blake P. Johnson