Open-access, full-text copies of UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Older UT GSBS dissertations (from approximately 1979-1999) are available in print format only, in The TMC Library. They are listed in the Catalog. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list.

Some older GSBS dissertations are available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.

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Theses/Dissertations from 2016

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Utilizing Computed Tomography Image Features to Advance Prediction of Radiation Pneumonitis, Shane P. Krafft

Theses/Dissertations from 2015

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ACTIONS OF PI3K-DELTA INHIBITOR, IDELALISIB, AND ITS COMBINATION WITH BENDAMUSTINE IN CHRONIC LYMPHOCYTIC LEUKEMIA, Prexy Modi

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ANKYRIN-B AND mTOR COMPLEX 1 IN THE REGULATION OF ELECTRICAL ACTIVITIES IN THE HEART, Henry C. Wu and Henry C. Wu

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ASSESSMENT OF UNCERTAINTY IN PLANNING AND DOSE DELIVERY OF PROTON THERAPY IN AN IROC- HOUSTON QA PHANTOM DUE TO VARIABLE CT TECHNIQUE AND PROTON ENERGY, Mattie M. McInnis

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ATP-citrate lyase links cyclin E to cellular metabolism in breast cancer, Kim Lucenay

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CANCER ASSOCIATED FIBROBLAST DERIVED ANGIOGENIC FACTOR MFAP5 IN OVARIAN CANCER PROGRESSION, SZE LEE CECILIA LEUNG

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Cancer Incidence in First and Second Degree Relatives of BRCA1 and BRCA2 Mutation Carriers, Haley Streff

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CHARACTERIZATION OF ERBB4 EXPRESSION IN OSTEOSARCOMA, Nupur Lala

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CHARACTERIZATION OF LOW DENSITY INTRACRANIAL LESIONS USING DUAL-ENERGY COMPUTED TOMOGRAPHY, Jessica L. Nute

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CHARACTERIZATION OF THE ROLES OF CARMA3 AND BCL10 IN VIRUS-TRIGGERED RIG-I/MAVS SIGNALING PATHWAY, Zhicheng Zhou Mr

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COMPUTATIONAL MODELING OF RNA-SMALL MOLECULE AND RNA-PROTEIN INTERACTIONS, Lu Chen

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Correlation Matrix Analysis Identifies Gene Signatures of Immune Cell Subsets and Their Interactions in Follicular Lymphoma, Jason R. Westin

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DEFINING THE MOLECULAR NETWORKS NECESSARY FOR THYMUS FATE AND ORGANOGENESIS, Kaitlin A. Reeh

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Detection of Genes Influencing Chronic and Mendelian Disease via Loss-Of-Function Variation, Alexander H. Li

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DETERMINING THE MECHANISMS GENERATING SOLUBLE IL-15 COMPLEXES, Scott Anthony

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DEVELOPMENTAL ORIGINS OF RENAL CONNECTING TUBULE AND COLLECTING DUCT: ROLE OF AQP2+ PROGENITOR CELLS, Lihe Chen

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DIRECT REGULATION OF APOPTOSIS BY LINEAR UBIQUTIN CHAIN ASSEMBLY COMPLEX (LUBAC) AND FEEDBACK REGULATION OF LUBAC FUNCTION BY CASPASES, Donghyun Joo

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DNA POLYMERASE θ (POLQ) AND THE CELLULAR DEFENSE AGAINST DNA DAMAGE, Matthew J. Yousefzadeh

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EFFECTS OF PHARMACOLOGICAL AND GENETIC DISRUPTION OF CHEMOKINE RECEPTOR CXCR4 IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA, Shubhchintan Randhawa

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Elucidating the role of Rumi and O-glucosylation in the Drosophila eye, Amanda Haltom

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ENHANCEMENT OF HIV PERSISTENCE BY ADIPOSE TISSUE, Jacob Couturier

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Evaluating the NCCN Clinical Criteria for Hereditary Breast and Ovarian Cancer Syndrome Genetic Testing, Caiqian Wu

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EVALUATION OF CURRENT KNOWLEDGE OF GENETICS AMONG DENTAL STUDENTS, RESIDENTS AND DENTAL HYGIENE STUDENTS, Carla McGruder

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Ex Vivo Expanded Cord Blood Natural Killer Cells as a Novel Therapeutic for Multiple Myeloma, Nina Shah

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Feasibility of Using Virtual Unenhanced Images to Replace Pre-contrast Images in Multiphase Renal CT Examinations, Dawn Olivia Popnoe

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FUNCTIONAL ANALYSIS OF SYNTHETIC GENE CIRCUITS CONTROLLING A PROTEIN PUMP IN YEAST, Junchen Diao

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FUNCTIONAL IN VIVO SCREEN IDENTIFIES PYGO2 AS A PUTATIVE GENE TO PROMOTE PROSTATE CANCER, Xiaolu Pan

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GATING MECHANISMS OF THE CANONICAL TRP CHANNEL ISOFORM TRPC4, Dhananjay P. Thakur

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GENE SET ANALYSIS OF POST-LACTATIONAL MAMMARY GLAND INVOLUTION GENE SIGNATURES IN INFLAMMATORY AND TRIPLE NEGATIVE BREAST CANCER, Arvind Bambhroliya

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GENETICS OF OBESITY IN STARR COUNTY, TEXAS MEXICAN AMERICANS, Heather M. Highland

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Germline Mutation Detection in Next Generation Sequencing Data and TP53 Mutation Carrier Probability Estimation for Li-Fraumeni Syndrome, Gang Peng

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Histone H3 K4 methylation regulates the Spindle Assembly Checkpoint through direct binding of multiple checkpoint components and Cdc20, Andria C. Schibler

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IDENTIFICATION OF FAMILIAL WILMS TUMOR PREDISPOSITION GENES USING WHOLE GENOME SEQUENCING, Timothy B. Palculict

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IDENTIFYING PROTEIN KINASE TBK1 AS A NOVEL INHIBITOR OF INTESTINAL TUMORIGENESIS, Amber L. Mathews

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IGFBP2 POTENTIATES EGFR-STAT3 SIGNALING IN GLIOMA, Yingxuan Chua

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IMPACT OF DIFFERENTIATION STATUS OF KIDNEY PROGENITORS IN WILMS TUMOR DEVELOPMENT, Le Huang

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Improving Attenuation Correction in Hybrid Positron Emission Tomography, Hua Asher Ai

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Induction of caspase-dependent death by proteasome targeted therapy in glioblastoma, Christa A. Manton

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INFLUX AND EFFLUX OF ADENINE NUCLEOTIDES FROM ERYTHROCYTES REGULATE OXYGEN TRANSPORT AND SYSTEMIC METABOLISM, William G. O'Brien III

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Investigating the Interaction of AURKA and UBE2C in Colorectal Cancer Cells, Apurva M. Hegde

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INVESTIGATING THE ROLE OF CHOLESTEROL METABOLISM AND SYNTHESIS IN METASTASIS AND RADIATION RESPONSE IN AGGRESSIVE SUBTYPES OF BREAST CANCER, Adam Wolfe

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Investigating the roles of p63 and p73 isoforms to therapeutically treat p53-altered cancers, Avinashnarayan Venkatanarayan

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INVESTIGATION OF GENETIC ALTERATIONS IN EMT SUPPRESSOR, DEAR1, THROUGH PAN-CANCER ANALYSIS AND ULTRA-DEEP TARGETED SEQUENCING IN DUCTAL CARCINOMA IN SITU, Jacquelyn Reuther

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INVESTIGATION OF QUATITATIVE IMAGE FEATURES FROM PRETREATMENT CT AND FDG-PET SCANS IN STAGE III NSCLC PATIENTS UNDERGOING DEFINTIVE RADIATION THERAPY, David Fried

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INVESTIGATION OF THE ROLE OF THE SCAFFOLD PROTEIN SHC IN ERK SIGNALING, kin man suen

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IN VIVO FUNCTIONAL SIGNIFICANCE OF CCAT2 LONG NON-CODING RNA IN MYELODYSPLASTIC SYNDROME, MAITRI Y. SHAH

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IN VIVO SIGNIFICANCE OF THE MDM4 AND P73 INTERACTION DURING DEVELOPMENT AND TUMORIGENESIS, Mehrnoosh Tashakori

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Isoform Selective Regulation of Adenylyl Cyclase by Small Molecule Inhibitors and Gbetagamma Protein, Cameron S. Brand

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KNOWLEDGE AND SELF-ESTEEM IN INDIVIDUALS WITH NEUROFIBROMATOSIS TYPE 1 (NF1), Kayla Vaughn

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MEASURING SINGLE CELL RESPONSES TO LAPATINIB IN A HETEROGENEOUS POPULATION, Preety Priya

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MERLIN MEDIATED REGULATION OF HAIR FOLLICLE MORPHOGENESIS, Megan K. Fentress

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Metabolic profiling of prions in the gastro-intestinal tract, Uffaf Khan

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Methylation of EGFR by Arginine Methyltransferase PRMT1 Enhances EGFR Signaling and Cetuximab resistance, Hsin-Wei Liao

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MICRORNA-200 REGULATES ECM-DEPENDENT β1-INTEGRIN/FAK SIGNALING AND CANCER CELL INVASION, Christin Ungewiss

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Mobilization of Adipose Stromal Cells in Obesity and Cancer by SPARC and its Proteolytic Isoforms, Chieh Tseng

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MOLECULAR REGULATION OF VASCULAR CALCIFICATION IN MURINE MODELS OF ATHEROSCLEROSIS, Shanshan Gao

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MULTILEVEL DEREGULATION OF SURVIVAL MECHANISMS IN NPM-ALK+ T-CELL LYMPHOMA, Deeksha Vishwamitra

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NEW INSIGHTS ON THE ROLE OF JMJD2A IN CANCER PROGRESSION, Yuan Gao

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NFAT1 CONTRIBUTES TO MELANOMA TUMOR GROWTH AND METASTASIS BY REGULATING IL-8 AND MMP-3, Einav Shoshan

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Normal Glycolytic Enzyme Activity is Critical for Hypoxia Inducible Factor-1a Activity and Provides Novel Targets for Inhibiting Tumor Growth, Geoffrey Grandjean PhD

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Obstetrician and Gynecologist Utilization of the NIPT Expanded Testing Option, Sarah Mayes BA

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Oxidative protein folding pathways in Gram-positive Actinobacteria, Melissa E. Robinson

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PLASMACYTOID DENDRITIC CELL-MEDIATED HUMORAL AUTOIMMUNITY, Stephanie M. Dorta-Estremera Ph.D.

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POST-TRANSLATIONAL REGULATION OF ZEB1 CONTRIBUTES TO TGFβ-MEDIATED EMT, Roxsan Manshouri

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Prediction of Laser Ablation in Brain: Sensitivity, Calibration, and Validation, Samuel J. Fahrenholtz

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PREVENTING THYMUS INVOLUTION IN K5.CYCLIN D1 TRANSGENIC MICE SUSTAINS THE NAÏVE T CELL COMPARTMENT WITH AGE, Michelle L. Bolner

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Prophylactic Cranial Irradiation Reduces the Incidence of Brain Metastasis in a Mouse Model of Metastatic Breast Cancer, Daniel L. Smith

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QUALITY ASSURANCE OF ADVANCED TREATMENT MODALITIES USING PRESAGE® DOSIMETERS, Ryan G. Lafratta

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Quantification of IMRT severity scores for improvement of FMEA results, Jacqueline T. Faught

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REDIRECTING T CELLS WITH CHIMERIC ANTIGEN RECEPTORS TO TARGET CD123+ LEUKEMIA, Radhika Thokala

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REDUCTION OF DOSE CALCULATION ERRORS FOR PATIENTS WITH METAL IMPLANTS RECEIVING PHOTON RADIATION THERAPY, Jessie Huang-Vredevoogd

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Regulation of Autoimmune Germinal Center Reaction by Tfh Cells and Application of Tfr-like Cells for the Treatment of Autoimmune B Cell Responses, Young Uk Kim

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Regulation of Cell Adhesion by the FERM Proteins, PTPN14 and Merlin, Patty Dimarco Hewitt

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REGULATION OF THE OXIDATIVE STRESS RESPONSE BY ARID1A, Suet Yan Kwan

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REST REGULATORY CIRCUIT CONTROLS DISTINCT ONCOGENIC PROPERTIES OF GLIOBLASTOMA STEM CELLS THROUGH SPECIFIC MICRORNAs, Anantha L Marisetty

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ROLE OF STAT3 IN HUMAN NK CELL FUNCTIONS, Prasad V. Phatarpekar

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SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS: IN SUPPORT OF TRANSLATIONAL THERAPY, David Rushworth

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SERUM OMENTIN AS A POTENTIAL BIOMARKER FOR COMPLEX ATYPICAL HYPERPLASIA AND ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA, Laura L. Holman MD

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SOCIAL-DEMOGRAPHICS, HEALTH BEHAVIORS, TELOMERE LENGTH IN MEXICAN-AMERICAN COHORT AND CIRCULATING DNA METHYLATION IN BLADDER CANCER, Lixia Han

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Spiritual Exploration in the Prenatal Genetic Counseling Session, Katelynn G. Sagaser

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SRC HOMOLOGY 2 DOMAIN-CONTAINING 5’-INOSITOL PHOSPHATASE-2 (SHIP2) IS AN EFFECTOR OF LYMPHATIC DYSFUNCTION, Germaine D. Agollah

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Structure and Composition of Postsynaptic Densities, Madeline Farley

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SUNITINIB-INDUCED CARDIOTOXICITY EXPOSES MICROVASCULAR AND METABOLIC DERANGEMENTS IN THE FAILING HEART, Meredith R. Rodriguez

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SYNTHETIC LETHALITY OF CDK INHIBITION AND DOXORUBICIN IN TRIPLE-NEGATIVE BREAST CANCER REQUIRES P53 INACTIVATION, Natalie A. Jabbour-Leung

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TARGETED INHIBITION OF PI3K, MTOR, AND IGF1R FOR THE TREATMENT OF UNDIFFERENTIATED PLEOMORPHIC SARCOMA, Caitlin Denise May

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Targeting An Ancient Retrovirus During Melanoma Using Adoptive T Cells Therapy, janani Krishnamurthy

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Targeting oncogenic miRNAs with Small Molecules for Breast Cancer Therapy, Paloma del C. Monroig

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Texas Physicians' Awareness and Utilization of Genetic Services, Callie L. Jenevein

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THE EFFECT OF ACTIVATION INDUCED CYTIDINE DEAMINASE PHOSPHORYLATION AND HERPES VIRUS URACIL DNA GLYCOSYLASE ON ANTIBODY DIVERSIFICATION, Marc Macaluso

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THE EFFECT OF ROOM ENVIRONMENT ON PATIENT EXPERIENCE IN A PRENATAL GENETIC COUNSELING SESSION, Elizabeth C. Baack

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THERMAL ABLATION ALTERS THE TUMOR MICROENVIRONMENT ACTIVATING A ROBUST IMMUNE RESPONSE., Matthew T. Campbell M.D.

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THE ROLE OF AUTOPHAGY IN THE SENSITIVITY OF OSTEOSARCOMA CELLS TO GEMCITABINE TREATMENT, Janice M. Santiago-O'Farrill

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The role of DNA methylation and hydroxymethylation in smooth muscle cell phenotypic change during atherogenesis, jason Williams

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The Structural Mechanism of Allosteric Modulation of the NMDA Receptor: A Balance of Tensions, Rita E. Sirrieh

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THE TUMOR SUPPRESSOR NOTCH INHIBITS HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) TUMOR GROWTH AND PROGRESSION BY MODULATING PROTO-ONCOGENES AXL AND CTNNAL1 (α-CATULIN), Shhyam Moorthy and Shhyam Moorthy

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TRIM28 INTERACTS WITH EZH2 TO REGULATE ITS ACTIVITY, Jing Li and Jing Li

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TWO-COLOR FLUORESCENT ANALYSIS OF CONNEXIN 36 TURNOVER AND TRAFFICKING – RELATIONSHIP TO FUNCTIONAL PLASTICITY, Yanran Wang

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UNDERSTANDING THE ROLE OF SUMOYLATION IN REGULATING LKB1 FUNCTION, Joan W. Ritho

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VOXEL-LEVEL ABSORBED DOSE CALCULATIONS WITH A DETERMINISTIC GRID-BASED BOLTZMANN SOLVER FOR NUCLEAR MEDICINE AND THE CLINICAL VALUE OF VOXEL-LEVEL CALCULATIONS, Justin Mikell

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YAP1 expression predicts sensitivity to dual AKT/P70S6K inhibition in ovarian and uterine malignancies, Rebecca A. Previs