Open Access full-text copies of the UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Older UT GSBS dissertations (approximately 1979-1999) are available in print-format only and are available in the The TMC Library. They're listed in the Library Catalog under the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

Some older full-text dissertations are also available via ProQuest but access to this database is restricted to the TMC community.

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Theses/Dissertations from 2015

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DEFINING THE MOLECULAR NETWORKS NECESSARY FOR THYMUS FATE AND ORGANOGENESIS, Kaitlin A. Reeh

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INVESTIGATION OF GENETIC ALTERATIONS IN EMT SUPPRESSOR, DEAR1, THROUGH PAN-CANCER ANALYSIS AND ULTRA-DEEP TARGETED SEQUENCING IN DUCTAL CARCINOMA IN SITU, Jacquelyn Reuther

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UNDERSTANDING THE ROLE OF SUMOYLATION IN REGULATING LKB1 FUNCTION, Joan W. Ritho

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Oxidative protein folding pathways in Gram-positive Actinobacteria, Melissa E. Robinson

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SUNITINIB-INDUCED CARDIOTOXICITY EXPOSES MICROVASCULAR AND METABOLIC DERANGEMENTS IN THE FAILING HEART, Meredith R. Rodriguez

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SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS: IN SUPPORT OF TRANSLATIONAL THERAPY, David Rushworth

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Spiritual Exploration in the Prenatal Genetic Counseling Session, Katelynn G. Sagaser

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THE ROLE OF AUTOPHAGY IN THE SENSITIVITY OF OSTEOSARCOMA CELLS TO GEMCITABINE TREATMENT, Janice M. Santiago-O'Farrill

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Histone H3 K4 methylation regulates the Spindle Assembly Checkpoint through direct binding of multiple checkpoint components and Cdc20, Andria C. Schibler

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IN VIVO FUNCTIONAL SIGNIFICANCE OF CCAT2 LONG NON-CODING RNA IN MYELODYSPLASTIC SYNDROME, MAITRI Y. SHAH

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Ex Vivo Expanded Cord Blood Natural Killer Cells as a Novel Therapeutic for Multiple Myeloma, Nina Shah

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NFAT1 CONTRIBUTES TO MELANOMA TUMOR GROWTH AND METASTASIS BY REGULATING IL-8 AND MMP-3, Einav Shoshan

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The Structural Mechanism of Allosteric Modulation of the NMDA Receptor: A Balance of Tensions, Rita E. Sirrieh

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Prophylactic Cranial Irradiation Reduces the Incidence of Brain Metastasis in a Mouse Model of Metastatic Breast Cancer, Daniel L. Smith

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Cancer Incidence in First and Second Degree Relatives of BRCA1 and BRCA2 Mutation Carriers, Haley Streff

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INVESTIGATION OF THE ROLE OF THE SCAFFOLD PROTEIN SHC IN ERK SIGNALING, kin man suen

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IN VIVO SIGNIFICANCE OF THE MDM4 AND P73 INTERACTION DURING DEVELOPMENT AND TUMORIGENESIS, Mehrnoosh Tashakori

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GATING MECHANISMS OF THE CANONICAL TRP CHANNEL ISOFORM TRPC4, Dhananjay P. Thakur

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REDIRECTING T CELLS WITH CHIMERIC ANTIGEN RECEPTORS TO TARGET CD123+ LEUKEMIA, Radhika Thokala

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Mobilization of Adipose Stromal Cells in Obesity and Cancer by SPARC and its Proteolytic Isoforms, Chieh Tseng

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MICRORNA-200 REGULATES ECM-DEPENDENT β1-INTEGRIN/FAK SIGNALING AND CANCER CELL INVASION, Christin Ungewiss

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KNOWLEDGE AND SELF-ESTEEM IN INDIVIDUALS WITH NEUROFIBROMATOSIS TYPE 1 (NF1), Kayla Vaughn

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Investigating the roles of p63 and p73 isoforms to therapeutically treat p53-altered cancers, Avinashnarayan Venkatanarayan

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MULTILEVEL DEREGULATION OF SURVIVAL MECHANISMS IN NPM-ALK+ T-CELL LYMPHOMA, Deeksha Vishwamitra

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TWO-COLOR FLUORESCENT ANALYSIS OF CONNEXIN 36 TURNOVER AND TRAFFICKING – RELATIONSHIP TO FUNCTIONAL PLASTICITY, Yanran Wang

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Correlation Matrix Analysis Identifies Gene Signatures of Immune Cell Subsets and Their Interactions in Follicular Lymphoma, Jason R. Westin

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The role of DNA methylation and hydroxymethylation in smooth muscle cell phenotypic change during atherogenesis, jason Williams

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INVESTIGATING THE ROLE OF CHOLESTEROL METABOLISM AND SYNTHESIS IN METASTASIS AND RADIATION RESPONSE IN AGGRESSIVE SUBTYPES OF BREAST CANCER, Adam Wolfe

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Evaluating the NCCN Clinical Criteria for Hereditary Breast and Ovarian Cancer Syndrome Genetic Testing, Caiqian Wu

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ANKYRIN-B AND mTOR COMPLEX 1 IN THE REGULATION OF ELECTRICAL ACTIVITIES IN THE HEART, Henry C. Wu and Henry C. Wu

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DNA POLYMERASE θ (POLQ) AND THE CELLULAR DEFENSE AGAINST DNA DAMAGE, Matthew J. Yousefzadeh

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CHARACTERIZATION OF THE ROLES OF CARMA3 AND BCL10 IN VIRUS-TRIGGERED RIG-I/MAVS SIGNALING PATHWAY, Zhicheng Zhou Mr

Theses/Dissertations from 2014

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Functional Analysis of Cytosolic Hsp70 Nucleotide Exchange Factor Networks in Yeast, Jennifer Lynn Abrams

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Effects of oxytocin on human aggression, Joseph L. Alcorn III

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DUAL ASSEMBLY NANOPARTICLES ACHIEVE SUSTAINED SILENCING OF ZNF304: A NOVEL TRANSCRIPTION FACTOR FOR Β1 INTEGRIN, Burcu Aslan

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DEVELOPMENT OF CHIMERIC TYPE IV SECRETION SYSTEMS FOR TRANSFER OF HETEROLOGOUS SUBSTRATES ACROSS THE GRAM-NEGATIVE CELL ENVELOPE, Trista M. Berry

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TARGETING THE MDM2-P53 AXIS FOR THE TREATMENT OF DEDIFFERENTIATED LIPOSARCOMA, Katelynn Bill

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Methodological Development of a Multi-Parametric Quantitative Imaging Biomarker Framework for Assessing Treatment Response with MRI, Ryan J. Bosca

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REGULATION OF FUNCTIONAL EXPRESSION OF MECHANOSENSITIVE TRPV4 CHANNEL IN THE DISTAL NEPHRON BY DIETARY POTASSIUM AND SODIUM INTAKE, Nabila Boukelmoune

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THE ONCOGENIC MAP KINASE SIGNALING PATHWAY MODULATES MHC-I SURFACE EXPRESSION IN MELANOMA, Sherille Denae Bradley

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PI3K- and mTOR-dependent mechanisms of lapatinib resistance and resulting therapeutic opportunities, Samuel Brady

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NO-INDEPENDENT MODULATION OF SOLUBLE GUANYLYL CYCLASE (sGC) ACTIVITY AND FUNCTION, George L. Britton Jr

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Mapping the Human Vasculature by In Vivo Phage Display, Julianna Bronk

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Anti-GD2 Etoposide-Loaded Immunoliposomes for the Treatment of GD2 Positive Tumors, Brandon S. Brown

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ROLES FOR B-Raf KINASE IN THE SPECIFIC REGULATION OF α4β1 INTEGRIN IN T CELLS, Wells S. Brown

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CHARACTERIZATION OF FTSA-FTSN INTERACTION DURING ESCHERICHIA COLI CELL DIVISION, kimberly.busiek@gmail.com K. Busiek

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THE ROLE OF THE C5A RECEPTOR IN HOST DEFENSE AGAINST LISTERIA MONOCYTOGENES, Daniel Calame

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CAR-MODIFIED T CELLS CAPABLE OF DISTINGUISHING NORMAL CELLS FROM MALIGNANT CELLS, Hillary G. Caruso

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IMBALANCE BETWEEN NEUTROPHIL ELASTASE AND ELAFIN PROMOTES BREAST CANCER GROWTH AND PROGRESSION, Joseph Anthony Caruso

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ACTIVATING THE 4-1BB PATHWAY FOR THE EXPANSION OF TUMOR-INFILTRATING LYMPHOCYTES FOR ADOPTIVE T-CELL THERAPY FOR METASTATIC MELANOMA PATIENTS, Jessica Ann Chacon

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ACTIVATING THE 4-1BB PATHWAY FOR THE EXPANSION OF TUMOR-INFILTRATING LYMPHOCYTES FOR ADOPTIVE T-CELL THERAPY FOR METASTATIC MELANOMA PATIENTS, Jessica Ann Chacon

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ROLE OF PHOSPHORYLATION OF FOCAL ADHESION KINASE AT TYROSINE 861 IN PROSTATE CANCER METASTASIS, Tanushree Chatterji

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MECHANISMS UNDERLYING DISTINCT EGFR VERSUS FGFR-3 AND -1 DEPENDENCY IN HUMAN BLADDER CANCER CELLS, Tiewei Cheng

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QUANTITATIVE ANALYSIS AND IMAGING-BASED INSIGHTS INTO THE CHARACTERISTICS AND MECHANISMS OF YEAST PATTERN FORMATION, LIN CHEN

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NUCLEAR TRANSLOCATION OF MET VIA INTERNET MECHANISM, MEI-KUANG CHEN

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Image-Guided Proton Therapy for Online Dose-Evaluation and Adaptive Planning, Joey P. Cheung

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USE OF POSITRON EMISSION TOMOGRAPHY FOR PROTON THERAPY VERIFICATION, Jongmin Cho

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ANTI-INSULIN RESISTANCE TREATMENTS SUPPRESS HER2+ BREAST CANCER GROWTH VIA ALTERING METABOLISM, PING-CHIEH CHOU

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SYSTEMATIC METHODOLOGY FOR THE IDENTIFICATION OF A NOVEL AUTOSOMAL DOMINANT RETINITIS PIGMENTOSA DISEASE-CAUSING GENE, Jennifer D. Churchill

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p53 MAINTAINS HEPATIC CELL IDENTITY DURING LIVER REGENERATION, Zeynep Hande Coban Akdemir

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ENERGY STRESS CAUSES CHAPERONES TO ASSEMBLE INTO CYTOPLASMIC COMPLEXES, Kimberly J. Cope

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ROLE OF THE ANG-TIE2 PATHWAY IN THE INVASIVE RECURRENCE OF GBM FOLLOWING ANTI-VEGF THERAPY, Nahir Cortes Santiago

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CD56-SPECIFIC T CELLS: USING GENETICALLY ENGINEERED T CELLS TO REDIRECT SPECIFICITY TO A T CELL EXPRESSED ANTIGEN, Denise L. Crossland

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ROLE OF MACROPHAGES IN ADAPTIVE RESISTANCE TO ANTI-VEGF THERAPY, Heather Dalton

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GENETIC PREDICTORS OF METABOLIC SIDE EFFECTS OF DIURETIC THERAPY, Jorge L. Del Aguila

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Change Detection in Rhesus Monkeys and Humans, Deepna T. Devkar and Deepna T. Devkar

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EYE-TRACKING MEASURES OF ATTENTIONAL BIAS IN COCAINE DEPENDENT SUBJECTS, Nadeeka Dias

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Gain-of-function Mouse Models to Investigate Biological Roles of PRMT6, Alessandra Di Lorenzo

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EFFECTS OF RESTING STATE ON PERCEPTUAL LEARNING, Sarah Eagleman Ph.D.

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Development of a New Independent Monte Carlo Dose Calculation Quality Assurance Audit Tool for Clinical Trials, Austin M. Faught

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Investigating the Role of Exosomal Communication in the Glioma Microenvironment, Javier Figueroa

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REACTIVE OXYGEN SPECIES AND P21 WAF1/CIP1 ARE BOTH ESSENTIAL FOR, Alison Fitzgerald

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INVESTIGATING CHECKPOINT KINASES 1/2 AS NOVEL THERAPEUTIC TARGETS IN HEAD AND NECK SQUAMOUS CELL CARCINOMA, MAYUR ARVIND GADHIKAR

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The Role of MIR-34a in Inhibition of Prostate Tumor Growth in the bone and Induction of Autophagy, Sanchaika Gaur

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NOTCH SIGNALING INHIBITED BY IKAROS1 IN HUMAN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA, Camille W. Graham

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COMBINATION THERAPY WITH AEROSOL IL-2 AND NK CELLS FOR THE TREATMENT OF OSTEOSARCOMA LUNG METASTASIS, Sergei R. Guma

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THE ROLE OF GLUTAMINE AND MEVALONATE PATHWAY IN AFFECTING THE STEMNESS AND VIABILITY OF GLIOBLASTOMA STEM CELLS, Naima Hammoudi

Anchoring and Uptake of Non-Invasive Prenatal Testing in the First and Second Trimester, Amanda S. Hanson

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FUNCTIONS OF THE HOMEOBOX GENE DLX4 IN CONTROLLING INFLAMMATORY SIGNALING AND METASTASIS OF EPITHELIAL OVARIAN CANCER, Dhwani Haria

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SOX2-DEPENDENT TRANSCRIPTIONAL CONTROL OF AIRWAY DIFFERENTIATION IN THE MOUSE LUNG, Belinda J. Hernandez

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Regulators of Bacterial Cell Division: Investigations of Min Oscillation and FtsA Activity, Jennifer R. Herricks

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STRUCTURE BASED PREDICTION OF DRUG-PROTEIN INTERACTIONS AT ALLOSTERIC SITES: TOWARDS DIRECT INHIBITION OF THE RAS ONCOGENE, Harrison Hocker

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Implementation of Upright Treatments for Lung and Head and Neck Cancers, Ming-Jung Hsieh

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MODULATED FUNCTIONS OF THE FANCONI ANEMIA CORE COMPLEX, Yaling Huang

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TETHERED IL-15 TO AUGMENT THE THERAPEUTIC POTENTIAL OF T CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTOR: MAINTAINING MEMORY POTENTIAL, PERSISTENCE, AND ANTITUMOR ACTIVITY, Lenka Hurton

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Characterization of the New Xoft Axxent Electronic Brachytherapy Source Using PRESAGE(TM), Jennifer Sierra Irwin

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THE ROLE OF TRAF6 PHOSPHORYLATION IN Src/TRAF6-MEDIATED IKK, JNK, Akt ACTIVATION AND TUMORIGENESIS, Yun Seong Jeong

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Regulation of the Candida albicans arginine biosynthetic pathway, Claudia Jimenez Lopez

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ROLE OF TALIN1 PHOSPHORYLATION IN BETA1 INTEGRIN ACTIVATION AND PROSTATE CANCER METASTASIS, Jung-Kang Jin

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EPIDERMAL GROWTH FACTOR RECEPTOR INDUCES FYN EXPRESSION VIA UP-REGULATION OF P47PHOX IN GLIOBLASTOMA MULTIFORME, Blake P. Johnson

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EVALUATION OF ARTIFACTS IN EXPERIMENTAL CINE 4D CT ACQUISITION METHODS, Sarah Joy

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IDENTIFICATION OF CELL SIGNALING PATHWAY REGULATED BY MICRORNAS IN CANCER CELLS USING A SYSTEMS BIOLOGICAL APPROACH, sangbae Kim

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THE EPIGENETICS OF SMALL CELL PROSTATE CANCER, Brittany N. Kleb

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MULTIPLE MYELOMA AND ITS TREATMENT ALTER PERIPHERAL NERVOUS SYSTEM STRUCTURE AND FUNCTION, Alyssa K. Kosturakis

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NATURAL AND EXOGENOUS GENOME EDITING IN WISKOTT-ALDRICH SYNDROME PATIENT CELLS, Tamara J. Laskowski

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PANCREATIC RIBONUCLEASE FUNCTIONS AS AN EPIDERMAL GROWTH FACTOR RECEPTOR LIGAND INDEPENDENTLY OF ITS ENZYME ACTIVITY AND CONTRIBUTES TO CETUXIMAB RESISTANCE, Heng-Huan Lee

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TYROSINE 370 PHOSPHORYLATION OF ATM POSITIVELY REGULATES DNA DAMAGE RESPONSE, Hong-Jen Lee

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p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiation, moonsup lee

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Novel Posttranslational Modification in LKB1 Activation and Function, Szu-Wei Lee

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CONTRIBUTION OF INTERLEUKIN 6 TRANS SIGNALING IN PULMONARY FIBROSIS, Thuy T. Le