Open-access, full-text copies of The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.

Older GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.

Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.

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Theses/Dissertations from 2020

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Investigating the role of Quaking in antigen uptake and cross-presentation by dendritic cells, Yating Li

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INVESTIGATION OF PROLIFERATION SUPPRESSORS IN GENETIC FITNESS SCREENS, Walter Frank Lenoir IV

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INVESTIGATION OF THE FUNCTIONAL IMPACT OF ANTI-PD-1 ON TUMOR-INFILTRATING LYMPHOCYTES (TIL) AND MAPPING OF TUMOR GENOMIC FEATURES RELEVANT FOR RESPONSE TO TIL THERAPY, Caitlin Creasy

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IONIC MECHANISM OF LYSOSOMAL FUNCTION AND CELL METABOLISM, Jian Xiong

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LONGITUDINAL CLONAL LINEAGE DYNAMICS AND FUNCTIONAL CHARACTERIZATION OF PANCREATIC CANCER CHEMO-RESISTANCE AND METASTASIZATION, Chieh-Yuan Li

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LOSS OF CASPASE-8 FUNCTION IN COMBINATION WITH SMAC MIMETIC TREATMENT SENSITIZES HEAD AND NECK SQUAMOUS CARCINOMA TO RADIATION THROUGH INDUCTION OF NECROPTOSIS., Burak Uzunparmak

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MCP-1 Release Modulation Through Interaction of Pulmonary Endothelial Cells and Mesenchymal Stromal Cells, Kaavya Giridhar

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Mechanistic Insights into Vancomycin Resistance in Clostridioides difficile, Ayesha Mahmood

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METHODS TO INVESTIGATE HYPERTHERMIA INDUCED BY TUMOR TREATING FIELDS, Ruchi Singh

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MICRORNAs ASSOCIATED WITH MELANOMA INFLAMMATION AND RESPONSE TO PD-1 INHIBITION, Robert Szczepaniak Sloane

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Modulating Avidity of h8F4-CAR by Regulation of Expression via Codon Modification, Rolando Vedia

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MODULATION OF PI3K-AKT PATHWAY IN COLORECTAL CANCER, Maliha Nusrat

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MOLECULAR MECHANISMS OF ANTIMICROBIAL RESISTANCE IN MULTI-DRUG RESISTANT ENTEROCOCCI, Ayesha Khan

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MULTIPLEXED CRISPR LIBRARIES FOR CANCER FUNCTIONAL GENOMICS, Jintan Liu

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Mutations Within and Between Early Cell Division Proteins and Their Effects on Division Regulation in Escherichia coli, Kara Schoenemann

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Nuclear-targeted gold nanoparticles enhance the effects of radiation therapy with and without liposomal delivery, Maureen Aliru

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p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo, Sydney Moyer

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PACKAGING AND SECRETION OF AIRWAY MUCINS, Oanh Ngoc Hoang

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PRECLINICAL STUDIES OF A NOVEL IDH1 INHIBITOR IN ACUTE MYELOID LEUKEMIA (AML), Vivian Salama

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PUTATIVE ROLES OF CD200 IN THE LEUKEMOGENESIS AND IMMUNE EVASION OF LEUKEMIA STEM CELLS, Shelley Herbrich

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QKI-MEDIATED CHOLESTEROL BIOSYNTHESIS IN EYE LENS AND MYELIN OF THE CENTRAL NERVOUS SYSTEM, Seula Shin and Seula Shin

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QKI-MEDIATED CHOLESTEROL BIOSYNTHESIS IN EYE LENS AND MYELIN OF THE CENTRAL NERVOUS SYSTEM, Seula Shin and Seula Shin

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RECEPTOR TYROSINE KINASES-MEDIATED ACQUIRED PARP INHIBITOR RESISTANCE IN BREAST CANCER, MEI-KUANG CHEN

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REVERSAL OF NEURODEGENERATION BY ENGINEERED MONOCYTES IN ALZHEIMER’S DISEASE, Chao-Hsien Chen

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SINE OCULIS HOMEOBOX HOMOLOG 1 (SIX1) PLAYS A CRITICAL ROLE IN THE PROGRESSION OF PULMONARY FIBROSIS., Cory Wilson

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Statistical Methods for Resolving Intratumor Heterogeneity with Single-Cell DNA Sequencing, Alexander Davis

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Subclonal evolution of chronic lymphocytic leukemia after allogeneic T cell therapies, Haven Garber

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TARGETING UNIQUE DOMAINS OF LSD1 REGULATES PEDIATRIC GLIOMA INNATE IMMUNITY AND NK CELL METABOLISM, Cavan Bailey

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THE COURSE OF ACUTE STRESS DISORDER AND POST TRAUMATIC STRESS DISORDER IN PARENTS WITH INFANTS IN THE NEONATAL INTENSIVE CARE UNIT, Caroline Bertsch

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The Genome-Wide Roles of the Lung Lineage Transcription Factor NKX2-1 in the Regulation of Opposing Cell Fates In Vivo, Danielle Renae Little

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THE ROLE OF DAAM1 IN KIDNEY DEVELOPMENT, vanja krneta-stankic

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THE ROLE OF DAAM1 IN KIDNEY DEVELOPMENT, vanja krneta-stankic

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UNDERSTANDING INTERCELLULAR SIGNALING DURING LUNG INJURY-REPAIR, Margo Patricia Cain

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Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers, Sherille Denae Bradley

Theses/Dissertations from 2019

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An Information Theory Model for Optimizing Quantitative Magnetic Resonance Imaging Acquisitions, Drew Mitchell

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A NOVEL SWITCH-LIKE FUNCTION OF DELTA-CATENIN IN DENDRITE DEVELOPMENT, Ryan Baumert

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AN OXANTHROQUINONE DERIVATIVE DISRUPTS RAS PLASMA MEMBRANE LOCALIZATION AND FUNCTION BY INHIBITION OF ACYLPEPTIDE HYDROLASE AND PERTURBATION OF SPHINGOMYELIN METABOLISM, Lingxiao Tan

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A SIGNATURE ENRICHMENT DESIGN WITH BAYESIAN ADAPTIVE RANDOMIZATION FOR CANCER CLINICAL TRIALS, Fang Xia

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ASSESSMENT OF NEW INNOVATIONS IN PET/CT FOR RESPIRATORY MOTION CORRECTION, Joseph Meier

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Bilirubin Nanoparticle as an Anti-Inflammatory Therapy for Graft versus Host Disease, Sumedha Pareek

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Commissioning of Micro-Cube Thermoluminescent Dosimeters for Small Field Dosimetry Quality Assurance in Radiotherapy, Brandon Luckett

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COMPUTATIONAL GENOMIC MODELS FOR SPATIO-TEMPORAL INVESTIGATION OF EARLY LUNG CANCER PATHOLOGY, Smruthy Sivakumar

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Cross-presentation Is A Source of Tumor Antigens For Multiple Myeloma Immunotherapy, Alexander A. Perakis

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Current Practices and Perspectives of Genetic Counselors and Reproductive Endocrinologists Regarding Transfer of Mosaic Embryos, Angelica Starnes

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Deconvolute brain tumor genomic alterations based on DNA methylation, Jie Yang

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DETERMINATION OF THYMIC EPITHELIAL CELL COMPOSITION AND PROLIFERATION DURING THE PERINATAL TO ADULT TRANSITION, Scott Casey

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DEUBIQUITINATING ENZYMES PROMOTE CANCER PROGRESSION AND METASTASIS VIA REGULATING PROTEIN STABILITY, Zhenna Xiao

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Development of a High-Throughput System for Screening of Anti-Prion Molecules, Katherine Do

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DEVELOPMENT OF AUTOMATED RADIOTHERAPY TREATMENT PLANNING FOR CERVICAL AND BREAST CANCER FOR RESOURCE-CONSTRAINED CLINICS, Kelly Kisling

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DHHC5 REGULATES BETA-ADRENERGIC SIGNALING IN THE HEART THROUGH PALMITOYLATION OF G ALPHA PROTEINS, Jie Chen

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DISSECTING THE ROLES OF HUMAN SMC COMPLEXES IN TRANSCRIPTION REGULATION AND CHROMATIN ORGANIZATION, Ruoyu Wang

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Endosomal Trafficking and Exosomal Secretion Of EGFRvIII, Kimiya Memarzadeh

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Evaluating the therapeutic efficacy of Grb2 inhibition in ovarian malignancies, Olivia Lara

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Exploring Experiences & Expectations of Prenatal Healthcare and Genetic Counseling/Testing in Immigrant Latinas, Georgiann Garza

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EXPLORING THE POTENTIAL YIELD OF PRENATAL TESTING BY EVALUATING A POSTNATAL POPULATION WITH STRUCTURAL ABNORMALITIES, Peyton Busby

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FASTING REDUCES INTESTINAL RADIOTOXICITY ENABLING DOSE-ESCALATED RADIOTHERAPY FOR PANCREATIC CANCER, Marimar de la Cruz Bonilla

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GCN5 Loss Impacts MYC-Driven Cancer in Mice and Human Cells, Aimee Farria

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GENETIC COUNSELOR UTILIZATION AND INTERPRETATION OF SOMATIC TUMOR TESTING IN EVALUATION FOR LYNCH SYNDROME, Danielle Williams

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Higher order chromosome organization and recombination dynamics of meiotic prophase I in mouse spermatocytes, Rhea Kang

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Hsp70-mediated regulation of Hsf1 transcriptional activity in Saccharomyces cerevisiae, Sara Peffer

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Hypoglycemia in Mitochondrial Disorders, Allison Moats

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Identification And Molecular Analysis Of DNA In Exosomes, Jena Tavormina

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Identifying and Targeting Adaptive Changes to BET Inhibition in Ovarian Cancer, Christopher LaFargue

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Identifying Interest in and Barriers to Psychiatric Genetic Counseling, Samantha Montgomery

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Identifying Pathogenic Variants in Hereditary Cancer Syndrome Genes via Tumor Molecular Profiling, Carol Nowlen

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IL-6/JAK1 DRIVES PD-L1 PHOSPHORYLATION AND GLYCOSYLATION TO PROMOTE CANCER IMMUNE EVASION, Li-Chuan Chan

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INHIBITION OF UROTHELIAL CARCINOMA BY TYPE I INTERFERON ACTIVATION OF THE INNATE AND ADAPTIVE IMMUNE RESPONSE, Devin Plote

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Investigating the role of CD109 in Pancreatic Ductal Adenocarcinoma, MennatAllah Shaheen

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INVESTIGATING THE ROLE OF THE P63 ISOFORM ΔNP63 IN LUNG STEM CELL POPULATIONS AND LUNG CANCER, Sarah J. Wu

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INVESTIGATIONS OF THE STRUCTURE-FUNCTION RELATIONSHIP IN KAINATE RECEPTORS USING FÖRSTER RESONANCE ENERGY TRANSFER, Douglas Litwin

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IPSC BASED GENE CORRECTION AND DISEASE MODEL OF A NEW CLASS OF LGMD DUE TO POGLUT1 MUTATION, Jose Ortiz-Vitali

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Metabolic Control, Quality of Life, and Body Image in Patients with Glycogen Storage Disease Type Ia, Alexa Bream

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MODELING CANCER USING LI-FRAUMENI SYNDROME PATIENT-DERIVED INDUCED PLURIPOTENT STEM CELLS, Ruoji Zhou

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Modeling Proton Relative Biological Effectiveness Using Monte Carlo Simulations of Microdosimetry, Mark A. Newpower

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MOLECULAR CONSEQUENCES OF HIGH TAZ EXPRESSION IN GLIOMAS, Visweswaran Ravikumar

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MULTIMODALITY SOMATOSTATIN ANALOG FOR FLUORESCENCE-GUIDED SURGERY IN CANCER, Servando Hernandez Vargas

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OBSCURIN MEDIATES ANKYRIN COMPLEX FORMATION IN THE HEART, Janani Subramaniam

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Oxidative Phosphorylation: A Critical Feature and Novel Therapeutic Target in Melanoma Brain Metastases, Grant Fischer

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P53R245W MUTATION ELICITS METASTATIC PHENOTYPE IN PTEN DEFICIENT PROSTATE CANCER, Ky Pham

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PLATISCITY OF C. ELEGANS GERMLINE STEM CELLS UNDER NUTRITIONAL AND METABOLIC STRESS, Kenneth Trimmer

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QUANTIFYING UNCERTAINTY IN A MEASUREMENT-BASED ASSESSMENT OF RELATIVE BIOLOGICAL EFFECTIVENESS IN CARBON ION RADIOTHERAPY, Shannon Hartzell

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QUANTITATIVE IMAGING FOR PRECISION MEDICINE IN HEAD AND NECK CANCER PATIENTS, Rachel Ger

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Rejuvenation of the Epigenetic Landscape of the Aged Brain Through Manipulation of Circulating Factors, Edward Koellhoffer

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Relevance of FGFR1 and its Isoforms in Prostate Cancer Bone Metastases, Estefania Labanca

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ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER, Clinton Yam

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ROLE OF NUDT21 MEDIATED ALTERNATIVE POLYADENYLATION AND HYALURONAN IN THE DEVELOPMENT OF PULMONARY HYPERTENSION, Scott Dale Collum

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Sequence-Specific Gene Correction of Cystic Fibrosis Airway Basal Cells, Varada Anirudhan

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Termination for Fetal Anomaly: What is The Impact of Genetic Counseling on Coping?, Cayleen Smith

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THE CHARACTERIZATION OF T-CELL MANUFACTURING FOR ADOPTIVE T-CELL THERAPIES, amir ALPERT

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The effect of traumatic brain injury on tau pathology by a potential seeding mechanism, George Edwards III

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THE GSK-3β-FBXL21 AXIS REGULATES TCAP VIA UBIQUITIN-MEDIATED PROTEASOMAL PATHWAY IN THE CYTOPLASM, Jiah Yang

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The impacts of insurance and billing considerations on the practice and attitudes of genetic counselors, Emily Krosschell

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THE INFLUENCE OF THE PEP-PTS AND OTHER METABOLIC SYSTEMS ON THE MASTER VIRULENCE REGULATOR ATXA AND TOXIN GENE EXPRESSION IN BACILLUS ANTHRACIS, Naomi Bier-Reizes

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THE ROLE OF GAMMA OSCILLATIONS AND CORTICAL INHIBITION IN THE DEVELOPMENT OF WORKING MEMORY IN ADOLESCENCE, Christopher P. Walker

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THE ROLE OF GENE EXPRESSION NOISE IN MAMMALIAN CELL SURVIVAL, Kevin Farquhar

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THE ROLE OF MEMBRANE DOMAINS IN PROTEIN AND LIPID SORTING DURING ENDOCYTIC TRAFFIC, Blanca B. Diaz-Rohrer

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Thiol-based Misfolding: Linking Redox Balance to Cytosolic Proteostasis, Ford Amy

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TRACKING TREATMENT RESPONSE AND RESISTANCE TO PARP INHIBITION (TALAZOPARIB) IN HEREDITARY PANCREATIC CANCER., Jennifer Goldstein

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Uncovering the ZEB1 Interactome to Identify Novel Regulators of Metastatic Non-small Cell Lung Cancer, Roxsan Manshouri

Theses/Dissertations from 2018

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3D SCINTILLATOR DETECTOR QUENCHING CHARACTERIZATION FOR SCANNING PROTON BEAMS, Fahed Alsanea