Open-access, full-text copies of UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.

Older UT GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.

Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.

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Theses/Dissertations from 2017

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Barriers to Expansion of Supervision Networks at Genetic Counseling Training Programs, Jordan E. Berg

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CD47+ Exosomes Facilitate Effective Targeting of Oncogenic Kras in Pancreatic Cancer, Sushrut Kamerkar

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CHARACTERIZATION AND REVERSAL OF DOXORUBICIN-MEDIATED CHANGES IN SENSORY NEURONS, Brittany L. Coughlin

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CHARACTERIZATION OF NOTCH1 AND PI3K-PTEN-AKT/mTOR PATHWAY INTERACTION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA, Kyriante' Henry

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CHARACTERIZATION OF THE ROLE OF THE pKM101-ENCODED T4SS OUTER MEMBRANE CORE COMPLEX IN SUBSTRATE TRANSFER, PILUS BIOGENESIS, AND RECIPIENT CELL CONTACT, Jay E. Gordon

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CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING, Natalie Sirisaengtaksin and Natalie Sirisaengtaksin

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Characterizing the source of neutrophil elastase and proteinase 3 cross-presentation in B-cell acute lymphoblastic leukemia, Selena Carmona

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CIRCULATING AUTOANTIBODIES IN HUMAN TRAUMATIC SPINAL CORD INJURY SUBJECTS AND THEIR RELATIONSHIP TO THE DEVELOPMENT OF NEUROPATHIC PAIN, Georgene Hergenroeder

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CLINICAL AND THERAPEUTIC SIGNIFICANCE OF OBESITY IN MELANOMA, Jennifer L. McQuade

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CLINICAL APPLICABILITY OF PROPOSED ALGORITHM FOR IDENTIFYING INDIVIDUALS AT RISK FOR HEREDITARY HEMATOLOGIC MALIGNANCIES, Maggie Clifford

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Computational Identification of Noncoding Driver Mutations Based on Impact on RNA Processing, Kevin Zhu

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Computer-Aided Detection of Pathologically Enlarged Lymph Nodes On Non-Contrast CT In Cervical Cancer Patients For Low-Resource Settings, Brian M. Anderson, Laurence E. Court, Ann Klopp, Stephen F. Kry, Jennifer Johnson, Erik Cressman, Arvind Rao, and Jinzhong Yang

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CONTRASTING EFFECTS OF AN MDM2 FUNCTIONAL POLYMORPHISM ON TUMOR PHENOTYPES, Guadalupe J. Ortiz IV

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Cyclin B1 mediates the effect of UCHL1 in promoting cell cycle progression in uterine papillary serous carcinoma, Suet Ying Kwan

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CYTOPLASMIC CYCLIN E MEDIATES RESISTANCE TO AROMATASE INHIBITORS IN BREAST CANCER, Iman Doostan

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Detecting and Evaluating Therapy Induced Changes in Radiomics Features Measured from Non-Small Cell Lung Cancer to Predict Patient Outcomes, Xenia J. Fave

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DEVELOPING NOVEL APPROACHES TO IMPROVE RESPONSE TO T CELL BASED CANCER IMMUNOTHERAPY, Rina M. Mbofung

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DYNAMIC ASSESSMENT OF NK CELL INTERACTIONS WITH PEDIATRIC TUMOR CELLS TO PREDICT RESPONSE TO IMMUNOTHERAPY, Arianexys Aquino Lopez

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EFFECT OF ENTINOSTAT ON NK CELL-MEDIATED CYTOTOXICITY AGAINST OS CELLS AND OS LUNG METASTSIS, Simin Kiany

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ENDOCYTIC TRAFFICKING OF THE AMYLOID PRECURSOR PROTEIN IN RAT CORTICAL NEURONS, sahily reyes

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Evaluating the impact of post-translational modifications by the secreted zinc metalloprotease, GelE, on the major autolysin of E. faecalis, AtlA, and a stress-induced protein, SalB, Emily K. Stinemetz

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EVALUATING THE THERAPEUTIC EFFICACY OF RESTORING WILD-TYPE P53 ACTIVITY IN P53-MUTANT TUMORS, Connie A. Larsson

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FRET-Based Investigations of the Structure-Function Relationships in the NMDA Receptor, Drew M. Dolino

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FUNCTIONAL ASYMMETRY OF THE IMMUNE CELL PLASMA MEMBRANE, Eric Malmberg

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Functional consequences of RNA exosome complex alteration by conformational changes and cofactor binding, Jaeil Han

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FURTHER ADVANCES FOR THE SEQUENTIAL MULTIPLE ASSIGNMENT RANDOMIZED TRIAL (SMART), TIANJIAO DAI

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Gcn5 Impacts FGF Signaling At Multiple Levels And Activates C-Myc Target Genes During Early Differentiation Of Embryoid Bodies, Li Wang

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Genesurance Counseling: Patient Perspectives, Chelsea Wagner

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GSK3B regulates epithelial-mesenchymal transition and cancer stem cell properties and is a novel drug target for triple-negative breast cancer, Geraldine Vidhya Raja

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HIGH-THROUGHPUT MAPPING OF THE BIOLOGICAL EFFECTS OF PARTICLE THERAPY, Lawrence Bronk

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HSP27 AND CHEMOTHERAPY-INDUCED AUTOPHAGY AS BIOMARKERS IN OSTEOSARCOMA, John Andrew Livingston

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HYPOXIA-INDUCED AMOEBOID CANCER CELL MIGRATION: PRINCIPLES, MOLECULAR MECHANISMS AND PLASTICITY, Veronika Boekhorst

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IDENTIFYING THE IMMUNE RELATED METABOLIC PROPERTIES OF PANCREATIC CANCER USING NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND DYNAMIC MAGNETIC RESONANCE SPECTROSCOPIC IMAGING WITH HYPERPOLARIZED PYRUVATE, Joseph Weygand

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Image Registration to Map Endoscopic Video to Computed Tomography for Head and Neck Radiotherapy Patients, William S. Ingram

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IMPACT OF KRAS/NRAS MUTATIONAL HETEROGENEITY ON CLINICAL OUTCOMES IN COLORECTAL CANCER, Jonathan M. Loree

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Improvements in four-dimensional and dual energy computed tomography, Rachael M. Martin

Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy Plans for Lung Cancer Patients with 4-Dimensional Robust Optimization, shuaiping ge

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IMPROVING NK CELL THERAPY FOR OSTEOSARCOMA, Jennifer Foltz

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INSIGHTS INTO THE THERAPEUTIC POTENTIAL OF SALT INDUCIBLE KINASE 1: A NOVEL MECHANISM OF METABOLIC CONTROL, Randi Fitzgibbon

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INTEGRATIVE ANALYSIS OF OMICS DATA IN ADULT GLIOMA AND OTHER TCGA CANCERS TO GUIDE PRECISION MEDICINE, Xin hu and xin hu

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INTEGRATIVE CANCER IMMUNOGENOMIC ANALYSIS OF SERIAL MELANOMA BIOPSIES REVEALS CORRELATES OF RESPONSE AND RESISTANCE TO SEQUENTIAL CTLA-4 AND PD-1 BLOCKADE TREATMENT, Whijae Roh

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Investigating the Neural Basis of Audiovisual Speech Perception with Intracranial Recordings in Humans, Muge O. Sertel

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INVESTIGATING THE ROLE OF PRMT1 AND ARGININE METHYLATION OF HSP70 IN HUMAN PANCREATIC CANCER, Liang Wang

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INVESTIGATION OF THE ROLES OF ASF1 AND CAF-1-MEDIATED CHROMATIN ASSEMBLY IN THE HUMAN DNA DAMAGE RESPONSE, Ting-Hsiang Huang

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INVOLVEMENT OF THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS (RAGE) IN PROGRESSION OF PANCREATIC CANCER, Nancy Azizian MS

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LBPI: A WEB INTERFACE FOR THE IDENTIFICATION OF ALLOSTERIC LIGAND BINDING SITES, Nabina Paudyal

LBPI: A WEB INTERFACE FOR THE IDENTIFICATION OF ALLOSTERIC LIGAND BINDING SITES, Nabina Paudyal

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MANAGING VARIANT DISCREPANCY IN HEREDITARY CANCER: CLINICAL PRACTICE, BARRIERS, AND DESIRED RESOURCES, Ellen Zirkelbach

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MATHEMATICAL MODELING REVEALS THAT G2/M CHECKPOINT OVERRIDE, Hui Ju Hsieh

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MATHEMATICAL MODELING REVEALS THAT G2/M CHECKPOINT OVERRIDE CREATES A THERAPEUTIC VULNERABILITY IN TSC2-NULL TUMORS, Hui Ju Hsieh

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MATHEMATICAL MODELING REVEALS THAT G2/M CHECKPOINT OVERRIDE CREATES A THERAPEUTIC VULNERABILITY IN TSC2-NULL TUMORS, Hui-Ju Hsieh

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MECHANISM OF CANDIDA ALBICANS BIOFILM AND VIRULENCE INHIBITION BY A BACTERIAL SECRETED FACTOR, Carrie Graham

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MECHANISMS UNDERLYING THE SENSITIVITY AND RESISTANCE OF GASTRIC CANCER CELLS TO MET INHIBITORS, Rebecca Schroeder

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Membrane Bound IL21 Promotes Natural Killer Cell Expansion Through mIR 124-3p Mediated Regulation, Anitha Somanchi

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Memory Potential, Molecular Characterization, and Translational Applications of the Novel ThEO/TcEO T Cell Phenotype, Todd Bartkowiak and Todd Bartkowiak

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Mitochondrial Fission After Traumatic Brain Injury, Tara Fischer

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Modeling Post Stroke Respiratory Dysfunction, Apneas and Cognitive Decline, Anthony Patrizz

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MODIFICATION OF APLYSIA FEEDING NETWORK BY L-DOPA AND DOPAMINE-DEPENDENT LEARNING, Curtis Neveu and Curtis L. Neveu

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MOLECULAR DETERMINANTS OF RESIDUAL DISEASE IN OVARIAN CANCER, Kshipra M. Gharpure

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MOLECULAR MECHANISMS OF INWARD AND OUTWARD BUDDING FROM MULTIVESICULAR ENDOSOMES, Monica Gireud Goss

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NON-CODING RNAS IDENTIFY THE INTRINSIC MOLECULAR SUBTYPES OF MUSCLE-INVASIVE BLADDER CANCER, Andrea E. Ochoa

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NOVEL BAYESIAN ADAPTIVE CLINICAL TRIAL DESIGNS IN EARLY PHASES, Haitao Pan

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On the Origin of Sensory Errors, Jonathan R. Flynn

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Optogenetic interrogation of primary visual cortex and its impact on neural coding and behavior, Ariana R. Andrei

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PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression, Shiping Jiao

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PEPTIDE VACCINE FORMULATION CONTROLS THE DURATION OF ANTIGEN PRESENTATION AND MAGNITUDE OF TUMOR‐SPECIFIC CD8+ T CELL RESPONSE, Hiep Khong

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Pharmacologic and Genetic Manipulations of Angiotensin Signaling in Thoracic Aortic Disease Models, Andrew M. Peters

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PHOPSPHORYLATION AND UBIQUITIN MODIFICATION AT DNA DAMAGE SITES IN RESPONSE TO DOUBLE-STRAND BREAKS, Atanu Paul

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Preclinical Development of Therapeutic Strategies Against Triple-Negative and Inflammatory Breast Cancer, Angie M. Torres-Adorno

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PROTEOMIC IDENTIFICATION OF HISTONE POST-TRANSLATIONAL MODIFICATIONS INDUCED BY DNA DOUBLE-STRAND BREAKS AND NOVEL PROTEINS INVOLVED IN THE DNA DAMAGE RESPONSE, Pingping Wang

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Quality of Life: Socio-Demographic and Genetic Determinants as well as Links with Cancer Outcomes, Jeanne Pierzynski

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Quantitative DWI as an Early Imaging Biomarker of the Response to Chemoradiation in Esophageal Cancer, Benjamin C. Musall

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ROLE AND REGULATION OF SPHINGOSINE 1-PHOSPHATE IN ERYTHROCYTE, Kaiqi Sun

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STATISTICAL METHODS FOR ASSESSING STRUCTURAL CHANGE IN HUMAN & MICROBIAL GENOMES, Xuan Zhu

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Statistical Methods for Two Problems in Cancer Research: Analysis of RNA-seq Data from Archival Samples and Characterization of Onset of Multiple Primary Cancers, Jialu Li

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Stromal Fibroblasts Restrain the Rate of Colon Cancer Progression and Metastasis by Suppressing Regulatory T Cells and Colon Cancer Stem Cells, Changsoo Kwak

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STRUCTURAL AND FUNCTIONAL EFFECT OF PHOSPHORYLATION ON AMPA RECEPTORS, Caitlin E. Nurik

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STUDY OF REGULATED CELL DEATH IN TWO SYSTEMS: PD-1 IN NATURAL KILLER CELLS AND RIP3 IN NEURONS, YU HUANG

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TARGETING APOPTOTIC PATHWAYS TO OVERCOME DRUG RESISTANCE IN ACUTE MYELOID LEUKEMIA, Rongqing Pan

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TARGETING AUTOPHAGY TO IMPROVE EFFICACY OF CDK4/6 INHIBITION IN BREAST CANCER, Smruthi Vijayaraghavan

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Targeting Epigenetic Regulators for the Treatment of Diffuse Large B-Cell Lymphoma, Aarthi Goverdhan

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The External Globus Pallidus: Bidirectional Control Over Anxiety-Related Behavior Mediated by CRFR1, Albert J. Hunt Jr

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The functions of SETD5 and miR-221 in embryonic stem cell differentiation, Tsai-Yu Chen

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The Hypoxic Adenosine Response Modulates Macrophage Differentiation and Contributes to Lung Disease, Kemly Mary Philip

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THE ROLE OF ADENOSINE SIGNALING IN MATURE ERYTHROCYTES AND ERYTHROID PROGENITORS, Hong Liu

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The Role of the DIRAS Family Members in Regulating Ras Function, Cancer Growth and Autophagy, Margie Nicole Sutton

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THE ROLE OF THE EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) IN LUNG CANCER PROGRESSION, David H. Peng

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The Utilization of Prenatal Microarray: A Survey of Current Genetic Counseling Practices and Barriers, Leslie N. Durham and Leslie Durham

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TUMOR-CELL DERIVED INHIBIN, BETA A IS ESSENTIAL FOR ADRENERGIC EFFECTS ON FIBROBLAST ACTIVATION, Archana Sidalaghatta Nagaraja

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Undergraduate Student Perceptions and Awareness of Genetic Counseling, Amanda Gerard

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UNDERSTANDING THE MECHANISM OF GENOMIC INSTABILITY DURING REPLICATIVE AGING IN BUDDING YEAST, Sangita Pal

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VISUALIZING THE DYNAMICS OF IMMUNE SURVEILLANCE IN BRAIN TUMORS BY INTRAVITAL MULTIPHOTON MICROSCOPY, Felix Nwajei

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VOLUMETRIC, MAGNETIC RESONANCE-VISIBLE, AND RADIATION-SENSITIVE DETECTORS FOR MAGNETIC RESONANCE IMAGE-GUIDED RADIATION THERAPY, Hannah J. Lee

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WISP1 IS AN OVEREXPRESSED DRIVER OF GLIOBLASTOMA, Pushan R. Dasgupta

Theses/Dissertations from 2016

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Accurate mutation annotation and functional prediction enhance the applicability of -omics data in precision medicine, Tenghui Chen

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AN AUTOMATED SYRINGE PUMP SYSTEM FOR IMPROVING THE REPRODUCIBILITY OF DYNAMIC HYPERPOLARIZED MRI PHANTOMS, Harlee G. Harrison

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A Phase I dose-escalation study of the BRAF inhibitor vemurafenib in combination with the MTOR inhibitor everolimus in subjects with advanced cancer, Javier Munoz

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Assessing the Potential Clinical Impact of Variable Biological Effectiveness in Proton Radiotherapy, Christopher R. Peeler Ph.D.

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Attitudes Towards Prenatal Genetics Among Southeast and East Asian Women: A Qualitative Pilot Study, GINGER J. TSAI

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BIAS AND VARIABILITY IN IMAGE-BASED VOLUMETRIC YTTRIUM-90 DOSIMETRY, Wendy Siman