Open-access, full-text copies of The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.
Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.
Older GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.
Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.
Theses/Dissertations from 2021
Genetic Pathway Analysis of Abnormal Facial Development in Nonsyndromic Cleft Lip and Palate, lorena maili
Genetics in the NICU: Nurses’ Perceived Knowledge and Desired Education, Kathleen Shields
Genetic Testing in Pregnancies with Ultrasound Anomalies: Exploration of Factors that Influence Uptake, Lukas D. Kruidenier
Hypoxia Acts as an Environmental Cue for the Human Tissue-Resident Memory T-cell Differentiation Program, Farah Hasan
Identification and characterization of de novo germline TP53 mutation carriers in families with Li-Fraumeni Syndrome, Carlos C. Vera Recio
Imaging Based Prediction of Pathology in Adult Diffuse Glioma with Applications to Therapy and Prognosis, Evan Gates
Impact of Intratumor Heterogeneity and the Tumor Microenvironment in Shaping Tumor Evolution and Response to Therapy, Akash Mitra
IMPROVING TREATMENT OF LOCAL LIVER ABLATION THERAPY WITH DEEP LEARNING AND BIOMECHANICAL MODELING, Brian Anderson, Kristy Brock, Laurence Court, Carlos Eduardo Cardenas, Erik Cressman, and Ankit Patel
Increased oxidative phosphorylation in an iPSC- derived model of Rothmund-Thomson syndrome associated osteosarcomagenesis, Brittany Jewell
INTRANASAL HPV PEPTIDE VACCINE FORMULATION INDUCES POTENT CYTOTOXIC CD8 T CELL IMMUNITY FOR THE TREATMENT OF GENITAL HPV TUMORS, Gloria Sierra
INVESTIGATING DIFFUSION TENSOR IMAGING CORRELATES OF COGNITIVE IMPAIRMENT IN IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS AND ALZHEIMER'S DISEASE, Omar Hasan and Omar Hasan
Investigating Mechanisms in Nociceptors Driving Ongoing Activity and Ongoing Pain, Elia Lopez
INVESTIGATING THERAPEUTIC STRATEGIES TO TARGET METABOLIC VULNERABILITIES OF NSCLC TUMORS WITH MUTANT KEAP1 GENE, Pranavi Koppula
Investigating the role of Abro1 in DNA damage-induced immune response, Ahmed Emam
Investigation of trophon® 2 for High Level Disinfection of Rigid Endorectal MRI Coils, Rebecca DiTusa
Isolated, Absent Cavum Septum Pellucidum: A Single Center’s Outcomes and Review of the Literature, Renee Bardini
LGR5 Regulation of STAT3 Signaling and Drug Resistance in Colorectal Cancer, Tressie Posey and Tressie Alexandra Posey
MANIPULATING ENHANCER RNA ACTIVITY TO STUDY THEIR ROLES IN GENE REGULATION AND CANCER, Zian Liao
MicroRNAs as a Therapeutic Target to Regulate Microglial Activation in Post Stroke Isolation in Aged Male Mice, Anik Banerjee
Mitochondrial Unfolded Protein Response Regulator ATF5 in Mitochondrial Targeted Therapies in AML, Ran Zhao
Mixture Model Approaches to Integrative Analysis of Multi-Omics Data and Spatially Correlated Genomic Data, Ziqiao Wang
Modulating Immunometabolism to Improve the Activity of CAR-NK Cells Targeting CD70 in Renal Cell Carcinoma, Hind Rafei
MODULATION OF THE RECEPTOR GATING MECHANISM AND ALLOSTERIC COMMUNICATION IN IONOTROPIC GLUTAMATE RECEPTORS, Nabina Paudyal and Nabina Paudyal
MOLECULAR DRIVERS OF BLADDER CANCER MOTILITY, Bryan Wehrenberg
Mutant KRAS Alters Extracellular Vesicle MicroRNA Sorting in Pancreatic Cystic Neoplasms, Rachel L. Dittmar
NPSD4: A NEW PLAYER IN SUMO-DEPENDENT DNA REPAIR, Erin Atkinson
Quantitative Magnetic Resonance Imaging for the Early Prediction of Treatment Response in Triple Negative Breast Cancer, Benjamin C. Musall
Rare variant association studies in Crohn’s Disease and Colorectal Cancer: methods and applications, Jiun-Sheng Chen
REGULATION OF LUNG MESENCHYMAL CELLS BY EPITHELIAL WNT LIGANDS, Odemaris Narvaez del Pilar
ROLE OF METHYLTRANSFERASE LIKE-3 (METTL3) IN PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) PROGRESSION, Bhargavi Brahmendra Barathi
Spectrum and Incidence of Primary and Therapy-Related Hematologic Malignancies in Individuals with BRCA1 and BRCA2 Pathogenic Variants, Rosemary Rogers and Rosemary Rogers
STAT3 INHIBITS TYPE I INTERFERON SIGNALING IN TYPE I CONVENTIONAL DENDRITIC CELLS, Taylor Chrisikos
SYNTHETIC ESSENTIALITY OF TDO2 IN APC-MUTATED COLORECTAL CANCER, Rumi Lee
Targeting Plasma Membrane Phosphatidylserine Content to Inhibit Oncogenic KRAS Function, Walaa E. Kattan
The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin, Amelie Simone Cordelia Albrecht
The Functional Contribution Of Adaptive Immunity In The Biology Of Pancreatic Cancer And Therapeutic Targeting Of Oncogenic Kras, Krishnan Mahadevan
The impact of synchrony on neuronal coding and behavior, Natasha Kharas
The Importance of DNA Repair Capacity to (and a Model to Predict) Cell Radiosensitivity to Ions, David B. Flint and David B. Flint
The role of IFITM3 in the immune response of BRCA-deficient high grade serous ovarian carcinoma, Han Cun
The Role of PAG1 in the Activated B-Cell Subtype of Diffuse Large B-Cell Lymphoma, Jared Henderson
The Src- and Abl- Dependent Regulation of Net1A in Breast Cancer, Ashabari Sprenger
TRIM24 promotes mammary tumor development by upregulating metabolic reducing power, Shucheng Miao
Understanding the Pathogenesis of Renal Medullary Carcinoma, Melinda Soeung
UNDERSTANDING THE ROLE OF ARGLU1 IN INTERFERON SIGNALING ACTIVATION IN BREAST CANCER, Phuoc Nguyen
Unraveling Host-Gut Microbiota Dialogue and Its Impact on Response to Immune Checkpoint Blockade, Alexandria Cogdill
Unveiling global roles of G-quadruplexes and G4-22 in human genetics, Ruth Barros De Paula
Vascular Disease Pathogenesis in Smooth Muscle Dysfunction Syndrome and Majewski Osteodysplastic Primordial Dwarfism Type II, Jamie Wright
Virulence and biofilm formation in Candida albicans are inhibited by short peptide subunits of EntV, Shane Cristy
Theses/Dissertations from 2020
A CONTEXT-FORWARD IN VIVO FUNCTIONAL GENOMICS PLATFORM FOR TARGET DISCOVERY AND ESTABLISHING VULNERABILITY CONTEXT IN PANCREATIC CANCER, Johnathon Rose and Johnathon Lynn Rose
ACTIVE MAGNETIC RADIATION SHIELDING FOR LONG-DURATION HUMAN SPACEFLIGHT, Kristine Ferrone
Aging Lowers PEX5 Levels in Cortical Neurons in Male and Female Mouse Brains, Ndidi-Ese Uzor
ALTERNATIVE CARBON UTILIZATION AS A VIRULENCE DETERMINANT FOR CANDIDA ALBICANS, Robert Williams
An Exploration of Neuroanatomical Signatures of Pediatric Bipolar Disorder Using Structural Neuroimaging, Jonika Tannous
A Pharmacological Strategy Against African Sleeping Sickness, Wahaj Zuberi
Artificial intron technology to generate conditional knock-out mice, Amber N. Thomas-Gordon
A SCREEN FOR PEPTIDES TARGETING CHEMORESISTANT METASTATIC TRIPLE-NEGATIVE BREAST CANCER, Shraddha Subramanian
Assessing Patient Attitudes toward Genetic Testing for Hereditary Hematologic Malignancy, Addison Johnson
ASTROCYTES RESCUE NEURONAL HEALTH AFTER CISPLATIN TREATMENT THROUGH MITOCHONDRIAL TRANSFER., Krystal English and Krystal English
BAYESIAN ADAPTIVE DESIGNS AND VERSATILE SOFTWARE PLATFORM FOR EARLY PHASE CLINICAL TRIALS, Yanhong Zhou
BRINGING TIL THERAPY BEYOND MELANOMA: ADVANCING THE TREATMENT OF ADVANCED PANCREATIC AND OVARIAN CANCERS, Donald Sakellariou-Thompson
BST2 ISOFORMS: DISTRIBUTION AND POTENTIAL USE IN CANCER THERAPEUTICS, Ahmed Muhsin
Calcium Dyshomeostasis in Neurodegeneration, Nicholas Emanuel Karagas
CELLULAR AND CIRCUIT PROPERTIES OF SLOW OSCILLATIONS IN THE THALAMIC RETICULAR NUCLEUS, John O'Malley
Characterization of Treatment Planning System Photon Beam Modeling Errors in IROC Houston Phantom Irradiations, Mallory Glenn
COMBINED INHIBITION OF DDR1 AND CDK4/6 INDUCES SYNERGISTIC EFFECTS IN ER-POSITIVE, HER2-NEGATIVE BREAST CANCER WITH PIK3CA/AKT1 MUTATIONS, maryam shariati and maryam shariati
DECODING THE EVOLUTIONARY RESPONSE TO PROSTATE CANCER THERAPY USING PLASMA GENOME SEQUENCING, Naveen Ramesh
DEVELOPMENT OF A CT METAL ARTIFACT MANAGEMENT ALGORITHM FOR PROTON THERAPY PLANNING (AMPP) FOR HEAD AND NECK CANCER PATIENTS, Daniela Branco
DEVELOPMENT OF COMPUTATIONAL TOOLS TO TARGET MICRORNA, Luo Song
Development of fully balanced SSFP and computer vision applications for MRI-assisted radiosurgery (MARS), Jeremiah Sanders
Directed Evolution of Macrocyclic Peptides for Inhibition of Autophagy, Joshua Gray
Disruption of DNA Polymerase Zeta Promotes an Innate Immune Response, Sara Martin
Effect of sympathetic nervous system mediators on the tumor microenvironment via small extracellular vesicles in ovarian cancer, Sujanitha Umamaheswaran and Sujanitha Umamaheswaran
Elevated cochlear adenosine causes hearing loss via ADORA2B signaling, Jeanne Manalo
ELUCIDATING THE ROLES OF IL-15 IN THE TUMOR MICROENVIRONMENT, Rosa Maria Santana Carrero
Factors that Impact Uptake of Carrier Screening by Male Reproductive Partners of Female Prenatal Patients, Wendi Betting
Fibroblast Heterogeneity in Pancreatic Cancer Immunity, Josephine Darpolor
Frequency of copy number variants involving the sex chromosomes in a clinical setting, Autumn Vara
Functional heterogeneity and metabolic adaptation of fibroblasts in cancer, Lisa Becker
GENETIC AND CLINICAL DETERMINANTS OF RACIAL/ETHNIC DIFFERENCES IN MULTIPLE MYELOMA SUSCEPTIBILITY AND OUTCOMES FOCUSING ON HISPANICS, Alem Belachew
Genetic Counselors' Approaches to Direct-to-Consumer Genetic Testing for Hereditary Breast Cancer, Sarah Burke
Genetic Counselors' Experiences with and Approaches to Discordant Genotypic and Phenotypic Sex Detected via Non-Invasive Prenatal Testing, Emily Stiglich
GREAT EXPECTATIONS: PHOSPH(ON)ATE PRODRUGS IN DRUG DESIGN—OPPORTUNITIES AND LIMITATIONS, Victoria Yan
Heterogeneous Nuclear Ribonucleoprotein K (hnRNP K) Overexpression and its Interaction with RUNX1 RNA in Acute Myeloid Leukemia, Marisa Aitken
Histological and functional characterization of cervical spinal cord injury after graded contusion, Chrystine Gallegos
HYPERPOLARIZED CARBON-13 MAGNETIC RESONANCE MEASUREMENTS OF TISSUE PERFUSION AND METABOLISM, Keith Michel
Hypothalamic circuits mediating consumption and anxiety, Ryan Cassidy
IDENTIFICATION OF TRIM24 DOMAIN ESSENTIALITY IN PRIMARY TRIM24COE CARCINOSARCOMA CELL LINES, Cem Dede
IMPACT OF EPA AND DHA SUPPLEMENTATION AND 15-LOX-1 EXPRESSION ON COLITIS AND COLITIS-ASSOCIATED COLORECTAL CANCER, Jonathan Jaoude
Implementation of genetic carrier screening in the OB population: healthcare cost impact and recommendation adherence, Aranza Gonzalez Cendejas
INDUCIBLE EPITHELIAL RESISTANCE AGAINST ACUTE VIRAL PNEUMONIA AND CHRONIC ASTHMA, Shradha Wali
INDUCIBLE EPITHELIAL RESISTANCE AGAINST ACUTE VIRAL PNEUMONIA AND CHRONIC ASTHMA, Shradha Wali
INFLUENCE OF GENETIC COUNSELOR PERSONAL OR FAMILY MEDICAL HISTORY ON GENETIC COUNSELING SPECIALIZATION AND PRACTICE, Kaitlyn K. Amos MS
Investigating Medical Examiners' Practices: Genetic Evaluation for Fatal Acute Aortic Dissection, Bradley Power
INVESTIGATING THE METABOLIC PROGRESSION OF GLIOBLASTOMA WITH HYPERPOLARIZED MAGNETIC RESONANCE, Travis Salzillo