Open Access full-text copies of the UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Older UT GSBS dissertations (approximately 1979-1999) are available in print-format only and are available in the HAM-TMC Library. They're listed in the Library Catalog under the subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences."

Some older full-text dissertations are also available via ProQuest but access to this database is restricted to the TMC community.

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Theses/Dissertations from 2012

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Characterization of a Novel Role for the Tousled- like Kinase in Kinetochore Assembly and Function in Caenorhabditis elegans, Jessica M. De Orbeta

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Novel Use of Dual Anti-Inflammatory Therapy to Overcome Drug Resistance and Improve Functional Recovery Following Spinal Cord Injury, Jennifer Dulin

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ANTI-TUMOR EFFECTS OF THE NOTCH PATHWAY IN GASTROINTESTINAL STROMAL TUMORS, Amaury G. Dumont

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LMW-E MEDIATES MAMMARY TUMORIGENESIS BY DEREGULATING ACINAR MORPHOGENESIS & GENERATING CANCER STEM CELLS, MyLinh T. Duong

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Syntaxin 6- and microtubule- mediated intracellular trafficking contributes to Golgi and nuclear translocation of EGFR, Yi Du

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ALLERGEN SENSITIZATION AND IMMUNOMODULATION BY SYNTHETIC LIGANDS, PUL-042, IN AN ALLERGEN-INDUCED ASTHMA MURINE MODEL, Maryann A. Edwards

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Cellular Trafficking of Single and Multistage Vectors, Silvia Ferrati

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IDENTIFICATION AND ANALYSIS OF A NOVEL ROLE FOR THE TOUSLED-LIKE KINASE IN REGULATING MITOTIC SPINDLE DYNAMICS, Jason R. Ford

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ACCURACY OF THE BRCAPRO RISK ASSESSMENT MODEL IN MALES PRESENTING TO MD ANDERSON FOR BRCA TESTING, Carolyn Garby; Banu Arun M.D; Michelle Jackson M.S., CGC; Jennifer Litton M.D; Syed Hashmi M.D., Ph.D; Sharon Giordano M.D, MPH; and Claire Singletary M.S, CGC

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REGULATION OF ALTERNATIVE CARBON METABOLISM IN CANDIDA ALBICANS, Arely Y. Gonzalez

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ROLE OF SOX9 IN UTERINE GLAND DEVELOPMENT AND DISEASE INITIATION, Gabriel Gonzalez

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INDUCED-PLURIPOTENT STEM-DERIVED NEURONAL PROGENITOR CELLS AS A NOVEL TREATMENT FOR NEURODEGENERATIVE DISEASES, Dennisse A. Gonzalez-Romero

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Deciphering the C-Type Lectin Receptor Signaling Pathway in Macrophages in Response to Candida albicans, Sara Gorjestani

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MUTATIONS IN STAT3 ASSOCIATED WITH HUMAN HYPER IgE SYNDROME ENHANCE NFκB AND MAPK-MEDIATED GENE EXPRESSION, Nathaniel Greeley

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Increased geranylgeranylated K-Ras contributes to antineoplastic effects of farnesyltransferase inhibitors., Mandy A. Hall

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Functional Characterization of AtxA, the Bacillus anthracis Virulence Regulator, Troy G. Hammerstrom

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POPULATION CODING IN LAMINAR CORTICAL CIRCUITS, Bryan J. Hansen

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Exploring the Impact of Decreased AMPK Pathway Activity on Brain Injury Outcome, Julia L. Hill

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Elucidating the IGFBP2 signaling pathway in glioma development and progression, Kristen M. Holmes

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Homology Cloning, Heterologous Expression and Characterization of a New Channelrhodopsin, Sing-Yi Hou

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Improved Techniques for Acquisition and Analysis of Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Detecting Vascular Permeability in the Central Nervous System, Cheukkai Hui

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Simultaneous induction of NKG2D and NKG2D ligand for promoting immune surveillance by IL-12 plus doxorubicin treatment, Jiemiao Hu

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DIRECT EFFECTS OF METFORMIN ON PI3K AND RAS SIGNALING IN ENDOMETRIAL CANCER, David A. Iglesias M.D.

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Differential Activity of the KRAS Oncogene by Method of Activation: Implications for Signaling and Therapeutic Intervention, Nathan Ihle

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TET1: A UNIQUE DNA DEMETHYLASE FOR MAINTENANCE OF DNA METHYLATION PATTERN, CHUNLEI JIN

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NOVEL PHANTOMS AND POST-PROCESSING FOR DIFFUSION SPECTRUM IMAGING, Vaibhav Juneja

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The Role of the Arched Helicases in Exosome-Mediated Function, A. Alejandra Klauer

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Post-transcriptional Regulation of Mammalian Gene Expression in Non-coding Region of Target RNA, Jing Lin

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MicroRNA Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development, Can Liu

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IKKalpha mediated NOTCH1 Activation Promotes Tumorigenesis via FOXA2 Suppression, Mo Liu

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GENETIC ANALYSIS OF THE HIPPO PATHWAY IN MOUSE LIVER, Li Lu

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Cellular Uptake of Neutrohpil Elastase Links Inflammation to Adaptive Immunity, Elizabeth A. Mittendorf

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Regulation of Net1A subcellular localization by the small GTPase Rac1, Christopher A. Morris

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Targeting TRAF6 for Cancer Therapeutical Development, John K. Morrow

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Long Term Follow-up of Morbidity and Quality of Life Associated with Isolated Gastroschisis, Roya M. Mostafavi

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Knowledge, Attitudes, and Utilization of BRCA Testing Among Obstetricians and Gynecologists, Salma Nassef

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COMPREHENSIVE CALCULATION-BASED IMRT QA USING R&V DATA, TREATMENT RECORDS, AND A SECOND TREATMENT PLANNING SYSTEM, Jared D. Ohrt, Peter Balter, Michael Gillin, Court Laurence, Issac Rosen, and Valen Johnson

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DEVELOPMENT OF A BEAM-SPECIFIC PLANNING TARGET VOLUME AND A ROBUST PLAN ANALYSIS TOOL FOR PROTON THERAPY, Peter Park

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Evaluation of Knowledge Regarding Diagnostic Strategies for Genetic Diseases in Select Residents, Samantha Penney

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A STUDY ON THE FUNCTION OF 14-3-3SIGMA IN REGULATING CANCER ENERGY METABOLISM, Liem M. Phan and Liem M. Phan

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EVIDENCE OF HUMAN ENDOGENOUS RETROVIRUS K INVOLVEMENT IN HUMAN CANCER, Joshua B. Plummer

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A Pre-Clinical Assessment of Minocycline for Treatment of Chronic Neuropathic Pain after Spinal Cord Injury, Alissa R. Poteete

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Genetic Predictors of Clinical Outcomes in Non-Small Cell Lung Cancer Patients, Xia Pu

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ROLE OF STAT3 IN KERATINOCYTE STEM CELLS DURING SKIN TUMORIGENESIS, Dharanija Rao

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CHEMOSENSITIZATION OF HEPATOCELLULAR CARCINOMA TO GEMCITABINE BY NON-INVASIVE RADIOFREQUENCY FIELD-INDUCED HYPERTHERMIA, Mustafa Raoof

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CHARACTERIZATION AND TREATMENT OF A NOVEL MOUSE MODEL OF TSC-ASSOCIATED AUTISM, Rachel Michelle Reith

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EVALUATION OF THE EFFECTIVENESS OF ANISOTROPIC ANALYTICAL ALGORITHM IN FLATTENED AND FLATTENING-FILTER-FREE BEAMS FOR HIGH ENERGY LUNG DOSE DELIVERY USING THE RADIOLOGICAL PHYSICS CENTER LUNG PHANTOM, Roman Repchak and David Scott Followill

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BIM MEDIATES IMATINIB-INDUCED APOPTOSIS OF GASTROINTESTINAL STROMAL TUMORS: TRANSLATIONAL IMPLICATIONS, David Reynoso

Potential REST Targets in Neural Stem Cells and Glioblastoma-Derived Stem Cells, Frederick Scott Robinson

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Attitudes About Predictive MEN1 Genetic Testing in Minors, Katherine Rock

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HUMAN ENDOGENOUS RETROVIRUS K AS A NOVEL TUMOR-ASSOCIATED ANTIGEN FOR DEVELOPMENT OF AN OVARIAN CANCER VACCINE, kiera rycaj

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TAZ AS A REGULATOR OF MESENCHYMAL TRANSFORMATION AND CLINICAL AGGRESSIVENESS IN GLIOMAS, Katrina Salazar

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Understanding the Influence of Photon Energy on 6MV Non Reference Dosimetry and CT Dosimetry using TLD and OSLD, Sarah B. Scarboro

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Metabolic Regulation of mTOR Activation and Endoplasmic Reticulum Stress in the Heart, Shiraj Sen

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REGULATION OF FOXC2 EXPRESSION AND FUNCTION DURING EPITHELIAL-MESENCHYMAL TRANSITION BY GSK-3β, Maryam Shariati

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IMMUNOLOGICAL MECHANISMS OF EXTRACORPOREAL PHOTOPHERESIS IN CUTANEOUS T CELL LYMPHOMA AND GRAFT VERSUS HOST DISEASE, Lisa Shiue

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Pathologic Markers of Prognosis in Ampullary Carcinoma, Rachna T. Shroff

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CHARACTERIZATION OF THE COUNT RATE PERFORMANCE AND EVALUATION OF THE EFFECTS OF HIGH COUNT RATES ON MODERN GAMMA CAMERAS, Michael S. Silosky

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Predictors of Contralateral Breast Cancer in BRCA Negative Women, Ann E. Simmons

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TRANSCRIPTIONAL AND POST-TRANSLATIONAL MECHANISMS CONTRIBUTE TO MAINTENANCE OF REST IN NEURAL TUMORS, Akanksha Singh

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IDENTIFICATION AND CHARACTERIZATION OF DISTINCT POPULATIONS OF CLONOGENIC BONE MARROW STROMAL CELLS CAPABLE OF TRANSFERRING THE HEMATOPOIETIC MICROENVIRONMENT IN VIVO AND SUPPORTING LT-HSCs IN VITRO, Colby Suire

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THE NEW ROLE OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9: A CONNECTION OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9, APOLIPOPROTEIN B, and AUTOPHAGY, Hua Sun

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Understanding the roles of Non-homologous end joining and p53 after DNA damage, Omid Tavana

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Systems Biology Approaches to Probe Gene Regulation in Bacteria, Diogo F. Troggian Veiga

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Verification of the clinical implementation of the respiratory gated beam delivery technique with synchrotron-based proton irradiation, Yoshikazu Tsunashima

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BIOCHEMICAL CHARACTERIZATION OF BINDING PARTNERS OF TWO HSP70 CO-CHAPERONES IN SACCHAROMYCES CEREVISIAE, Jacob Verghese

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Evaluation of Polymer Gel Dosimeters for Measurements of Dose and LET in Proton Beams, Kevin M. Vredevoogd

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LOW REACTIVE OXYGEN SPECIES AND HIGH GLYCOLYSIS IN GLIOBLASTOMA STEM CELLS:MECHANISMS AND THERAPEUTIC IMPLICATIONS, Feng Wang

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GENETIC INTERACTIONS OF FACTORS THAT REGULATE ALTERNATIVE RNA SPLICING IN THE MALE GERM LINE OF DROSOPHILA, Shanzhi Wang

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Regulation of the heat shock response by thiol-reactive compounds in the yeast Saccharomyces cerevisiae, Yanyu Wang

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FANCM AND FAAP24 MAINTAIN GENOMIC STABILITY THROUGH COOPERATIVE AND UNIQUE FUNCTIONS, Yucai Wang

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IDENTIFYING GENETIC VARIANTS AND CHARACTERIZING THEIR ROLE IN CLUBFOOT, Katelyn S. Weymouth

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14-3-3 ZETA OVEREXPRESSION SERVES AS A NOVEL MOLECULAR SWITCH TURNING TGF-BETA FROM TUMOR SUPPRESSOR TO TUMOR PROMOTER, Jia Xu

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ADHERENS JUNCTIONS AND THE ACTOMYOSIN NETWORK REGULATE ORGAN GROWTH BY MODULATING HIPPO PATHWAY ACTIVITY IN DROSOPHILA, Chih-Chao Yang

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EXPRESSION AND IMMUNOLOGICAL CHARACTERIZATION OF HERV-K TRANSMEMBRANE ENVELOPE PROTEIN IN HUMAN BREAST CANCER, Bingnan Yin

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TRIM24-REGULATED ESTROGEN RESPONSE IS DEPENDENT ON SPECIFIC HISTONE MODIFICATIONS IN BREAST CANCER CELLS, Teresa T. Yiu

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BIOLOGICAL MECHANISMS AND CLINICAL IMPLICATIONS OF BCR-ABL-INDUCED MITOCHONDRIAL OXIDATIVE STRESS AND CELL SURVIVAL IN CHRONIC MYELOID LEUKEMIA, Hui Zhang

Theses/Dissertations from 2011

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ATM Signaling to TSC2: Mechanisms and Implications for Cancer Therapy, Angela Alexander

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UNDERSTANDING NANOG'S ROLE IN CANCER BIOLOGY, Mark D. Badeaux

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Expression and Regulation of Human Cytochrome P450 4F Isoforms in Tissue Samples and Under TNF-Alpha Challenges, Jordan C. Bell

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MODIFICATION AND IMPLEMENTATION OF THE RPC HETEROGENEOUS THORAX PHANTOM FOR VERIFICATION OF PROTON THERAPY TREATMENT PROCEDURES, Anthony Blatnica

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BMP-SIGNALING REGULATES A COMMON TRANSCRIPTIONAL PROGRAM TO CONTROL FACIAL FORM AND SKELETAL MORPHOGENESIS, Margarita Bonilla-Claudio

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PURINERGIC SIGNALING REGULATES FILOPODIA-INDUCED ZIPPERING, Jessica Lynn Bowser

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Glycogen Synthase Kinase 3 is Required for Optimal AKT Activation, Debora S. Bruno

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Enforced expression of Tbx1 in fetal thymic epithelial cells antagonizes thymus organogenesis, Kim T. Cardenas

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Evaluation of deformable image registration for improved 4D CT-derived ventilation for image guided radiotherapy, Richard Castillo

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THE MECHANISM OF TUMORIGENESIS IN THE IMMORTALIZED HUMAN PANCREATIC CELL LINES: CELL CULTURE MODELS OF HUMAN PANCREATIC CANCER, Zhe Chang

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ROLE OF PROSTAGLANDIN E2 IN THE REGULATION OF PANCREATIC STELLATE CELLS HYPER ACTIVITY ASSOCIATED WITH PANCREATIC CANCER, Chantale Charo

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CELL POLARITY REGULATES ORGAN GROWTH THROUGH THE HIPPO PATHWAY, Chiao-Lin Chen

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Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin- Cytosine Deaminase-Uracil PhosphoribosylTransferase, Chun-Te Chen

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THE ROLE OF E2F1 IN THE RESPONSE TO DNA DOUBLE STRAND BREAKS, Jie Chen

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ROLE OF THE GCN5 HISTONE ACETYLTRANSFERASE IN SPINOCEREBELLAR ATAXIA TYPE 7 AND IN IMMATURE NEURONS, Yi Chun Chen

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Gene Discovery in Nonsyndromic Cleft Lip with or without Cleft Palate, Brett T. Chiquet

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Altered Responses to Endoplasmic Reticulum Stress in Pancreatic Cancer, Jennifer H. Choe

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COP 9 SIGNALOSOME SUBUNIT 6 STABILIZES COP1, A NOVEL E3 UBIQUITIN LIGASE FOR 14-3-3σ, Hyun Ho Choi

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ΔNp63 REGULATES A COMPLEX NETWORK OF TARGET GENES IN LIMB AND EPIDERMAL DEVELOPMENT, Min Soon Cho

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BRAIN ACTIVATION AND CONNECTIVITY IN NON-DISABLED MULTIPLE SCLEROSIS PATIENTS, Rene A. Colorado

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Development of a Bayesian Joint Logistic Model to Better Study the Association between Haplotypes and Disease, Anthony M. D'Amelio Jr

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Uptake And Metabolism Of 5’-AMP In The Erythrocyte Play Key Roles In The 5’-AMP Induced Model Of Deep Hypometabolism, Isadora Daniels

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CLINICAL TRIAL ENROLLMENT IN A MULTIDISCIPLINARY PROSTATE CANCER, Delora A. Domain