The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2023
A Cross-Species Proteomic Map Reveals Neoteny of Human Synapse Development, Li Wang, Kaifang Pang, Li Zhou, et al.
Atoh1 Drives the Heterogeneity of the Pontine Nuclei Neurons and Promotes Their Differentiation, Sih-Rong Wu, Jessica C Butts, Matthew S Caudill, et al.
The Atoh1-Cre Knock-In Allele Ectopically Labels a Subpopulation of Amacrine Cells and Bipolar Cells in Mouse Retina, Sih-Rong Wu and Huda Y Zoghbi
Tau Polarizes an Aging Transcriptional Signature to Excitatory Neurons and Glia, Timothy Wu, Jennifer M Deger, Hui Ye, et al.
Lateral Septum as a Melanocortin Downstream Site in Obesity Development, Yuanzhong Xu, Zhiying Jiang, Hongli Li, et al.
Lateral Septum as a Melanocortin Downstream Site in Obesity Development, Yuanzhong Xu, Zhiying Jiang, Hongli Li, et al.
Genetics and Pathogenesis of Parkinson's Syndrome, Hui Ye, Laurie A Robak, Meigen Yu, et al.
In Vivo Functional Characterization of Egfr Variants Identifies Novel Drivers of Glioblastoma, Kwanha Yu, Kathleen Kong, Brittney Lozzi, et al.
Functional Screening of Lysosomal Storage Disorder Genes Identifies Modifiers of Alpha-Synuclein Neurotoxicity, Meigen Yu, Hui Ye, Ruth B De-Paula, et al.
Implication of Chromosomal Microarray Analysis Prior to In-Utero Repair of Fetal Open Neural Tube Defect, R Zemet, E Krispin, R M Johnson, et al.
Targeting GBM With an Oncolytic Picornavirus Svv-001 Alone and in Combination With Fractionated Radiation in a Novel Panel of Orthotopic PDX Models, Huiyuan Zhang, Yuchen Du, Lin Qi, et al.
Reprogramming Tumour-Associated Macrophages To Outcompete Cancer Cells, Xian Zhang, Shun Li, Isha Malik, et al.
A Novel Pathogenic Mutation of MeCP2 Impairs Chromatin Association Independent of Protein Levels, Jian Zhou, Claudia Cattoglio, Yingyao Shao, et al.
Submissions from 2022
The TFEB-TGIF1 Axis Regulates EMT in Mouse Epicardial Cells, Elena Astanina, Gabriella Doronzo, Davide Corà, et al.
A Role for Insulin-Like Growth Factor 1 in the Generation of Epileptic Spasms in a Murine Model, Carlos J Ballester-Rosado, John T Le, Trang T Lam, et al.
The microRNA Processor DROSHA Is a Candidate Gene for a Severe Progressive Neurological Disorder, Scott Barish, Mumine Senturk, Kelly Schoch, et al.
Multiple Approaches Converge on Three Biological Subtypes of Meningioma and Extract New Insights From Published Studies, James C Bayley, Caroline C Hadley, Arif O Harmanci, et al.
A Sparse Representation Strategy To Eliminate Pseudo-HFO Events From Intracranial EEG for Seizure Onset Zone Localization, Behrang Fazli Besheli, Zhiyi Sha, Jay R Gavvala, et al.
Two Neuronal Peptides Encoded From a Single Transcript Regulate Mitochondrial Complex III in Drosophila, Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, et al.
De Novo Variants in EMC1 Lead to Neurodevelopmental Delay and Cerebellar Degeneration and Affect Glial Function in Drosophila, Hyung-Lok Chung, Patrick Rump, Di Lu, et al.
Development of Myelinating Glia: An Overview, Carlo D Cristobal and Hyun Kyoung Lee
Daam2 Regulates Myelin Structure and the Oligodendrocyte Actin Cytoskeleton through Rac1 and Gelsolin, Carlo D Cristobal, Chih-Yen Wang, Zhongyuan Zuo, et al.
BERENICE Final Analysis: Cardiac Safety Study of Neoadjuvant Pertuzumab, Trastuzumab, and Chemotherapy Followed by Adjuvant Pertuzumab and Trastuzumab in HER2-Positive Early Breast Cancer, Chau Dang, Michael S Ewer, Suzette Delaloge, et al.
Gene-Based Therapeutics for Rare Genetic Neurodevelopmental Psychiatric Disorders, Beverly L Davidson, Guangping Gao, Elizabeth Berry-Kravis, et al.
Regulation of Drosophila Oviduct Muscle Contractility by Octopamine, Sonali A Deshpande, Ethan W Rohrbach, James D Asuncion, et al.