The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2023
Single-Cell Multi-Omics Integration for Unpaired Data by a Siamese Network with Graph-Based Contrastive Loss, Chaozhong Liu, Linhua Wang, and Zhandong Liu
Hemizygous Variants in Protein Phosphatase 1 Regulatory Subunit 3F (PPP1R3F) Are Associated With a Neurodevelopmental Disorder Characterized by Developmental Delay, Intellectual Disability and Autistic Features, Zhigang Liu, Baozhong Xin, Iris N Smith, et al.
Methyl-Branched Liposomes as a Depot for Sustained Drug Delivery, Yang Li, Rachelle Shao, Claire A Ostertag-Hill, et al.
Aging Fly Cell Atlas Identifies Exhaustive Aging Features at Cellular Resolution, Tzu-Chiao Lu, Maria Brbić, Ye-Jin Park, et al.
Co-Transmitting Interneurons in the Mouse Olfactory Bulb Regulate Olfactory Detection and Discrimination, Ariel M Lyons-Warren, Evelyne K Tantry, Elizabeth H Moss, et al.
Cell-based Noninvasive Prenatal Testing (cbNIPT)-A Review on the Current Developments and Future Prospects, Mohamad Ali Maktabi, Liesbeth Vossaert, and Ignatia B Van den Veyver
The Fly Homolog of SUPT16H, a Gene Associated With Neurodevelopmental Disorders, Is Required in a Cell-Autonomous Fashion for Cell Survival, Mengqi Ma, Xi Zhang, Yiming Zheng, et al.
Prevalence of Pathogenic Germline Variants in Adult-Type Diffuse Glioma, Malcolm F McDonald, Lyndsey L Prather, Cassandra R Helfer, et al.
Cellular Composition and Circuit Organization of the Locus Coeruleus of Adult Mice, Andrew McKinney, Ming Hu, Amber Hoskins, et al.
Respiratory Quinone Switches from Menaquinone to Polyketide Quinone during the Development Cycle in Streptomyces sp. Strain MNU77, Kritee Mehdiratta, Sonam Nain, Meenakshi Sharma, et al.
Effects of Protein-Coding Variants on Blood Metabolite Measurements and Clinical Biomarkers in the UK Biobank, Abhishek Nag, Ryan S Dhindsa, Lawrence Middleton, et al.
TFEB-Mediated Lysosomal Exocytosis Alleviates High-Fat Diet-Induced Lipotoxicity in the Kidney, Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, et al.
Social Behavioral Impairments in SYNGAP1-Related Intellectual Disability, Hajer Naveed, Maria McCormack, and J Lloyd Holder
Rare De Novo Gain-of-Function Missense Variants in DOT1L Are Associated With Developmental Delay and Congenital Anomalies, Zelha Nil, Ashish R Deshwar, Yan Huang, et al.
Allelic Strengths of Encephalopathy-Associated UBA5 Variants Correlate Between In Vivo and In Vitro Assays, Xueyang Pan, Albert N Alvarez, Mengqi Ma, et al.
Sphingolipids in Neurodegenerative Diseases, Xueyang Pan, Debdeep Dutta, Shenzhao Lu, et al.
TFEB and TFE3 Control Glucose Homeostasis by Regulating Insulin Gene Expression, Adrien Pasquier, Nunzia Pastore, Luca D'Orsi, et al.
Rare EIF4A2 Variants Are Associated With a Neurodevelopmental Disorder Characterized by Intellectual Disability, Hypotonia, and Epilepsy, Maimuna S Paul, Anna R Duncan, Casie A Genetti, et al.
Antagonistic Effect of Cyclin-Dependent Kinases and a Calcium-Dependent Phosphatase on Polyglutamine-Expanded Androgen Receptor Toxic Gain of Function, Diana Piol, Laura Tosatto, Emanuela Zuccaro, et al.
Dynamic Mapping of Proteome Trafficking Within and Between Living Cells by TransitID, Wei Qin, Joleen S Cheah, Charles Xu, et al.
Autolysosomal Exocytosis of Lipids Protect Neurons From Ferroptosis, Isha Ralhan, Jinlan Chang, Matthew J Moulton, et al.
Cavernous Sinus Hemangioma: Histopathological Spectrum of 8 Cases, Joshua M Rasband, Rasha Alfattal, Akash J Patel, et al.
The Voltage-Gated Sodium Channel in Drosophila, Para, Localizes to Dendrites As Well As Axons in Mechanosensitive Chordotonal Neurons, Thomas A Ravenscroft, Ashleigh Jacobs, Mingxue Gu, et al.
An Initial Experience of Completion Hemispherotomy via Magnetic Resonance-Guided Laser Interstitial Therapy, Vijay M Ravindra, Lucia Ruggieri, Nisha Gadgil, et al.
When Phased without Water: Biophysics of Cellular Desiccation, from Biomolecules to Condensates, Paulette Sofia Romero-Perez, Yanniv Dorone, Eduardo Flores, et al.