The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2022
Reduction of Mutant ATXN1 Rescues Premature Death in a Conditional SCA1 Mouse Model, James P Orengo, Larissa Nitschke, Meike E van der Heijden, et al.
Oxytocin Signaling Is Necessary for Synaptic Maturation of Adult-Born Neurons, Brandon T Pekarek, Mikhail Kochukov, Brittney Lozzi, et al.
Rare Diseases and Space Health: Optimizing Synergies From Scientific Questions To Care, Maria Puscas, Gabrielle Martineau, Gurjot Bhella, et al.
Potential Interactions Between Cerebellar Dysfunction and Sleep Disturbances in Dystonia, Luis E Salazar Leon and Roy V Sillitoe
Sox9 Directs Divergent Epigenomic States in Brain Tumor Subtypes, Debosmita Sardar, Hsiao-Chi Chen, Amanda Reyes, et al.
TFEB Induces Mitochondrial Itaconate Synthesis To Suppress Bacterial Growth in Macrophages, Ev-Marie Schuster, Maximilian W Epple, Katharina M Glaser, et al.
Clinical Exome Sequencing Data Reveal High Diagnostic Yields for Congenital Diaphragmatic Hernia Plus (CDH+) and New Phenotypic Expansions Involving CDH, Tiana M Scott, Ian M Campbell, Andres Hernandez-Garcia, et al.
Recurrent Liponeurocytoma: A Case Report and Systematic Review of the Literature, Darsh S Shah, Himanshu Sharma, Prem Patel, et al.
Distinct Organization of Two Cortico-Cortical Feedback Pathways, Shan Shen, Xiaolong Jiang, Federico Scala, et al.
Reconstructive Outcomes of Multilayered Closure of Large Skull Base Dural Defects Following Open Anterior Craniofacial Resection, Justin Shi, Tokunbo Ayeni, Kathleen Kelly Gallagher, et al.
Chemotherapy Coupled to Macrophage Inhibition Induces T-Cell and B-Cell Infiltration and Durable Regression in Triple-Negative Breast Cancer, Swarnima Singh, Nigel Lee, Diego A Pedroza, et al.
Spatial Analysis of Drug Absorption, Distribution, Metabolism, and Toxicology Using Mass Spectrometry Imaging, Michelle L Spruill, Mirjana Maletic-Savatic, Howard Martin, et al.
Advancements in the Quest to Map, Monitor, and Manipulate Neural Circuitry, Jessica L Swanson, Pey-Shyuan Chin, Juan M Romero, et al.
Activation of Basal Forebrain-to-Lateral Habenula Circuitry Drives Reflexive Aversion and Suppresses Feeding Behavior, Jessica L Swanson, Joshua Ortiz-Guzman, Snigdha Srivastava, et al.
Clinical Diagnosis of Metabolic Disorders Using Untargeted Metabolomic Profiling and Disease-Specific Networks Learned From Profiling Data, Lillian R Thistlethwaite, Xiqi Li, Lindsay C Burrage, et al.
ANKLE2-Related Microcephaly: A Variable Microcephaly Syndrome Resembling Zika Infection, Ajay X Thomas, Nichole Link, Laurie A Robak, et al.
Influence of Data Sampling Methods on the Representation of Neural Spiking Activity In Vivo, Meike E van der Heijden, Amanda M Brown, and Roy V Sillitoe
Quantification of Behavioral Deficits in Developing Mice With Dystonic Behaviors., Meike E Van Der Heijden, Jason S Gill, Alejandro G Rey Hipolito, et al.
Biliverdin Reductase Bridges Focal Adhesion Kinase to Src To Modulate Synaptic Signaling, Chirag Vasavda, Evan R Semenza, Jason Liew, et al.
Identification of the NRF2 Transcriptional Network as a Therapeutic Target for Trigeminal Neuropathic Pain, Chirag Vasavda, Risheng Xu, Jason Liew, et al.
Cancer-Driving Mutations Are Enriched in Genic Regions Intolerant to Germline Variation, Dimitrios Vitsios, Ryan S Dhindsa, Dorota Matelska, et al.
Region-Specific Denoising Identifies Spatial Co-Expression Patterns and Intra-Tissue Heterogeneity in Spatially Resolved Transcriptomics Data, Linhua Wang, Mirjana Maletic-Savatic, and Zhandong Liu
Neuronal Activity Induces Glucosylceramide That Is Secreted via Exosomes for Lysosomal Degradation in Glia, Liping Wang, Guang Lin, Zhongyuan Zuo, et al.
The Clock Modulator Nobiletin Mitigates Astrogliosis-Associated Neuroinflammation and Disease Hallmarks in an Alzheimer’s Disease Model, Marvin Wirianto, Chih-Yen Wang, Eunju Kim, et al.
Role of Drosophila in Human Disease Research 2.0, Masamitsu Yamaguchi and Shinya Yamamoto