The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2026
Uncovering Phenotypic Expansion in AXIN2-Related Disorders through Precision Animal Modeling, Nathalie M Aceves-Ewing, Denise G Lanza, Paul C Marcogliese, et al.
Latent Factor Modeling Reveals Unexpected Spatial Heterogeneity in Human Alzheimer's Disease Brain Transcriptomes, Rami Al-Ouran, Chaozhong Liu, Linhua Wang, et al.
Sex-Specific Differences in Mediobasal Hypothalamus in Response to Nutritional States, Jonathan C Bean, Jinjing Jian, Tzu-Chiao Lu, et al.
Rare Heterozygous De Novo Variants in RAPGEF2 Are Associated With a Neurodevelopmental Disorder, Ali H Bereshneh, Kirkland A Wilson, Xueyang Pan, et al.
A Blended Genome and Exome Sequencing Method Captures Genetic Variation in an Unbiased and Cost-Effective Manner, Toni A Boltz, Benjamin B Chu, Matthew DeFelice, et al.
Rare Heterozygous Missense Variants in VSX2 Are Associated With Retinal Detachment, Daniel C Brock, Justin S Dhindsa, Yifan Chen, et al.
Glutamatergic Projection Neurons in the Basal Forebrain Underlie Learned Olfactory Associational Valence Assignments, Pey-Shyuan Chin, Zhuokun Ding, Mikhail Kochukov, et al.
Cleavage and Polyadenylation Specificity Factor Subunit 5 Regulates Pulmonary Artery Smooth Muscle Expansion and Hypoxic Response, Scott D Collum, Lisha Zhu, Tingting W Mills, et al.
Misregulated Alternative Splicing in Endometriosis: A Role for Aberrant mRNA Variants in Endometriotic Cell Growth, Venkata Naga Goutham Davuluri, Michelle Dias, Roxanna Llinas, et al.
RNAi-Based Screen for Pigmentation in Drosophila melanogaster Reveals Regulators of Brain Dopamine and Sleep, Samantha L Deal, Danqing Bei, Shelley B Gibson, et al.
Mapping the Causal Chain From Genetic Risk Variants to Lipid Dysmetabolism in Parkinson’s Disease, Ruth B De-Paula, Jonggeol Kim, Herve Rhinn, et al.
Limosilactobacillus reuteri Alleviates Proinflammatory T-Cell-Mediated Liver Injury and Transcriptomic Changes in Immunocompromised Mice, Ana Fadhel Alvarez, Zheng Yin, Beanna Okeugo, et al.
Rab4 Spatially and Functionally Converges With Rab7 in the Degradative Endolysosomal Network, Stephen M Farmer, Shiyu Xu, Yue Yu, et al.
The Words Community Dwelling, Spanish-Preferring Mexican/Mexican American Adults Use To Talk About Alzheimer’s Disease and Genetic Testing: Implications for Education and Outreach, Jamie C Fong, Fatima I Chavez, Karla Silos, et al.
Hippo Signaling Regulates Cuticle Pigmentation and Dopamine Metabolism in Drosophila, Shelley B Gibson, Samantha L Deal, Ye-Jin Park, et al.
Leveraging Clinical Sleep Data Across Multiple Pediatric Cohorts for Insights Into Neurodevelopment: The Retrospective Analysis of Sleep in Pediatric (Rasp) Cohorts Study, Naihua N Gong, Aditya Mahat, Samya Ahmad, et al.
Factors Associated With Postpartum Depression Symptoms Following Antepartum Hospitalization, Alison N Goulding, Daniel Palacios, Sukru Aras, et al.
Two Lysosomal Genes ATP13A2 and GBA1 Interact To Drive Neurodegeneration, Mingxue Gu, Jinghan Zhao, Mingxi Deng, et al.
Translational Reading Frame Predicts the Pathogenicity of C-Terminal Frameshift Deletions in MeCP2, Jacky Guy, Elena Hein, Beatrice Alexander-Howden, et al.
Antibiotic Administration After Previable Preterm Prelabor Rupture of Membranes Is Associated With Prolonged Latency, Alexandra L Hammerquist, Alexander M Saucedo, Selina L Bowler, et al.
Multi-Trait and Multi-Ancestry Genetic Analysis of Comorbid Lung Diseases and Traits Improves Genetic Discovery and Polygenic Risk Prediction, Yixuan He, Wenhan Lu, Yon Ho Jee, et al.
Arriving at a Diagnosis: Effective Strategies Used by the Undiagnosed Diseases Network, Somin Hwang, Rachel M Brown, Dustin Baldridge, et al.
Nuclear Export as a Therapeutic Vulnerability in ZFTA-RELA Ependymoma, Siri M Ippagunta, Amir Arabzade, Srinidhi Varadharajan, et al.
Selective and Differential Roles of PVHCRH Neurotransmitters in Diet-Induced Obesity in Mice, Zhiying Jiang, Yuhan Cao, Michelle He, et al.
Dominant Clones Leverage Developmental Epigenomic States To Drive Ependymoma, Alisha S Kardian, Hua Sun, Siri Ippagunta, et al.