Open-access, full-text copies of UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.

Older UT GSBS dissertations (from approximately 1979-1999) are available, in print format only, in The TMC Library. They are listed in the Catalog. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list.

Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.

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Theses/Dissertations from 2018

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Aging Exacerbates Neutrophil Pathogenicity in Ischemic Stroke, Meaghan Roy-O'Reilly

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ASSEMBLY AND DISPLAY OF SURFACE PROTEINS IN ACTINOMYCES ORIS, Sara Siegel

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Attitudes Toward Updated Genetic Testing Among Patients with Unexplained Mismatch Repair Deficiency, Jessica Omark

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AUTO-DELINEATION OF OROPHARYNGEAL CLINICAL TARGET VOLUMES USING DEEP LEARNING TECHNIQUES, Carlos Eduardo Cardenas

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Bayesian Designs for Early Phase Clinical Trials with Novel Target Agents, Heng Zhou

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BIOLOGICAL CLOCKS, INFLAMMATION, AND MULTIORGAN DAMAGE IN SICKLE CELL DISEASE, Morayo Adebiyi

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CHANGES IN THE TESTES FOLLOWING SPINAL CORD INJURY AND THE ATTENUATING EFFECTS OF LICOFELONE, Ryan Fortune

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CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS, Sarah Azam

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CHARACTERIZATION OF METRONIDAZOLE- AND VANCOMYCIN-RESISTANT CLINICAL ISOLATES OF CLOSTRIDIUM DIFFICILE, Chioma Odo

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Characterizing the recognition motif and novel substrates of CARM1, Sitaram gayatri

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Cholinergic Control of Cortical Circuit Activity, Rajan Dasgupta

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Computational insights into the generation of chromosomal copy number changes, Yihua Liu

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CURRENT GENETIC COUNSELING PRACTICE FOLLOWING POSITIVE NON-INVASIVE PRENATAL TESTING FOR SEX CHROMOSOME ABNORMALITIES, Lauren Fleddermann

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DECIPHERING THE ROLES OF ΔNP63 IN REGULATING EPITHELIAL TO MESENCHYMAL TRANSITION, CANCER PROGRESSION AND METASTASIS, Ngoc Bui

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Design, Fabrication, and Validation of 3D Printed, Patient-Specific Compensators for Postmastectomy Radiation Therapy, Daniel Craft

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Development and Characterization of a Bi-specific Antibody Targeting HLA-A2/PR1, Amanda Herrmann

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Development and Commissioning of an Independent Peer Review System for a Small Animal Irradiator, Mary Peters

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DEVELOPMENT AND IMPLEMENTATION OF A HOMOGENEOUS AND A HETEROGENEOUS ANTHROPOMORPHIC END TO END QUALITY ASSURANCE AUDIT SYSTEM PHANTOM FOR MAGNETIC RESONANCE GUIDED RADIOTHERAPY MODALITIES RANGING FROM 0.35 T TO 1.50 T, Angela Steinmann

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DEVELOPMENT OF 3D-PRINTED PATIENT SPECIFIC BOLUS FOR CLINICAL USE IN TOTAL SCALP IRRADIATION, Garrett Baltz

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Discovery and effects of pharmacological inhibition of the E3 ligase Skp2 by small molecule protein-protein interaction disruptors, John K. Morrow

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DISSECTING THE MOLECULAR MECHANISM OF EARLY TUMOR DISSEMINATION IN NON-SMALL CELL LUNG CANCER, Xingtong Liu

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ENHANCING RADIATION SENSITIVITY IN NON-SMALL CELL LUNG CANCER, Yifan Wang

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EPITHELIAL TO MESENCHYMAL TRANSITION AS A PREDICTOR OF RESPONSE TO POLO-LIKE KINASE 1 INHIBITION-INDUCED APOPTOSIS IN NON-SMALL CELL LUNG CARCINOMA, Pavitra Viswanath

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EQUIPMENT TO ADDRESS INFRASTRUCTURE AND HUMAN RESOURCE CHALLENGES FOR RADIOTHERAPY IN LOW-RESOURCE SETTINGS, Rachel McCarroll

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EVALUATION OF PRESAGE® AS A 3D DOSE VERIFICATION TOOL IN PROTON BEAMS, Mitchell Carroll

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EVOLUTION VIA GENE DUPLICATION AND ALTERNATIVE SPLICING IN THE EUKARYOTIC SKI7 AND HBS1 GENES, Alexandra Marshall

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EXAMINING THE RELATIONSHIP BETWEEN GENETIC COUNSELORS’ IMPLICIT ATTITUDES TOWARD DISABILITY AND THEIR PRACTICE METHODS, Helen W. Gould

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FUNCTIONAL HETEROGENEITY OF FIBROBLASTS IN DERMAL WOUND HEALING, Ehsan Ehsanipour

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Functional Similarity of PRD-Containing Virulence Regulators in Bacillus anthracis, Malik Raynor

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GENETIC EVOLUTION AND PROGNOSTIC DETERMINANTS OF PANCREATIC CANCER ON LONGITUDINAL LIQUID BIOPSIES, Vincent Bernard

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GENETIC TESTING PRACTICES OF GENETIC COUNSELORS, GENETICISTS, AND PEDIATRIC NEUROLOGISTS WITH REGARD TO CHILDHOOD-ONSET NEUROGENETIC CONDITIONS, Sara Wofford

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GENOMIC AND TRANSCRIPTOMIC LANDSCAPE OF COLORECTAL PREMALIGNANCY, Kyle Chang

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Genomic Evolution of Chemoresistance in Triple-Negative Breast Cancer Delineated by Single Cell Sequencing, Charissa Kim

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HYPOTHALAMIC CIRCUITS IN THE CONTROL OF FEEDING AND EMOTIONAL BEHAVIORS, Leandra Mangieri

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IDENTIFICATION AND UTILITY OF DNA IN EXOSOMES, Paul Kurywchak

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Identification of Intracranial Lesions with Dual-Energy Computed Tomography and Magnetic Resonance Phase Imaging, Megan C. Jacobsen

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IDENTIFICATION OF TISSUE AND CIRCULATING BIOMARKERS FOR PREMALIGNANT AND MALIGNANT LESIONS, SHU-HONG LIN

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IDENTIFYING MOLECULAR TARGETS AND VALIDATING NOVEL THERAPIES FOR OVARIAN CANCER, Alejandro Villar-Prados

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Identifying Subunit Organization and Function of the Nuclear RNA Exosome Machinery, Jillian Losh

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Improved Target Coverage of Spinal Metastases Through the Use of Flattening Filter Free Beams, Laura Bennett

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INVESTIGATING INVASION IN DUCTAL CARCINOMA IN SITU WITH TOPOGRAPHICAL SINGLE CELL GENOME SEQUENCING, Anna Casasent and Anna Casasent

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INVESTIGATING THE IMPACT OF INTRAGENIC DNA METHYLATION ON GENE EXPRESSION, AND THE CLINICAL IMPLICATIONS ON TUMOR CELLS AND ASSOCIATED STROMA, Michael McGuire

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INVESTIGATING THE ROLES OF TAP63 AND TAP73 IN CUTANEOUS SQUAMOUS CELL CARCINOMA AND LUNG ADENOCARCINOMA, Andrew J. Davis

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INVESTIGATING THE SINGLE CELL HETEROGENEITY AND PHYSIOLOGICAL IMPACT OF MISTRANSLATION, Christopher Evans

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ISCHEMIC STROKE DAMAGE IS REDUCED BY INHIBITION OF IL-6 SIGNALING WITH TOCILIZUMAB, Jacob Hudobenko

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Loss of Rnf43 accelerates Kras-mediated pancreatic neoplasia, Gita Dangol

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Mechanism of Incorporation and Repair of Uracil at Highly Transcribed Genes In Saccharomyces Cerevisiae, Norah Auma Owiti

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MECHANISMS AND TARGETING OF NEURODEVELOPMENTAL REGULATOR REST IN MEDULLOBLASTOMA DISSEMINATION, Keri Callegari

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MICRORNA FUNCTIONS IN UV-INDUCED CUTANEOUS SQUAMOUS CELL CARCINOMA, Tran Nguyen

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miR-484 Functions as an Onco-miR in Triple Negative Breast Cancer, Nashwa Kabil

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Nanoscale Organization of the Small GTPase Rac1, Kelsey Maxwell

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Omics Approaches to Uncover Germline and Somatic Variation Underlying Inherited Sarcomagenesis, Justin Wong

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Outcomes of Genetic Testing in a Genitourinary Genetics Clinic, Annelise Pace

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Patient Attitudes Toward Genetic Testing for Inherited Predispositions to Hematologic Malignancies, Taylor Beecroft

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PHOSPHORYLATION IMPAIRS DICER1 FUNCTION TO ACCELERATE AGING AND TUMORIGENESIS IN VIVO, Neeraj Aryal

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POPULATION CODES AND THEIR CORRELATES IN DECISION MAKING, Neda Shahidi and Neda Shahidi

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PREDICTION OF 1P/19Q CODELETION STATUS IN DIFFUSE GLIOMA PATIENTS USING PREOPERATIVE MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING, Donnie Kim

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Psychiatric Impact of Tuberous Sclerosis Complex and Utilization of Mental Health Treatment, Kate Mowrey

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SIMVASTATIN DOES NOT SENSITIZE IBC3 HER2+ INFLAMMATORY BREAST CANCER BRAIN METASTASES TO WHOLE BRAIN IRRADIATION IN AN IMMUNOCOMPROMISED MOUSE MODEL, Swaminathan Kumar and Wendy A. Woodward

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Somatostatin Receptor 2 Regulation by C-terminal Motifs and PDZ Domain Proteins, Courtney Olsen

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SPHINGOSINE KINASE 1 REGULATES FASCIN EXPRESSION TO PROMOTE METASTASIS IN TRIPLE NEGATIVE BREAST CANCER, Sunil Acharya

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STRUCTURE BASED DRUG DESIGN OF HIGH AFFINITY KRAS INHIBITORS, Michael McCarthy

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The Cross-Talk Between Neurons and Microglia Through Interleukin-4 After Ischemic Injury, Shun-Ming Ting

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The Epithelial To Mesenchymal Transition In Breast Cancer Induces Alterations In Metabolism, Esmeralda Ramirez-Peña

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THE PROTECTIVE EFFECTS OF MEMANTINE ON THE MORPHOLOGY AND ACTIVITY OF IRRADIATED DENDRITIC SPINES, Thanh Lam

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The Regulation of DNA Methylation in Mammalian Development and Cancer, Nicolas Veland

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The Role of Merlin and Apicobasal Polarity in Endometrial Development and Homeostasis, Erin Lopez

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The Role of Perivascular FIbrosis in Post-Stroke Glymphatic Impairment and Cerebral Amyloid Angiopathy, Matthew D. Howe

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The Role of Tumor Suppressor DEAR1 in the Acquisition of Mammary Stem/Progenitor Cell Properties, Uyen Le

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TRICHURIS MURIS WHEY ACIDIC PROTEIN INDUCES TYPE 2 PROTECTIVE IMMUNITY AGAINST WHIPWORM, Neima Briggs

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TRIM24 as an Oncogene in the Mammary Gland, Aundrietta Duncan

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Trim24 in Normal & Malignant Hematopoiesis, Justin Shaw

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TUMOR IMMUNOTHERAPY: MECHANISMS OF ACQUIRED RESISTANCE AND CHARACTERIZATION OF IMMUNE RELATED TOXICITIES, Ashvin Jaiswal

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UBE4B LEVELS DETERMINE THE EFFICACY OF EGFR AND STAT5 INHIBITORS IN TREATMENT RESISTANT NEUROBLASTOMA, David James Savage

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VASCULAR INJURY IN Col3a1+/- MICE MODEL OF VASCULAR EHLER-DANLOS SYNDROME, Ping ZHOU MS

Theses/Dissertations from 2017

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A LICENSE TO KILL: UNDERSTANDING NATURAL KILLER CELL LICENSING TO FIGHT CANCER, Jolie Schafer

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ANALYSIS OF THE BIOCHEMICAL AND CELLULAR ACTIVITIES OF SUBSTRATE BINDING BY THE MOLECULAR CHAPERONE HSP110/SSE1, Veronica M. Garcia

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ANDROGEN RECEPTOR AND PROSTATE CANCER CELL HETEROGENEITY, Qu Deng

A PRECLINICAL STUDY OF RADIATION-INDUCED LUNG TOXICITY WHEN IRRADIATING IN A STRONG MAGNETIC FIELD, Ashley E. Rubinstein

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A tail-based test for differential expression analysis and pathway analysis in RNA-sequencing data, Jiong Chen

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Attitudes of Clinicians Towards Cardiac Surgery and Trisomy 18, Meagan Kaulfus

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Attitudes Toward and Uptake of Prenatal Genetic Screening and Testing in Twin Pregnancies, Kathryn M. Reese

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Barriers to Expansion of Supervision Networks at Genetic Counseling Training Programs, Jordan E. Berg

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CD47+ Exosomes Facilitate Effective Targeting of Oncogenic Kras in Pancreatic Cancer, Sushrut Kamerkar

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CHARACTERIZATION AND REVERSAL OF DOXORUBICIN-MEDIATED CHANGES IN SENSORY NEURONS, Brittany L. Coughlin

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CHARACTERIZATION OF NOTCH1 AND PI3K-PTEN-AKT/mTOR PATHWAY INTERACTION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA, Kyriante' Henry

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CHARACTERIZATION OF THE ROLE OF THE pKM101-ENCODED T4SS OUTER MEMBRANE CORE COMPLEX IN SUBSTRATE TRANSFER, PILUS BIOGENESIS, AND RECIPIENT CELL CONTACT, Jay E. Gordon

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CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING, Natalie Sirisaengtaksin and Natalie Sirisaengtaksin

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Characterizing the source of neutrophil elastase and proteinase 3 cross-presentation in B-cell acute lymphoblastic leukemia, Selena Carmona

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CIRCULATING AUTOANTIBODIES IN HUMAN TRAUMATIC SPINAL CORD INJURY SUBJECTS AND THEIR RELATIONSHIP TO THE DEVELOPMENT OF NEUROPATHIC PAIN, Georgene Hergenroeder

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CLINICAL AND THERAPEUTIC SIGNIFICANCE OF OBESITY IN MELANOMA, Jennifer L. McQuade

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CLINICAL APPLICABILITY OF PROPOSED ALGORITHM FOR IDENTIFYING INDIVIDUALS AT RISK FOR HEREDITARY HEMATOLOGIC MALIGNANCIES, Maggie Clifford

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Computational Identification of Noncoding Driver Mutations Based on Impact on RNA Processing, Kevin Zhu

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Computer-Aided Detection of Pathologically Enlarged Lymph Nodes On Non-Contrast CT In Cervical Cancer Patients For Low-Resource Settings, Brian M. Anderson, Laurence E. Court, Ann Klopp, Stephen F. Kry, Jennifer Johnson, Erik Cressman, Arvind Rao, and Jinzhong Yang

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CONTRASTING EFFECTS OF AN MDM2 FUNCTIONAL POLYMORPHISM ON TUMOR PHENOTYPES, Guadalupe J. Ortiz IV

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Cyclin B1 mediates the effect of UCHL1 in promoting cell cycle progression in uterine papillary serous carcinoma, Suet Ying Kwan

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CYTOPLASMIC CYCLIN E MEDIATES RESISTANCE TO AROMATASE INHIBITORS IN BREAST CANCER, Iman Doostan

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Detecting and Evaluating Therapy Induced Changes in Radiomics Features Measured from Non-Small Cell Lung Cancer to Predict Patient Outcomes, Xenia J. Fave

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DEVELOPING NOVEL APPROACHES TO IMPROVE RESPONSE TO T CELL BASED CANCER IMMUNOTHERAPY, Rina M. Mbofung

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DYNAMIC ASSESSMENT OF NK CELL INTERACTIONS WITH PEDIATRIC TUMOR CELLS TO PREDICT RESPONSE TO IMMUNOTHERAPY, Arianexys Aquino Lopez