Open-access, full-text copies of UT GSBS dissertations from 2009 onwards. Topics include all aspects of the biomedical sciences.

Authors who expect to publish do have the option to withhold full text for a limited period of time. When that has been done, the reader will see a release date posted with the abstract.

Older UT GSBS dissertations (from approximately 1979-1999) are available, in print format only, at McGovern Historical Center. They can be found via OneSearch. Search by subject heading: "Dissertations, Academic--University of Texas Health Science Center at Houston. Graduate School of Biomedical Sciences" for the full list, click DigitalCommons@TMC in the white banner above the search box, or use the main search box to search for known individual dissertations.

Some older GSBS dissertations are also available online via ProQuest, but full-text access is restricted to TMC academic institutions affiliated with The TMC Library.

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Theses/Dissertations from 2019

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An Information Theory Model for Optimizing Quantitative Magnetic Resonance Imaging Acquisitions, Drew Mitchell

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AN OXANTHROQUINONE DERIVATIVE DISRUPTS RAS PLASMA MEMBRANE LOCALIZATION AND FUNCTION BY INHIBITION OF ACYLPEPTIDE HYDROLASE AND PERTURBATION OF SPHINGOMYELIN METABOLISM, Lingxiao Tan

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Commissioning of Micro-Cube Thermoluminescent Dosimeters for Small Field Dosimetry Quality Assurance in Radiotherapy, Brandon Luckett

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COMPUTATIONAL GENOMIC MODELS FOR SPATIO-TEMPORAL INVESTIGATION OF EARLY LUNG CANCER PATHOLOGY, Smruthy Sivakumar

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Cross-presentation Is A Source of Tumor Antigens For Multiple Myeloma Immunotherapy, Alexander A. Perakis

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Current Practices and Perspectives of Genetic Counselors and Reproductive Endocrinologists Regarding Transfer of Mosaic Embryos, Angelica Starnes

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Development of a High-Throughput System for Screening of Anti-Prion Molecules, Katherine Do

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DEVELOPMENT OF AUTOMATED RADIOTHERAPY TREATMENT PLANNING FOR CERVICAL AND BREAST CANCER FOR RESOURCE-CONSTRAINED CLINICS, Kelly Kisling

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Exploring Experiences & Expectations of Prenatal Healthcare and Genetic Counseling/Testing in Immigrant Latinas, Georgiann Garza

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EXPLORING THE POTENTIAL YIELD OF PRENATAL TESTING BY EVALUATING A POSTNATAL POPULATION WITH STRUCTURAL ABNORMALITIES, Peyton Busby

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GENETIC COUNSELOR UTILIZATION AND INTERPRETATION OF SOMATIC TUMOR TESTING IN EVALUATION FOR LYNCH SYNDROME, Danielle Williams

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Higher order chromosome organization and recombination dynamics of meiotic prophase I in mouse spermatocytes, Rhea Kang

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Hsp70-mediated regulation of Hsf1 transcriptional activity in Saccharomyces cerevisiae, Sara Peffer

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Hypoglycemia in Mitochondrial Disorders, Allison Moats

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Identifying Interest in and Barriers to Psychiatric Genetic Counseling, Samantha Montgomery

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Identifying Pathogenic Variants in Hereditary Cancer Syndrome Genes via Tumor Molecular Profiling, Carol Nowlen

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IL-6/JAK1 DRIVES PD-L1 PHOSPHORYLATION AND GLYCOSYLATION TO PROMOTE CANCER IMMUNE EVASION, Li-Chuan Chan

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INVESTIGATING THE ROLE OF THE P63 ISOFORM ΔNP63 IN LUNG STEM CELL POPULATIONS AND LUNG CANCER, Sarah J. Wu

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IPSC BASED GENE CORRECTION AND DISEASE MODEL OF A NEW CLASS OF LGMD DUE TO POGLUT1 MUTATION, Jose Ortiz-Vitali

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Metabolic Control, Quality of Life, and Body Image in Patients with Glycogen Storage Disease Type Ia, Alexa Bream

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Modeling Proton Relative Biological Effectiveness Using Monte Carlo Simulations of Microdosimetry, Mark A. Newpower

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MULTIMODALITY SOMATOSTATIN ANALOG FOR FLUORESCENCE-GUIDED SURGERY IN CANCER, Servando Hernandez Vargas

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Oxidative Phosphorylation: A Critical Feature and Novel Therapeutic Target in Melanoma Brain Metastases, Grant Fischer

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PLATISCITY OF C. ELEGANS GERMLINE STEM CELLS UNDER NUTRITIONAL AND METABOLIC STRESS, Kenneth Trimmer

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QUANTITATIVE IMAGING FOR PRECISION MEDICINE IN HEAD AND NECK CANCER PATIENTS, Rachel Ger

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Rejuvenation of the Epigenetic Landscape of the Aged Brain Through Manipulation of Circulating Factors, Edward Koellhoffer

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ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER, Clinton Yam

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Sequence-Specific Gene Correction of Cystic Fibrosis Airway Basal Cells, Varada Anirudhan

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Termination for Fetal Anomaly: What is The Impact of Genetic Counseling on Coping?, Cayleen Smith

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THE CHARACTERIZATION OF T-CELL MANUFACTURING FOR ADOPTIVE T-CELL THERAPIES, amir ALPERT

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THE GSK-3β-FBXL21 AXIS REGULATES TCAP VIA UBIQUITIN-MEDIATED PROTEASOMAL PATHWAY IN THE CYTOPLASM, Jiah Yang

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The impacts of insurance and billing considerations on the practice and attitudes of genetic counselors, Emily Krosschell

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THE ROLE OF GENE EXPRESSION NOISE IN MAMMALIAN CELL SURVIVAL, Kevin Farquhar

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Thiol-based Misfolding: Linking Redox Balance to Cytosolic Proteostasis, Ford Amy

Theses/Dissertations from 2018

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3D SCINTILLATOR DETECTOR QUENCHING CHARACTERIZATION FOR SCANNING PROTON BEAMS, Fahed Alsanea

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A Compressed Sensing Approach to Detect Immobilized Nanoparticles Using Superparamagnetic Relaxometry, Sara Thrower

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ADENYLYL CYCLASE TYPE 9: REGULATION AND CARDIAC FUNCTION, Tanya A. Baldwin and Tanya A. Baldwin

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Aging Exacerbates Neutrophil Pathogenicity in Ischemic Stroke, Meaghan Roy-O'Reilly

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A ROLE FOR EPAC1 AND EPAC2 IN NOCICEPTOR HYPEREXCITABILITY AND CHRONIC PAIN AFTER SPINAL CORD INJURY, Samantha Berkey

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ASSEMBLY AND DISPLAY OF SURFACE PROTEINS IN ACTINOMYCES ORIS, Sara Siegel

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Attitudes Toward Updated Genetic Testing Among Patients with Unexplained Mismatch Repair Deficiency, Jessica Omark

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AUTO-DELINEATION OF OROPHARYNGEAL CLINICAL TARGET VOLUMES USING DEEP LEARNING TECHNIQUES, Carlos Eduardo Cardenas

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Bayesian Designs for Early Phase Clinical Trials with Novel Target Agents, Heng Zhou

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BAYESIAN INTEGRATIVE ANALYSIS OF OMICS DATA, Youyi Zhang

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Behavioral Insights into Nociceptor Function: A Systematic Approach to Understanding Postsurgical and Neuropathic Pain Mechanisms in Rats, Max Odem

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BIOLOGICAL CLOCKS, INFLAMMATION, AND MULTIORGAN DAMAGE IN SICKLE CELL DISEASE, Morayo Adebiyi

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CHANGES IN THE TESTES FOLLOWING SPINAL CORD INJURY AND THE ATTENUATING EFFECTS OF LICOFELONE, Ryan Fortune

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CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS, Sarah Azam

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CHARACTERIZATION OF METRONIDAZOLE- AND VANCOMYCIN-RESISTANT CLINICAL ISOLATES OF CLOSTRIDIUM DIFFICILE, Chioma Odo

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Characterizing the recognition motif and novel substrates of CARM1, Sitaram gayatri

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Cholinergic Control of Cortical Circuit Activity, Rajan Dasgupta

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Computational insights into the generation of chromosomal copy number changes, Yihua Liu

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CURRENT GENETIC COUNSELING PRACTICE FOLLOWING POSITIVE NON-INVASIVE PRENATAL TESTING FOR SEX CHROMOSOME ABNORMALITIES, Lauren Fleddermann

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DECIPHERING THE ROLES OF ΔNP63 IN REGULATING EPITHELIAL TO MESENCHYMAL TRANSITION, CANCER PROGRESSION AND METASTASIS, Ngoc Bui

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Design, Fabrication, and Validation of 3D Printed, Patient-Specific Compensators for Postmastectomy Radiation Therapy, Daniel Craft

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Development and Characterization of a Bi-specific Antibody Targeting HLA-A2/PR1, Amanda Herrmann

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Development and Commissioning of an Independent Peer Review System for a Small Animal Irradiator, Mary Peters

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DEVELOPMENT AND IMPLEMENTATION OF A HOMOGENEOUS AND A HETEROGENEOUS ANTHROPOMORPHIC END TO END QUALITY ASSURANCE AUDIT SYSTEM PHANTOM FOR MAGNETIC RESONANCE GUIDED RADIOTHERAPY MODALITIES RANGING FROM 0.35 T TO 1.50 T, Angela Steinmann

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DEVELOPMENT OF 3D-PRINTED PATIENT SPECIFIC BOLUS FOR CLINICAL USE IN TOTAL SCALP IRRADIATION, Garrett Baltz

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Discovery and effects of pharmacological inhibition of the E3 ligase Skp2 by small molecule protein-protein interaction disruptors, John K. Morrow

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DISSECTING THE MOLECULAR MECHANISM OF EARLY TUMOR DISSEMINATION IN NON-SMALL CELL LUNG CANCER, Xingtong Liu

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ENHANCING RADIATION SENSITIVITY IN NON-SMALL CELL LUNG CANCER, Yifan Wang

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EPITHELIAL TO MESENCHYMAL TRANSITION AS A PREDICTOR OF RESPONSE TO POLO-LIKE KINASE 1 INHIBITION-INDUCED APOPTOSIS IN NON-SMALL CELL LUNG CARCINOMA, Pavitra Viswanath

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EQUIPMENT TO ADDRESS INFRASTRUCTURE AND HUMAN RESOURCE CHALLENGES FOR RADIOTHERAPY IN LOW-RESOURCE SETTINGS, Rachel McCarroll

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EVALUATION OF PRESAGE® AS A 3D DOSE VERIFICATION TOOL IN PROTON BEAMS, Mitchell Carroll

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EVOLUTION VIA GENE DUPLICATION AND ALTERNATIVE SPLICING IN THE EUKARYOTIC SKI7 AND HBS1 GENES, Alexandra Marshall

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EXAMINING THE RELATIONSHIP BETWEEN GENETIC COUNSELORS’ IMPLICIT ATTITUDES TOWARD DISABILITY AND THEIR PRACTICE METHODS, Helen W. Gould

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FUNCTIONAL HETEROGENEITY OF FIBROBLASTS IN DERMAL WOUND HEALING, Ehsan Ehsanipour

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Functional Similarity of PRD-Containing Virulence Regulators in Bacillus anthracis, Malik Raynor

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GENETIC EVOLUTION AND PROGNOSTIC DETERMINANTS OF PANCREATIC CANCER ON LONGITUDINAL LIQUID BIOPSIES, Vincent Bernard

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GENETIC TESTING PRACTICES OF GENETIC COUNSELORS, GENETICISTS, AND PEDIATRIC NEUROLOGISTS WITH REGARD TO CHILDHOOD-ONSET NEUROGENETIC CONDITIONS, Sara Wofford

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GENOMIC AND TRANSCRIPTOMIC LANDSCAPE OF COLORECTAL PREMALIGNANCY, Kyle Chang

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Genomic Evolution of Chemoresistance in Triple-Negative Breast Cancer Delineated by Single Cell Sequencing, Charissa Kim

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HEME PEROXIDASE HPX-2 PROTECTS CAENORHABDITIS ELEGANS FROM PATHOGENS, Yi Liu

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HYPOTHALAMIC CIRCUITS IN THE CONTROL OF FEEDING AND EMOTIONAL BEHAVIORS, Leandra Mangieri

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IDENTIFICATION AND UTILITY OF DNA IN EXOSOMES, Paul Kurywchak

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Identification of Intracranial Lesions with Dual-Energy Computed Tomography and Magnetic Resonance Phase Imaging, Megan C. Jacobsen

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IDENTIFICATION OF TISSUE AND CIRCULATING BIOMARKERS FOR PREMALIGNANT AND MALIGNANT LESIONS, SHU-HONG LIN

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IDENTIFYING MOLECULAR TARGETS AND VALIDATING NOVEL THERAPIES FOR OVARIAN CANCER, Alejandro Villar-Prados

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Identifying Subunit Organization and Function of the Nuclear RNA Exosome Machinery, Jillian Losh

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IL-1α BLOCKADE REDUCES IMMUNE SUPPRESSION IN THE EARLY TUMOR MICRO-ENVIRONMENT, Brenda Melendez

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Improved Target Coverage of Spinal Metastases Through the Use of Flattening Filter Free Beams, Laura Bennett

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Improving dbNSFP, Mingyao Lu

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INSIGHTS INTO THE REACTIVATION, REGULATION AND ESSENTIALITY OF OXIDATIVE PROTEIN FOLDING PATHWAYS IN ACTINOBACTERIA, Belkys Sanchez

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INTEGRATIVE BIOINFORMATICS APPROACHES TO ELUCIDATING PROSTATE CANCER CELL HETEROGENEITY, PLASTICITY, AND TREATMENT RESPONSE, Hsueh-Ping Chao

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Intratumoral STING Activation Sensitizes Poorly Immunogenic Cancers to Checkpoint Blockade Immunotherapy, Casey Ager

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INVESTIGATING INVASION IN DUCTAL CARCINOMA IN SITU WITH TOPOGRAPHICAL SINGLE CELL GENOME SEQUENCING, Anna Casasent and Anna Casasent

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INVESTIGATING THE IMPACT OF INTRAGENIC DNA METHYLATION ON GENE EXPRESSION, AND THE CLINICAL IMPLICATIONS ON TUMOR CELLS AND ASSOCIATED STROMA, Michael McGuire

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INVESTIGATING THE ROLES OF TAP63 AND TAP73 IN CUTANEOUS SQUAMOUS CELL CARCINOMA AND LUNG ADENOCARCINOMA, Andrew J. Davis

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INVESTIGATING THE SINGLE CELL HETEROGENEITY AND PHYSIOLOGICAL IMPACT OF MISTRANSLATION, Christopher Evans

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Investigation of Novel Virulence Mechanisms in Candida albicans, Elisa Marie Tafoya Vesely

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INVOLVEMENT OF GDAP1 IN THE REGULATION OF MTORC1 ACTIVITY IN A DROSOPHILA MLIV MODEL, Kristen Clemons

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ISCHEMIC STROKE DAMAGE IS REDUCED BY INHIBITION OF IL-6 SIGNALING WITH TOCILIZUMAB, Jacob Hudobenko

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Mechanism of Incorporation and Repair of Uracil at Highly Transcribed Genes In Saccharomyces Cerevisiae, Norah Auma Owiti

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MECHANISMS AND TARGETING OF NEURODEVELOPMENTAL REGULATOR REST IN MEDULLOBLASTOMA DISSEMINATION, Keri Callegari

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MICRORNA FUNCTIONS IN UV-INDUCED CUTANEOUS SQUAMOUS CELL CARCINOMA, Tran Nguyen

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miR-484 Functions as an Onco-miR in Triple Negative Breast Cancer, Nashwa Kabil

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Nanoscale Organization of the Small GTPase Rac1, Kelsey Maxwell

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Omics Approaches to Uncover Germline and Somatic Variation Underlying Inherited Sarcomagenesis, Justin Wong

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Outcomes of Genetic Testing in a Genitourinary Genetics Clinic, Annelise Pace