Journal Articles
Open-access journal articles from McWilliams School of Biomedical Informatics at UTHealth Houston Faculty. School focus areas include Clinical and Cognitive Informatics, Biomedical Engineering, Public Health Informatics, and Translational Biomedical Informatics.
Submissions from 2023
Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex., Mean-Hwan Kim, Cristina Radaelli, Elliot R Thomsen, Deja Monet, Thomas Chartrand, Nikolas L Jorstad, Joseph T Mahoney, Michael J Taormina, Brian Long, Katherine Baker, Trygve E Bakken, Luke Campagnola, Tamara Casper, Michael Clark, Nick Dee, Florence D'Orazi, Clare Gamlin, Brian E Kalmbach, Sara Kebede, Brian R Lee, Lindsay Ng, Jessica Trinh, Charles Cobbs, Ryder P Gwinn, C Dirk Keene, Andrew L Ko, Jeffrey G Ojemann, Daniel L Silbergeld, Staci A Sorensen, Jim Berg, Kimberly A Smith, Philip R Nicovich, Tim Jarsky, Hongkui Zeng, Jonathan T Ting, Boaz P Levi, and Ed Lein
Systematic Investigation of the Homology Sequences Around the Human Fusion Gene Breakpoints in Pan-Cancer - Bioinformatics Study for a Potential Link to MMEJ, Pora Kim, Himansu Kumar, Chengyuan Yang, Ruihan Luo, Jiajia Liu, and Xiaobo Zhou
HSC-Independent Definitive Hematopoiesis Persists Into Adult Life, Michihiro Kobayashi, Haichao Wei, Takashi Yamanashi, Nathalia Azevedo Portilho, Samuel Cornelius, Noemi Valiente, Chika Nishida, Haizi Cheng, Augusto Latorre, W Jim Zheng, Joonsoo Kang, Jun Seita, David J Shih, Jia Qian Wu, and Momoko Yoshimoto
Blockchain-Enabled Immutable, Distributed, and Highly Available Clinical Research Activity Logging System for Federated COVID-19 Data Analysis From Multiple Institutions, Tsung-Ting Kuo, Anh Pham, Maxim E Edelson, Jihoon Kim, Jason Chan, Yash Gupta, and Lucila Ohno-Machado
The Impact of COVID-19 on the Financial Performance of Largest Teaching Hospitals, Karima Lalani, Jeffrey Helton, Francine R Vega, Marylou Cardenas-Turanzas, Tiffany Champagne-Langabeer, and James R Langabeer
Helping Frontline Workers in Texas-A Framework for Resource Development, Karima Lalani, Meredith O'Neal, Simone Lee Joannou, Bhanumathi Gopal, and Tiffany Champagne-Langabeer
Emulate Randomized Clinical Trials Using Heterogeneous Treatment Effect Estimation for Personalized Treatments: Methodology Review and Benchmark, Yaobin Ling, Pulakesh Upadhyaya, Luyao Chen, Xiaoqian Jiang, and Yejin Kim
An End-to-end In-Silico and In-Vitro Drug Repurposing Pipeline for Glioblastoma, Ko-Hong Lin, Jay-Jiguang Zhu, Judith A Smith, Yejin Kim, and Xiaoqian Jiang
Surface Premelting of Ice Far Below the Triple Point, Yulin Lin, Tao Zhou, Nathan D Rosenmann, Lei Yu, Thomas E Gage, Suvo Banik, Arnab Neogi, Henry Chan, Aiwen Lei, Xiao-Min Lin, Martin Holt, Ilke Arslan, and Jianguo Wen
Single-Cell Dna Methylome and 3D Multi-Omic Atlas of the Adult Mouse Brain, Hanqing Liu, Qiurui Zeng, Jingtian Zhou, Anna Bartlett, Bang-An Wang, Peter Berube, Wei Tian, Mia Kenworthy, Jordan Altshul, Joseph R Nery, Huaming Chen, Rosa G Castanon, Songpeng Zu, Yang Eric Li, Jacinta Lucero, Julia K Osteen, Antonio Pinto-Duarte, Jasper Lee, Jon Rink, Silvia Cho, Nora Emerson, Michael Nunn, Carolyn O'Connor, Zhanghao Wu, Ion Stoica, Zizhen Yao, Kimberly A Smith, Bosiljka Tasic, Chongyuan Luo, Jesse R Dixon, Hongkui Zeng, Bing Ren, M Margarita Behrens, and Joseph R Ecker
An Open Natural Language Processing (NLP) Framework for Ehr-Based Clinical Research: A Case Demonstration Using the National COVID Cohort Collaborative (N3c), Sijia Liu, Andrew Wen, Liwei Wang, Huan He, Sunyang Fu, Robert Miller, Andrew Williams, Daniel Harris, Ramakanth Kavuluru, Mei Liu, Noor Abu-El-Rub, Dalton Schutte, Rui Zhang, Masoud Rouhizadeh, John D Osborne, Yongqun He, Umit Topaloglu, Stephanie S Hong, Joel H Saltz, Thomas Schaffter, Emily Pfaff, Christopher G Chute, Tim Duong, Melissa A Haendel, Rafael Fuentes, Peter Szolovits, Hua Xu, and Hongfang Liu
Discovery of Novel 2-Aminopyridine Derivatives As ROS1 and ALK Dual Inhibitors to Combat Drug-Resistant Mutants including ROS1G2032R and ALKG1202R, Siming Liu, Chuan Huang, Chunhui Huang, Yaqi Huang, Yonghuan Yu, Guowu Wu, Fengqiu Guo, Ying Jiang, Shanhe Wan, Zhengguang Zhu, Yuanxin Tian, Jianghua Zhu, and Jiajie Zhang
The Health-Promoting Effects and the Mechanism of Intermittent Fasting, Simin Liu, Min Zeng, Weixi Wan, Ming Huang, Xiang Li, Zixian Xie, Shang Wang, and Yu Cai
Using Ai-Generated Suggestions From ChatGPT to Optimize Clinical Decision Support, Siru Liu, Aileen P Wright, Barron L Patterson, Jonathan P Wanderer, Robert W Turer, Scott D Nelson, Allison B McCoy, Dean F Sittig, and Adam Wright
Braf d594a Mutation Defines a Unique Biological and Immuno-Modulatory Subgroup Associated With Functional CD8+ T Cell Infiltration in Colorectal Cancer, Wenjing Li, Chenyi Zhao, Wenhui Li, Yang Gong, Kaili Ma, Yujie Lu, Xiaowei Liu, Lianjun Zhang, and Feng Guo
Federated Generalized Linear Mixed Models for Collaborative Genome-Wide Association Studies, Wentao Li, Han Chen, Xiaoqian Jiang, and Arif Harmanci
Collagene Enables Privacy-Aware Federated and Collaborative Genomic Data Analysis, Wentao Li, Miran Kim, Kai Zhang, Xiaoquian Jiang, and Arif Harmanci
A Query Engine for Self-Controlled Case Series, With an Application to COVID-19 EHR Data, Xiaojin Li, Yan Huang, Licong Cui, and Guo-Qiang Zhang
The Mechanisms of Nerve Injury Caused by Viral Infection in the Occurrence of Gastrointestinal Motility Disorder-Related Diseases, Yaqian Li, Qiuyu Chen, Liwei Wang, Xin Chen, Bangmao Wang, and Weilong Zhong
Prediction of Brain Metastases Development in Patients With Lung Cancer by Explainable Artificial Intelligence From Electronic Health Records, Zhao Li, Rongbin Li, Yujia Zhou, Laila Rasmy, Degui Zhi, Ping Zhu, Antonio Dono, Xiaoqian Jiang, Hua Xu, Yoshua Esquenazi, and W Jim Zheng
A Novel Integrated Approach to Predicting Cancer Immunotherapy Efficacy, Ruihan Luo, Jacqueline Chyr, Jianguo Wen, Yanfei Wang, Weiling Zhao, and Xiaobo Zhou
Survey of West Nile and Banzi Viruses in Mosquitoes, South Africa, 2011-2018, Caitlin MacIntyre, Milehna Mara Guarido, Megan Amy Riddin, Todd Johnson, Leo Braack, Maarten Schrama, Erin Gorsich, Antonio Paulo Gouveia Almeida, and Marietjie Venter
Automated Large Vessel Occlusion Detection Software and Thrombectomy Treatment Times: a Cluster Randomized Clinical Trial, Juan Carlos Martinez-Gutierrez, Youngran Kim, Sergio Salazar-Marioni, Muhammad Bilal Tariq, Rania Abdelkhaleq, Arash Niktabe, Anjan N Ballekere, Ananya S Iyyangar, Mai Le, Hussain Azeem, Charles C Miller, Jon E Tyson, Sandi Shaw, Peri Smith, Mallory Cowan, Isabel Gonzales, Louise D McCullough, Andrew D Barreto, Luca Giancardo, and Sunil A Sheth
Contextual Variation of Clinical Notes induced by EHR Migration, Kurt Miller, Sungrim Moon, Sunyang Fu, and Hongfang Liu
Developing Electronic Clinical Quality Measures to Assess the Cancer Diagnostic Process, Daniel R Murphy, Andrew J Zimolzak, Divvy K Upadhyay, Li Wei, Preeti Jolly, Alexis Offner, Dean F Sittig, Saritha Korukonda, Riyaa Murugaesh Rekha, and Hardeep Singh