Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2022
PRUNE1 c.933G>A Synonymous Variant Induces Exon 7 Skipping, Disrupts the DHHA2 Domain, and Leads to an Atypical NMIHBA Syndrome Presentation: Case Report and Review of the Literature, Christina L Magyar, David R Murdock, Lindsay C Burrage, et al.
‘Fly-ing’ From Rare to Common Neurodegenerative Disease Mechanisms, Mengqi Ma, Matthew J Moulton, Shenzhao Lu, et al.
De Novo FZR1 Loss-of-Function Variants Cause Developmental and Epileptic Encephalopathies, Sathiya N Manivannan, Jolien Roovers, Noor Smal, et al.
Drosophila Functional Screening of De Novo Variants in Autism Uncovers Damaging Variants and Facilitates Discovery of Rare Neurodevelopmental Diseases, Paul C Marcogliese, Samantha L Deal, Jonathan Andrews, et al.
Loss of IRF2BPL Impairs Neuronal Maintenance Through Excess Wnt Signaling, Paul C Marcogliese, Debdeep Dutta, Shrestha Sinha Ray, et al.
Why Study Mechanisms of Brain Stimulation Therapies? To Modulate the Right Neurons, in the Right Way, at the Right Time, Matthew J McGinley and Steven T Lee
Discovery of Potent BET Bromodomain 1 Stereoselective Inhibitors Using DNA-Encoded Chemical Library Selections, Ram K Modukuri, Zhifeng Yu, Zhi Tan, et al.
Cleavage Stimulating Factor 64 Depletion Mitigates Cardiac Fibrosis Through Alternative Polyadenylation, Rahul Neupane, Keith Youker, Hari Krishna Yalamanchili, et al.
Expression of 4E-BP1 in Juvenile Mice Alleviates mTOR-Induced Neuronal Dysfunction and Epilepsy, Lena H Nguyen, Youfen Xu, Travorn Mahadeo, et al.
Notch Missense Mutations in Drosophila Reveal Functions of Specific EGF-like Repeats in Notch Folding, Trafficking, and Signaling, Hilman Nurmahdi, Mao Hasegawa, Elzava Yuslimatin Mujizah, et al.
Reduction of Mutant ATXN1 Rescues Premature Death in a Conditional SCA1 Mouse Model, James P Orengo, Larissa Nitschke, Meike E van der Heijden, et al.
Oxytocin Signaling Is Necessary for Synaptic Maturation of Adult-Born Neurons, Brandon T Pekarek, Mikhail Kochukov, Brittney Lozzi, et al.
Potential Interactions Between Cerebellar Dysfunction and Sleep Disturbances in Dystonia, Luis E Salazar Leon and Roy V Sillitoe
Sox9 Directs Divergent Epigenomic States in Brain Tumor Subtypes, Debosmita Sardar, Hsiao-Chi Chen, Amanda Reyes, et al.
TFEB Induces Mitochondrial Itaconate Synthesis To Suppress Bacterial Growth in Macrophages, Ev-Marie Schuster, Maximilian W Epple, Katharina M Glaser, et al.
Clinical Exome Sequencing Data Reveal High Diagnostic Yields for Congenital Diaphragmatic Hernia Plus (CDH+) and New Phenotypic Expansions Involving CDH, Tiana M Scott, Ian M Campbell, Andres Hernandez-Garcia, et al.
Recurrent Liponeurocytoma: A Case Report and Systematic Review of the Literature, Darsh S Shah, Himanshu Sharma, Prem Patel, et al.
Distinct Organization of Two Cortico-Cortical Feedback Pathways, Shan Shen, Xiaolong Jiang, Federico Scala, et al.
Reconstructive Outcomes of Multilayered Closure of Large Skull Base Dural Defects Following Open Anterior Craniofacial Resection, Justin Shi, Tokunbo Ayeni, Kathleen Kelly Gallagher, et al.
Chemotherapy Coupled to Macrophage Inhibition Induces T-Cell and B-Cell Infiltration and Durable Regression in Triple-Negative Breast Cancer, Swarnima Singh, Nigel Lee, Diego A Pedroza, et al.
Spatial Analysis of Drug Absorption, Distribution, Metabolism, and Toxicology Using Mass Spectrometry Imaging, Michelle L Spruill, Mirjana Maletic-Savatic, Howard Martin, et al.
Advancements in the Quest to Map, Monitor, and Manipulate Neural Circuitry, Jessica L Swanson, Pey-Shyuan Chin, Juan M Romero, et al.
Activation of Basal Forebrain-to-Lateral Habenula Circuitry Drives Reflexive Aversion and Suppresses Feeding Behavior, Jessica L Swanson, Joshua Ortiz-Guzman, Snigdha Srivastava, et al.
Clinical Diagnosis of Metabolic Disorders Using Untargeted Metabolomic Profiling and Disease-Specific Networks Learned From Profiling Data, Lillian R Thistlethwaite, Xiqi Li, Lindsay C Burrage, et al.
ANKLE2-Related Microcephaly: A Variable Microcephaly Syndrome Resembling Zika Infection, Ajay X Thomas, Nichole Link, Laurie A Robak, et al.