Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2023
Decreasing Mutant ATXN1 Nuclear Localization Improves a Spectrum of SCA1-Like Phenotypes and Brain Region Transcriptomic Profiles, Hillary P Handler, Lisa Duvick, Jason S Mitchell, et al.
SPA-STOCSY: An Automated Tool for Identifying Annotated and Non-annotated Metabolites in High-Throughput NMR Spectra, Xu Han, Wanli Wang, Li-Hua Ma, et al.
An Altered Extracellular Matrix-Integrin Interface Contributes to Huntington’s Disease-Associated CNS Dysfunction in Glial and Vascular Cells, Sarah J Hernandez, Ryan G Lim, Tarik Onur, et al.
A De Novo Missense Variant in EZH1 Associated With Developmental Delay Exhibits Functional Deficits in Drosophila melanogaster, Sharayu V Jangam, Lauren C Briere, Kristy L Jay, et al.
DNA-Encoded Chemical Libraries Yield Non-covalent and Non-peptidic SARS-CoV-2 Main Protease Inhibitors, Ravikumar Jimmidi, Srinivas Chamakuri, Shuo Lu, et al.
Rare Variant Enrichment Analysis Supports GREB1L as a Contributory Driver Gene in the Etiology of Mayer-Rokitansky-Küster-Hauser Syndrome, Angad Jolly, Haowei Du, Christelle Borel, et al.
Hematopoietic Stem and Progenitor Cells Confer Cross-Protective Trained Immunity in Mouse Models, Bailee N Kain, Brandon T Tran, Pamela N Luna, et al.
Even Heterozygous Loss of CDKN2A/B Greatly Accelerates Recurrence in Aggressive Meningioma, A Basit Khan, Collin W English, William C Chen, et al.
Evolutionarily Conserved Regulators of Tau Identify Targets for New Therapies, Jiyoen Kim, Maria de Haro, Ismael Al-Ramahi, et al.
Clinical Genome Sequencing: Three Years’ Experience at a Tertiary Children’s Hospital, Runjun D Kumar, Lisa F Saba, Haley Streff, et al.
Antisense Oligonucleotide Therapy Rescues Disturbed Brain Rhythms and Sleep in Juvenile and Adult Mouse Models of Angelman Syndrome, Dongwon Lee, Wu Chen, Heet Naresh Kaku, et al.
Automating the High-Throughput Screening of Protein-Based Optical Indicators and Actuators, Jihwan Lee, Beatriz Campillo, Shaminta Hamidian, et al.
The Melanocortin Action Is Biased Toward Protection From Weight Loss in Mice, Hongli Li, Yuanzhong Xu, Yanyan Jiang, et al.
Integration of Transcriptome-Wide Association Study With Neuronal Dysfunction Assays Provides Functional Genomics Evidence for Parkinson’s Disease Genes, Jiayang Li, Bismark Kojo Amoh, Emma McCormick, et al.
Exploring Therapeutic Strategies for Infantile Neuronal Axonal Dystrophy (INAD/PARK14), Guang Lin, Burak Tepe, Geoff McGrane, et al.
Single-Cell Multi-Omics Integration for Unpaired Data by a Siamese Network with Graph-Based Contrastive Loss, Chaozhong Liu, Linhua Wang, and Zhandong Liu
Aging Fly Cell Atlas Identifies Exhaustive Aging Features at Cellular Resolution, Tzu-Chiao Lu, Maria Brbić, Ye-Jin Park, et al.
Co-Transmitting Interneurons in the Mouse Olfactory Bulb Regulate Olfactory Detection and Discrimination, Ariel M Lyons-Warren, Evelyne K Tantry, Elizabeth H Moss, et al.
Cell-based Noninvasive Prenatal Testing (cbNIPT)-A Review on the Current Developments and Future Prospects, Mohamad Ali Maktabi, Liesbeth Vossaert, and Ignatia B Van den Veyver
The Fly Homolog of SUPT16H, a Gene Associated With Neurodevelopmental Disorders, Is Required in a Cell-Autonomous Fashion for Cell Survival, Mengqi Ma, Xi Zhang, Yiming Zheng, et al.
Prevalence of Pathogenic Germline Variants in Adult-Type Diffuse Glioma, Malcolm F McDonald, Lyndsey L Prather, Cassandra R Helfer, et al.
Cellular Composition and Circuit Organization of the Locus Coeruleus of Adult Mice, Andrew McKinney, Ming Hu, Amber Hoskins, et al.
Effects of Protein-Coding Variants on Blood Metabolite Measurements and Clinical Biomarkers in the UK Biobank, Abhishek Nag, Ryan S Dhindsa, Lawrence Middleton, et al.
TFEB-Mediated Lysosomal Exocytosis Alleviates High-Fat Diet-Induced Lipotoxicity in the Kidney, Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, et al.
Social Behavioral Impairments in SYNGAP1-Related Intellectual Disability, Hajer Naveed, Maria McCormack, and J Lloyd Holder