Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2023
Mutations in the Transcriptional Regulator MeCP2 Severely Impact Key Cellular and Molecular Signatures of Human Astrocytes During Maturation, Jialin Sun, Sivan Osenberg, Austin Irwin, et al.
Bi-Allelic Variants in INTS11 Are Associated With a Complex Neurological Disorder, Burak Tepe, Erica L Macke, Marcello Niceta, et al.
A Comprehensive and Integrative Approach to MeCP2 Disease Transcriptomics, Alexander J Trostle, Lucian Li, Seon-Young Kim, et al.
The Lysosomal Ragulator Complex Activates NLRP3 Inflammasome In Vivo via HDAC6, Kohei Tsujimoto, Tatsunori Jo, Daiki Nagira, et al.
International Society for Prenatal Diagnosis 2022 Debate 3-Fetal Genome Sequencing Should Be Offered to All Pregnant Patients, Ignatia B Van den Veyver, Yuval Yaron, and Zandra C Deans
Glutamatergic Cerebellar Neurons Differentially Contribute to the Acquisition of Motor and Social Behaviors, Meike E van der Heijden, Alejandro G Rey Hipolito, Linda H Kim, et al.
Cerebellar Dysfunction in Rodent Models With Dystonia, Tremor, and Ataxia, Meike E van der Heijden and Roy V Sillitoe
Labeling PIEZO2 Activity in the Peripheral Nervous System, Nicholas W Villarino, Yasmeen M F Hamed, Britya Ghosh, et al.
Daam2 Phosphorylation by CK2α Negatively Regulates Wnt Activity During White Matter Development and Injury, Chih-Yen Wang, Zhongyuan Zuo, Juyeon Jo, et al.
CoRegNet: Unraveling Gene Co-Regulation Networks from Public RNA-Seq Repositories Using a Beta-Binomial Statistical Model, Jiasheng Wang, Ying-Wooi Wan, Rami Al-Ouran, et al.
Dicarboxylic Acylcarnitine Biomarkers in Peroxisome Biogenesis Disorders, Michael F Wangler, Barbara Lesko, Rejwi Dahal, et al.
Unravelling Spatial Gene Associations With SEAGAL: A Python Package for Spatial Transcriptomics Data Analysis and Visualization, Linhua Wang, Chaozhong Liu, Yang Gao, et al.
A Cross-Species Proteomic Map Reveals Neoteny of Human Synapse Development, Li Wang, Kaifang Pang, Li Zhou, et al.
Atoh1 Drives the Heterogeneity of the Pontine Nuclei Neurons and Promotes Their Differentiation, Sih-Rong Wu, Jessica C Butts, Matthew S Caudill, et al.
The Atoh1-Cre Knock-In Allele Ectopically Labels a Subpopulation of Amacrine Cells and Bipolar Cells in Mouse Retina, Sih-Rong Wu and Huda Y Zoghbi
Tau Polarizes an Aging Transcriptional Signature to Excitatory Neurons and Glia, Timothy Wu, Jennifer M Deger, Hui Ye, et al.
Lateral Septum as a Melanocortin Downstream Site in Obesity Development, Yuanzhong Xu, Zhiying Jiang, Hongli Li, et al.
Genetics and Pathogenesis of Parkinson's Syndrome, Hui Ye, Laurie A Robak, Meigen Yu, et al.
In Vivo Functional Characterization of Egfr Variants Identifies Novel Drivers of Glioblastoma, Kwanha Yu, Kathleen Kong, Brittney Lozzi, et al.
Functional Screening of Lysosomal Storage Disorder Genes Identifies Modifiers of Alpha-Synuclein Neurotoxicity, Meigen Yu, Hui Ye, Ruth B De-Paula, et al.
Targeting GBM With an Oncolytic Picornavirus Svv-001 Alone and in Combination With Fractionated Radiation in a Novel Panel of Orthotopic PDX Models, Huiyuan Zhang, Yuchen Du, Lin Qi, et al.
Reprogramming Tumour-Associated Macrophages To Outcompete Cancer Cells, Xian Zhang, Shun Li, Isha Malik, et al.
A Novel Pathogenic Mutation of MeCP2 Impairs Chromatin Association Independent of Protein Levels, Jian Zhou, Claudia Cattoglio, Yingyao Shao, et al.
Submissions from 2022
The TFEB-TGIF1 Axis Regulates EMT in Mouse Epicardial Cells, Elena Astanina, Gabriella Doronzo, Davide Corà, et al.
A Role for Insulin-Like Growth Factor 1 in the Generation of Epileptic Spasms in a Murine Model, Carlos J Ballester-Rosado, John T Le, Trang T Lam, et al.