Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2022
The Recurrent De Novo c.2011C>T Missense Variant in MTSS2 Causes Syndromic Intellectual Disability, Yan Huang, Gabrielle Lemire, Lauren C Briere, et al.
Novel Dominant and Recessive Variants in Human ROBO1 Cause Distinct Neurodevelopmental Defects Through Different Mechanisms, Yan Huang, Mengqi Ma, Xiao Mao, et al.
Co-Transmitting Neurons in the Lateral Septal Nucleus Exhibit Features of Neurotransmitter Switching, Patrick J Hunt, Mikhail Kochukov, Brandon T Pekarek, et al.
Racial and Socioeconomic Disparities in Patients With Meningioma: A Retrospective Cohort Study, Hudin N Jackson, Caroline C Hadley, A Basit Khan, et al.
Removal of KCNQ2 From Parvalbumin-Expressing Interneurons Improves Anti-Seizure Efficacy of Retigabine, Junzhan Jing, Corrinne Dunbar, Alina Sonesra, et al.
Oleic Acid Is an Endogenous Ligand of Tlx/NR2E1 That Triggers Hippocampal Neurogenesis, Prasanna Kandel, Fatih Semerci, Rachana Mishra, et al.
Wide Range of Phenotypic Severity in Individuals With Late Truncations Unique to the Predominant CDKL5 Transcript in the Brain, Laura Keehan, Isabel Haviland, Yoel Gofin, et al.
Epithelial Morphogenesis in the Drosophila Egg Chamber Requires Parvin and ILK, Athina Keramidioti, Evgenia Golegou, Eleni Psarra, et al.
Information Is Power: The Experiences, Attitudes and Needs of Individuals Who Chose To Have Prenatal Genomic Sequencing for Fetal Anomalies, Catherine G Kernie, Julia Wynn, Allison Rosenbaum, et al.
ROR Activation by Nobiletin Enhances Antitumor Efficacy via Suppression of IκB/NF-κB Signaling in Triple-Negative Breast Cancer, Eunju Kim, Yoon-Jin Kim, Zhiwei Ji, et al.
Identification of Risk Genes for Alzheimer’s Disease by Gene Embedding, Yashwanth Lagisetty, Thomas Bourquard, Ismael Al-Ramahi, et al.
A Combined Conduit-Bioactive Hydrogel Approach for Regeneration of Transected Sciatic Nerves, Cheuk Sun Edwin Lai, Viridiana Leyva-Aranda, Victoria H Kong, et al.
Comparison of Treadmill Gait Between a Pediatric-Aged Individual With SYNGAP1-Related Intellectual Disability and a Fraternal Twin, Charles S Layne, Christopher A Malaya, David R Young, et al.
Cross-Species Genetic Screens Identify Transglutaminase 5 as a Regulator of Polyglutamine-Expanded Ataxin-1, Won-Seok Lee, Ismael Al-Ramahi, Hyun-Hwan Jeong, et al.
Neurobehavioral Deficits and a Progressive Ictogenesis in the Tetrodotoxin Model of Epileptic Spasms, John T Le, Carlos J Ballester-Rosado, James D Frost, et al.
Kctd7 Deficiency Induces Myoclonic Seizures Associated With Purkinje Cell Death and Microvascular Defects, Justine H Liang, Jonathan Alevy, Viktor Akhanov, et al.
Fly Cell Atlas: A Single-Nucleus Transcriptomic Atlas of the Adult Fruit Fly, Hongjie Li, Jasper Janssens, Maxime De Waegeneer, et al.
The Allergy Mediator Histamine Confers Resistance to Immunotherapy in Cancer Patients via Activation of the Macrophage Histamine Receptor H1, Hongzhong Li, Yi Xiao, Qin Li, et al.
Causal Evidence for a Role of Cerebellar Lobulus Simplex in Prefrontal-Hippocampal Interaction in Spatial Working Memory Decision-Making, Yu Liu, Samuel S McAfee, Meike E Van Der Heijden, et al.
Loss-of-Function Variants in TIAM1 Are Associated With Developmental Delay, Intellectual Disability, and Seizures, Shenzhao Lu, Rebecca Hernan, Paul C Marcogliese, et al.
De Novo Variants in FRMD5 Are Associated With Developmental Delay, Intellectual Disability, Ataxia, and Abnormalities of Eye Movement, Shenzhao Lu, Mengqi Ma, Xiao Mao, et al.
Sensory Processing Phenotypes in Phelan-McDermid Syndrome and SYNGAP1-Related Intellectual Disability, Ariel M Lyons-Warren, Maria C McCormack, and Jimmy L Holder
Cluster Analysis of Short Sensory Profile Data Reveals Sensory-Based Subgroups in Autism Spectrum Disorder, Ariel M Lyons-Warren, Michael F Wangler, and Ying-Wooi Wan
Sex-Specific Epigenetic Development in the Mouse Hypothalamic Arcuate Nucleus Pinpoints Human Genomic Regions Associated With Body Mass Index, Harry MacKay, Chathura J Gunasekara, Kit-Yi Yam, et al.
Lower Fetal Fraction in Clinical Cell-Free DNA (cfDNA) Screening Results is Associated with Increased Risk of Hypertensive Disorders of Pregnancy, Deeksha Madala, Mohamad Ali Maktabi, Riwa Sabbagh, et al.