The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2026
Corticotropin-Releasing Factor Neurons in the Bed Nucleus of the Stria Terminalis Modulate Avoidance Behaviors and Feeding, Juan Manuel Romero, Shae-Marie Stafford-Trujillo, Mitzy Mendoza, et al.
The Filamentous Ultrastructure of the PopZ Condensate Is Required for Its Cellular Function, Daniel Scholl, Tumara Boyd, Andrew P Latham, et al.
Tractor Workflow: A Scalable Nextflow Framework for Local Ancestry-Aware Genome-Wide Association Studies, Nirav N Shah, Taotao Tan, Jessica Honorato-Mauer, et al.
Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics, Janani Subramaniam, Venkata Jonnakuti, Scott D Collum, et al.
Using the Linear References From the Pangenome To Discover Missing Autism Variants, Yang Sui, Jiadong Lin, Michelle D Noyes, et al.
Extending Genome-Wide Association Studies to Admixed Cohorts With High Degrees of Relatedness, Taotao Tan, Alejandra Vergara-Lope, José Jaime Martínez-Magaña, et al.
Modulating Alternative Splicing of MECP2 Is a Potential Therapeutic Strategy for Rett Syndrome, Harini P Tirumala, Li Wang, Yan Li, et al.
Telethon Undiagnosed Disease Program: Structured Approach to Solving Rare Childhood-Onset Genetic Diseases, Annalaura Torella, Manuela Morleo, Carmine Spampanato, et al.
Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers, Utkarsh Tripathi, Masayoshi Suda, Vagisha Kulshreshtha, et al.
Pathogenesis of Polyglutamine Diseases: Piecing Together a Complex Molecular Puzzle, Esmeralda Villavicencio Gonzalez and Huda Y Zoghbi
Evaluating the Utility of RNAseq in Prenatal Diagnostics: Expression Profiles of Cultured Chorionic Villus and Amniotic Fluid Samples, Maria C Vladoiu, Sen Zhao, Roni Zemet, et al.
Application of a Natural Language Processing Algorithm to Early Asthma Ascertainment for Adults in the Era of Electronic Health Records, Chung-Il Wi, Thanai Pongdee, Hee Yun Seol, et al.
TEAD-Independent Mechanisms of YAP Function in Cardiomyocyte Cell Cycle Reentry, Bing Xie, Jeffrey Steimle, Vaibhav Deshmukh, et al.
Non-Synaptic Function and Localization of Syntaxin-Binding Protein 1 in a Mouse Model of STXBP1-Related Epileptic Encephalopathy, Tao Yang, Rajat Banerjee, Yamei Deng, et al.
Shared Neural Geometries for Bilingual Semantic Representations in Human Hippocampal Neurons, Xinyuan Yan, Ana G Chavez, Melissa Franch, et al.
Systems Genetic Dissection of Brain Gene Expression Reveals Excitotoxic Mechanisms of Alzheimer’s Disease, Pinghan Zhao, Omar El Fadel, Anh Le, et al.
Author Correction: Phenome-Wide Analysis of Copy Number Variants in 470,727 UK Biobank Genomes, Xueqing Zoe Zou, Fengyuan Hu, Haiyi Lou, et al.
Phenome-Wide Analysis of Copy Number Variants in 470,727 UK Biobank Genomes, Xueqing Zoe Zou, Fengyuan Hu, Haiyi Lou, et al.
Submissions from 2025
The Psychiatric Genomics Consortium: Discoveries and Directions, Arpana Agrawal, Cynthia M Bulik, Dawit Shawel Abebe, et al.
Injectable Microparticle-Nanoliposome Hydrogel for Extended Release of Small Hydrophilic Molecules, Gil Aizik, Wonmin Choi, Claire A Ostertag-Hill, et al.
ATG Conjugation-Dependent/Independent Mechanisms Underlie Lysosomal Stress-Induced TFEB Regulation, Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, et al.
Current Practices in the Study of Biomolecular Acondensates: A Community Comment, Simon Alberti, Paolo Arosio, Robert B Best, et al.
Plasma lipidome dysregulation in frontotemporal dementia reveals shared, genotype-specific, and severity-linked alterations., Yohannes A Ambaw, Peter A Ljubenkov, Shubham Singh, et al.
Maternal Loss of Mouse Nlrp2 Alters the Transcriptome and DNA Methylome in Gv Oocytes and Impairs Zygotic Genome Activation in Embryos, Zahra Anvar, Michael D Jochum, Imen Chakchouk, et al.
Prenatal Metabolomics Analysis and Fetal Congenital Anomalies and Genetic Conditions: A Review of Current Literature, Sarah Araji, Onur Turkoglu, Mohamad Ali Maktabi, et al.