Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2025
New Insights Into Epileptic Spasm Generation and Treatment From the TTX Animal Model, John W Swann, Carlos J Ballester-Rosado, and Chih-Hong Lee
The Biological Intersection Between Chemotherapy-Related Cognitive Impairment and Alzheimer Disease, Matthew Torre, Camila A Zanella, and Mel B Feany
Biliverdin Reductase A Is a Major Determinant of Protective NRF2 Signaling, Chirag Vasavda, Ruchita Kothari, Navneet Ammal Kaidery, et al.
Drosophila Models Uncover Substrate Channeling Effects on Phospholipids and Sphingolipids in Peroxisomal Biogenesis Disorders, Michael F Wangler, Yu-Hsin Chao, Mary Roth, et al.
ReSort Enhances Reference-Based Cell Type Deconvolution for Spatial Transcriptomics Through Regional Information Integration, Linhua Wang, Ling Wu, Guantong Qi, et al.
The cGAS/STING Pathway: Friend or Foe in Regulating Cardiomyopathy, Weiyue Wang, Yuanxu Gao, Hyun Kyoung Lee, et al.
De Novo Variants in Rybp Are Associated With a Severe Neurodevelopmental Disorder and Congenital Anomalies, Monika Weisz-Hubshman, Lindsay C Burrage, Sharayu V Jangam, et al.
Alzheimer’s Disease Protective Allele of Clusterin Modulates Neuronal Excitability Through Lipid-Droplet-Mediated Neuron-Glia Communication, Xiaojie Zhao, Yan Li, Siwei Zhang, et al.
Submissions from 2024
The DDHD2-STXBP1 Interaction Mediates Long-Term Memory via Generation of Saturated Free Fatty Acids, Isaac O Akefe, Saber H Saber, Benjamin Matthews, et al.
CPSF3 Inhibition Blocks Pancreatic Cancer Cell Proliferation Through Disruption of Core Histone mRNA Processing, Abdulrahman A Alahmari, Aditi H Chaubey, Venkata S Jonnakuti, et al.
TFEB Drives mTORC1 Hyperactivation and Kidney Disease in Tuberous Sclerosis Complex, Nicola Alesi, Damir Khabibullin, Dean M Rosenthal, et al.
Individualized Functional Magnetic Resonance Imaging Neuromodulation Enhances Visuospatial Perception: A Proof-of-Concept Study, Anthony Allam, Vincent Allam, Sandy Reddy, et al.
Individualized Functional Magnetic Resonance Imaging Neuromodulation Enhances Visuospatial Perception: A Proof-of-Concept Study, Anthony Allam, Vincent Allam, Sandy Reddy, et al.
MECP2-Related Disorders While Gene-Based Therapies Are on the Horizon, Katherine Allison, Mirjana Maletic-Savatic, and Davut Pehlivan
Comparison of Four Protocols for In Vitro Differentiation of Human Embryonic Stem Cells into Trophoblast Lineages by BMP4 and Dual Inhibition of Activin/Nodal and FGF2 Signaling, Zahra Anvar, Imen Chakchouk, Momal Sharif, et al.
Oligodendroglial Fatty Acid Metabolism as a Central Nervous System Energy Reserve, Ebrahim Asadollahi, Andrea Trevisiol, Aiman S Saab, et al.
Benchmarking Signal Quality and Spatiotemporal Distribution of Interictal Spikes In Prolonged Human Ieeg Recordings Using Cortec Wireless Brain Interchange, Amir Hossein Ayyoubi, Behrang Fazli Besheli, Michael M Quach, et al.
Modeling Antisense Oligonucleotide Therapy in MECP2 Duplication Syndrome Human iPSC-Derived Neurons Reveals Gene Expression Programs Responsive to MeCP2 Levels, Sameer S Bajikar, Yehezkel Sztainberg, Alexander J Trostle, et al.
Signaling Mechanisms Underlying Activity-Dependent Integration of Adult-Born Neurons in the Mouse Olfactory Bulb, Suyang Bao, Juan M Romero, Benjamin D W Belfort, et al.
Single-Cell Multi-Omic Analysis of the Vestibular Schwannoma Ecosystem Uncovers a Nerve Injury-Like State, Thomas F Barrett, Bhuvic Patel, Saad M Khan, et al.
Leveraging the T2T Assembly to Resolve Rare and Pathogenic Inversions in Reference Genome Gaps, Kristine Bilgrav Saether, Jesper Eisfeldt, Jesse D Bengtsson, et al.
Targeted Accurate RNA Consensus Sequencing (tARC-Seq) Reveals Mechanisms of Replication Error Affecting SARS-CoV-2 Divergence, Catherine C Bradley, Chen Wang, Alasdair J E Gordon, et al.
Parkinson's Disease and Other Alzheimer's Disease and Related Dementia Pathologies and the Progression of Parkinsonism in Older Adults, Aron S Buchman, Lei Yu, Shahram Oveisgharan, et al.
A Single-Cell Transcriptomic Map of the Developing Atoh1 Lineage Identifies Neural Fate Decisions and Neuronal Diversity in the Hindbrain, Jessica C Butts, Sih-Rong Wu, Mark A Durham, et al.
An Excitatory Projection from the Basal Forebrain to the Ventral Tegmental Area That Underlies Anorexia-Like Phenotypes, Jing Cai, Yanyan Jiang, Yuanzhong Xu, et al.