Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2025
Recurrent Carotid Paragangliomas in a Syndromic Patient With a Heterozygous Missense Variant in DNA Methyltransferase 3 Alpha, Ryan J German, Blake Vuocolo, Liesbeth Vossaert, et al.
Time to Treatment in Pediatric Patients With Repeated Episodes of Status Epilepticus, Jennifer V Gettings, Iván Sánchez Fernández, Anne Anderson, et al.
Volumetric Changes in Cerebellar Transverse Zones: Age and Sex Effects in Health and Neurological Disorders, Farshid Ghiyamihoor, Payam Paymani, Jarrad Perron, et al.
MultiSite Assembly of Gateway Induced Clones (MAGIC): A Flexible Cloning Toolbox for Use in Vertebrate Model Systems, William B Gillespie, Yuwen Zhang, Oscar E Ruiz, et al.
Distinguishing PEX2 and PEX16 Gene Variant Severity for Mild, Severe and Atypical Peroxisome Biogenesis Disorders, Vanessa A Gomez, Oguz Kanca, Sharayu V Jangam, et al.
Synaptic Alterations in Pyramidal Cells Following Genetic Manipulation of Neuronal Excitability in Monkey Prefrontal Cortex, Guillermo Gonzalez-Burgos, Takeaki Miyamae, Yosuke Nishihata, et al.
Blue-Shifted Ancyromonad Channelrhodopsins for Multiplex Optogenetics, Elena G Govorunova, Oleg A Sineshchekov, Hai Li, et al.
Diverse Ancestral Representation Improves Genetic Intolerance Metrics, Alexander L Han, Chloe F Sands, Dorota Matelska, et al.
Characterizing Features Affecting Local Ancestry Inference Performance in Admixed Populations, Jessica Honorato-Mauer, Nirav N Shah, Adam X Maihofer, et al.
Current Controversies in Prenatal Diagnosis 2: Conventional Postmortem Examination Remains the Gold Standard for the Anatomical Examination of Fetal Loss, J Ciaran Hutchinson, Lorraine Potocki, and Ignatia B Van den Veyver
Resolving SLC6A1 Variable Expressivity With Deep Clinical Phenotyping and Drosophila Models, Kristy L Jay, Nikhita Gogate, Paige I Hall, et al.
Breaking the Synaptic Vesicle Cycle: Mechanistic Insights into Presynaptic Dysfunctions in Epilepsy, Kevin Jiang, Lu-Tang Yang, and Mingshan Xue
Molecular Logic for Cellular Specializations That Initiate the Auditory Parallel Processing Pathways, Junzhan Jing, Ming Hu, Tenzin Ngodup, et al.
Protocol for Unlocking Alternative Polyadenylation Insights From Bulk RNA-Seq Data With PolyAMiner-Bulk, Venkata Jonnakuti, Sriya Jonnakuti, and Hari Krishna Yalamanchili
Multi-Epitope Immunocapture of Huntingtin Reveals Striatum-Selective Molecular Signatures, Joshua L Justice, Todd M Greco, Josiah E Hutton, et al.
The Small GTPase Rap1 in POMC Neurons Regulates Leptin Actions and Glucose Metabolism, Kentaro Kaneko, Weisheng Lu, Yong Xu, et al.
Pleiotropy and the Increasing Complexity of Parkinson's Disease Genetics, Jonggeol Kim and Joshua M Shulman
Alpha-Synuclein Phosphomimetic Y39E and S129D Knock-In Mice Show Cytosolic Alpha-Synuclein Localization without Developing Neurodegeneration or Motor Deficits, YoungDoo Kim, Bhupesh Vaidya, Joseph McInnes, et al.
Improved Allele Frequencies in Gnomad Through Local Ancestry Inference, Pragati Kore, Michael W Wilson, Grace Tiao, et al.
PICALM Alzheimer’s Risk Allele Causes Aberrant Lipid Droplets in Microglia, Alena Kozlova, Siwei Zhang, Ari Sudwarts, et al.
Cell Type-Specific Purifying Selection of Synonymous Mitochondrial DNA Variation, Caleb A Lareau, Patrick Maschmeyer, Yajie Yin, et al.
An Open-Label Study Evaluating the Safety and Efficacy of AMO-01 for the Treatment of Seizures in Phelan-McDermid Syndrome, Tess Levy, J Lloyd Holder, Joseph P Horrigan, et al.
A Protective Role of Src-1 Against Aging Associated Cognitive Decline, Hesong Liu, Yongjie Yang, Jonathan C Bean, et al.
Prolonged Exposure to Food Odors Suppresses Feeding via an Olfactory Bulb-to-Hypothalamus Circuit, Yao Liu, Hailan Liu, Huey-Xian Kelly Wong, et al.
Multi-Omics Delineate Growth Factor Network Underlying Exercise Effects in an Alzheimer’s Mouse Model, Xin Li, Chaozhong Liu, Wenbo Li, et al.