Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2025
Advancements in Prenatal Genetic Screening and Testing: Emerging Technologies and Evolving Applications, Mona M Makhamreh, Mei Ling Chong, and Ignatia B Van den Veyver
Heterozygous Variants in PLCG1 Affect Hearing, Vision, Cardiac, and Immune Function, Mengqi Ma, Yiming Zheng, Mingxi Deng, et al.
Common Aav Gene Therapy Vectors Show Nonselective Transduction of Ex Vivo Human Brain Tissue, J P McGinnis, Joshua Ortiz-Guzman, Maria Camila Guevara, et al.
Functional Assays in Drosophila Facilitate Classification of Variants of Uncertain Significance Associated With Rare Diseases, Jung-Wan Mok, Shelley B Gibson, Haley A Dostalik, et al.
C-Terminal Frameshift Variants in Gpkow Are Associated With a Multisystemic X-Linked Disorder, Jung-Wan Mok, Laura Mackay, Maria Blazo, et al.
Longitudinal Multi-Omics in Alpha-Synuclein Drosophila Model Discriminates Disease- From Age-Associated Pathologies in Parkinson’s Disease, Justin Moore, Timothy Wu, Justin Dhindsa, et al.
Adaptive Filters at the First Olfactory Synapse, Elizabeth H Moss and Benjamin R Arenkiel
Survey and Improvement Strategies for Gene Prioritization With Large Language Models, Matthew B Neeley, Guantong Qi, Guanchu Wang, et al.
Thalamic Deep Brain Stimulation Improves Movement in a Cerebellar Model of Lesion-Based Status Dystonicus, Megan X Nguyen, Amanda M Brown, Tao Lin, et al.
A Targeted Gene Expression Biomarker Predicts Clinic Low-Risk Meningioma Recurrence, Minh P Nguyen, Ramin A Morshed, Mark W Youngblood, et al.
Glucose Uptake in Pigment Glia Suppresses Tau-Induced Inflammation and Photoreceptor Degeneration, Mikiko Oka, Sho Nakajima, Emiko Suzuki, et al.
The Impact of Genetic Ancestry on Survival Outcomes in Pediatric Rhabdomyosarcoma: A Report From the Children’s Oncology Group, Ekene A Onwuka, Christina L Magyar, Bailey A Martin-Giacalone, et al.
NF2 Loss-of-Function and Hypoxia Drive Radiation Resistance in Grade 2 Meningiomas, Bhuvic Patel, Sangami Pugazenthi, Collin W English, et al.
Comprehensive Assessment Reveals Numerous Clinical and Neurophysiological Differences Between MECP2-Allelic Disorders, Davut Pehlivan, Chengjun Huang, Holly K Harris, et al.
Cerebellar Dysfunction in a Mouse Model of Childhood-Onset Manganese-Induced Dystonia Parkinsonism, Alexander N Rodichkin, Amanda M Brown, Pavani Devabathini, et al.
Investigation of Dynamic Regulation of TFEB Nuclear Shuttling by Microfluidics and Quantitative Modelling, Iacopo Ruolo, Sara Napolitano, Lorena Postiglione, et al.
Metabolomic Profiling Reveals Brain Lipid Alterations in PEX7-Deficient Models of Rhizomelic Chondrodysplasia Punctata, Riya Sankhe, Meredith I Williams, Wedad Fallatah, et al.
Folliculin Deletion in the Mouse Kidney Results in Cystogenesis of the Loops of Henle via Aberrant TFEB Activation, Ola Shalaby, Tomoko Ohmori, Koichiro Miike, et al.
Functional Regulation of Macrophages by Ces1d-Mediated Lipid Signaling in Immunometabolism, Long J Shao, Fathima Elizondo, Feng Gao, et al.
Loss of the Maternal Effect Gene NLRP2 Impairs Embryonic and Extra-Embryonic Development, Revealing a Novel Genetic Cause of Congenital Anomalies†, Momal Sharif, Zahra Anvar, Imen Chakchouk, et al.
The Causal Pivot: A Structural Approach to Genetic Heterogeneity and Variant Discovery in Complex Diseases, Chad A Shaw, C J Williams, Taotao Tan, et al.
Coenzyme Q Headgroup Intermediates Can Ameliorate a Mitochondrial Encephalopathy, Guangbin Shi, Claire Miller, Sota Kuno, et al.
MeCP2 Interacts With the Super Elongation Complex To Regulate Transcription, Jun Young Sonn, Wonho Kim, Marta Iwanaszko, et al.
Haploinsufficiency of ITSN1 Is Associated With a Substantial Increased Risk of Parkinson’s Disease, Thomas P Spargo, Chloe F Sands, Isabella R Juan, et al.
Glutamatergic Lateral Habenula Neurons Modulate Consolidation of Associative Memories, Snigdha Srivastava, I-Ching Wang, Mikhail Y Kochukov, et al.