Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2024
TFEB Controls Syncytiotrophoblast Formation and Hormone Production in Placenta, Marcella Cesana, Gennaro Tufano, Francesco Panariello, et al.
A GREB1-Steroid Receptor Feedforward Mechanism Governs Differential GREB1 Action in Endometrial Function and Endometriosis, Sangappa B Chadchan, Pooja Popli, Zian Liao, et al.
The Impact of the Turkish Population Variome on the Genomic Architecture of Rare Disease Traits, Zeynep Coban-Akdemir, Xiaofei Song, Francisco C Ceballos, et al.
Exome Sequencing Implicates Ancestry-Related Mendelian Variation at SYNE1 in Childhood-Onset Essential Hypertension, Ian Copeland, Edmond Wonkam-Tingang, Monesha Gupta-Malhotra, et al.
Strategic Stabilization of Arousal Boosts Sustained Attention, Jan Willem de Gee, Zakir Mridha, Marisa Hudson, et al.
Pushing the Boundaries of Rare Disease Diagnostics With the Help of the First Undiagnosed Hackathon, Angelica Maria Delgado-Vega, Helene Cederroth, Fulya Taylan, et al.
Loss of the Endoplasmic Reticulum Protein Tmem208 Affects Cell Polarity, Development, and Viability, Debdeep Dutta, Oguz Kanca, Rishi V Shridharan, et al.
Mapping SCA1 Regional Vulnerabilities Reveals Neural and Skeletal Muscle Contributions to Disease, Lisa Duvick, W Michael Southern, Kellie A Benzow, et al.
TMEM106B Coding Variant Is Protective and Deletion Detrimental in a Mouse Model of Tauopathy, George A Edwards, Caleb A Wood, Yang He, et al.
Using High-Frequency Oscillations From Brief Intraoperative Neural Recordings To Predict the Seizure Onset Zone, Behrang Fazli Besheli, Zhiyi Sha, Jay R Gavvala, et al.
Novel Hemizygous Single-Nucleotide Duplication in RPGR in a Patient With Retinal Dystrophy and Sensorineural Hearing Loss, Ryan J German, Blake Vuocolo, Liesbeth Vossaert, et al.
Circuit-Specific Deep Brain Stimulation Provides Insights into Movement Control., Aryn H Gittis and Roy V Sillitoe
Glial Lipid Droplets Resolve ROS During Sleep, Lindsey D Goodman, Matthew J Moulton, and Hugo J Bellen
Does Glial Lipid Dysregulation Alter Sleep in Alzheimer’s and Parkinson’s Disease?, Lindsey D Goodman, Matthew J Moulton, Guang Lin, et al.
Tau Is Required for Glial Lipid Droplet Formation and Resistance to Neuronal Oxidative Stress, Lindsey D Goodman, Isha Ralhan, Xin Li, et al.
PIEZO ion channels: force sensors of the interoceptive nervous system., Yasmeen M F Hamed, Britya Ghosh, and Kara L Marshall
Behavioral Screening Reveals a Conserved Residue in Y-Box RNA-Binding Protein Required for Associative Learning and Memory in C elegans, Ashley N Hayden, Katie L Brandel, Edward W Pietryk, et al.
Loss-of-Function in RBBP5 Results in a Syndromic Neurodevelopmental Disorder Associated With Microcephaly, Yue Huang, Kristy L Jay, Alden Yen-Wen Huang, et al.
PolyAMiner-Bulk Is a Deep Learning-Based Algorithm That Decodes Alternative Polyadenylation Dynamics from Bulk RNA-Seq Data, Venkata Soumith Jonnakuti, Eric J Wagner, Mirjana Maletić-Savatić, et al.
Metabolic Bioactivation of Antidepressants: Advance and Underlying Hepatotoxicity, Saleh M Khalil, Kevin R MacKenzie, Mirjana Maletic-Savatic, et al.
Maldi Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues, Saleh M Khalil, Xuan Qin, John M Hakenjos, et al.
MATR3 Pathogenic Variants Differentially Impair Its Cryptic Splicing Repression Function, Mashiat Khan, Xiao Xiao Lily Chen, Michelle Dias, et al.
USF2 and TFEB Compete in Regulating Lysosomal and Autophagy Genes, Jaebeom Kim, Young Suk Yu, Yehwa Choi, et al.
TYK2 Regulates Tau Levels, Phosphorylation and Aggregation in a Tauopathy Mouse Model, Jiyoen Kim, Bakhos Tadros, Yan Hong Liang, et al.
GABAergic/Glycinergic and Glutamatergic Neurons Mediate Distinct Neurodevelopmental Phenotypes of STXBP1 Encephalopathy, Joo Hyun Kim, Wu Chen, Eugene S Chao, et al.