Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2025
Protocol for Unlocking Alternative Polyadenylation Insights From Bulk RNA-Seq Data With PolyAMiner-Bulk, Venkata Jonnakuti, Sriya Jonnakuti, and Hari Krishna Yalamanchili
The Small GTPase Rap1 in POMC Neurons Regulates Leptin Actions and Glucose Metabolism, Kentaro Kaneko, Weisheng Lu, Yong Xu, et al.
Alpha-Synuclein Phosphomimetic Y39E and S129D Knock-In Mice Show Cytosolic Alpha-Synuclein Localization without Developing Neurodegeneration or Motor Deficits, YoungDoo Kim, Bhupesh Vaidya, Joseph McInnes, et al.
Cell Type-Specific Purifying Selection of Synonymous Mitochondrial DNA Variation, Caleb A Lareau, Patrick Maschmeyer, Yajie Yin, et al.
A Protective Role of Src-1 Against Aging Associated Cognitive Decline, Hesong Liu, Yongjie Yang, Jonathan C Bean, et al.
Prolonged Exposure to Food Odors Suppresses Feeding via an Olfactory Bulb-to-Hypothalamus Circuit, Yao Liu, Hailan Liu, Huey-Xian Kelly Wong, et al.
Multi-Omics Delineate Growth Factor Network Underlying Exercise Effects in an Alzheimer’s Mouse Model, Xin Li, Chaozhong Liu, Wenbo Li, et al.
Heterozygous Variants in PLCG1 Affect Hearing, Vision, Cardiac, and Immune Function, Mengqi Ma, Yiming Zheng, Mingxi Deng, et al.
Common Aav Gene Therapy Vectors Show Nonselective Transduction of Ex Vivo Human Brain Tissue, J P McGinnis, Joshua Ortiz-Guzman, Maria Camila Guevara, et al.
C-Terminal Frameshift Variants in Gpkow Are Associated With a Multisystemic X-Linked Disorder, Jung-Wan Mok, Laura Mackay, Maria Blazo, et al.
Longitudinal Multi-Omics in Alpha-Synuclein Drosophila Model Discriminates Disease- From Age-Associated Pathologies in Parkinson’s Disease, Justin Moore, Timothy Wu, Justin Dhindsa, et al.
Adaptive Filters at the First Olfactory Synapse, Elizabeth H Moss and Benjamin R Arenkiel
Survey and Improvement Strategies for Gene Prioritization With Large Language Models, Matthew B Neeley, Guantong Qi, Guanchu Wang, et al.
A Targeted Gene Expression Biomarker Predicts Clinic Low-Risk Meningioma Recurrence, Minh P Nguyen, Ramin A Morshed, Mark W Youngblood, et al.
Glucose Uptake in Pigment Glia Suppresses Tau-Induced Inflammation and Photoreceptor Degeneration, Mikiko Oka, Sho Nakajima, Emiko Suzuki, et al.
NF2 Loss-of-Function and Hypoxia Drive Radiation Resistance in Grade 2 Meningiomas, Bhuvic Patel, Sangami Pugazenthi, Collin W English, et al.
Comprehensive Assessment Reveals Numerous Clinical and Neurophysiological Differences Between MECP2-Allelic Disorders, Davut Pehlivan, Chengjun Huang, Holly K Harris, et al.
Cerebellar Dysfunction in a Mouse Model of Childhood-Onset Manganese-Induced Dystonia Parkinsonism, Alexander N Rodichkin, Amanda M Brown, Pavani Devabathini, et al.
Investigation of Dynamic Regulation of TFEB Nuclear Shuttling by Microfluidics and Quantitative Modelling, Iacopo Ruolo, Sara Napolitano, Lorena Postiglione, et al.
Folliculin Deletion in the Mouse Kidney Results in Cystogenesis of the Loops of Henle via Aberrant TFEB Activation, Ola Shalaby, Tomoko Ohmori, Koichiro Miike, et al.
Functional Regulation of Macrophages by Ces1d-Mediated Lipid Signaling in Immunometabolism, Long J Shao, Fathima Elizondo, Feng Gao, et al.
The Causal Pivot: A Structural Approach to Genetic Heterogeneity and Variant Discovery in Complex Diseases, Chad A Shaw, C J Williams, Taotao Tan, et al.
Coenzyme Q Headgroup Intermediates Can Ameliorate a Mitochondrial Encephalopathy, Guangbin Shi, Claire Miller, Sota Kuno, et al.
Haploinsufficiency of ITSN1 Is Associated With a Substantial Increased Risk of Parkinson’s Disease, Thomas P Spargo, Chloe F Sands, Isabella R Juan, et al.
Glutamatergic Lateral Habenula Neurons Modulate Consolidation of Associative Memories, Snigdha Srivastava, I-Ching Wang, Mikhail Y Kochukov, et al.