Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2024
Glial Lipid Droplets Resolve ROS During Sleep, Lindsey D Goodman, Matthew J Moulton, and Hugo J Bellen
Does Glial Lipid Dysregulation Alter Sleep in Alzheimer’s and Parkinson’s Disease?, Lindsey D Goodman, Matthew J Moulton, Guang Lin, et al.
Tau Is Required for Glial Lipid Droplet Formation and Resistance to Neuronal Oxidative Stress, Lindsey D Goodman, Isha Ralhan, Xin Li, et al.
PIEZO Ion Channels: Force Sensors of the Interoceptive Nervous System, Yasmeen M F Hamed, Britya Ghosh, and Kara L Marshall
Behavioral Screening Reveals a Conserved Residue in Y-Box RNA-Binding Protein Required for Associative Learning and Memory in C elegans, Ashley N Hayden, Katie L Brandel, Edward W Pietryk, et al.
Loss-of-Function in RBBP5 Results in a Syndromic Neurodevelopmental Disorder Associated With Microcephaly, Yue Huang, Kristy L Jay, Alden Yen-Wen Huang, et al.
PolyAMiner-Bulk Is a Deep Learning-Based Algorithm That Decodes Alternative Polyadenylation Dynamics from Bulk RNA-Seq Data, Venkata Soumith Jonnakuti, Eric J Wagner, Mirjana Maletić-Savatić, et al.
Metabolic Bioactivation of Antidepressants: Advance and Underlying Hepatotoxicity, Saleh M Khalil, Kevin R MacKenzie, Mirjana Maletic-Savatic, et al.
Maldi Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues, Saleh M Khalil, Xuan Qin, John M Hakenjos, et al.
MATR3 Pathogenic Variants Differentially Impair Its Cryptic Splicing Repression Function, Mashiat Khan, Xiao Xiao Lily Chen, Michelle Dias, et al.
USF2 and TFEB Compete in Regulating Lysosomal and Autophagy Genes, Jaebeom Kim, Young Suk Yu, Yehwa Choi, et al.
TYK2 Regulates Tau Levels, Phosphorylation and Aggregation in a Tauopathy Mouse Model, Jiyoen Kim, Bakhos Tadros, Yan Hong Liang, et al.
GABAergic/Glycinergic and Glutamatergic Neurons Mediate Distinct Neurodevelopmental Phenotypes of STXBP1 Encephalopathy, Joo Hyun Kim, Wu Chen, Eugene S Chao, et al.
Cerebellar Functions Beyond Movement and Learning, Linda H Kim, Detlef H Heck, and Roy V Sillitoe
Olfactory Deficit and Gastrointestinal Dysfunction Precede Motor Abnormalities in Alpha-Synuclein G51D Knock-In Mice, YoungDoo Kim, Joseph McInnes, Jiyoen Kim, et al.
Diagnostic Utility of DNA Methylation Analysis in Genetically Unsolved Pediatric Epilepsies and CHD2 Episignature Refinement, Christy W LaFlamme, Cassandra Rastin, Soham Sengupta, et al.
RNA Splicing as a Biomarker and Phenotypic Driver of Meningioma DNA-Methylation Groups, Nathan K Leclair, Abrar Choudury, William C Chen, et al.
Clinical, Genetic, and Cognitive Correlates of Seizure Occurrences in Phelan-McDermid Syndrome, Tess Levy, Jacob Gluckman, Paige M Siper, et al.
MetaboLINK Is a Novel Algorithm for Unveiling Cell-Specific Metabolic Pathways in Longitudinal Datasets, Jared Lichtarge, Gerarda Cappuccio, Soumya Pati, et al.
A Zika Virus Protein Expression Screen in Drosophila To Investigate Targeted Host Pathways During Development, Nichole Link, J Michael Harnish, Brooke Hull, et al.
The Clinical Utility and Diagnostic Implementation of Human Subject Cell Transdifferentiation Followed by RNA Sequencing, Shenglan Li, Sen Zhao, Jefferson C Sinson, et al.
Quantification and Visualization of Cis-Regulatory Dynamics in Single-Cell Multi-Omics Data With TREASMO, Chaozhong Liu, Linhua Wang, and Zhandong Liu
Distinct Basal Forebrain-Originated Neural Circuits Promote Homoeostatic Feeding and Suppress Hedonic Feeding in Male Mice, Hailan Liu, Jonathan C Bean, Yongxiang Li, et al.
Therapeutic Strategies Against Metabolic Imbalance in a Male Mouse Model With 5-HT2CR Loss-of-Function, Hailan Liu, Zhaoxun Liu, HueyXian Kelly Wong, et al.
Neural Circuits Expressing the Serotonin 2C Receptor Regulate Memory in Mice and Humans, Hesong Liu, Yang He, Hailan Liu, et al.