The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2025
The Impact of Genetic Ancestry on Survival Outcomes in Pediatric Rhabdomyosarcoma: A Report From the Children’s Oncology Group, Ekene A Onwuka, Christina L Magyar, Bailey A Martin-Giacalone, et al.
Sensory-selective Peripheral and Neuraxial Nerve Blockade with 2',6'-Pipecoloxylidide, Claire A Ostertag-Hill, Shuanglong Chen, Tianrui Xue, et al.
Distinct Systemic Impacts of Aβ42 and Tau Revealed by Whole-Organism snRNA-Seq, Ye-Jin Park, Tzu-Chiao Lu, Tyler Jackson, et al.
NF2 Loss-of-Function and Hypoxia Drive Radiation Resistance in Grade 2 Meningiomas, Bhuvic Patel, Sangami Pugazenthi, Collin W English, et al.
Comprehensive Assessment Reveals Numerous Clinical and Neurophysiological Differences Between MECP2-Allelic Disorders, Davut Pehlivan, Chengjun Huang, Holly K Harris, et al.
The Medial Olivocochlear Efferent Pathway Potentiates Cochlear Amplification in Response to Hearing Loss, Patricia M Quiñones, Michelle Pei, Hemant Srivastava, et al.
Cerebellar Dysfunction in a Mouse Model of Childhood-Onset Manganese-Induced Dystonia Parkinsonism, Alexander N Rodichkin, Amanda M Brown, Pavani Devabathini, et al.
Investigation of Dynamic Regulation of TFEB Nuclear Shuttling by Microfluidics and Quantitative Modelling, Iacopo Ruolo, Sara Napolitano, Lorena Postiglione, et al.
Metabolomic Profiling Reveals Brain Lipid Alterations in PEX7-Deficient Models of Rhizomelic Chondrodysplasia Punctata, Riya Sankhe, Meredith I Williams, Wedad Fallatah, et al.
Differential Antibody Response to Ebv Proteome Following EBVST Immunotherapy in EBV-Associated Lymphomas, Yomani D Sarathkumara, Nathan W Van Bibber, Zhiwei Liu, et al.
Folliculin Deletion in the Mouse Kidney Results in Cystogenesis of the Loops of Henle via Aberrant TFEB Activation, Ola Shalaby, Tomoko Ohmori, Koichiro Miike, et al.
Functional Regulation of Macrophages by Ces1d-Mediated Lipid Signaling in Immunometabolism, Long J Shao, Fathima Elizondo, Feng Gao, et al.
Loss of the Maternal Effect Gene NLRP2 Impairs Embryonic and Extra-Embryonic Development, Revealing a Novel Genetic Cause of Congenital Anomalies†, Momal Sharif, Zahra Anvar, Imen Chakchouk, et al.
The Causal Pivot: A Structural Approach to Genetic Heterogeneity and Variant Discovery in Complex Diseases, Chad A Shaw, C J Williams, Taotao Tan, et al.
Coenzyme Q Headgroup Intermediates Can Ameliorate a Mitochondrial Encephalopathy, Guangbin Shi, Claire Miller, Sota Kuno, et al.
MeCP2 Interacts With the Super Elongation Complex To Regulate Transcription, Jun Young Sonn, Wonho Kim, Marta Iwanaszko, et al.
Haploinsufficiency of ITSN1 Is Associated With a Substantial Increased Risk of Parkinson’s Disease, Thomas P Spargo, Chloe F Sands, Isabella R Juan, et al.
Glutamatergic Lateral Habenula Neurons Modulate Consolidation of Associative Memories, Snigdha Srivastava, I-Ching Wang, Mikhail Y Kochukov, et al.
Computational and Functional Prioritization Identifies Genes That Rescue Behavior and Reduce Tau Protein in Fly and Human Cell Models of Alzheimer Disease, Morgan C Stephens, Jiayang Li, Megan Mair, et al.
New Insights Into Epileptic Spasm Generation and Treatment From the TTX Animal Model, John W Swann, Carlos J Ballester-Rosado, and Chih-Hong Lee
The Biological Intersection Between Chemotherapy-Related Cognitive Impairment and Alzheimer Disease, Matthew Torre, Camila A Zanella, and Mel B Feany
Vestibular Neurons Link Motion Sickness, Behavioural Thermoregulation and Metabolic Balance in Mice, Longlong Tu, Xing Fang, Yongjie Yang, et al.
Biliverdin Reductase A Is a Major Determinant of Protective NRF2 Signaling, Chirag Vasavda, Ruchita Kothari, Navneet Ammal Kaidery, et al.
From Bladder to Brain: How You Know When It’s Time To Go, Anne M J Verstegen and Kara L Marshall
Drosophila Models Uncover Substrate Channeling Effects on Phospholipids and Sphingolipids in Peroxisomal Biogenesis Disorders, Michael F Wangler, Yu-Hsin Chao, Mary Roth, et al.