Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2024
Age-Related TFEB Downregulation in Proximal Tubules Causes Systemic Metabolic Disorders and Occasional Apolipoprotein A4-Related Amyloidosis, Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, et al.
Role of NF2 Mutation in the Development of Eleven Different Cancers, Shervin Hosseingholi Nouri, Vijay Nitturi, Elizabeth Ledbetter, et al.
Cholinergic Basal Forebrain Connectivity to the Basolateral Amygdala Modulates Food Intake, Joshua Ortiz-Guzman, Jessica L Swanson, Evelyne K Tantry, et al.
De Novo Variants in FRYL Are Associated With Developmental Delay, Intellectual Disability, and Dysmorphic Features, Xueyang Pan, Alice M Tao, Shenzhao Lu, et al.
A Syndromic Neurodevelopmental Disorder Caused by Rare Variants in PPFIA3, Maimuna S Paul, Sydney L Michener, Hongling Pan, et al.
Alzheimer’s Disease Risk Gene CD2AP Is a Dose-Sensitive Determinant of Synaptic Structure and Plasticity, Matea Pavešković, Ruth B De-Paula, Shamsideen A Ojelade, et al.
Structural Variant Allelic Heterogeneity in MECP2 Duplication Syndrome Provides Insight Into Clinical Severity and Variability of Disease Expression, Davut Pehlivan, Jesse D Bengtsson, Sameer S Bajikar, et al.
Multiomic and Clinical Analysis of Multiply Recurrent Meningiomas Reveals Risk Factors, Underlying Biology, and Insights Into Evolution, Sangami Pugazenthi, Bhuvic Patel, Collin W English, et al.
Identification of an Early Subset of Cerebellar Nuclei Neurons in Mice, Maryam Rahimi-Balaei, Shayan Amiri, Thomas Lamonerie, et al.
Case Report: Contralateral Progression of a Vestibular Schwannoma After Resection in a Patient with Neurofibromatosis Type 2, Ihika Rampalli, Collin William English, Tyler Lazaro, et al.
Purkinje Cell Dysfunction Causes Disrupted Sleep in Ataxic Mice, Luis E Salazar Leon, Amanda M Brown, Heet Kaku, et al.
Cerebellar Deep Brain Stimulation as a Dual-Function Therapeutic for Restoring Movement and Sleep in Dystonic Mice, Luis E Salazar Leon, Linda H Kim, and Roy V Sillitoe
Ragopathies and the Rising Influence of RagGTPases on Human Diseases, Irene Sambri, Marco Ferniani, and Andrea Ballabio
Rigor and Reproducibility in Human Brain Organoid Research: Where We Are and Where We Need to Go, Soraya O Sandoval, Gerarda Cappuccio, Karina Kruth, et al.
Plasmodium berghei Liver Stage Parasites Exploit Host GABARAP Proteins for TFEB Activation, Jacqueline Schmuckli-Maurer, Annina F Bindschedler, Rahel Wacker, et al.
Variants in Zfx Are Associated With an X-Linked Neurodevelopmental Disorder With Recurrent Facial Gestalt\, James L Shepherdson, Katie Hutchison, Dilan Wellalage Don, et al.
Research Participants' Perspectives on Precision Diagnostics for Alzheimer's Disease, Hadley Stevens Smith, Jill O Robinson, Ariel Levchenko, et al.
Comparative Exploration of Mammalian Deafness Gene Homologues in the Drosophila Auditory Organ Shows Genetic Correlation Between Insect and Vertebrate Hearing, Daniel C Sutton, Jonathan C Andrews, Dylan M Dolezal, et al.
Histone Proteoform Analysis Reveals Epigenetic Changes in Adult Mouse Brown Adipose Tissue in Response to Cold Stress, Bethany C Taylor, Loic H Steinthal, Michelle Dias, et al.
Longitudinal Single-Cell Transcriptional Dynamics Throughout Neurodegeneration in SCA1, Leon Tejwani, Neal G Ravindra, Changwoo Lee, et al.
The Impact of Clinical Genome Sequencing in a Global Population With Suspected Rare Genetic Disease, Erin Thorpe, Taylor Williams, Chad Shaw, et al.
RRAGD-Associated Autosomal Dominant Kidney Hypomagnesemia with Cardiomyopathy: A Review on the Clinical Manifestations and Therapeutic Options, Francesco Trepiccione, Irene Sambri, Barbara Ruggiero, et al.
Cerebellar Nuclei Cells Produce Distinct Pathogenic Spike Signatures in Mouse Models of Ataxia, Dystonia, and Tremor, Meike E van der Heijden, Amanda M Brown, Dominic J Kizek, et al.
Improving Access to Exome Sequencing in a Medically Underserved Population Through the Texome Project, Blake Vuocolo, Ryan J German, Seema R Lalani, et al.
Aging Fly Cell Atlas Identifies Exhaustive Aging Features at Cellular Resolution, Kenneth A Wilson, Sudipta Bar, Eric B Dammer, et al.