The HCOA was formed in 1988 by the generosity of the late ">Roy M. and Phyllis Gough Huffington, Houston philanthropists who foresaw the need for an academic entity devoted to studying aging, providing care for older people, and teaching future health professionals and researchers about geriatrics and gerontology.
The Roy M. and Phyllis Gough Huffington Center on Aging spearheads breakthrough research and is committed to translating basic research discoveries into applications that promote healthy aging and combat age-associated disorders. The faculty, along with their research staff and trainees, utilize diverse model systems and multidisciplinary approaches to address questions that are of crucial importance to the biology, pathophysiology and diseases of aging. The major research topics include lifespan and health span studies, aging of the endocrine, vasculature, and central nervous systems, cancer, and neurodegenerative diseases, in particular Alzheimer’s disease..
Submissions from 2023
Cell-Type-Specific Aging Clocks To Quantify Aging and Rejuvenation in Neurogenic Regions of the Brain, Matthew T Buckley, Eric D Sun, Benson M George, et al.
Cellular Senescence and Frailty in Transplantation, Elizabeth C Lorenz, LaTonya J Hickson, Pascale Khairallah, et al.
Circadian Clock and Temporal Meal Pattern, Xin Li and Zheng Sun
Circulating Metabolites May Illustrate Relationship of Alcohol Consumption With Cardiovascular Disease, Yi Li, Mengyao Wang, Xue Liu, et al.
Clinical Performance Characteristics for Bordered Foam Dressings in the Treatment of Complex Wounds: An International Wound Dressing Technology Expert Panel Review, Nick Santamaria, Kevin Woo, Dimitri Beeckman, et al.
Complement C3aR Depletion Reverses HIF-1α-Induced Metabolic Impairment and Enhances Microglial Response to Aβ Pathology, Manasee Gedam, Michele M Comerota, Nicholas E Propson, et al.
COVID-19 and Pregnancy: Clinical Outcomes; Mechanisms, and Vaccine Efficacy, Deepak Kumar, Sonam Verma, and Indira U Mysorekar
Daily Posture Behavior Patterns Derived From Multitime-Scale Topic Models Using Wearable Triaxial Acceleration for Assessment of Concern About Falling, Changhong Wang, Yu Wang, Haitao Zhao, et al.
Diabetes Technology Meeting 2022, Jingtong Huang, Andrea M Yeung, Ashley Y DuBord, et al.
Discovery of Associative Patterns Between Workplace Sound Level and Physiological Wellbeing Using Wearable Devices and Empirical Bayes Modeling, Karthik Srinivasan, Faiz Currim, Casey M Lindberg, et al.
DNMT3A-Coordinated Splicing Governs the Stem State Switch Towards Differentiation in Embryonic and Haematopoietic Stem Cells, Raghav Ramabadran, Jarey H Wang, Jaime M Reyes, et al.
Dopamine Signaling From Ganglion Cells Directs Layer-Specific Angiogenesis in the Retina, Justine H Liang, Viktor Akhanov, Anthony Ho, et al.
Dual-Task Upper Extremity Motor Performance Measured by Video Processing as Cognitive-Motor Markers for Older Adults, Changhong Wang, Mohsen Zahiri, Ashkan Vaziri, et al.
Effects of Aging on Urinary Tract Epithelial Homeostasis and Immunity, Marianne M Ligon, Chetanchandra S Joshi, Bisiayo E Fashemi, et al.
Efficient Cancer Modeling Through Crispr-Cas9/Hdr-Based Somatic Precision Gene Editing In Mice, Wen Bu, Chad J Creighton, Kelsey S Heavener, et al.
Electrical Stimulation To Regain Lower Extremity Muscle Perfusion and Endurance in Patients With Post-Acute Sequelae of SARS CoV-2: A Randomized Controlled Trial, Alejandro Zulbaran-Rojas, Myeounggon Lee, Rasha O Bara, et al.
Emergent Dynamics of Adult Stem Cell Lineages From Single Nucleus and Single Cell RNA-Seq Of Drosophila testes, Amelie A Raz, Gabriela S Vida, Sarah R Stern, et al.
Engineered PROTAC-CID Systems for Mammalian Inducible Gene Regulation, Dacheng Ma, Qichen Yuan, Fei Peng, et al.
Evaluation of Apparent Diffusion Coefficient Repeatability and Reproducibility for Preclinical MRIs Using Standardized Procedures and a Diffusion-Weighted Imaging Phantom, Dariya Malyarenko, Ghoncheh Amouzandeh, Stephen Pickup, et al.
Exercise Reprograms the Inflammatory Landscape of Multiple Stem Cell Compartments During Mammalian Aging, Ling Liu, Soochi Kim, Matthew T Buckley, et al.
Functional Screening of Lysosomal Storage Disorder Genes Identifies Modifiers of Alpha-Synuclein Neurotoxicity, Meigen Yu, Hui Ye, Ruth B De-Paula, et al.
Game-Based Intradialytic Non-Weight-Bearing Exercise Training on Gait Speed and Balance in Older Adults With Diabetes: A Single-Blind Randomized Controlled Trial, M G Finco, Bijan Najafi, He Zhou, et al.
Genetics and Pathogenesis of Parkinson's Syndrome, Hui Ye, Laurie A Robak, Meigen Yu, et al.
Hematopoietic Stem and Progenitor Cells Confer Cross-Protective Trained Immunity in Mouse Models, Bailee N Kain, Brandon T Tran, Pamela N Luna, et al.
Home-Based Electrical Stimulation to Accelerate Wound Healing-A Double-Blinded Randomized Control Trial, Alejandro Zulbaran-Rojas, Catherine Park, Nesreen El-Refaei, et al.