The HCOA was formed in 1988 by the generosity of the late ">Roy M. and Phyllis Gough Huffington, Houston philanthropists who foresaw the need for an academic entity devoted to studying aging, providing care for older people, and teaching future health professionals and researchers about geriatrics and gerontology.
The Roy M. and Phyllis Gough Huffington Center on Aging spearheads breakthrough research and is committed to translating basic research discoveries into applications that promote healthy aging and combat age-associated disorders. The faculty, along with their research staff and trainees, utilize diverse model systems and multidisciplinary approaches to address questions that are of crucial importance to the biology, pathophysiology and diseases of aging. The major research topics include lifespan and health span studies, aging of the endocrine, vasculature, and central nervous systems, cancer, and neurodegenerative diseases, in particular Alzheimer’s disease..
Submissions from 2022
Pilot Study for Correlation of Heart Rate Variability and Dopamine Transporter Brain Imaging in Patients with Parkinsonian Syndrome, Devdutta S Warhadpande, Jiayan Huo, William A Libling, et al.
Pleiomorphism Plurihormonal Pit-1-Positive Macroadenoma With Central Hyperthyroidism: A Rare Case Report and Literature Review, Guiliang Peng, Chuanhong Guo, Yangfan Lv, et al.
Post-Developmental Plasticity of the Primary Rod Pathway Allows Restoration of Visually Guided Behaviors, Yan Cao, Diego Fajardo, Debbie Guerrero-Given, et al.
PPM1D in Solid and Hematologic Malignancies: Friend and Foe?, Linda Zhang, Joanne I Hsu, and Margaret A Goodell
Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 (HDAC3) Stabilization and Chromatin Condensation, Laure Maneix, Polina Iakova, Shannon E Moree, et al.
REV-ERB is Essential in Cardiac Fibroblasts Homeostasis, Xiaokang Luo, Shiyang Song, Lei Qi, et al.
RNA Binding Protein RBM46 Regulates Mitotic-to-Meiotic Transition in Spermatogenesis, Baomei Qian, Yang Li, Ruoyu Yan, et al.
RSPO2 and RANKL Signal Through LGR4 To Regulate Osteoclastic Premetastatic Niche Formation and Bone Metastasis, Zhiying Yue, Xin Niu, Zengjin Yuan, et al.
Safety and Efficacy of Electrical Stimulation for Lower-Extremity Muscle Weakness in Intensive Care Unit 2019 Novel Coronavirus Patients: A Phase I Double-Blinded Randomized Controlled Trial, Alejandro Zulbaran-Rojas, Ramkinker Mishra, Naima Rodriguez, et al.
Smart-Home Concept for Remote Monitoring of Instrumental Activities of Daily Living (IADL) in Older Adults with Cognitive Impairment: A Proof of Concept and Feasibility Study, Myeounggon Lee, Ram Kinker Mishra, Anmol Momin, et al.
SR9009 Improves Heart Function After Pressure Overload Independent of Cardiac REV-ERB, Hui Li, Shiyang Song, Chih-Liang Tien, et al.
STAT6 Blockade Abrogates Aspergillus-Induced Eosinophilic Chronic Rhinosinusitis and Asthma, A Model of Unified Airway Disease, Meng Lin, Amy T Ku, Jie Dong, et al.
Systemic Delivery of Divalent Europium from Ligand Screening with Implications to Direct Imaging of Hypoxia, Md Mamunur Rashid, Brooke A Corbin, Pavan Jella, et al.
Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer, Adelaide Young, Wen Bu, Weiyu Jiang, et al.
Tele-Medicine Based and Self-Administered Interactive Exercise Program (Tele-Exergame) to Improve Cognition in Older Adults with Mild Cognitive Impairment or Dementia: A Feasibility, Acceptability, and Proof-of-Concept Study, Catherine Park, Ram Kinker Mishra, Michele K York, et al.
The Rheumatoid Arthritis Drug Auranofin Lowers Leptin Levels and Exerts Antidiabetic Effects in Obese Mice, Aaron R Cox, Peter M Masschelin, Pradip K Saha, et al.
Using Wearable Sensors to Measure Goal Achievement in Older Veterans with Dementia, Jennifer Freytag, Ram Kinker Mishra, Richard L Street, et al.