Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2024
Experiences in Providing a Community Educational Resource for the All of Us Researcher Workbench, Deborah I Ritter, Jinyoung Byun, Jun Wang, et al.
Purkinje Cell Dysfunction Causes Disrupted Sleep in Ataxic Mice, Luis E Salazar Leon, Amanda M Brown, Heet Kaku, et al.
Cerebellar Deep Brain Stimulation as a Dual-Function Therapeutic for Restoring Movement and Sleep in Dystonic Mice, Luis E Salazar Leon, Linda H Kim, and Roy V Sillitoe
Ragopathies and the Rising Influence of RagGTPases on Human Diseases, Irene Sambri, Marco Ferniani, and Andrea Ballabio
Rigor and Reproducibility in Human Brain Organoid Research: Where We Are and Where We Need to Go, Soraya O Sandoval, Gerarda Cappuccio, Karina Kruth, et al.
Plasmodium berghei Liver Stage Parasites Exploit Host GABARAP Proteins for TFEB Activation, Jacqueline Schmuckli-Maurer, Annina F Bindschedler, Rahel Wacker, et al.
Variants in Zfx Are Associated With an X-Linked Neurodevelopmental Disorder With Recurrent Facial Gestalt\, James L Shepherdson, Katie Hutchison, Dilan Wellalage Don, et al.
Research Participants' Perspectives on Precision Diagnostics for Alzheimer's Disease, Hadley Stevens Smith, Jill O Robinson, Ariel Levchenko, et al.
Neurofeedback: New Territories and Neurocognitive Mechanisms of Endogenous Neuromodulation, James Sulzer, T Dorina Papageorgiou, Rainer Goebel, et al.
Comparative Exploration of Mammalian Deafness Gene Homologues in the Drosophila Auditory Organ Shows Genetic Correlation Between Insect and Vertebrate Hearing, Daniel C Sutton, Jonathan C Andrews, Dylan M Dolezal, et al.
Histone Proteoform Analysis Reveals Epigenetic Changes in Adult Mouse Brown Adipose Tissue in Response to Cold Stress, Bethany C Taylor, Loic H Steinthal, Michelle Dias, et al.
Longitudinal Single-Cell Transcriptional Dynamics Throughout Neurodegeneration in SCA1, Leon Tejwani, Neal G Ravindra, Changwoo Lee, et al.
The Impact of Clinical Genome Sequencing in a Global Population With Suspected Rare Genetic Disease, Erin Thorpe, Taylor Williams, Chad Shaw, et al.
RRAGD-Associated Autosomal Dominant Kidney Hypomagnesemia with Cardiomyopathy: A Review on the Clinical Manifestations and Therapeutic Options, Francesco Trepiccione, Irene Sambri, Barbara Ruggiero, et al.
Cerebellar Nuclei Cells Produce Distinct Pathogenic Spike Signatures in Mouse Models of Ataxia, Dystonia, and Tremor, Meike E van der Heijden, Amanda M Brown, Dominic J Kizek, et al.
Improving Access to Exome Sequencing in a Medically Underserved Population Through the Texome Project, Blake Vuocolo, Ryan J German, Seema R Lalani, et al.
Aging Fly Cell Atlas Identifies Exhaustive Aging Features at Cellular Resolution, Kenneth A Wilson, Sudipta Bar, Eric B Dammer, et al.
Chemogenetic Neuronal Silencing Decouples C-Jun Activation From Cell Death in the Temporal Cortex, Caleb A Wood, Preethi Somasundaram, Jacob M Dundee, et al.
Astrocytic Slc4a4 Regulates Blood-Brain Barrier Integrity in Healthy and Stroke Brains via a CCL2-CCR2 Pathway and No Dysregulation, Qi Ye, Juyeon Jo, Chih-Yen Wang, et al.
Impact of Prenatal Genomics on Clinical Genetics Practice, Roni Zemet and Ignatia B Van den Veyver
Submissions from 2023
Loss of Neuron Navigator 2 Impairs Brain and Cerebellar Development, Andrea Accogli, Shenzhao Lu, Ilaria Musante, et al.
De Novo Variants in MRTFB Have Gain-of-Function Activity in Drosophila and Are Associated With a Novel Neurodevelopmental Phenotype With Dysmorphic Features, Jonathan C Andrews, Jung-Wan Mok, Oguz Kanca, et al.
Loss of the Maternal Effect Gene Nlrp2 Alters the Transcriptome of Ovulated Mouse Oocytes and Impacts Expression of Histone Demethylase KDM1B, Zahra Anvar, Imen Chakchouk, Momal Sharif, et al.
MeCP2 Regulates Gdf11, a Dosage-Sensitive Gene Critical for Neurological Function, Sameer S Bajikar, Ashley G Anderson, Jian Zhou, et al.
The Cerebellum Contributes to Generalized Seizures by Altering Activity in the Ventral Posteromedial Nucleus, Jaclyn Beckinghausen, Joshua Ortiz-Guzman, Tao Lin, et al.