Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2023
The Fly Homolog of SUPT16H, a Gene Associated With Neurodevelopmental Disorders, Is Required in a Cell-Autonomous Fashion for Cell Survival, Mengqi Ma, Xi Zhang, Yiming Zheng, et al.
Prevalence of Pathogenic Germline Variants in Adult-Type Diffuse Glioma, Malcolm F McDonald, Lyndsey L Prather, Cassandra R Helfer, et al.
Cellular Composition and Circuit Organization of the Locus Coeruleus of Adult Mice, Andrew McKinney, Ming Hu, Amber Hoskins, et al.
Effects of Protein-Coding Variants on Blood Metabolite Measurements and Clinical Biomarkers in the UK Biobank, Abhishek Nag, Ryan S Dhindsa, Lawrence Middleton, et al.
TFEB-Mediated Lysosomal Exocytosis Alleviates High-Fat Diet-Induced Lipotoxicity in the Kidney, Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, et al.
Rare De Novo Gain-of-Function Missense Variants in DOT1L Are Associated With Developmental Delay and Congenital Anomalies, Zelha Nil, Ashish R Deshwar, Yan Huang, et al.
Allelic Strengths of Encephalopathy-Associated UBA5 Variants Correlate Between In Vivo and In Vitro Assays, Xueyang Pan, Albert N Alvarez, Mengqi Ma, et al.
Sphingolipids in Neurodegenerative Diseases, Xueyang Pan, Debdeep Dutta, Shenzhao Lu, et al.
TFEB and TFE3 Control Glucose Homeostasis by Regulating Insulin Gene Expression, Adrien Pasquier, Nunzia Pastore, Luca D'Orsi, et al.
Rare EIF4A2 Variants Are Associated With a Neurodevelopmental Disorder Characterized by Intellectual Disability, Hypotonia, and Epilepsy, Maimuna S Paul, Anna R Duncan, Casie A Genetti, et al.
Antagonistic Effect of Cyclin-Dependent Kinases and a Calcium-Dependent Phosphatase on Polyglutamine-Expanded Androgen Receptor Toxic Gain of Function, Diana Piol, Laura Tosatto, Emanuela Zuccaro, et al.
Dynamic Mapping of Proteome Trafficking Within and Between Living Cells by TransitID, Wei Qin, Joleen S Cheah, Charles Xu, et al.
Autolysosomal Exocytosis of Lipids Protect Neurons From Ferroptosis, Isha Ralhan, Jinlan Chang, Matthew J Moulton, et al.
The Voltage-Gated Sodium Channel in Drosophila, Para, Localizes to Dendrites As Well As Axons in Mechanosensitive Chordotonal Neurons, Thomas A Ravenscroft, Ashleigh Jacobs, Mingxue Gu, et al.
An Initial Experience of Completion Hemispherotomy via Magnetic Resonance-Guided Laser Interstitial Therapy, Vijay M Ravindra, Lucia Ruggieri, Nisha Gadgil, et al.
When Phased without Water: Biophysics of Cellular Desiccation, from Biomolecules to Condensates, Paulette Sofia Romero-Perez, Yanniv Dorone, Eduardo Flores, et al.
Compound Heterozygosity of a De Novo Submicroscopic Deletion and an Inherited Frameshift Pathogenic Variant in the PKHD1 Gene in a Fetus With Bilaterally Enlarged and Echogenic Kidneys, Enlarged Abdomen and Oligohydramnios, Takuya Sakyu, Samantha R Stover, Yue Wang, et al.
RagD Auto-Activating Mutations Impair MIT/TFE Activity in Kidney Tubulopathy and Cardiomyopathy Syndrome, Irene Sambri, Marco Ferniani, Giulia Campostrini, et al.
Potential and Pitfalls of Pharmacovigilance Databases in Oncology, Ilana Schlam, Michael S Ewer, and Sandra M Swain
Glia-Neuron Coupling via a Bipartite Sialylation Pathway Promotes Neural Transmission and Stress Tolerance IGlia-Neuron Coupling via a Bipartite Sialylation Pathway Promotes Neural Transmission and Stress Tolerance in Drosophila, Hilary Scott, Boris Novikov, Berrak Ugur, et al.
PIEZO2 in Somatosensory Neurons Controls Gastrointestinal Transit, M Rocio Servin-Vences, Ruby M Lam, Alize Koolen, et al.
The Role of Pharmacotherapy in Treatment of Meningioma: A Systematic Review, Ataollah Shahbandi, Darsh S Shah, Caroline C Hadley, et al.
A Clustering of Heterozygous Missense Variants in the Crucial Chromatin Modifier WDR5 Defines a New Neurodevelopmental Disorder, Lot Snijders Blok, Jolijn Verseput, Dmitrijs Rots, et al.
New Mouse Models With Hypomorphic SUMF1 Variants Mimic Attenuated Forms of Multiple Sulfatase Deficiency, Nicolina Cristina Sorrentino, Maximiliano Presa, Sergio Attanasio, et al.
SPTSSA Variants Alter Sphingolipid Synthesis and Cause a Complex Hereditary Spastic Paraplegia, Siddharth Srivastava, Hagar Mor Shaked, Kenneth Gable, et al.