Duncan NRI Faculty and Staff Publications
The Jan and Dan Duncan Neurological Institute is home to 37 Principal Investigators, more than 400+ scientists and 10 Core labs.
Dan and Duncan Neurological Institute also house the Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories which are focused on epilepsy research and Baylor College's of Medicine's Center for Drug Discovery which is aimed at quick identification and advancement of small molecules to clinical trials.
Since inception, more than 1700 scientific studies have been published, and more than 85 disease-causing genetic mutations have been discovered or co-discovered by our scientists. There are currently 6 active clinical trials and studies.
Submissions from 2023
Alternative Polyadenylation Alters Protein Dosage by Switching Between Intronic and 3’UTR Sites, Nicola de Prisco, Caitlin Ford, Nathan D Elrod, et al.
TFEB and TFE3 Drive Kidney Cystogenesis and Tumorigenesis, Chiara Di Malta, Angela Zampelli, Letizia Granieri, et al.
Neurodevelopmental Deficits and Cell-Type-Specific Transcriptomic Perturbations in a Mouse Model of HNRNPU Haploinsufficiency, Sarah A Dugger, Ryan S Dhindsa, Gabriela De Almeida Sampaio, et al.
A Defect in Mitochondrial Fatty Acid Synthesis Impairs Iron Metabolism and Causes Elevated Ceramide Levels, Debdeep Dutta, Oguz Kanca, Seul Kee Byeon, et al.
Precision Therapy for a Medically Actionable ATP1A3 Variant From a Genomic Medicine Program in an Underserved Population, Cara P Ford, Rebecca O Littlejohn, Ryan German, et al.
Function and Dysfunction of the Dystonia Network: An Exploration of Neural Circuits That Underlie the Acquired and Isolated Dystonias, Jason S Gill, Megan X Nguyen, Mariam Hull, et al.
Function and Dysfunction of the Dystonia Network: An Exploration of Neural Circuits That Underlie the Acquired and Isolated Dystonias, Jason S Gill, Megan X Nguyen, Mariam Hull, et al.
A Comprehensive Drosophila Resource to Identify Key Functional Interactions Between SARS-CoV-2 Factors and Host Proteins, Annabel Guichard, Shenzhao Lu, Oguz Kanca, et al.
Decreasing Mutant ATXN1 Nuclear Localization Improves a Spectrum of SCA1-Like Phenotypes and Brain Region Transcriptomic Profiles, Hillary P Handler, Lisa Duvick, Jason S Mitchell, et al.
SPA-STOCSY: An Automated Tool for Identifying Annotated and Non-annotated Metabolites in High-Throughput NMR Spectra, Xu Han, Wanli Wang, Li-Hua Ma, et al.
An Altered Extracellular Matrix-Integrin Interface Contributes to Huntington’s Disease-Associated CNS Dysfunction in Glial and Vascular Cells, Sarah J Hernandez, Ryan G Lim, Tarik Onur, et al.
A De Novo Missense Variant in EZH1 Associated With Developmental Delay Exhibits Functional Deficits in Drosophila melanogaster, Sharayu V Jangam, Lauren C Briere, Kristy L Jay, et al.
DNA-Encoded Chemical Libraries Yield Non-covalent and Non-peptidic SARS-CoV-2 Main Protease Inhibitors, Ravikumar Jimmidi, Srinivas Chamakuri, Shuo Lu, et al.
Rare Variant Enrichment Analysis Supports GREB1L as a Contributory Driver Gene in the Etiology of Mayer-Rokitansky-Küster-Hauser Syndrome, Angad Jolly, Haowei Du, Christelle Borel, et al.
Hematopoietic Stem and Progenitor Cells Confer Cross-Protective Trained Immunity in Mouse Models, Bailee N Kain, Brandon T Tran, Pamela N Luna, et al.
Evolutionarily Conserved Regulators of Tau Identify Targets for New Therapies, Jiyoen Kim, Maria de Haro, Ismael Al-Ramahi, et al.
Clinical Genome Sequencing: Three Years’ Experience at a Tertiary Children’s Hospital, Runjun D Kumar, Lisa F Saba, Haley Streff, et al.
Antisense Oligonucleotide Therapy Rescues Disturbed Brain Rhythms and Sleep in Juvenile and Adult Mouse Models of Angelman Syndrome, Dongwon Lee, Wu Chen, Heet Naresh Kaku, et al.
Automating the High-Throughput Screening of Protein-Based Optical Indicators and Actuators, Jihwan Lee, Beatriz Campillo, Shaminta Hamidian, et al.
The Melanocortin Action Is Biased Toward Protection From Weight Loss in Mice, Hongli Li, Yuanzhong Xu, Yanyan Jiang, et al.
Integration of Transcriptome-Wide Association Study With Neuronal Dysfunction Assays Provides Functional Genomics Evidence for Parkinson’s Disease Genes, Jiayang Li, Bismark Kojo Amoh, Emma McCormick, et al.
Exploring Therapeutic Strategies for Infantile Neuronal Axonal Dystrophy (INAD/PARK14), Guang Lin, Burak Tepe, Geoff McGrane, et al.
Single-Cell Multi-Omics Integration for Unpaired Data by a Siamese Network with Graph-Based Contrastive Loss, Chaozhong Liu, Linhua Wang, and Zhandong Liu
Aging Fly Cell Atlas Identifies Exhaustive Aging Features at Cellular Resolution, Tzu-Chiao Lu, Maria Brbić, Ye-Jin Park, et al.
Co-Transmitting Interneurons in the Mouse Olfactory Bulb Regulate Olfactory Detection and Discrimination, Ariel M Lyons-Warren, Evelyne K Tantry, Elizabeth H Moss, et al.