The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.

Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.

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Submissions from 2023

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Dermatological Concerns for Women and Girls With Turner Syndrome, David Rodriguez-Buritica, Meaghan Mones, Siddharth K Prakash, et al.

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Design and Development of a Clot Burst Pressure Device to Investigate Resuscitation Strategies, Atharwa R Mankame, Jacob B Schriner, Max A Skibber, et al.

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Dexmedetomidine Alters The Inflammatory Profile of Rat Microglia In Vitro, Michael C Scott, Candice M Haase, Scott D Olson, et al.

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Direct Modulators of K-Ras–Membrane Interactions, Johannes Morstein, Rebika Shrestha, Que N Van, et al.

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Disease Modeling and Gene Correction of LGMDR21 iPSCs Elucidates the Role of POGLUT1 in Skeletal Muscle Maintenance, Regeneration, and the Satellite Cell Niche, Jose L Ortiz-Vitali, Jianbo Wu, Nasa Xu, et al.

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DNA Methylation Analysis Is Used To Identify Novel Genetic Loci Associated With Circulating Fibrinogen Levels in Blood, Julie Hahn, Jan Bressler, Arce Domingo-Relloso, et al.

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Dural Sinus Narrowing In Patients With Spontaneous Anterior Skull Base Cerebrospinal Fluid Leak, Karim W Asi, Brian H Cameron, Elliot R Friedman, et al.

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Endotrophin Neutralization Through Targeted Antibody Treatment Protects From Renal Fibrosis in a Podocyte Ablation Model, Yu A An, Wei Xiong, Shiuhwei Chen, et al.

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Energy Intake at the Intersection of the Clock and Ageing, Kristin Eckel-Mahan

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Entry Receptor LDLRAD3 Is Required for Venezuelan Equine Encephalitis Virus Peripheral Infection and Neurotropism Leading to Pathogenesis in Mice, Natasha M Kafai, Hana Janova, Matthew D Cain, et al.

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Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9, Antoine Weihs, Layal Chaker, Tiphaine C Martin, et al.

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Estimating Heritability Explained By Local ancestry and Evaluating Stratification Bias in admixture Mapping From Summary Statistics, Tsz Fung Chan, Xinyue Rui, David V Conti, et al.

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Estrogen-Related Receptor Gamma Gene Therapy Promotes Therapeutic Angiogenesis and Muscle Recovery in Preclinical Model of PAD, Danesh H Sopariwala, Andrea S Rios, Addison Saley, et al.

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Evaluating the Use of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, Matthew O Goodman, Alyna T Khan, et al.

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Exercise and Ischemia-Activated Pathways in Limb Muscle Angiogenesis and Vascular Regeneration, Vihang A Narkar

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Expansion of the Genotypic and Phenotypic Spectrum of CTCF-Related Disorder Guides Clinical Management: 43 New Subjects and a Comprehensive Literature Review, Hannah Gabriela Valverde de Morales, Hsiao-Lin V Wang, Kathryn Garber, et al.

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Extracellular Matrix (ECM) and Fibrosis in Adipose Tissue: Overview and Perspectives, Kai Sun, Xin Li, and Philipp E Scherer

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Gender Differences in a Mouse Model of Hepatocellular Carcinoma Revealed Using Multi-Modal Imaging, Brian J Engel, Vincenzo Paolillo, Md Nasir Uddin, et al.

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Gene-Educational Attainment Interactions in a Multi-population Genome-Wide Meta-Analysis Identify Novel Lipid Loci, Lisa de Las Fuentes, Karen L Schwander, Michael R Brown, et al.

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Gene Expression In Mice With Endothelium-Specific Telomerase Knockout, Zhanguo Gao, Yongmei Yu, Yulin Dai, et al.

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Genetic Associations Between Sleep Traits and Cognitive Ageing Outcomes in the Hispanic Community Health Study/Study of Latinos, Yuan Zhang, Michael Elgart, Einat Granot-Hershkovitz, et al.

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Genetic Inactivation of β-Catenin Is Salubrious, Whereas Its Activation Is Deleterious in Desmoplakin Cardiomyopathy, Melis Olcum, Siyang Fan, Leila Rouhi, et al.

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Genetic Loci of Beta-Aminoisobutyric Acid Are Associated With Aging-Related Mild Cognitive Impairment, Einat Granot-Hershkovitz, Brian Spitzer, Yunju Yang, et al.

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GLP1 Receptor Agonists-Effects beyond Obesity and Diabetes, Sydney S Wilbon and Mikhail G Kolonin

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Glycolysis Regulates Kras Plasma Membrane Localization and Function Through Defined Glycosphingolipids, Junchen Liu, Ransome van der Hoeven, Walaa E Kattan, et al.