The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2026
Adipocyte-Specific Deletion of Sine Oculis Homeobox Homolog 1 Inhibits Lipolysis and Reduces Skin Fibrosis, Nancy Wareing, Tingting W Mills, Scott Collum, et al.
A Distinct Form of Fat Fibrosis Is Linked to Insulin Resistance in People With HIV, Diana L Alba, Alaa Abdellatif, Moon Kyung Choi, et al.
Adoptive Cell Therapies for Glioblastoma: A Quest for Cures from Within, Jia-Shiun Leu, Xin Ge, Charles Robin Yu, et al.
Advances in Glp-1 Receptor Agonists Delivery Systems for Obesity and Diabetes, Mehrnaz Abbasi, Kai Sun, Kevin W Huggins, et al.
Affinity-Optimized TROP2 Antibodies Support Potent Antitumor Activity in Antibody-Drug Conjugates, Aiko Yamaguchi, Junping Hong, Leike Li, et al.
AMC-F1 Regulates Mitochondria-Autophagy Crosstalk Independent of Nutrient Stress, Yuqin Wang, Raksha K Rao, Trung Vu, et al.
An Integrated Lifestyle-, Genetic- and Metabolomics-Based Prediction Model for Mild Cognitive Aging in the HCHS/SOL, Annah B Wyss, Yana Hrytsenko, Linfeng Hu, et al.
An Obligatory Role for AgRP Neurons in Maintaining Body Temperature During Time-Restricted Feeding, Cunjin Su, Jing Cai, Yuanzhong Xu, et al.
Antibody-Oligonucleotide Conjugates: An Emerging Modality for Precision RNA Therapeutics, Chen-Hsu Yu, Summer Y Y Ha, Zhiqiang An, et al.
Antibody-Oligonucleotide Conjugates: An Emerging Modality for Precision RNA Therapeutics, Chen-Hsu Yu, Summer Y Y Ha, Zhiqiang An, et al.
Anti-Egfr Liposomal Drug Delivery System Loaded With AGY2 Potentiates the Anti-Cancer Effect of AGY2 Against Egfr Expressed Pancreatic Cancer, Raviteja Bulusu, Esther Frimpong, Joy Okoro, et al.
APOE and Plasma AD Biomarkers: The Role of Genetic Ancestry in Hispanics/Latinos, Caitlin Cheung, Natasha Z Anita, Paola Filigrana, et al.
Associations of Blood Biomarkers of Glial Cell Dysfunction and Neuronal Injury With Future Cognitive Decline and Incident Dementia, Srishti Shrestha, Xiaoqian Zhu, B Gwen Windham, et al.
Astrocytic Sox9 Overexpression in Alzheimer’s Disease Mouse Models Promotes Aβ Plaque Phagocytosis and Preserves Cognitive Function, Dong-Joo Choi, Sanjana Murali, Wookbong Kwon, et al.
Blood Flow Regulates Metabolism in Hematopoietic Development, Pamela L Wenzel
Brain-Engrafted Monocyte-Derived Macrophages From Blood and Skull-Bone Marrow Exhibit Distinct Properties, Siling Du, Feiya Ou, Antoine Drieu, et al.
Brain Perivascular Macrophages Regulate Endothelial Cell Function via a cMAF-Dependent Transcriptional Program in Mouse and Human, Simone Brioschi, Julia A Belk, Steffen E Storck, et al.
CD44v9 as a Therapeutic Target for Antibody-Drug Conjugate in Advanced Breast Cancer, Dileep R Reddy, McKenna E Flynn, Yasuaki Anami, et al.
cellSTAAR: Incorporating Single-Cell-Sequencing-Based Functional Data To Boost Power in Rare Variant Association Testing of Noncoding Regions, Eric Van Buren, Yi Zhang, Xihao Li, et al.
Claudins Interact With Lilrb Immune Inhibitory Receptors to Promote Myeloid Immunosuppression in Cancer, Xiaoye Liu, Ryan Huang, Zhiqiang Ku, et al.
Complement Anaphylatoxin C5a-Induced Mouse Lymphatic Functions Modulate Interactions Between Endothelial Cells and T Lymphocytes, Haydn E Rich, Yi-Dong Li, Kathryn D Hok, et al.
Comprehensive Prediction Analysis of Novel Noncoding Regulatory Variants Identified in the MicroRNA Binding Regions in Complement System Genes, Anthony Shadid, Haydn E Rich, Kathryn D Hok, et al.
Co-Occurring Clonal Hematopoiesis Exhibits Strong Selection and High Leukemia Risk, Kara M Barnao, Aubrey K Hubbard, Irenaeus C C Chan, et al.
Corticotropin-Releasing Factor Neurons in the Bed Nucleus of the Stria Terminalis Modulate Avoidance Behaviors and Feeding, Juan Manuel Romero, Shae-Marie Stafford-Trujillo, Mitzy Mendoza, et al.
Cost Utility Analysis of Fluticasone Exhalation Delivery System Versus Budesonide Nasal Irrigation for Chronic Rhinosinusitis With Nasal Polyps, Daniel Xiao, Martin J Citardi, William C Yao, et al.