The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.

Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.

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Submissions from 2022

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MRI Free Water as a Biomarker for Cognitive Performance: Validation in the MarkVCID Consortium, Pauline Maillard, Laura J Hillmer, Hanzhang Lu, et al.

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Rare Genetic Variants Explain Missing Heritability in Smoking, Seon-Kyeong Jang, Luke Evans, Allison Fialkowski, et al.

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Selective IgA Deficiency in Spontaneously Hypertensive Rats With Gut Dysbiosis, Piu Saha, Blair Mell, Rachel M Golonka, et al.

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SIRPα Mediates IGF1 Receptor in Cardiomyopathy-Induced by Chronic Kidney Disease, Sandhya S Thomas, Jiao Wu, Giovanni Davogustto, et al.

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Temporal and Spatial Metabolite Dynamics Impart Control in Adipogenesis, Kristin Eckel-Mahan

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The Challenges and Opportunities of scRNA-Seq in COVID-19 Research and Clinical Translation, Wendao Liu, Xiaohua Ye, Zhiqiang An, et al.

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The Circular RNA Edis Regulates Neurodevelopment and Innate Immunity, Xiao-Peng Xiong, Weihong Liang, Wei Liu, et al.

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The Rheumatoid Arthritis Drug Auranofin Lowers Leptin Levels and Exerts Antidiabetic Effects in Obese Mice, Aaron R Cox, Peter M Masschelin, Pradip K Saha, et al.

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Uncloaking Cell-Impermeant Gold Nanorods Via Tumor Microenvironmental Cathepsin B Facilitates Cancer Cell Penetration and Potent Radiosensitization, Subhiksha Raghuram, Yuri Mackeyev, Jessica Symons, et al.

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Whole Genome Sequence Analysis of Blood Lipid Levels in >66,000 Individuals, Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, et al.

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Whole Genome Sequencing Identifies Structural Variants Contributing to Hematologic Traits in the Nhlbi topmed Program, Marsha M Wheeler, Adrienne M Stilp, Shuquan Rao, et al.