The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2025
Protocol for Establishing Genetically Engineered Murine Lung Organoids Mimicking Cell Plasticity and Regeneration, Bongjun Kim and Jae-Il Park
Protocol To Detect m22G Modification on Single tRNA Iso-Decoders by Immuno-Northern Blotting, Sseu-Pei Hwang, Katherine Barondeau, and Catherine Denicourt
Psilocybin Treatment Extends Cellular Lifespan and Improves Survival of Aged Mice, Kosuke Kato, Jennifer M Kleinhenz, Yoon-Joo Shin, et al.
Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease, Bernardo Casso-Chapa, Norma Alicia Vazquez González, Nhat-Tu Le, et al.
Rescue of Male Infertility by Human PRSS55 in Transgenic Mice Establishes a Contraceptive Research Model, Courtney M Sutton, Kohei Umezu, Daisuke Mashiko, et al.
Serotonin Neurons Integrate GABA and Dopamine Inputs To Regulate Meal Initiation, Kristine M Conde, HueyZhong Wong, Shuzheng Fang, et al.
Serum Endotrophin Relates to Blood Pressure in Young South Asian Women but Not White Women: Evidence of Ethnic Variation in Its Early Vascular Implications, Ravi Retnakaran, Dawei Bu, Jiajie Pu, et al.
SLB-msSIM: A Spectral Library-Based Multiplex Segmented SIM Platform for Single-Cell Proteomic Analysis, Lakmini Senavirathna, Cheng Ma, Van-An Duong, et al.
Somatostatin Receptor 2 Overexpression in Hepatocellular Carcinoma: Implications for Cancer Biology and Therapeutic Applications, Servando Hernandez Vargas, Solmaz Aghaamiri, Jack T Adams, et al.
SSTR2-Targeted Theranostics in Hepatocellular Carcinoma, Majid Momeny, Solmaz AghaAmiri, Servando Hernandez Vargas, et al.
Structural Basis for the Substrate Specificity of Helix pomatia AMP Deaminase and a Chimeric ADGF Adenosine Deaminase, Gundeep Kaur, John R Horton, George Tzertzinis, et al.
SWI/SNF Complex-Mediated ZNF410 Cooperative Binding Maintains Chromatin Accessibility and Enhancer Activity, Siyuan Xu, Chuxuan Peng, Ren Ren, et al.
The Genomes of Nematode-Trapping Fungi Provide Insights Into the Origin and Diversification of Fungal Carnivorism, Yani Fan, Minghao Du, Weiwei Zhang, et al.
The microRNA miR-30a Blocks Adipose Tissue Fibrosis Accumulation in Obesity, Pradip K Saha, Robert Sharp, Aaron R Cox, et al.
Three-Dimensional Printed Models to Accelerate Resident Surgical Learning Curve for Standard Endoscopic Sinus Surgery Techniques, Jumah G Ahmad, Alexander J Citardi, Amber U Luong, et al.
Type 2 Diabetes Polygenic Risk Score Interactions with Lifestyle Risk Factors in Black Americans, Ashley W Scadden, Aastha Kakar, Elizabeth M Litkowski, et al.
Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants, Kruthika R Iyer, Shoa L Clarke, Rodrigo Guarischi-Sousa, et al.
Whole Genome Sequence Analysis of Low-Density Lipoprotein Cholesterol Across 246 K Individuals, Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, et al.
Whole-Genome Sequence-Based Association Analysis of African American Individuals With Bipolar Disorder and Schizophrenia, Runjia Li, Sarah A Gagliano Taliun, Kevin Liao, et al.
Whole Genome Sequencing Analysis of Body Mass Index Identifies Novel African Ancestry-Specific Risk Allele, Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, et al.
Submissions from 2024
Aba-Mediated Regulation of Rice Grain Quality and Seed Dormancy Via The Nf-Yb1-Slrl2-Bhlh144 Module, Jin-Dong Wang, Jing Wang, Li-Chun Huang, et al.
Admixture Mapping of Cognitive Function in Diverse Hispanic and Latino Adults: Results From the Hispanic Community Health Study/Study of Latinos, Rui Xia, Xueqiu Jian, Amanda L Rodrigue, et al.
A Genetic Association Study of Circulating Coagulation Factor VIII and Von Willebrand Factor Levels, Paul S de Vries, Paula Reventun, Michael R Brown, et al.
A Light-Responsive Neural Circuit Suppresses Feeding, Hailan Liu, Na Qu, Natalia Valdez Gonzalez, et al.
Androgen Deprivation Induces Neuroendocrine Phenotypes in Prostate Cancer Cells Through CREB1/EZH2-Mediated Downregulation of Rest, Dayong Zheng, Yan Zhang, Sukjin Yang, et al.