The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.

Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.

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Submissions from 2026

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Structural-Functional Analyses of the Huntingtin/HAP40 Complex in Drosophila and Humans, Stephen M Farmer, Amanda Solbach, Shiyu Xu, et al.

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SUPT16H-Associated Neurodevelopmental Disorder and Neurocristopathy: Genetic and Phenotypic Spectrum, Eunhye Lee, Seungmin Sim, Hee-Jung Choi, et al.

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Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence-Based Expert Review, Andrew Thamboo, Deanna Gigliotti, Eugenio De Corso, et al.

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Targeting Nuclear Receptors in Muscular Dystrophies and Regenerative Myogenesis, Eira Mann, Hoang Vu, Vihang A Narkar, et al.

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Telomerase Knockout in Myeloid Cells Predisposes Mice to Foam Cell Formation, Dyslipidemia, Lung Fibrosis, and Cardiac Dysfunction, Zhanguo Gao, Yongmei Yu, David Wiggins, et al.

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Telomere-to-Telomere Genome Assembly and a Pangenome for the Rat, Kai Li, Julia L Ciosek, Sergey Koren, et al.

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The Neuroprotective Effects of Alpha-Tocopherol as an Anti-Inflammatory Agent: Mechanistic Insights and Therapeutic Challenges, Megumi H Seese and Yuanzhong Xu

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Transfusion in Transit: A Decade of Prehospital Blood Transfusion in Pediatric Trauma, Krysta M Sutyak, Eunise C Chen, Lea Mock, et al.

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Tumor Radiosensitization With Gold Nanoparticles: Evolving Strategies to Improve Tumoral Gold Uptake and Catalyze Future Clinical Translation, Prapannajeet Biswal, Geraldine V Vijay, Gabrielle Krouse, et al.

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Unbiased Avidity-Based Isolation of Antigen-Specific T Cells, Amanda Montoya, Meredith L Frank, Peixin Jiang, et al.

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Understanding Hypertensive Renal Injury: A Well-Structured Approach, Peter A Doris

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Water-Soluble Fullerene Derivatives Mitigate Cranial Radiation-Induced Neuroinflammation and Cognitive Dysfunction, Naren Gundapaneni, Iona Hill, Lydia W T Cheung, et al.

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Weight Loss and Chronic Rhinosinusitis in the Obese Population: Associations With Disease Risk and Burden, Zain Mehdi, Akshay R Prabhakar, Jagan M R Dwarampudi, et al.

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Whole Genome Sequencing Analysis of Over 3500 Individuals Dementia-Free Over 85 Years Old, Gina M Peloso, Dongyu Wang, Sabrina M Abbruzzese, et al.

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γδ T Cells at the Interface of Innate and Adaptive Immunity in Cancer, Arnau Solé Casaramona, Martin F Bachmann, Eva Sevick-Muraca, et al.

Submissions from 2025

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177Lu-Labeled Antibody-Drug Conjugate: A Dual-Mechanistic Treatment Modality in Solid Tumors, Aiko Yamaguchi, Chisato M Yamazaki, Yasuaki Anami, et al.

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Acute Kidney Injury Is Associated With Elevated Urinary Endotrophin, Amanda J Clark, Brenda Mendoza Flores, Marie Christelle Saade, et al.

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Additional Evidence From a Case Report Supports a Novel Hypothesis on the Association Between Complex Regional Pain Syndrome and Lymphedema, M Mark Melin, John C Rasmussen, Melissa B Aldrich, et al.

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Advances in Artificial Intelligence for Glioblastoma Radiotherapy Planning and Treatment, Reid Master, Nesha Rubin, James Sampson, et al.

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Aging in Mice Alters Regionally Enriched Striatal Astrocytes, Kay E Linker, Violeta Duran-Laforet, Matthias Ollivier, et al.

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A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals From Diverse Populations, Pavithra Nagarajan, Thomas W Winkler, Amy R Bentley, et al.

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Allergic Fungal Rhinosinusitis Diagnosis, Management, Associated Conditions, Pathophysiology, and Future Directions: Summary of a Multidisciplinary Workshop, Lauren T Roland, Cecelia Damask, Amber U Luong, et al.

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Allergic Fungal Rhinosinusitis Diagnosis, Management, Associated Conditions, Pathophysiology, and Future Directions: Summary of a Multidisciplinary Workshop, Lauren T Roland, Cecelia Damask, Amber U Luong, et al.

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Alterations in DNA Methylation, Proteomic, and Metabolomic Profiles in African Ancestry Populations with APOL1 Risk Alleles, Xinruo Zhang, Ashley W Scadden, Amarnath Marthi, et al.

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A Mouse Model of Lipoatrophy Reveals Relationships Between Beige Fat Appearance and Female Fertility, Elizabeth S Anaya, William Dion, Pradip K Saha, et al.