The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2025
Genome-Wide Association Study Provides Novel Insight Into the Genetic Architecture of Severe Obesity, Mohanraj Krishnan, Mohammad Yaser Anwar, Anne E Justice, et al.
Genomic and Phenotypic Correlates of Mosaic Loss of Chromosome Y in Blood, Yasminka A Jakubek, Xiaolong Ma, Adrienne M Stilp, et al.
Glutamatergic Regulation of miRNA-Containing Intraluminal Vesicle Trafficking and Extracellular Vesicle Secretion From Cortical Neurons, Marcela Bertolio, Qiyi Li, Francesca E Mowry, et al.
GSK-3484862, a DNMT1 Degrader, Promotes DNMT3B Expression in Lung Cancer Cells, Qin Chen, Swanand Hardikar, Kimie Kondo, et al.
Identification and Functional Assessment of Candidate Causal Cis-Regulatory Variants Underlying Electrocardiographic QT Interval GWAS Loci, Supraja Kadagandla, Lavanya Gunamalai, Dongwon Lee, et al.
IDH Status Dictates oHSV Mediated Metabolic Reprogramming Affecting Anti-tumor Immunity, Upasana Sahu, Matthew P Mullarkey, Sara A Murphy, et al.
Immunomodulatory Effects of Gold Nanoparticles: Impacts on Immune Cells and Mechanisms of Action, Khadijeh Koushki, Prapannajeet Biswal, Geraldine Vidhya Vijay, et al.
Impact of Common Variants on Brain Gene Expression From RNA to Protein to Schizophrenia Risk, Qiuman Liang, Yi Jiang, Annie W Shieh, et al.
Impacts of Radiation on Metabolism and Vascular Cell Senescence, Junichi Abe, Khanh Chau, Anahita Mojiri, et al.
Implications and Pathophysiology of Neuroinflammation in Pediatric Patients With Traumatic Brain Injury: An Updated Review, Shalin S Shah, Arya J Shetty, David T Johnston, et al.
Insights into the Role of the Glymphatic System in the Pathogenesis of Post-hemorrhagic Hydrocephalus, Ahmed T Massoud, Dillon A Noltensmeyer, Jenifer Juranek, et al.
Investigating Machine Learning Algorithms to Classify Label-Free Images of Pancreatic Neuroendocrine Neoplasms, Noelle Daigle, Shuyuan Guan, Suzann Duan, et al.
Islet Single-Cell Transcriptomic Profiling During Obesity-Induced Beta Cell Expansion in Female Mice, Peter M Masschelin, Scott A Ochsner, Sean M Hartig, et al.
KAP1 Promotes Gastric Adenocarcinoma Progression by Activating Hippo/YAP1 Signaling via Binding to HNRNPAB, Shumei Song, Yibo Fan, Gengyi Zou, et al.
Leptin as a Key Driver for Organ Fibrogenesis, Xue-Nan Sun, Shiuhwei Chen, Shangang Zhao, et al.
Limitations of the Radiotheranostic Concept in Neuroendocrine Tumors Due to Lineage-Dependent Somatostatin Receptor Expression on Hematopoietic Stem and Progenitor Cells, Nghia Nguyen, Yu Min, Jennifer Rivière, et al.
Longitudinal Associations of Epigenetic Aging With Cognitive Aging in Hispanic/Latino Adults From the Hispanic Community Health Study/Study of Latinos, Myriam Fornage, Wassim Tarraf, Rui Xia, et al.
Mapping Cardiac Electrical Abnormalities in Rodents, Ashish Kapoor and Peter A Doris
Mechanisms and Environmental Factors Shaping the Ecosystem of Brain Macrophages, Silvia Penati, Simone Brioschi, Zhangying Cai, et al.
Methylation Risk Score of C-reactive Protein Associates Sleep Health With Related Health Outcomes, Ziqing Wang, Danielle A Wallace, Brian W Spitzer, et al.
Methylome-Wide Association Analyses of Lipids and Modifying Effects of Behavioral Factors in Diverse Race and Ethnicity Participants, Yao Hu, Jeff Haessler, Jessica I Lundin, et al.
Microglial Phagocytosis in Epilepsy: Mechanisms and Impact, Abhijeet S Barath and Long-Jun Wu
Microglial TREM2 Promotes Phagocytic Clearance of Damaged Neurons After Status Epilepticus, Dale B Bosco, Vaclav Kremen, Koichiro Haruwaka, et al.
Monte Carlo Study of Gold Nanoparticle-Mediated Radiosensitization Effects Using Nanoscale Cell Model Combined With Fractal-Based DNA Model, Amrit Kaphle, Sandun Jayarathna, Sunil Krishnan, et al.
MT1-Mmp Inhibition Rejuvenates Ageing Brain and Rescues Cognitive Deficits in Obesity, Pallavi Asthana, Liguo Li, Lin Lu, et al.