The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2024
Genome-Wide Association Study Meta-Analysis of Neurofilament Light (NFL) Levels in Blood Reveals Novel Loci Related to Neurodegeneration, Shahzad Ahmad, Mohammad Aslam Imtiaz, Aniket Mishra, et al.
Global Trend in Exosome Isolation and Application: An Update Concept in Management of Diseases, Mohammadhassan Omrani, Hanieh Beyrampour-Basmenj, Rana Jahanban-Esfahlan, et al.
G Protein Selectivity Profile of GPR56/ADGRG1 and Its Effect on Downstream Effectors, Raida Jallouli, Ana L Moreno-Salinas, Andréanne Laniel, et al.
Human Brain Glycoform Coregulation Network and Glycan Modification Alterations in Alzheimer's Disease, Qi Zhang, Cheng Ma, Lih-Shen Chin, et al.
Hunting for Heroes: Brain Neurons Mediating GLP-1R Agonists in Obesity Treatment, Yuhan Cao and Qingchun Tong
Inter-Individual Variations in Circadian Misalignment-Induced NAFLD Pathophysiology in Mice, Nobuya Koike, Yasuhiro Umemura, Hitoshi Inokawa, et al.
Intracranial Volume Is Driven by Both Genetics and Early Life Exposures: The SOL-INCA-MRI Study, Tamar Sofer, Einat Granot-Hershkovitz, Wassim Tarraf, et al.
Intratumoral Microbiome of Adenoid Cystic Carcinomas and Comparison With Other Head and Neck Cancers, Tatiana V Karpinets, Yoshitsugu Mitani, Chia-Chi Chang, et al.
Itaconate Transporter SLC13A3 Impairs Tumor Immunity via Endowing Ferroptosis Resistance, Heng Lin, Kole Tison, Yuheng Du, et al.
Keep Fingers on the CpG Islands, Xing Zhang, Robert M Blumenthal, and Xiaodong Cheng
Key Variants via the Alzheimer's Disease Sequencing Project Whole Genome Sequence Data, Yanbing Wang, Chloé Sarnowski, Honghuang Lin, et al.
Large T Antigen Mediated Target Gene Replication Improves Site-Specific Recombination Efficiency, Zening Wang, Chuan Chen, and Xin Ge
Leptin Reduction as a Required Component for Weight Loss, Shangang Zhao, Na Li, Wei Xiong, et al.
LILRB3 Supports Immunosuppressive Activity of Myeloid Cells and Tumor Development, Ryan Huang, Xiaoye Liu, Jaehyup Kim, et al.
LILRB4 on Multiple Myeloma Cells Promotes Bone Lesion by P-SHP2/Nf-κB/Relt Signal Pathway, Hongying Wang, Lei Wang, Huiwen Luan, et al.
Low Molecular Weight Heparin Decreases Pro-coagulant Activity in Clinical MSC Products, Jacob B Schriner, Fabio Triolo, Brijesh S Gill, et al.
Machine Learning Models for Predicting Blood Pressure Phenotypes by Combining Multiple Polygenic Risk Scores, Yana Hrytsenko, Benjamin Shea, Michael Elgart, et al.
Matrin3 Mediates Differentiation Through Stabilizing Chromatin Loop-Domain Interactions and YY1 Mediated Enhancer-Promoter Interactions, Tianxin Liu, Qian Zhu, Yan Kai, et al.
Mechanisms and Metabolic Consequences of Adipocyte Progenitor Replicative Senescence, Tonghui Lin, Aftab Mohammad, Mikhail G Kolonin, et al.
Mechanistic Insights Into Metabolic Function of Dynamin-Related Protein 1, Xin Li, Katherine Pham, Jazmin Ysaguirre, et al.
Mitochondrial Permeability Transition Dictates Mitochondrial Maturation Upon Switch in Cellular Identity of Hematopoietic Precursors, Sandeep P Dumbali, Paulina D Horton, Travis I Moore, et al.
Molecular and Physiological Changes in the SpaceX Inspiration4 Civilian Crew, Christopher W Jones, Eliah G Overbey, Jerome Lacombe, et al.
Molecular Profiling of Braf-V600E-Mutant Metastatic Colorectal Cancer in the Phase 3 Beacon CRC Trial, Scott Kopetz, Danielle A Murphy, Jie Pu, et al.
MondoA and AKI and AKI-to-CKD Transition, Shihomi Maeda, Shinsuke Sakai, Yoshitsugu Takabatake, et al.
Multivalent Cytomegalovirus Glycoprotein B Nucleoside Modified mRNA Vaccines Did Not Demonstrate a Greater Antibody Breadth, Hsuan-Yuan Wang, Leike Li, Cody S Nelson, et al.