The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2026
Development and Validation of a Harmonized Memory Score for Multicenter Alzheimer’s Disease and Related Dementia Research, Mark Sanderson-Cimino, Alden L Gross, Leslie S Gaynor, et al.
Development of a Multiplex Assay for Early Detection of Pancreatic Cancer in High-Risk Groups, Sheng Pan, Ramesh Karki, Lisa A Lai, et al.
Diversity and Immune Dynamics of Choroid Plexus Macrophages Are Shaped by Distinct Developmental Origins, Siling Du, Khai M Nguyen, Alina Ulezko Antonova, et al.
Does HLA-B27 Status Influence Ixekizumab Efficacy in Axial Spondyloarthritis? Results From the COAST-V, COAST-W, and COAST-X Trials, John D Reveille, Martin Rudwaleit, Proton Rahman, et al.
Dupilumab for Patients With Allergic Fungal Rhinosinusitis, Amber U Luong, Joshua M Levy, Sarah K Wise, et al.
Ectopic B Lymphocyte Follicles Exacerbate Ischemic Brain Damage via MIF-CD74/CXCR4 and Interferon Signaling, Sheng Yang, Hang Zhang, Lu-Lu Xu, et al.
ERK-Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells, Xiaolei Zhao, Shannon Erhardt, Li Tang, et al.
Estimating Population Structure Using Epigenome-Wide Methylation Data, Ziqing Wang, Kent D Taylor, Jerome I Rotter, et al.
Fibulin-4 Expressed in Metastatic Breast Cancer Is a Target of Peptide-Based Imaging Probes and Experimental Therapeutics, Alexes C Daquinag, Sukhen C Ghosh, Solmaz AghaAmiri, et al.
Freeze-Dried, Not Frozen: Lyophilized Mesenchymal Stromal Cell-Derived Extracellular Vesicles and Therapeutic Function in Neuroinflammatory Models, Janet R Ashley, Aidan M Collier, Scott D Olson, et al.
Functional Characterization of UHRF1 Variants in Facilitating DNA Methylation, Bigang Liu, Kaila Nayvelt, Swanand Hardikar, et al.
Functional Requirement for Dicer Helicase Arginine Methylation in 26 G siRNA Biogenesis and Oocyte Meiotic Program, Nick Newkirk, Shin-Yu Chen, Tokiko Furuta, et al.
Genetic Architecture of White Matter Microstructure Captured by Unsupervised Deep Representation Learning of Fractional Anisotropy Maps, Xingzhong Zhao, Ziqian Xie, Wei He, et al.
Genome-Wide Gene-Sleep Interaction Study Identifies Novel Lipid Loci in 732,564 Participants, Raymond Noordam, Wenyi Wang, Pavithra Nagarajan, et al.
GH Alters Lymphatic Vessels in Female Mice and STAT5 Phosphorylation in Human Lymphatic Endothelial Cells, Christopher Walsh, Emily Scott, Elise Wagner, et al.
Glutamatergic Dysfunction of Astrocytes in Paraventricular Nucleus of Thalamus Contributes to Adult Anxiety Susceptibility in Adolescent Ethanol Exposed Mice, Aubrey Bennett, Hyunjung Kim, David Thomas, et al.
Glutamatergic Projection Neurons in the Basal Forebrain Underlie Learned Olfactory Associational Valence Assignments, Pey-Shyuan Chin, Zhuokun Ding, Mikhail Kochukov, et al.
Glycosphingolipids Regulate Phosphatidylserine Transport Machinery That Operates at Er-PM Contact Sites, Ritchel Gannaban, Sher Ali, Wei Chen, et al.
Human-centered Design of Patient Interviews: Capturing the Experiences of Patients Recovering From Emergency Abdominal Surgery, Jenna L Marquard, Christie L Martin, Elizabeth C Wick, et al.
Human Microglia in Brain Assembloids Display Region-Specific Diversity and Respond to Hyperexcitable Neurons Carrying SCN2A Mutation, Jiaxiang Wu, Xiaoling Chen, Jingliang Zhang, et al.
Identification of a Cytokine Biomarker for Prognostic Modeling of Breast Cancer-Related Lymphedema, Alison J Wu, Neil Lin, Jie Su, et al.
Immune Checkpoint Inhibitor-Induced Cardiotoxicity: From Immune Mechanisms to Clinical Surveillance and Targeted Therapies, Nathan K Chen, Kathryn D Hok, Narsi Chokshi, et al.
Inhibition of EPAC1 Prevents Neuronal Death Mediated by Diesel Exhaust Particles in Ferroptotic Cell Death Conditions, Hong Yan, Leshan Zhang, Ana L Manzano-Covarrubias, et al.
Key Regulatory Roles of PRDM1 in Human Nk-Cell Differentiation and Activation, Xuxiang Liu, Yunfei Shi, Jibin Zhang, et al.
Large-Scale Blood Pressure Gwas Accounting for Gene-Depression Interactions in 564,680 Individuals From Diverse Populations, Songmi Lee, Clint L Miller, Amy R Bentley, et al.