The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2025
Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease, Bernardo Casso-Chapa, Norma Alicia Vazquez González, Nhat-Tu Le, et al.
Relationship Between TRPM4 RS8104571 Genotype, Circulating TRPM4 and SUR1, and Clinical Outcome Following Traumatic Brain Injury, Joseph D Krocker, Madeline E Cotton, Janet R Ashley, et al.
Restricting Metabolic Plasticity Enhances Stress Adaptation Through the Modulation of Pdh and HIF1A in TRAP1-Depleted Colon Cancer, Hong-Yuan Tsai, Miao-Hsueh Chen, Jihye Yun, et al.
Rezafungin for Suppressive Therapy of Candida auris in a Patient With a Left Ventricular Assist Device (LVAD), Matthew A Stack, Luis Ostrosky-Zeichner, Rodrigo Hasbun, et al.
Rhythm Is Essential: Unraveling the Relation Between the Circadian Clock and Cancer, Olajumoke Ogunlusi, Abantika Ghosh, Mrinmoy Sarkar, et al.
Serotonin Neurons Integrate GABA and Dopamine Inputs To Regulate Meal Initiation, Kristine M Conde, HueyZhong Wong, Shuzheng Fang, et al.
Serum Endotrophin Relates to Blood Pressure in Young South Asian Women but Not White Women: Evidence of Ethnic Variation in Its Early Vascular Implications, Ravi Retnakaran, Dawei Bu, Jiajie Pu, et al.
SLB-msSIM: A Spectral Library-Based Multiplex Segmented SIM Platform for Single-Cell Proteomic Analysis, Lakmini Senavirathna, Cheng Ma, Van-An Duong, et al.
Somatostatin Receptor 2 Overexpression in Hepatocellular Carcinoma: Implications for Cancer Biology and Therapeutic Applications, Servando Hernandez Vargas, Solmaz Aghaamiri, Jack T Adams, et al.
SSTR2-Targeted Theranostics in Hepatocellular Carcinoma, Majid Momeny, Solmaz AghaAmiri, Servando Hernandez Vargas, et al.
Structural Basis for the Substrate Specificity of Helix pomatia AMP Deaminase and a Chimeric ADGF Adenosine Deaminase, Gundeep Kaur, John R Horton, George Tzertzinis, et al.
SWI/SNF Complex-Mediated ZNF410 Cooperative Binding Maintains Chromatin Accessibility and Enhancer Activity, Siyuan Xu, Chuxuan Peng, Ren Ren, et al.
Targeting the Hepatic Circadian Clock Concomitant With Tyrosine Kinase Inhibition Reverses Late-Stage Hepatocellular Carcinoma, Baharan Fekry, Savera Aggarwal, Rachel Van Drunen, et al.
The CGAS-STING1 Pathway as a Mediator of Innate Immune Response in Cardiovascular Disease, Leila Rouhi, Priyatansh Gurha, and Ali J Marian
The Genomes of Nematode-Trapping Fungi Provide Insights Into the Origin and Diversification of Fungal Carnivorism, Yani Fan, Minghao Du, Weiwei Zhang, et al.
The microRNA miR-30a Blocks Adipose Tissue Fibrosis Accumulation in Obesity, Pradip K Saha, Robert Sharp, Aaron R Cox, et al.
The Unfolded Protein Response-Novel Mechanisms, Challenges, and Key Considerations for Therapeutic Intervention, P M Quan Mai, Tam-Anh Truong, Sai Kumar Samala, et al.
Three-Dimensional Printed Models to Accelerate Resident Surgical Learning Curve for Standard Endoscopic Sinus Surgery Techniques, Jumah G Ahmad, Alexander J Citardi, Amber U Luong, et al.
Transcutaneous Spinal Stimulation Paired With Visual Feedback Facilitates Retention of Improved Weight Transfer Toward the Affected Side in People Post-Stroke, Hyunje Park, Beom-Chan Lee, Dimitry Sayenko, et al.
Type 2 Diabetes Polygenic Risk Score Interactions with Lifestyle Risk Factors in Black Americans, Ashley W Scadden, Aastha Kakar, Elizabeth M Litkowski, et al.
Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants, Kruthika R Iyer, Shoa L Clarke, Rodrigo Guarischi-Sousa, et al.
Utilization of Outpatient Mental Health Services During and 2 Years after the COVID-19 Pandemic, Michelle A Hayek, Hye-Chung Kum, Sulki Park, et al.
Whole Genome Sequence Analysis of Low-Density Lipoprotein Cholesterol Across 246 K Individuals, Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, et al.
Whole-Genome Sequence-Based Association Analysis of African American Individuals With Bipolar Disorder and Schizophrenia, Runjia Li, Sarah A Gagliano Taliun, Kevin Liao, et al.
Whole Genome Sequencing Analysis of Body Mass Index Identifies Novel African Ancestry-Specific Risk Allele, Xinruo Zhang, Jennifer A Brody, Mariaelisa Graff, et al.