The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2024
DNA Methylation in Aging and Alzheimer's Disease, Raymond Cheng, Jingmin Shu, Hai Chen, et al.
Dopaminergic Neurons in Zona Incerta Drives Appetitive Self-Grooming, Zhiying Jiang, Michelle He, Claire Young, et al.
Efficient Gene Knockout and Genetic Interaction Screening Using the in4mer CRISPR/Cas12a Multiplex Knockout Platform, Nazanin Esmaeili Anvar, Chenchu Lin, Xingdi Ma, et al.
Endolysosomal Trafficking Controls Yolk Granule Biogenesis in Vitellogenic Drosophila Oocytes, Yue Yu, Dongsheng Chen, Stephen M Farmer, et al.
Endothelial-specific Telomerase Inactivation Causes Telomere-independent Cell Senescence and Multi-organ Dysfunction Characteristic of Aging, Zhanguo Gao, Rafael Bravo Santos, Joseph Rupert, et al.
Endotrophin, a Key Marker and Driver for Fibroinflammatory Disease, Kim Henriksen, Federica Genovese, Alexander Reese-Petersen, et al.
Endotrophin as a Biomarker for Severe Acute Kidney Injury and Major Adverse Kidney Events, Alexander H Flannery, Dawei Bu, Madison Botkins, et al.
Evaluating Performance and Applications of Sample-Wise Cell Deconvolution Methods on Human Brain Transcriptomic Data, Rujia Dai, Tianyao Chu, Ming Zhang, et al.
Exploring the Potential of Epiregulin and Amphiregulin as Prognostic, Predictive, and Therapeutic Targets in Colorectal Cancer, Cara Guernsey-Biddle, Peyton High, and Kendra S Carmon
Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol, Yiyi Zhang, Jacqueline S Dron, Brandon K Bellows, et al.
Fbpp: Software To Design Pcr Primers and Probes For Nucleic Acid Base Detection of Foodborne Pathogens, Mohamed A Soliman, Mohamed S Azab, Hala A Hussein, et al.
FC Engineering by Monoclonal Mammalian Cell Display for Improved Affinity and Selectivity Towards FcγRs, Zening Wang, Minhyo Kang, Afshin Ebrahimpour, et al.
FC Gamma Receptors Promote Antibody-Induced LILRB4 Internalization and Immune Regulation of Monocytic AML, Joshua W Morse, Xun Gui, Mi Deng, et al.
Feasible Diet and Circadian Interventions Reduce In Vivo Progression of FLT3-ITD-Positive Acute Myeloid Leukemia, Megan Rodriguez, Baharan Fekry, Brianna Murphy, et al.
Generation of Protease Inhibitory Antibodies by Functional In Vivo Selection, Ki Baek Lee and Xin Ge
Genetic Regulation of Human Brain Proteome Reveals Proteins Implicated in Psychiatric Disorders, Jie Luo, Ling Li, Mingming Niu, et al.
Genetic Risk Factors Underlying White Matter Hyperintensities and Cortical Atrophy, Yash Patel, Jean Shin, Eeva Sliz, et al.
Genetic Variants For Head Size Share Genes and Pathways With Cancer, Maria J Knol, Raymond A Poot, Tavia E Evans, et al.
Genome-Wide Association Study Meta-Analysis of Neurofilament Light (NFL) Levels in Blood Reveals Novel Loci Related to Neurodegeneration, Shahzad Ahmad, Mohammad Aslam Imtiaz, Aniket Mishra, et al.
Global Trend in Exosome Isolation and Application: An Update Concept in Management of Diseases, Mohammadhassan Omrani, Hanieh Beyrampour-Basmenj, Rana Jahanban-Esfahlan, et al.
G Protein Selectivity Profile of GPR56/ADGRG1 and Its Effect on Downstream Effectors, Raida Jallouli, Ana L Moreno-Salinas, Andréanne Laniel, et al.
Human Brain Glycoform Coregulation Network and Glycan Modification Alterations in Alzheimer's Disease, Qi Zhang, Cheng Ma, Lih-Shen Chin, et al.
Hunting for Heroes: Brain Neurons Mediating GLP-1R Agonists in Obesity Treatment, Yuhan Cao and Qingchun Tong
Inter-Individual Variations in Circadian Misalignment-Induced NAFLD Pathophysiology in Mice, Nobuya Koike, Yasuhiro Umemura, Hitoshi Inokawa, et al.
Intracranial Volume Is Driven by Both Genetics and Early Life Exposures: The SOL-INCA-MRI Study, Tamar Sofer, Einat Granot-Hershkovitz, Wassim Tarraf, et al.