The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2024
DNA-Binding Proteins From MBD Through ZF to BEN: Recognition of Cytosine Methylation Status by One Arginine With Two Conformations, Xing Zhang, Robert M Blumenthal, and Xiaodong Cheng
DNA Methylation in Aging and Alzheimer's Disease, Raymond Cheng, Jingmin Shu, Hai Chen, et al.
Dopaminergic Neurons in Zona Incerta Drives Appetitive Self-Grooming, Zhiying Jiang, Michelle He, Claire Young, et al.
Dysregulation of Epigenetic Modifications in Inborn Errors of Immunity, Zhongyao Xiao, Rongjing He, Zihan Zhao, et al.
Editorial: Advances and Methods in Mesenchymal Stem Cells, Pamela L Wenzel
Editorial: Gene-Based Renaming of Human Diseases, Ali J Marian
Efficient Gene Knockout and Genetic Interaction Screening Using the in4mer CRISPR/Cas12a Multiplex Knockout Platform, Nazanin Esmaeili Anvar, Chenchu Lin, Xingdi Ma, et al.
Endolysosomal Trafficking Controls Yolk Granule Biogenesis in Vitellogenic Drosophila Oocytes, Yue Yu, Dongsheng Chen, Stephen M Farmer, et al.
Endothelial-specific Telomerase Inactivation Causes Telomere-independent Cell Senescence and Multi-organ Dysfunction Characteristic of Aging, Zhanguo Gao, Rafael Bravo Santos, Joseph Rupert, et al.
Endotrophin, a Key Marker and Driver for Fibroinflammatory Disease, Kim Henriksen, Federica Genovese, Alexander Reese-Petersen, et al.
Endotrophin as a Biomarker for Severe Acute Kidney Injury and Major Adverse Kidney Events, Alexander H Flannery, Dawei Bu, Madison Botkins, et al.
Epigenetic Regulation of Heart Failure, Manisha Deogharia and Priyatansh Gurha
Evaluating Performance and Applications of Sample-Wise Cell Deconvolution Methods on Human Brain Transcriptomic Data, Rujia Dai, Tianyao Chu, Ming Zhang, et al.
Exploring the Potential of Epiregulin and Amphiregulin as Prognostic, Predictive, and Therapeutic Targets in Colorectal Cancer, Cara Guernsey-Biddle, Peyton High, and Kendra S Carmon
Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol, Yiyi Zhang, Jacqueline S Dron, Brandon K Bellows, et al.
FC Engineering by Monoclonal Mammalian Cell Display for Improved Affinity and Selectivity Towards FcγRs, Zening Wang, Minhyo Kang, Afshin Ebrahimpour, et al.
FC Gamma Receptors Promote Antibody-Induced LILRB4 Internalization and Immune Regulation of Monocytic AML, Joshua W Morse, Xun Gui, Mi Deng, et al.
Feasible Diet and Circadian Interventions Reduce In Vivo Progression of FLT3-ITD-Positive Acute Myeloid Leukemia, Megan Rodriguez, Baharan Fekry, Brianna Murphy, et al.
Fetal Abdominal Obesity in Women With One Value Abnormality on Diagnostic Test for Gestational Diabetes Mellitus, Wonjin Kim, Soo Kyung Park, and Yoo Lee Kim
Gene Editing-Based Targeted Integration for Correction of Wiskott-Aldrich Syndrome, Melissa Pille, John M Avila, So Hyun Park, et al.
Generation of Protease Inhibitory Antibodies by Functional In Vivo Selection, Ki Baek Lee and Xin Ge
Genetic Regulation of Human Brain Proteome Reveals Proteins Implicated in Psychiatric Disorders, Jie Luo, Ling Li, Mingming Niu, et al.
Genetic Risk Factors Underlying White Matter Hyperintensities and Cortical Atrophy, Yash Patel, Jean Shin, Eeva Sliz, et al.
Genetic Variants For Head Size Share Genes and Pathways With Cancer, Maria J Knol, Raymond A Poot, Tavia E Evans, et al.
Genome-Wide Association Study Meta-Analysis of Neurofilament Light (NFL) Levels in Blood Reveals Novel Loci Related to Neurodegeneration, Shahzad Ahmad, Mohammad Aslam Imtiaz, Aniket Mishra, et al.