The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2024
MiR-29 and MiR-140 Regulate TRAIL-Induced Drug Tolerance In Lung Cancer, Suyeon Kim, Ki Wook Lee, Yongjin Yoo, et al.
Mitochondrial Permeability Transition Dictates Mitochondrial Maturation Upon Switch in Cellular Identity of Hematopoietic Precursors, Sandeep P Dumbali, Paulina D Horton, Travis I Moore, et al.
Multi-omics and Pathway Analyses of Genome-Wide Associations Implicate Regulation and Immunity in Verbal Declarative Memory Performance, Hao Mei, Jeannette Simino, Lianna Li, et al.
Multivalent Cytomegalovirus Glycoprotein B Nucleoside Modified mRNA Vaccines Did Not Demonstrate a Greater Antibody Breadth, Hsuan-Yuan Wang, Leike Li, Cody S Nelson, et al.
Neoantigen-Specific Cytotoxic TR1 CD4 T Cells Suppress Cancer Immunotherapy, Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, et al.
Neural Circuits Expressing the Serotonin 2C Receptor Regulate Memory in Mice and Humans, Hesong Liu, Yang He, Hailan Liu, et al.
One Form and Two Functions: MBD of SETDB2 Is a Protein-Interacting Domain, Jujun Zhou, Taiping Chen, and Xiaodong Cheng
One-Step Production of Fully Biotinylated and Glycosylated Human FC Gamma Receptors, Minhyo Kang, Zening Wang, and Xin Ge
Persistent Microbial Infections and Idiopathic Pulmonary Fibrosis – An Insight Into Non-typeable Haemophilus Influenza Pathogenesis, Anthony Shadid, Haydn E Rich, Hunter DeVaughn, et al.
Persistent Tailoring of MSC Activation Through Genetic Priming, Michael A Beauregard, Guy C Bedford, Daniel A Brenner, et al.
Polygenic Risk Scores and Extreme Coronary Artery Calcium Phenotypes (CAC=0 and CAC≥1000) in Adults ≥75 Years Old: The ARIC Study, Omar Dzaye, Alexander C Razavi, Zeina A Dardari, et al.
Protein SUMOylation Promotes cAMP-Independent EPAC1 Activation, Wenli Yang, Fang C Mei, Wei Lin, et al.
Proteomics in Orthopedic Research: Recent Studies and Their Translational Implications, George Li, Argyrios Stampas, Yoshihiro Komatsu, et al.
Radiation-Induced Macrovessel/Microvessel Disease, Jun-Ichi Abe, Bryan G Allen, Andreas M Beyer, et al.
Rare Variant Contribution to the Heritability of Coronary Artery Disease, Ghislain Rocheleau, Shoa L Clarke, Gaëlle Auguste, et al.
Risk Factors for Blunt Cerebrovascular Injury in a Cohort of Pediatric Patients With Cervical Seat Belt Sign, Daniel A Najar, Marylou Cardenas-Turanzas, Jadeyn King, et al.
SARS-CoV-2 Omicron: Viral Evolution, Immune Evasion, and Alternative Durable Therapeutic Strategies, Hailong Guo, Sha Ha, Jason W Botten, et al.
SART3 Reads Methylarginine-Marked Glycine- and Arginine-Rich Motifs, Yalong Wang, Jujun Zhou, Wei He, et al.
Somatostatin Receptor Subtype-2 Targeting System for Specific Delivery of Temozolomide, Solmaz AghaAmiri, Sukhen C Ghosh, Servando Hernandez Vargas, et al.
Tau Is Required for Glial Lipid Droplet Formation and Resistance to Neuronal Oxidative Stress, Lindsey D Goodman, Isha Ralhan, Xin Li, et al.
The Evolving Paradigm of Antibody-Drug Conjugates Targeting the ErbB/HER Family of Receptor Tyrosine Kinases, Peyton High, Cara Guernsey, Shraddha Subramanian, et al.
The Hepatokine Orosomucoid 2 Mediates Beneficial Metabolic Effects of Bile Acids, Sung Ho Lee, Ji Ho Suh, Mi Jeong Heo, et al.
The ICF Syndrome Protein CDCA7 Harbors a Unique DNA Binding Domain That Recognizes a CpG Dyad in the Context of a Non-B DNA, Swanand Hardikar, Ren Ren, Zhengzhou Ying, et al.
Transcriptional Signature of Durable Effector T Cells Elicited By A Replication Defective HCMV Vaccine, Xiaohua Ye, David J H Shih, Zhiqiang Ku, et al.
Translational Potential of a Contrast Agent for FGS Applications in pNETs, Solmaz AghaAmiri, Jeannelyn S Estrella, Servando Hernandez Vargas, et al.