The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2025
Regional Heterogeneity of the Blood-Brain Barrier, Marie Blanchette, Kaja Bajc, Benjamin D Gastfriend, et al.
Relationship Between TRPM4 RS8104571 Genotype, Circulating TRPM4 and SUR1, and Clinical Outcome Following Traumatic Brain Injury, Joseph D Krocker, Madeline E Cotton, Janet R Ashley, et al.
Restricting Metabolic Plasticity Enhances Stress Adaptation Through the Modulation of Pdh and HIF1A in TRAP1-Depleted Colon Cancer, Hong-Yuan Tsai, Miao-Hsueh Chen, Jihye Yun, et al.
Rezafungin for Suppressive Therapy of Candida auris in a Patient With a Left Ventricular Assist Device (LVAD), Matthew A Stack, Luis Ostrosky-Zeichner, Rodrigo Hasbun, et al.
Rhythm Is Essential: Unraveling the Relation Between the Circadian Clock and Cancer, Olajumoke Ogunlusi, Abantika Ghosh, Mrinmoy Sarkar, et al.
Safety of Indocyanine Green Microdosing for Clinical Imaging of CSF Ventricular Dynamics and Extracranial Outflow, Miriam Zamorano, Banghe Zhu, Ahmed T Massoud, et al.
Secretogranin 2 Binds LILRB4 Resulting in Immunosuppression, Xing Yang, Ryan Huang, Meng Fang, et al.
Senescence Caused by Telomerase Inactivation in Myeloid, Mesenchymal, and Endothelial Cells Has Distinct Effects on Cancer Progression, Joseph Rupert, Zhanguo Gao, Yongmei Yu, et al.
Serotonin Neurons Integrate GABA and Dopamine Inputs To Regulate Meal Initiation, Kristine M Conde, HueyZhong Wong, Shuzheng Fang, et al.
Serum Endotrophin Relates to Blood Pressure in Young South Asian Women but Not White Women: Evidence of Ethnic Variation in Its Early Vascular Implications, Ravi Retnakaran, Dawei Bu, Jiajie Pu, et al.
SLB-msSIM: A Spectral Library-Based Multiplex Segmented SIM Platform for Single-Cell Proteomic Analysis, Lakmini Senavirathna, Cheng Ma, Van-An Duong, et al.
Somatostatin Receptor 2 Overexpression in Hepatocellular Carcinoma: Implications for Cancer Biology and Therapeutic Applications, Servando Hernandez Vargas, Solmaz Aghaamiri, Jack T Adams, et al.
SSTR2-Targeted Theranostics in Hepatocellular Carcinoma, Majid Momeny, Solmaz AghaAmiri, Servando Hernandez Vargas, et al.
Stereotactic Body Radiotherapy vs Sorafenib Alone in Hepatocellular Carcinoma: The NRG Oncology/RTOG 1112 Phase 3 Randomized Clinical Trial, Laura A Dawson, Kathryn A Winter, Jennifer J Knox, et al.
Structural Basis for the Substrate Specificity of Helix pomatia AMP Deaminase and a Chimeric ADGF Adenosine Deaminase, Gundeep Kaur, John R Horton, George Tzertzinis, et al.
SWI/SNF Complex-Mediated ZNF410 Cooperative Binding Maintains Chromatin Accessibility and Enhancer Activity, Siyuan Xu, Chuxuan Peng, Ren Ren, et al.
Systemic Antitumor Immune Response of Doped Yttria Nanoscintillators Under Low-Dose X-Ray Irradiation, Onur Sahin, Yuri Mackeyev, Geraldine V Vijay, et al.
Targeting the Hepatic Circadian Clock Concomitant With Tyrosine Kinase Inhibition Reverses Late-Stage Hepatocellular Carcinoma, Baharan Fekry, Savera Aggarwal, Rachel Van Drunen, et al.
The CGAS-STING1 Pathway as a Mediator of Innate Immune Response in Cardiovascular Disease, Leila Rouhi, Priyatansh Gurha, and Ali J Marian
The Genomes of Nematode-Trapping Fungi Provide Insights Into the Origin and Diversification of Fungal Carnivorism, Yani Fan, Minghao Du, Weiwei Zhang, et al.
The microRNA miR-30a Blocks Adipose Tissue Fibrosis Accumulation in Obesity, Pradip K Saha, Robert Sharp, Aaron R Cox, et al.
The Role of Recruited Adipose Stromal Cells and Their Fibroblastic Differentiation in Cancer, Lingyi Cai, Mikhail G Kolonin, and Dimitris Anastassiou
The Tweak/Fn14 Signaling Mediates Skeletal Muscle Wasting During Cancer Cachexia, Meiricris Tomaz da Silva, Anirban Roy, Anh Tuan Vuong, et al.
The Unfolded Protein Response-Novel Mechanisms, Challenges, and Key Considerations for Therapeutic Intervention, P M Quan Mai, Tam-Anh Truong, Sai Kumar Samala, et al.
Three-Dimensional Printed Models to Accelerate Resident Surgical Learning Curve for Standard Endoscopic Sinus Surgery Techniques, Jumah G Ahmad, Alexander J Citardi, Amber U Luong, et al.