The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2023
Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk, Deirdre K Tobias, Alisa K Manning, Jennifer Wessel, et al.
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile- Specific DNA Adenine Methyltransferase, Jujun Zhou, Youchao Deng, Iredia D Iyamu, et al.
Comprehensive Analysis of the Prognostic Significance of the TRIM Family in the Context of TP53 Mutations in Cancers, Trung Vu, Annaliese Fowler, and Nami McCarty
Consensus On The Ras Dimerization Hypothesis: Strong Evidence For Lipid-Mediated Clustering But Not For G-Domain-Mediated Interactions, Dhirendra K Simanshu, Mark R Philips, and John F Hancock
Coronary Heart Disease and Ischemic Stroke Polygenic Risk Scores and atherosclerotic Cardiovascular Disease in a Diverse, Population-Based Cohort Study, Allison Bebo, Jamie A Jarmul, Mark J Pletcher, et al.
Dermatological Concerns for Women and Girls With Turner Syndrome, David Rodriguez-Buritica, Meaghan Mones, Siddharth K Prakash, et al.
Design and Development of a Clot Burst Pressure Device to Investigate Resuscitation Strategies, Atharwa R Mankame, Jacob B Schriner, Max A Skibber, et al.
Dexmedetomidine Alters The Inflammatory Profile of Rat Microglia In Vitro, Michael C Scott, Candice M Haase, Scott D Olson, et al.
Direct Modulators of K-Ras–Membrane Interactions, Johannes Morstein, Rebika Shrestha, Que N Van, et al.
Disease Modeling and Gene Correction of LGMDR21 iPSCs Elucidates the Role of POGLUT1 in Skeletal Muscle Maintenance, Regeneration, and the Satellite Cell Niche, Jose L Ortiz-Vitali, Jianbo Wu, Nasa Xu, et al.
DLX2 Promotes Osteosarcoma Epithelial-Mesenchymal Transition and Doxorubicin Resistance by Enhancing HOXC8-CDH2 Axis, Boya Zhang, Xinhui Du, Yichao Fan, et al.
DNA Methylation Analysis Is Used To Identify Novel Genetic Loci Associated With Circulating Fibrinogen Levels in Blood, Julie Hahn, Jan Bressler, Arce Domingo-Relloso, et al.
Dural Sinus Narrowing In Patients With Spontaneous Anterior Skull Base Cerebrospinal Fluid Leak, Karim W Asi, Brian H Cameron, Elliot R Friedman, et al.
Endotrophin Neutralization Through Targeted Antibody Treatment Protects From Renal Fibrosis in a Podocyte Ablation Model, Yu A An, Wei Xiong, Shiuhwei Chen, et al.
Energy Intake at the Intersection of the Clock and Ageing, Kristin Eckel-Mahan
Enniatin a Inhibits the Chaperone Hsp90 and Unleashes the Immune System Against Triple-Negative Breast Cancer, Nada H Eisa, Vincent M Crowley, Asif Elahi, et al.
Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9, Antoine Weihs, Layal Chaker, Tiphaine C Martin, et al.
Evaluating the Use of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, Matthew O Goodman, Alyna T Khan, et al.
Expansion of the Genotypic and Phenotypic Spectrum of CTCF-Related Disorder Guides Clinical Management: 43 New Subjects and a Comprehensive Literature Review, Hannah Gabriela Valverde de Morales, Hsiao-Lin V Wang, Kathryn Garber, et al.
Extracellular Matrix (ECM) and Fibrosis in Adipose Tissue: Overview and Perspectives, Kai Sun, Xin Li, and Philipp E Scherer
Gender Differences in a Mouse Model of Hepatocellular Carcinoma Revealed Using Multi-Modal Imaging, Brian J Engel, Vincenzo Paolillo, Md Nasir Uddin, et al.
Gene-Educational Attainment Interactions in a Multi-population Genome-Wide Meta-Analysis Identify Novel Lipid Loci, Lisa de Las Fuentes, Karen L Schwander, Michael R Brown, et al.
Genetic Associations Between Sleep Traits and Cognitive Ageing Outcomes in the Hispanic Community Health Study/Study of Latinos, Yuan Zhang, Michael Elgart, Einat Granot-Hershkovitz, et al.
Genetic Loci of Beta-Aminoisobutyric Acid Are Associated With Aging-Related Mild Cognitive Impairment, Einat Granot-Hershkovitz, Brian Spitzer, Yunju Yang, et al.
Glycolysis Regulates Kras Plasma Membrane Localization and Function Through Defined Glycosphingolipids, Junchen Liu, Ransome van der Hoeven, Walaa E Kattan, et al.