The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.
Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.
Submissions from 2024
A Review of Image Sensors Used in Near-Infrared and Shortwave Infrared Fluorescence Imaging, Banghe Zhu and Henry Jonathan
A Simple and Rapid In Vitro Assay for Identification of Direct Inhibitors of O6-Methylguanine-DNA Methyltransferase, Vahid Khalaj, Solmaz AghaAmiri, Sukhen C Ghosh, et al.
Association Between Symptom Burden and Early Lymphatic Abnormalities After Regional Nodal Irradiation for Breast Cancer, Alison K Yoder, Tianlin Xu, Peter Youssef, et al.
Association of Common and Rare Variants With Alzheimer’s Disease in More Than 13,000 Diverse Individuals With Whole-Genome Sequencing From the Alzheimer’s Disease Sequencing Project, Wan-Ping Lee, Seung Hoan Choi, Margaret G Shea, et al.
Association of Common and Rare Variants With Alzheimer’s Disease in More Than 13,000 Diverse Individuals With Whole-Genome Sequencing From the Alzheimer’s Disease Sequencing Project, Wan-Ping Lee, Seung Hoan Choi, Margaret G Shea, et al.
Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia, Matthew P Pase, Jayandra J Himali, Raquel Puerta, et al.
A Tetravalent Nanovaccine That Inhibits Growth of HPV-Associated Head and Neck Carcinoma via Dendritic and T Cell Activation, Romano Josi, Daniel E Speiser, Simone de Brot, et al.
Autologous Bone Marrow Mononuclear Cells to Treat Severe Traumatic Brain Injury in Children, Charles S Cox, David M Notrica, Jenifer Juranek, et al.
Azithromycin Reduces Hemoglobin-Induced Innate Neuroimmune Activation, Chirayu D Pandya, Hemendra J Vekaria, Miriam Zamorano, et al.
BIGH3 Mediates Apoptosis and Gap Junction Failure in Osteocytes During Renal Cell Carcinoma Bone Metastasis Progression, Tianhong Pan, Fengshuo Liu, Xiaoxin Hao, et al.
Biological Validation of Peak-Width of Skeletonized Mean Diffusivity as a VCID Biomarker: The MarkVCID Consortium, Alison M Luckey, Saptaparni Ghosh, Chen-Pin Wang, et al.
Blocking Oncostatin M Receptor Abrogates STAT3 Mediated Integrin Signaling and Overcomes Chemoresistance in Ovarian Cancer, Anjali Geethadevi, Zhiqiang Ku, Shirng-Wern Tsaih, et al.
C2H2 Zinc Finger Transcription Factors Associated with Hemoglobinopathies, Xing Zhang, Fangfang Xia, Xiaotian Zhang, et al.
Case Report: The Effect of Automated Manual Lymphatic Drainage Therapy on Lymphatic Contractility in 4 Distinct Cases, Melissa B Aldrich, John C Rasmussen, Ron J Karni, et al.
CCR2+ Monocytes Replenish Border-Associated Macrophages in the Diseased Mouse Brain, Lingxiao Wang, Jiaying Zheng, Shunyi Zhao, et al.
Cell-Specific Regulation of the Circadian Clock by BMAL1 in the Paraventricular Nucleus: Implications for Regulation of Systemic Biological Rhythms, Rachel Van Drunen, Yulin Dai, Haichao Wei, et al.
Cholinergic Basal Forebrain Connectivity to the Basolateral Amygdala Modulates Food Intake, Joshua Ortiz-Guzman, Jessica L Swanson, Evelyne K Tantry, et al.
Complement Immune System in Pulmonary Hypertension-Cooperating Roles of Circadian Rhythmicity in Complement-Mediated Vascular Pathology, Hunter DeVaughn, Haydn E Rich, Anthony Shadid, et al.
Consensus Pharmacophore Strategy For Identifying Novel SARS-Cov-2 Mpro Inhibitors from Large Chemical Libraries, Angel J Ruiz-Moreno, Raziel Cedillo-González, Luis Cordova-Bahena, et al.
Construction and Evaluation of a New Rat Reference Genome Assembly, GRCr8, From Long Reads and Long-Range Scaffolding, Kai Li, Melissa L Smith, J Chris Blazier, et al.
Current Diagnostic and Quantitative Techniques in the Field of Lymphedema Management: A Critical Review, Mary Vargo, Melissa Aldrich, Paula Donahue, et al.
Cytokine Release by Microglia Exposed to Neurologic Injury Is Amplified by Lipopolysaccharide, Michael C Scott, Olivia LeBlanc, Harper Day, et al.
Data Normalization for Addressing the Challenges in the Analysis of Single-Cell Transcriptomic Datasets, Raquel Cuevas-Diaz Duran, Haichao Wei, and Jiaqian Wu
Determinants of Mosaic Chromosomal Alteration Fitness, Yash Pershad, Taralynn Mack, Hannah Poisner, et al.
Distinct Basal Forebrain-Originated Neural Circuits Promote Homoeostatic Feeding and Suppress Hedonic Feeding in Male Mice, Hailan Liu, Jonathan C Bean, Yongxiang Li, et al.