The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases is a research institute that seeks to investigate the cause of human diseases at the cellular and molecular levels, using DNA and protein technologies to elucidate disease mechanisms.

Its development and progress are of particular interest for future planning in the increasingly important area of clinical research. The Institute endeavors to design methods of rational therapy and, wherever possible, strategies for the prevention of human diseases.

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Submissions from 2025

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Mtmr Regulates Kras Function by Controlling Plasma Membrane Levels of Phospholipids, Taylor E Lange, Ali Naji, Ransome van der Hoeven, et al.

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Multi-ancestry Genome-Wide Association Analyses Incorporating SNP-by-Psychosocial Interactions Identify Novel Loci for Serum Lipids, Amy R Bentley, Michael R Brown, Solomon K Musani, et al.

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Multifaceted Roles of Epac Signaling in Renal Functions, Oleh Pochynyuk, Kyrylo Pyrshev, and Xiaodong Cheng

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Multimeric Transcription Factor BCL11A Utilizes Two Zinc-Finger Tandem Arrays To Bind Clustered Short Sequence Motifs, John R Horton, Meigen Yu, Jujun Zhou, et al.

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Multimodal Approach in Distinguishing and Managing Uterine Arteriovenous Malformation: A Case Report, Sajeev Sridhar, Roman Sukhovershin, and John A Hancock

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Muscle-Specific ERRγ Activation Mitigates Muscle Atrophy After ACL Injury, Aiping Lu, Katie J Sikes, Ping Guo, et al.

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Mycobacterium chelonae Outbreak Investigation at a Quaternary Pediatric Hospital Following the Opening of a Leed-Certified Critical Care Tower: Where Does Water Sustainability Intersect With Infection Control?, Andrea L Ankrum, Silvia M Caceres, Michael Torsell, et al.

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Novel Physical and Biological Applications of Carbon Ion Radiotherapy, Danushka Seneviratne, Prapannajeet Biswal, and Sunil Krishnan

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Nuclear poly(A)-Binding Protein and Nucleolin Utilize Their RNA Recognition Motifs to Read Par Chains, Leilei Shi, Morgan Dasovich, John R Horton, et al.

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Oligomeric Cystatin C Supports the Immunosuppressive Activity of Myeloid Cells Through Interaction With Inhibitory Receptors, Chengcheng Zhang, Yubo He, Xiaoye Liu, et al.

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Optogenetic Activation of Cortical Microglia Promotes Neuronal Activity and Pain Hypersensitivity, Min-Hee Yi, Yi Liu, Yong U Liu, et al.

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Perioperative Fluid Therapy Impairs Lymphatic Pump Function in Male Rats, Rebecca C Harlow-Adamek, Reetu Singh, Randolph H Stewart, et al.

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Plasma Proteomic Characterization of Motoric Cognitive Risk and Mild Cognitive Impairment, Gabriela T Gomez, Sanish Sathyan, Jingsha Chen, et al.

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Polygenic Prediction of Body Mass Index and Obesity Through the Life Course and Across Ancestries, Roelof A J Smit, Kaitlin H Wade, Qin Hui, et al.

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Polygenic Scores for Obstructive Sleep Apnoea Reveal Pathways Contributing to Cardiovascular Disease, Nuzulul Kurniansyah, Satu J Strausz, Geetha Chittoor, et al.

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Preclinical Evaluation of Closed Incisional Negative Pressure Therapy on Post-Surgical Oedema and Lymphatic Activity, John C Rasmussen, Marisa Schmidt, Janelle E Morton, et al.

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Predicting Sinonasal Inverted Papilloma Attachment Using Machine Learning: Current Lessons and Future Directions, Sean P McKee, Xiaomin Liang, William C Yao, et al.

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Prefrontal Cortex Astrocytes Modulate Distinct Neuronal Populations To Control Anxiety-Like Behavior, Eunyoung Kim, Hairuo Du, Yanqi Tan, et al.

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Prevalence of Local IgE Elevation and Its Effect on Intranasal Capsaicin Therapy in the Nonallergic Rhinitis Population, Kunal R Shetty, Salman Hasan, Christopher Bankston, et al.

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Principles and Practice in Pediatric Vascular Trauma: Part 1: Scope of Problem, Team Structure, Multidisciplinary Dynamics, and Solutions, Matthew T Harting, Natalie A Drucker, Mary T Austin, et al.

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Prolonged Exposure to Food Odors Suppresses Feeding via an Olfactory Bulb-to-Hypothalamus Circuit, Yao Liu, Hailan Liu, Huey-Xian Kelly Wong, et al.

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Proteogenomics in Cerebrospinal Fluid and Plasma Reveals New Biological Fingerprint of Cerebral Small Vessel Disease, Ilana Caro, Daniel Western, Shinichi Namba, et al.

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Proteomic Perspectives on KRAS-Driven Cancers and Emerging Therapeutic Approaches, Ramesh Karki, Ru Chen, and Sheng Pan

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RBM39 Contributes to MGMT Maintenance in Response to Temozolomide-Induced DNA Damage, Vahid Khalaj, Jack T Adams, Solmaz AghaAmiri, et al.

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Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease, Bernardo Casso-Chapa, Norma Alicia Vazquez González, Nhat-Tu Le, et al.